Hepatic lipase gene therapy in hepatic lipase-deficient mice: Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium

Journal of Clinical Investigation

Volumn 97, Issue 3, 1996, Pages 799-805

  Applebaum Bowden, Deborah ^a,b   Kobayashi, Junji ^a   Kashyap, Vikram S ^a   Brown, David R ^a   Berard, Annie ^a   Meyn, Susan ^a   Parrott, Catherine ^a   Maeda, Nobuyo ^c   Shamburek, Robert ^a   Brewer Jr , H Bryan ^a   Santamarina Fojo, Silvia ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Adenoviridae; Gene therapy; HDL; Hepatic lipase; Phospholipid

Indexed keywords

CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERMEDIATE DENSITY LIPOPROTEIN; LIVER TRIACYLGLYCEROL LIPASE; PHOSPHOLIPASE; TRIACYLGLYCEROL LIPASE;

ADENOVIRUS; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; ENZYME DEFICIENCY; EXPRESSION VECTOR; GENE THERAPY; LIPOPROTEIN METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; CHOLESTEROL; ENDOTHELIUM, VASCULAR; GENE THERAPY; HUMANS; HYPERLIPIDEMIAS; LIPASE; LIPIDS; LIPOPROTEINS; MALE; MICE; MICE, MUTANT STRAINS; PHOSPHOLIPASES; RECOMBINANT PROTEINS;

EID: 0030058583     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118479     Document Type: Article

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