The genetic tidal wave finally reached our shores: Will it be the catalyst for a critical overhaul of the way we think and do science?

Mental Health and Physical Activity

Volumn 1, Issue 2, 2008, Pages 47-52

  Ekkekakis, Panteleimon ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Anxiety; Depression; Genetics; Internal validity; physical activity; Placebo

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR; ENKEPHALIN; METHIONINE; MU OPIATE RECEPTOR; PLACEBO; SEROTONIN; SERTRALINE; VALINE;

AEROBIC CAPACITY; AMINO ACID SUBSTITUTION; ANXIETY DISORDER; BEHAVIOR GENETICS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DATA ANALYSIS; DEPRESSION; EDITORIAL; ENDURANCE; EVIDENCE BASED MEDICINE; EXERCISE; EXERCISE INTENSITY; EXERCISE TOLERANCE; GENETIC POLYMORPHISM; HERITABILITY; HUMAN; KINESIOTHERAPY; MEDICAL RESEARCH; MENTAL HEALTH; META ANALYSIS; METHODOLOGY; NONHUMAN; PATIENT ATTITUDE; PATIENT SELECTION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL WELL BEING; QUALITY CONTROL; QUANTITATIVE TRAIT LOCUS MAPPING; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; SYSTEMATIC REVIEW; TREATMENT OUTCOME;

EID: 55949135052     PISSN: 17552966     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mhpa.2008.09.002     Document Type: Editorial

References (66)

