-
1
-
-
33847387472
-
Kras(g12d) and smad4/dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas
-
Izeradjene K, Combs C, Best M et al (2007) Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas. Cancer Cell 11:229-243
-
(2007)
Cancer Cell
, vol.11
, pp. 229-243
-
-
Izeradjene, K.1
Combs, C.2
Best, M.3
-
3
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani SR, Petricoin EF, Maitra A et al (2003) Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4:437-450
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
-
4
-
-
19344362405
-
Trp53r172h and krasg12d cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
-
Hingorani SR, Wang L, Multani AS et al (2005) Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7:469-483
-
(2005)
Cancer Cell
, vol.7
, pp. 469-483
-
-
Hingorani, S.R.1
Wang, L.2
Multani, A.S.3
-
5
-
-
33645824724
-
Both p16(ink4a) and the p19(arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
-
Bardeesy N, Aguirre AJ, Chu GC et al (2006) Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci USA 103:5947-5952
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5947-5952
-
-
Bardeesy, N.1
Aguirre, A.J.2
Chu, G.C.3
-
6
-
-
0346455774
-
Activated kras and ink4a/arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
-
Aguirre J, Bardeesy N, Sinha M et al (2003) Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev 17:3112-3126
-
(2003)
Genes Dev
, vol.17
, pp. 3112-3126
-
-
Aguirre, J.1
Bardeesy, N.2
Sinha, M.3
-
7
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
DOI10.1126/Science.1164368
-
Jones S, Zhang X, Parsons DW et al (2008) Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science DOI10.1126/Science. 1164368
-
(2008)
Science
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
-
8
-
-
42149192000
-
Activated kras, but not hras or nras, may initiate tumors of endodermal origin via stem cell expansion
-
Quinlan MP, Quatela SE, Philips MR et al (2008) Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion. Mol Cell Biol 28:2659-2674
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2659-2674
-
-
Quinlan, M.P.1
Quatela, S.E.2
Philips, M.R.3
-
9
-
-
44649114063
-
Oncogenic kras induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas
-
Park SW, Davison JM, Rhee J et al (2008) Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas. Gastroenterology 134:2080-2090
-
(2008)
Gastroenterology
, vol.134
, pp. 2080-2090
-
-
Park, S.W.1
Davison, J.M.2
Rhee, J.3
-
10
-
-
54949125004
-
Analysis of ccn2 promoter activity in panc-1 cells: Regulation by ras/mek/erk
-
Pickles M, Leask A (2007) Analysis of CCN2 promoter activity in PANC-1 cells: regulation by ras/MEK/ERK. J Cell Commun Signal 1:85-90
-
(2007)
J Cell Commun Signal
, vol.1
, pp. 85-90
-
-
Pickles, M.1
Leask, A.2
-
11
-
-
33745078936
-
Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer
-
Aikawa T, Gunn J, Spong SM et al (2006) Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer. Mol Cancer Ther 5:1108-1116
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1108-1116
-
-
Aikawa, T.1
Gunn, J.2
Spong, S.M.3
-
12
-
-
34347253037
-
Oncogenic kras activates hedgehog signaling pathway in pancreatic cancer cells
-
Ji Z, Mei FC, Xie J et al (2007) Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells. J Biol Chem 282:14048-14055
-
(2007)
J Biol Chem
, vol.282
, pp. 14048-14055
-
-
Ji, Z.1
Mei, F.C.2
Xie, J.3
-
14
-
-
0036110390
-
