Gö6976 inhibits LPS-induced microglial TNFα release by suppressing p38 MAP kinase activation

Neuroscience

Volumn 114, Issue 3, 2002, Pages 689-697

  Jeohn, G H ^a   Cooper, C L ^a,b   Jang, K J ^a,c   Liu, B ^a   Lee, D S ^a   Kim, H C ^a,c   Hong, J S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b TRUMAN STATE UNIVERSITY   (United States)

^c Kangwon National University   (South Korea)

Author keywords

Brain inflammation; Cytokine; Endotoxin; Microglia; Mitogen activated protein kinase; Mouse

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ISOENZYME; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; INFLAMMATION; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; CARBAZOLES; CELL LINE; ENZYME INHIBITORS; INDOLES; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037063691     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00356-1     Document Type: Article

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