1. Babyak M., Blumenthal J.A., Herman S., Khatri P., Doraiswamy M., Moore K., et al. Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosomatic Medicine 62 (2000) 633-638
2. Backhouse S.H., Ekkekakis P., Biddle S.J.H., Foskett A., and Williams C. Exercise makes people feel better but people are inactive: paradox or artifact?. Journal of Sport and Exercise Psychology 29 (2007) 498-517
3. Bedford T.G., Tipton C.M., Wilson N.C., Opplinger R.A., and Gisolfi C.V. Maximum oxygen consumption of rats and its changes with various experimental procedures. Journal of Applied Physiology 47 (1979) 1278-1283
4. Beunen G., and Thomis M. Genetic determinants of sports participation and daily physical activity. International Journal of Obesity 23 Suppl. 3 (1999) S55-S63
5. Biddle S.J.H., and Ekkekakis P. Physically active lifestyles and well-being. In: Huppert F.A., Keverne B., and Baylis N. (Eds). The science of well-being (2005), Oxford University Press, Oxford, United Kingdom 140-168
6. Biddle S.J.H., Fox K.R., Boutcher S.H., and Faulkner G.E. The way forward for physical activity and the promotion of psychological well-being. In: Biddle S.J.H., Fox K.R., and Boutcher S.H. (Eds). Physical activity and psychological well-being (2000), Routledge, London 154-168
7. Bjørnebekk A., Mathé A.A., and Brené S. The antidepressant effect of running is associated with increased hippocampal cell proliferation. International Journal of Neuropsychopharmacology 8 (2005) 357-368
8. Blumenthal J.A., Babyak M.A., Doraiswamy P.M., Watkins L., Hoffman B.M., Barbour K.A., et al. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosomatic Medicine 69 (2007) 587-596
9. Blumenthal J.A., Babyak M.A., Moore K.A., Craighead W.E., Herman S., Khatri P., et al. Effects of exercise training on older patients with major depression. Archives of Internal Medicine 159 (1999) 2349-2356
10. Bouchard C., and Rankinen T. Individual differences in response to regular physical activity. Medicine and Science in Sports and Exercise 33 (2001) S446-S451
11. Boutron I., Moher D., Altman D.G., Schulz K.F., and Ravaud P. Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Annals of Internal Medicine 148 (2008) 295-309
12. Brosse A.L., Sheets E.S., Lett H.S., and Blumenthal J.A. Exercise and the treatment of clinical depression in adults. Recent findings and future directions. Sports Medicine 32 (2002) 741-760
13. Canli T., and Lesch K.-P. Long story short: the serotonin transporter in emotion regulation and social cognition. Nature Neuroscience 10 (2007) 1103-1109
14. 2 during exercise in humans: the peak vs. maximum issue. Journal of Applied Physiology 95 (2003) 1901-1907
15. Desharnais R., Jobin J., Côté C., Lévesque L., and Godin G. Aerobic exercise and the placebo effect: a controlled study. Psychosomatic Medicine 55 (1993) 149-154
16. Dohm M.R., Hayes J.P., and Garland Jr. T. Quantitative genetics of sprint running speed and swimming endurance in laboratory house mice (Mus domesticus). Evolution 50 (1996) 1688-1701
17. Duman C.H., Schlesinger L., Russell D.S., and Duman R.S. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Research 1199 (2008) 148-158
18. Dunn A.L., Trivedi M.H., Kampert J.B., Clark C.G., and Chambliss H.O. Exercise treatment for depression: efficacy and dose-response. American Journal of Preventive Medicine 28 (2005) 1-8
19. Dunnette M.D. Fads, fashions, and folderol in psychology. American Psychologist 21 (1966) 343-352
20. Ekkekakis P., and Backhouse S.H. Exercise and psychological well-being. In: Maughan R. (Ed). Olympic textbook of science in sport (2009), Wiley-Blackwell, Chichester, United Kingdom 249-269
21. Ekkekakis P., Hall E.E., and Petruzzello S.J. Variation and homogeneity in affective responses to physical activity of varying intensities: an alternative perspective on dose-response based on evolutionary considerations. Journal of Sports Sciences 23 (2005) 477-500
22. Ekkekakis P., Hall E.E., and Petruzzello S.J. Some like it vigorous: individual differences in the preference for and tolerance of exercise intensity. Journal of Sport and Exercise Psychology 27 (2005) 350-374
23. Ekkekakis P., Lind E., Hall E.E., and Petruzzello S.J. Can self-reported tolerance of exercise intensity play a role in exercise testing?. Medicine and Science in Sports and Exercise 39 (2007) 1193-1199
24. Ekkekakis P., Lind E., and Joens-Matre R.R. Can self-reported preference for exercise intensity predict physiologically defined self-selected exercise intensity?. Research Quarterly for Exercise and Sport 77 (2006) 81-90
25. Eysenck H.J. Systematic reviews: meta-analysis and its problems. British Medical Journal 309 (1994) 789-792
26. Eysenck H.J. Meta-analysis or best-evidence synthesis?. Journal of Evaluation in Clinical Practice 1 (1995) 29-36