Cyclin d regulates fgfr-1 isoforms iiic and iiib (isoform iiic enhances and fgfr1-iiib inhibits pancreatic cancer cell growth
-
Biankin AV, Biankin SA, Kench JG et al (2002) Cyclin D regulates FGFR-1 isoforms IIIc and IIIb (isoform IIIc enhances and FGFR1-IIIb inhibits pancreatic cancer cell growth. Gut 50:861-868
-
(2002)
Gut
, vol.50
, pp. 861-868
-
-
Biankin, A.V.1
Biankin, S.A.2
Kench, J.G.3
-
15
-
-
55949100561
-
Exon iii splicing of fibroblast growth factor receptor 1 is modulated by growth factors and cyclin d1
-
Chen G, Wang J, Liu Z et al (2008) Exon III splicing of fibroblast growth factor receptor 1 is modulated by growth factors and cyclin D1. Pancreas 37:159-164
-
(2008)
Pancreas
, vol.37
, pp. 159-164
-
-
Chen, G.1
Wang, J.2
Liu, Z.3
-
16
-
-
34547932065
-
Solid pseudopapillary neoplasms of the pancreas show an interruption of the wnt-signaling pathway and express gene products of 11q
-
Tiemann K, Heitling U, Kosmahl M et al (2007) Solid pseudopapillary neoplasms of the pancreas show an interruption of the Wnt-signaling pathway and express gene products of 11q. Mod Pa-thol 20:955-960
-
(2007)
Mod Pa-thol
, vol.20
, pp. 955-960
-
-
Tiemann, K.1
Heitling, U.2
Kosmahl, M.3
-
17
-
-
9144224192
-
Ink4/arf germline alterations in pancreatic cancer patients
-
Ghiorzo P, Pastorino L, Bonelli L et al (2004) INK4/ARF germline alterations in pancreatic cancer patients. Ann Oncol 15:70-78
-
(2004)
Ann Oncol
, vol.15
, pp. 70-78
-
-
Ghiorzo, P.1
Pastorino, L.2
Bonelli, L.3
-
18
-
-
0032222915
-
Novel germline p16(ink4) allele (asp145cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148
-
Moskaluk CA, Hruban H, Lietman A et al (1998) Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Hum Mutat 12:70
-
(1998)
Hum Mutat
, vol.12
, pp. 70
-
-
Moskaluk, C.A.1
Hruban, H.2
Lietman, A.3
-
19
-
-
0028308492
-
P53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in dna microdeletions
-
Redston MS, Caldas C, Seymour AB et al (1994) p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 54: 3025-3033
-
(1994)
Cancer Res
, vol.54
, pp. 3025-3033
-
-
Redston, M.S.1
Caldas, C.2
Seymour, A.B.3
-
20
-
-
53049095294
-
Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations
-
Yan W, Liu G, Scoumanne A et al (2008) Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. Cancer Res 68:6789-6796
-
(2008)
Cancer Res
, vol.68
, pp. 6789-6796
-
-
Yan, W.1
Liu, G.2
Scoumanne, A.3
-
21
-
-
34547686211
-
The role of the dna damage checkpoint pathway in intraductal papillary mucinous neoplasms of the pancreas
-
Miyasaka Y, Nagai E, Yamaguchi H et al (2007) The role of the DNA damage checkpoint pathway in intraductal papillary mucinous neoplasms of the pancreas. Clin Cancer Res 13:4371-4377
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4371-4377
-
-
Miyasaka, Y.1
Nagai, E.2
Yamaguchi, H.3
-
22
-
-
0038179900
-
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
-
Logsdon CD, Simeone DM, Binkley C et al (2003) Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 63:2649-2657
-
(2003)
Cancer Res
, vol.63
, pp. 2649-2657
-
-
Logsdon, C.D.1
Simeone, D.M.2
Binkley, C.3
-
23
-
-
4544269166
-
Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis
-
Guweidhi A, Kleeff J, Giese N et al (2004) Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis. Carcinogenesis 25:1575-1585
-
(2004)
Carcinogenesis
, vol.25
, pp. 1575-1585
-
-
Guweidhi, A.1
Kleeff, J.2
Giese, N.3
-
24
-
-
0032014216
-
Human smad3 and smad4 are sequence-specific transcription activators
-
