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Volumn 49, Issue 1, 1997, Pages 56-61

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; FEMALE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SENILE PLAQUE;

EID: 0030752288     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.49.1.56     Document Type: Article
Times cited : (292)

References (33)
  • 1
    • 0029073383 scopus 로고
    • Genetic dissection of Alzheimer disease, a heterogeneous disorder
    • Schellenberg GD. Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc Natl Acad Sci USA 1995;92: 8552-8559.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8552-8559
    • Schellenberg, G.D.1
  • 2
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
    • Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 1995;375:754-760.
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1    Rogaev, E.I.2    Liang, Y.3
  • 3
    • 0342367816 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev EI, Sherrington R, Rogaeva EA, et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995;283:4228-4229.
    • (1995) Nature , vol.283 , pp. 4228-4229
    • Rogaev, E.I.1    Sherrington, R.2    Rogaeva, E.A.3
  • 4
    • 0027407565 scopus 로고
    • Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer's disease
    • Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high avidity binding to β-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer's disease. Proc Natl Acad Sci USA 1993;90:1977-1981.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3
  • 5
    • 0027936838 scopus 로고
    • Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease
    • Roses AD. Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J Neuropathol Exp Neurol 1994;53:429-437.
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 429-437
    • Roses, A.D.1
  • 6
    • 0028986408 scopus 로고
    • Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E
    • Castano E, Prelli F, Wisniewski T, et al. Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. Biochem J 1995;306:599-604.
    • (1995) Biochem J , vol.306 , pp. 599-604
    • Castano, E.1    Prelli, F.2    Wisniewski, T.3
  • 9
    • 0028822219 scopus 로고
    • Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
    • Holtzman D, Pitas R, Killbridge J, et al. Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. Proc Natl Acad Sci USA 1995;92: 9480-9484.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9480-9484
    • Holtzman, D.1    Pitas, R.2    Killbridge, J.3
  • 10
    • 0028850374 scopus 로고
    • Stable expression and secretion of apolipoprotein E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth
    • Bellosta S, Nathan BP, Orth M, Dong LM, Mahley RW, Pitas RE. Stable expression and secretion of apolipoprotein E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth. J Biol Chem 1995;270:27063-27071.
    • (1995) J Biol Chem , vol.270 , pp. 27063-27071
    • Bellosta, S.1    Nathan, B.P.2    Orth, M.3    Dong, L.M.4    Mahley, R.W.5    Pitas, R.E.6
  • 11
    • 0026693345 scopus 로고
    • 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain
    • 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain. Am J Pathol 1992;141:37-42.
    • (1992) Am J Pathol , vol.141 , pp. 37-42
    • Wolf, B.B.1    Lopes, M.B.S.2    VandenBerg, S.R.3    Gonias, S.L.4
  • 13
    • 0029118511 scopus 로고
    • LDL receptor-related protein: A multiligand receptor for lipoprotein and proteinase catabolism
    • Strickland DK, Kounnas MZ, Argraves SW. LDL receptor-related protein: a multiligand receptor for lipoprotein and proteinase catabolism. FASEB J 1995;9:890-898.
    • (1995) FASEB J , vol.9 , pp. 890-898
    • Strickland, D.K.1    Kounnas, M.Z.2    Argraves, S.W.3
  • 14
    • 0029128232 scopus 로고
    • LDL-receptor-related protein, a multifunctional apoE receptor, binds secreted β-amyloid precursor protein and mediated its degradation
    • Kounnas MZ, Moir RD, Rebeck GW, et al. LDL-receptor-related protein, a multifunctional apoE receptor, binds secreted β-amyloid precursor protein and mediated its degradation. Cell 1995;82:331-340.
    • (1995) Cell , vol.82 , pp. 331-340
    • Kounnas, M.Z.1    Moir, R.D.2    Rebeck, G.W.3
  • 15
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck GW, Reiter JS, Strickland DK, Hyman BT. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 1993;11:575-580.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 16
    • 0028170758 scopus 로고
    • Apolipoprotein ∈4 is associated with increased neurofibrillary pathology in Lewy body variant of Alzheimer's disease
    • Hansen LA, Galasko D, Samuel W, et al. Apolipoprotein ∈4 is associated with increased neurofibrillary pathology in Lewy body variant of Alzheimer's disease. Neurosci Lett 1994;182: 63-65.
    • (1994) Neurosci Lett , vol.182 , pp. 63-65
    • Hansen, L.A.1    Galasko, D.2    Samuel, W.3
  • 17
    • 0029666413 scopus 로고    scopus 로고
    • The apolipoprotein E ∈4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant
