Severe hypoalphalipoproteinemia in mice expressing human hepatic lipase deficient in binding to heparan sulfate proteoglycan

Journal of Biological Chemistry

Volumn 279, Issue 41, 2004, Pages 42403-42409

  Brown, Robert J ^a,c   Gauthier, André ^a,c   Parks, Robin J ^b,c   McPherson, Ruth ^a,c   Sparks, Daniel L ^a,c   Schultz, Joshua R ^a,c   Yao, Zemin ^a,c  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; CELLS; CHOLESTEROL; PATIENT TREATMENT; PHOSPHOLIPIDS; VIRUSES;

HIGH DENSITY LIPOPROTEINS (HDL); HUMAN HEPATIC LIPASE (HHL);

ENZYMES;

ADENOVIRUS VECTOR; ANTILIPEMIC AGENT; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; APOLIPOPROTEIN E; CHIMERIC PROTEIN; CHOLESTEROL; HEPARIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER TRIACYLGLYCEROL LIPASE; LUCIFERASE; PHOSPHOLIPID; PROTEOHEPARAN SULFATE; SODIUM CHLORIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL ISOLATION; CELL LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; FEMALE; GENE TRANSFER; HYPOALPHALIPOPROTEINEMIA; HYPOLIPOPROTEINEMIA; LIPOLYSIS; LIVER CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION;

ADENOVIRIDAE; ANIMALS; APOLIPOPROTEIN A-I; CHOLESTEROL; CHOLESTEROL, HDL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HEPARAN SULFATE PROTEOGLYCANS; HEPARIN; HEPATOCYTES; LIPASE; LIPID METABOLISM; LIPIDS; LIPOPROTEINS, HDL; LIVER; MICE; MICE, INBRED C57BL; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SODIUM CHLORIDE; TIME FACTORS;

ADENOVIRIDAE; ANIMALIA; NEGIBACTERIA;

EID: 5644277554     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407748200     Document Type: Article

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