Zawel L, Dai JL, Buckhaults P et al (1998) Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell 1:611-617
-
(1998)
Mol Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
-
25
-
-
0036848885
-
Suppression of tumorigenesis and induction of p15(ink4b) by smad4/dpc4 in human pancreatic cancer cells
-
Peng B, Fleming JB, Breslin T et al (2002) Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clin Cancer Res 8:3628-3638
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3628-3638
-
-
Peng, B.1
Fleming, J.B.2
Breslin, T.3
-
26
-
-
49249095430
-
Inhibition of stat3 tyr705 phosphorylation by smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells
-
Zhao S, Venkatasubbarao K, Lazor JW et al (2008) Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells. Cancer Res 68:4221-4228
-
(2008)
Cancer Res
, vol.68
, pp. 4221-4228
-
-
Zhao, S.1
Venkatasubbarao, K.2
Lazor, J.W.3
-
27
-
-
6044241807
-
The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: Poor prognosis in patients with pancreatic ductal adenocarcinoma
-
Ueda S, Ogata S, Tsuda H et al (2004) The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: poor prognosis in patients with pancreatic ductal adenocarcinoma. Pancreas 29: e1-8
-
(2004)
Pancreas
, vol.29
-
-
Ueda, S.1
Ogata, S.2
Tsuda, H.3
-
28
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase iii trial of the national cancer institute of canada clinical trials group
-
Moore MJ, Goldstein D, Hamm J et al (2007) Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 25:1960-1966
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
29
-
-
34548205213
-
Concomitant pancreatic activation of kras(g12d) and tgfa results in cystic papillary neoplasms reminiscent of human ipmn
-
Siveke JT, Einwächter H, Sipos B et al (2007) Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN. Cancer Cell 12: 266-279
-
(2007)
Cancer Cell
, vol.12
, pp. 266-279
-
-
Siveke, J.T.1
Einwächter, H.2
Sipos, B.3
-
30
-
-
0242690240
-
Murine pancreatic tumor cell line td2 bears the characteristic pattern of genetic changes with two independently amplified gene loci
-
Schreiner B, Greten FR, Baur DM et al (2003) Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci. Oncogene 22:6802-6809
-
(2003)
Oncogene
, vol.22
, pp. 6802-6809
-
-
Schreiner, B.1
Greten, F.R.2
Baur, D.M.3
-
31
-
-
33947322389
-
Epidermal growth factor receptor (egfr) is highly conserved in pancreatic cancer
-
Tzeng CW, Frolov A, Frolova N et al (2007) Epidermal growth factor receptor (EGFR) is highly conserved in pancreatic cancer. Surgery 141:464-469
-
(2007)
Surgery
, vol.141
, pp. 464-469
-
-
Tzeng, C.W.1
Frolov, A.2
Frolova, N.3
-
32
-
-
35248866321
-
Egfr genomic gain and aberrant pathway signaling in pancreatic cancer patients
-
Tzeng CW, Frolov A, Frolova N et al (2007) EGFR genomic gain and aberrant pathway signaling in pancreatic cancer patients. J Surg Res 143: 20-26
-
(2007)
J Surg Res
, vol.143
, pp. 20-26
-
-
Tzeng, C.W.1
Frolov, A.2
Frolova, N.3
-
33
-
-
3042743983
-
Genomic dna-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes
-
Holzmann K, Kohlhammer H, Schwaenen C et al (2004) Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes. Cancer Res 64: 4428-4433
-
(2004)
Cancer Res
, vol.64
, pp. 4428-4433
-
-
Holzmann, K.1
Kohlhammer, H.2
Schwaenen, C.3
-
34
-
-
33645748963
-
Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (iressa) in human pancreatic cancer cell lines
-