    • Olichney JM, Hansen LA, Galasko MD, et al. The apolipoprotein E ∈4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant. Neurology 1996;47:190-196.
    • (1996) Neurology , vol.47 , pp. 190-196
    • Olichney, J.M.1    Hansen, L.A.2    Galasko, M.D.3
  • 18
    • 0028989161 scopus 로고
    • Multiplex PCR-SSCP for simultaneous screening for mutations in several exons of p53
    • Ozcelik H, Andrulis I. Multiplex PCR-SSCP for simultaneous screening for mutations in several exons of p53. Biotechniques 1995;18:742-744.
    • (1995) Biotechniques , vol.18 , pp. 742-744
    • Ozcelik, H.1    Andrulis, I.2
  • 19
    • 0028113971 scopus 로고
    • The apolipoprotein E allele ∈4 is over-represented in patients with the Lewy body variant of Alzheimer's disease
    • Galasko D, Saitoh T, Xia Y, Thai LJ, Katzman R, Hill LR, Hansen L. The apolipoprotein E allele ∈4 is over-represented in patients with the Lewy body variant of Alzheimer's disease. Neurology 1994;44:1950-1951.
    • (1994) Neurology , vol.44 , pp. 1950-1951
    • Galasko, D.1    Saitoh, T.2    Xia, Y.3    Thai, L.J.4    Katzman, R.5    Hill, L.R.6    Hansen, L.7
  • 20
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons
    • Evans DA, Funkenstein HH, Albert MS, et al. Prevalence of Alzheimer's disease in a community population of older persons. JAMA 1989;262:2551-2556.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3
  • 21
    • 0027194791 scopus 로고
    • Gene dosage of apoliprotein E type 4 allele and risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Risch NJ, et al. Gene dosage of apoliprotein E type 4 allele and risk of Alzheimer's disease in late onset families. Science 1993;261:921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3
  • 22
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner GG, Wong CW. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1984;120: 885-890.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 23
    • 0027365822 scopus 로고
    • Increased amyloid β-peptide deposition in cerebral cortices as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
    • Schmechel DE, Saunders AM, Strittmatter WJ, et al. Increased amyloid β-peptide deposition in cerebral cortices as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993;90:9649-9653.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 24
    • 0028172032 scopus 로고
    • The role of α 2M receptor/LRP in chylomicron remnant metabolism
    • Beisiegl U, Krapp A, Weber W, Olivecrona G. The role of α 2M receptor/LRP in chylomicron remnant metabolism. Ann NY Acad Sci 1994;737:53-69.
    • (1994) Ann NY Acad Sci , vol.737 , pp. 53-69
    • Beisiegl, U.1    Krapp, A.2    Weber, W.3    Olivecrona, G.4
  • 26
    • 0029118873 scopus 로고
    • Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease
    • Okuizumi K, Onodera O, Namba Y, et al. Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease. Nature Genet 1995;11:207-209.
    • (1995) Nature Genet , vol.11 , pp. 207-209
    • Okuizumi, K.1    Onodera, O.2    Namba, Y.3
  • 27
    • 0030028429 scopus 로고    scopus 로고
    • Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease
    • Wragg M, Hutton M, Talbot C, Group. AC. Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Lancet 1996;347:509-512.
    • (1996) Lancet , vol.347 , pp. 509-512
    • Wragg, M.1    Hutton, M.2    Talbot, C.3
  • 29
    • 9444244971 scopus 로고    scopus 로고
    • Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease
    • Okuizumi K, Onodera O, Seki K, et al. Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease. Ann Neurol 1996;40:251-254.
    • (1996) Ann Neurol , vol.40 , pp. 251-254
    • Okuizumi, K.1    Onodera, O.2    Seki, K.3
  • 30
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: Genetic analysis
    • Kerem B-S, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989;245: 1073-1080.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.-S.1    Rommens, J.M.2    Buchanan, J.A.3
  • 31
    • 0028037084 scopus 로고
    • 2-macroglobulin receptor lipoprotein receptor-related protein
    • 2-macroglobulin receptor lipoprotein receptor-related protein. Genomics 1994;24:78-89.
    • (1994) Genomics , vol.24 , pp. 78-89
    • Van Leuven, F.1    Stas, L.2    Hiliken, C.3
  • 32
    • 0024847273 scopus 로고
    • Tissue-specific expression of three types of β-protein precursor mRNA: Enhancement of protease inhibitor-harboring types in Alzheimer's disease brain
    • Tanaka S, Shiojiri S, Takahashi Y, et al. Tissue-specific expression of three types of β-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain. Biochem Biophys Res Commun 1989;165: 1406-1414.
    • (1989) Biochem Biophys Res Commun , vol.165 , pp. 1406-1414
    • Tanaka, S.1    Shiojiri, S.2    Takahashi, Y.3
  • 33
    • 0025295476 scopus 로고
    • Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease
    • Johnson SA, McNeil T, Cordell B, Finch CE. Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease. Science 1990;248:854-857.
    • (1990) Science , vol.248 , pp. 854-857
    • Johnson, S.A.1    McNeil, T.2    Cordell, B.3    Finch, C.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.