Male-specific association between a γ-secretase polymorphism and premature coronary atherosclerosis

PLoS ONE

Volumn 3, Issue 11, 2008, Pages

  van Loo, Karen M J ^a   Dejaegere, Tim ^b,c   van Zweeden, Martine ^a   van Schijndel, Jessica E ^a   Wijmenga, Cisca ^d,e   Trip, Mieke D ^f   Martens, Gerard J M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GAMMA SECRETASE; PROTEIN APH1B; UNCLASSIFIED DRUG; APH 1 PROTEIN, HUMAN; APH-1 PROTEIN, HUMAN; FIBRINOGEN; HYBRID PROTEIN; MEMBRANE PROTEIN;

ADULT; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CAUCASIAN; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; EMBRYO; ENZYME ACTIVITY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUSE; MUTATIONAL ANALYSIS; NETHERLANDS; NONHUMAN; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; COHORT ANALYSIS; CORONARY ARTERY DISEASE; ENZYME SPECIFICITY; FIBROBLAST; GENETICS; METABOLISM; MIDDLE AGED; ONSET AGE; PREVALENCE; RISK FACTOR; SEX RATIO;

RATTUS NORVEGICUS;

ADULT; AGE OF ONSET; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; COHORT STUDIES; CORONARY ARTERY DISEASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FIBRINOGEN; FIBROBLASTS; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MIDDLE AGED; NETHERLANDS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; RECOMBINANT FUSION PROTEINS; RISK FACTORS; SEX DISTRIBUTION; SEX FACTORS; SUBSTRATE SPECIFICITY;

EID: 56349168558     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003662     Document Type: Article

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