Pino MS, Shrader M, Baker CH et al (2006) Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines. Cancer Res 66:3802-3812
-
(2006)
Cancer Res
, vol.66
, pp. 3802-3812
-
-
Pino, M.S.1
Shrader, M.2
Baker, C.H.3
-
35
-
-
33846220461
-
Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas
-
Kwak EL, Jankowski J, Thayer SP et al (2006) Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas. Clin Cancer Res 12:4283-4287
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4283-4287
-
-
Kwak, E.L.1
Jankowski, J.2
Thayer, S.P.3
-
36
-
-
34548128023
-
Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells
-
Hurtado M, Lozano JJ, Castellanos E et al (2007) Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells. Gut 56:1266-1274
-
(2007)
Gut
, vol.56
, pp. 1266-1274
-
-
Hurtado, M.1
Lozano, J.J.2
Castellanos, E.3
-
38
-
-
28644440697
-
Involvement of mmp-7 in invasion of pancreatic cancer cells through activation of the egfr mediated mekerk signal transduction pathway
-
Tan X, Egami H, Abe M et al (2005) Involvement of MMP-7 in invasion of pancreatic cancer cells through activation of the EGFR mediated MEKERK signal transduction pathway. J Clin Pathol 58:1242-1248
-
(2005)
J Clin Pathol
, vol.58
, pp. 1242-1248
-
-
Tan, X.1
Egami, H.2
Abe, M.3
-
39
-
-
24344473824
-
Correlation of translocation of tight junction protein zonula occludens-1 and activation of epidermal growth factor receptor in the regulation of invasion of pancreatic cancer cells
-
Takai E, Tan X, Tamori Y et al (2005) Correlation of translocation of tight junction protein Zonula occludens-1 and activation of epidermal growth factor receptor in the regulation of invasion of pancreatic cancer cells. Int J Oncol 27: 645-651
-
(2005)
Int J Oncol
, vol.27
, pp. 645-651
-
-
Takai, E.1
Tan, X.2
Tamori, Y.3
-
40
-
-
42349093818
-
Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer
-
Jimeno A, Tan AC, Coffa J et al (2008) Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer. Cancer Res 68:2841-2849
-
(2008)
Cancer Res
, vol.68
, pp. 2841-2849
-
-
Jimeno, A.1
Tan, A.C.2
Coffa, J.3
-
41
-
-
52649173202
-
Proteasome inhibition activates epidermal growth factor receptor (egfr) and egfr-independent mitogenic kinase signaling pathways in pancreatic cancer cells
-
Sloss CM, Wang F, Liu R et al (2008) Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells. Clin Cancer Res 14:5116-5123
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5116-5123
-
-
Sloss, C.M.1
Wang, F.2
Liu, R.3
-
42
-
-
0344873744
-
Autocrine-mediated erbb-2 kinase activation of stat3 is required for growth factor independence of pancreatic cancer cell lines
-
DeArmond D, Brattain MG, Jessup JM et al (2003) Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines. Oncogene 22:7781-7795
-
(2003)
Oncogene
, vol.22
, pp. 7781-7795
-
-
DeArmond, D.1
Brattain, M.G.2
Jessup, J.M.3
-
43
-
-
34548291991
-
Overexpression of erbb2 in the exocrine pancreas induces an inflammatory response but not increased proliferation
-
Algül H, Wagner M, Lesina M et al (2007) Overexpression of ErbB2 in the exocrine pancreas induces an inflammatory response but not increased proliferation. Int J Cancer 121:1410-1416
-
(2007)
Int J Cancer
, vol.121
, pp. 1410-1416
-
-
Algül, H.1
Wagner, M.2
Lesina, M.3
-
44
-
-
33748361817
-
Inactivation of akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by her-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity
-
Buck E, Eyzaguirre A, Haley JD et al (2006) Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity. Mol Cancer Ther 5:2051-2059
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2051-2059
-
-
Buck, E.1
Eyzaguirre, A.2
Haley, J.D.3
-
45
-
-
3042561471
-
Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model
-
Büchler P, Reber HA, Lavey RS et al (2004) Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model. J Surg Res 120:295-303
-
(2004)
J Surg Res
, vol.120
, pp. 295-303
-
-
Büchler, P.1
Reber, H.A.2
Lavey, R.S.3
-
46
-
-
0037134709
-
Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us
-
Hlatky L, Hahnfeldt P, Folkman J (2002) Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 94:883-893
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 883-893
-
-
Hlatky, L.1
Hahnfeldt, P.2
Folkman, J.3
-
47
-
-
0034657029
-
High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma
-
Seo Y, Baba H, Fukuda T et al (2000) High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma. Cancer 88:2239-2245
-
(2000)
Cancer
, vol.88
, pp. 2239-2245
-
-
Seo, Y.1
Baba, H.2
Fukuda, T.3
-
48
-
-
0036894180
-
Vegf-rii influences the prognosis of pancreatic cancer
-
Büchler P, Reber HA, Büchler MW et al (2002) VEGF-RII influences the prognosis of pancreatic cancer. Ann Surg 236:738-749
-
(2002)
Ann Surg
, vol.236
, pp. 738-749
-
-
Büchler, P.1
Reber, H.A.2
Büchler, M.W.3
-
49
-
-
0842268386
-
Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells
-
Fukahi K, Fukasawa M, Neufeld G et al (2004) Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells. Clin Cancer Res 10: 581-590
-
(2004)
Clin Cancer Res
, vol.10
, pp. 581-590
-
-
Fukahi, K.1
Fukasawa, M.2
Neufeld, G.3
-
50
-
-
33644975393
-
Anti-angiogenesis therapy in pancreatic carcinoma
-
Saif MW (2006) Anti-angiogenesis therapy in pancreatic carcinoma. JOP 7:163-173
-
(2006)
JOP
, vol.7
, pp. 163-173
-
-
Saif, M.W.1
-
51
-
-
34547662268
-
Overexpression of pdgf-bb decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
-
McCarty MF, Somcio RJ, Stoeltzing O et al (2007) Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. J Clin Invest 117: 2114-2122
-
(2007)
J Clin Invest
, vol.117
, pp. 2114-2122
-
-
McCarty, M.F.1
Somcio, R.J.2
Stoeltzing, O.3
-
52
-
-
34247853560
-
An antibody directed against pdgf receptor beta enhances the antitumor and the anti-angiogenic activities of an anti-vegf receptor 2 antibody
-
Shen J, Vil MD, Zhang H et al (2007) An antibody directed against PDGF receptor beta enhances the antitumor and the anti-angiogenic activities of an anti-VEGF receptor 2 antibody. Biochem Biophys Res Commun 357:1142-1147
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 1142-1147
-
-
Shen, J.1
Vil, M.D.2
Zhang, H.3
-
53
-
-
2642547301
-
Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma
-
Esposito I, Menicagli M, Funel N et al (2004) Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma. J Clin Pathol 57:630-636
-
(2004)
J Clin Pathol
, vol.57
, pp. 630-636
-
-
Esposito, I.1
Menicagli, M.2
Funel, N.3
-
54
-
-
0035902805
-
Enhanced vegf production and decreased immunogenicity induced by tgf-beta 1 promote liver metastasis of pancreatic cancer
-
Teraoka H, Sawada T, Nishihara T et al (2001) Enhanced VEGF production and decreased immunogenicity induced by TGF-beta 1 promote liver metastasis of pancreatic cancer. Br J Cancer 85:612-617
-
(2001)
Br J Cancer
, vol.85
, pp. 612-617
-
-
Teraoka, H.1
Sawada, T.2
Nishihara, T.3
-
55
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D (2008) Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8:592-603
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
56
-
-
45549106185
-
Mutational analyses of multiple oncogenic pathways in intraductal papillary mucinous neoplasms of the pancreas
-
Schönleben F, Allendorf JD, Qiu W et al (2008) Mutational analyses of multiple oncogenic pathways in intraductal papillary mucinous neoplasms of the pancreas. Pancreas 36:168-172
-
(2008)
Pancreas
, vol.36
, pp. 168-172
-
-
Schönleben, F.1
Allendorf, J.D.2
Qiu, W.3
-
57
-
-
43349105069
-
Pik3ca, kras, and braf mutations in intraductal papillary mucinous neoplasm/carcinoma (ipmn/c) of the pancreas
-
Schönleben F, Qiu W, Remotti HE et al (2008) PIK3CA, KRAS, and BRAF mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/C) of the pancreas. Langenbecks Arch Surg 393:289-296
-
(2008)
Langenbecks Arch Surg
, vol.393
, pp. 289-296
-
-
Schönleben, F.1
Qiu, W.2
Remotti, H.E.3
-
58
-
-
42649125571
-
Differential effects of oncogenic k-ras and nras on proliferation, differentiation and tumor progression in the colon
-
Haigis KM, Kendall KR, Wang Y et al (2008) Differential effects of oncogenic K-Ras and NRas on proliferation, differentiation and tumor progression in the colon. Nat Genet 40:600-608
-
(2008)
Nat Genet
, vol.40
, pp. 600-608
-
-
Haigis, K.M.1
Kendall, K.R.2
Wang, Y.3
-
59
-
-
34447126386
-
Neurotensin is a versatile modulator of in vitro human pancreatic ductal adenocarcinoma cell (pdac) migration
-
Mijatovic T, Gailly P, Mathieu V et al (2007) Neurotensin is a versatile modulator of in vitro human pancreatic ductal adenocarcinoma cell (PDAC) migration. Cell Oncol 29:315-326
-
(2007)
Cell Oncol
, vol.29
, pp. 315-326
-
-
Mijatovic, T.1
Gailly, P.2
Mathieu, V.3
-
60
-
-
34249335357
-
Fbox protein skp2, an oncogene up-regulated in pdac, is transcriptionally regulated by the pi3k/akt1 pathway in pdac cells
-
Reichert M, Saur D, Hamacher R et al (2007) Fbox protein SKP2, an oncogene up-regulated in PDAC, is transcriptionally regulated by the PI3K/AKT1 pathway in PDAC cells. Cancer Res 67:4149-4156
-
(2007)
Cancer Res
, vol.67
, pp. 4149-4156
-
-
Reichert, M.1
Saur, D.2
Hamacher, R.3
-
61
-
-
42349112613
-
Muc1 expression is regulated by dna methylation and histone h3 lysine 9 modification in cancer cells
-
Yamada N, Nishida Y, Tsutsumida H et al (2008) MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells. Cancer Res 68:2708-2716
-
(2008)
Cancer Res
, vol.68
, pp. 2708-2716
-
-
Yamada, N.1
Nishida, Y.2
Tsutsumida, H.3
-
62
-
-
33748482616
-
Muc2 expression is regulated by histone h3 modification and dna methylation in pancreatic cancer
-
Yamada N, Hamada T, Goto M et al (2006) MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. Int J Cancer 119:1850-1857
-
(2006)
Int J Cancer
, vol.119
, pp. 1850-1857
-
-
Yamada, N.1
Hamada, T.2
Goto, M.3
-
63
-
-
36249016867
-
Ap-2alpha is an important in vivo negative regulator of muc4 expression in human pancreatic tissue and that ap-2alpha may play a tumoursuppressive role in pancreatic dac
-
Fauquette V, Aubert S, Groux-Degroote S et al (2007) AP-2alpha is an important in vivo negative regulator of MUC4 expression in human pancreatic tissue and that AP-2alpha may play a tumoursuppressive role in pancreatic DAC. Carcinogenesis 28:2305-2312
-
(2007)
Carcinogenesis
, vol.28
, pp. 2305-2312
-
-
Fauquette, V.1
Aubert, S.2
Groux-Degroote, S.3
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