27. Gershenfeld H.K., Neumann P.E., Mathis C., Crawley J.N., Li X., and Paul S.M. Mapping quantitative trait loci for open-field behavior in mice. Behavior Genetics 27 (1997) 201-210
28. Greenwood B.N., Strong P.V., Brooks L., and Fleshner M. Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise. Psychopharmacology 199 (2008) 209-222
29. Gulati M., Black H.R., Shaw L.J., Arnsdorf M.F., Bairey Merz C.N., Lauer M.S., et al. The prognostic value of a nomogram for exercise capacity in women. New England Journal of Medicine 353 (2005) 468-475
30. Guyatt G.H., Cook D.J., Sackett D.L., Eckman M., and Pauker S. Grades of recommendation for antithrombotic agents. Chest 114 (1988) 441S-444S
31. Hariri A.R., and Holmes A. Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends in Cognitive Sciences 10 (2006) 182-191
32. Hautala A.J., Kiviniemi A.M., Mäkikallio T.H., Kinnunen H., Nissilä S., Huikuri H.V., et al. Individual differences in the responses to endurance and resistance training. European Journal of Applied Physiology 96 (2006) 535-542
33. Jüni P., Altman D.G., and Egger M. Assessing the quality of controlled clinical trials. British Medical Journal 323 (2001) 42-46
34. Kagan J. A trio of concerns. Perspectives on Psychological Science 2 (2007) 361-376
35. King N.A., Hopkins M., Caudwell P., Stubbs R.J., and Blundell J.E. Individual variability following 12 weeks of supervised exercise: identification and characterization of compensation for exercise-induced weight loss. International Journal of Obesity 32 (2008) 177-184
36. Landers D.M., and Arent S.M. Physical activity and mental health. In: Tenenbaum G., and Eklund R.C. (Eds). Handbook of sport psychology. 3rd ed. (2007), Wiley & Sons, New York 469-491
37. Lauderdale D.S., Fabsitz R., Meyer J.M., Sholinsky P., Ramakrishnan V., and Goldberg J. Familial determinants of moderate and intense physical activity: a twin study. Medicine and Science in Sports and Exercise 29 (1997) 1062-1068
38. Lawlor D.A., and Hopker S.W. The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised control trials. British Medical Journal 322 (2001) 1-8
39. Le Galliard J.-F., Clobert J., and Ferrière R. Physical performance and Darwinian fitness in lizards. Nature 432 (2004) 502-505
40. Lightfoot J.T., Turner M.J., Daves M., Vordermark A., and Kleeberger S.R. Genetic influence on daily wheel running activity level. Physiological Genomics 19 (2004) 270-276
41. Lightfoot J.T., Turner M.J., Kleinfehn Knab A., Jedlicka A.E., Oshimura T., Marzec J., et al. Quantitative trait loci associated with maximal exercise endurance in mice. Journal of Applied Physiology 103 (2007) 105-110
42. Lightfoot J.T., Turner M.J., Pomp D., Kleeberger S.R., and Leamy L.J. Quantitative trait loci for physical activity traits in mice. Physiological Genomics 32 (2008) 401-408
43. Lind E., Joens-Matre R.R., and Ekkekakis P. What intensity of physical activity do formerly sedentary middle-aged women select? Evidence of a coherent pattern from physiological, perceptual, and affective markers. Preventive Medicine 40 (2005) 407-419
44. Maia J.A.R., Thomis M., and Beunen G. Genetic factors in physical activity levels: a twin study. American Journal of Preventive Medicine 23 Suppl. 2 (2002) 87-91
45. Mayeda A.R., and Hofstetter J.R. A QTL for the genetic variance in free-running period and level of locomotor activity between inbred strains of mice. Behavior Genetics 29 (1999) 171-176
46. Morgan W.P. Psychological benefits of physical activity. In: Nagle F.J., and Montoye H.J. (Eds). Exercise in health and disease (1981), Charles C. Thomas, Springfield, IL 299-314
47. Morishima-Yamato M., Hisaoka F., Shinomiya S., Harada N., Matoba H., Takahashi A., et al. Cloning and establishment of a line of rats for high levels of voluntary wheel running. Life Sciences 77 (2005) 551-561
48. Munafò M.R., Yalcin B., Willis-Owen S.A., and Flint J. Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data. Biological Psychiatry 63 (2008) 197-206
49. Premack D., and Schaeffer R.W. Some parameters affecting the distributional properties of operant-level running in rats. Journal of the Experimental Analysis of Behavior 6 (1963) 473-475
50. Rezende E.L., Chappell M.A., Gomes F.R., Malisch J.L., and Garland T. Maximal metabolic rates during voluntary exercise, forced exercise, and cold exposure in house mice selectively bred for high wheel-running. Journal of Experimental Biology 208 (2005) 2447-2458
51. Rhodes J.S., Gammie S.C., and Garland T. Neurobiology of mice selected for high voluntary wheel-running activity. Integrative Comparative Biology 45 (2005) 438-455
52. Rhodes J.S., Garland T., and Gammie S.C. Patterns of brain activity associated with variation in voluntary wheel-running behavior. Behavioral Neuroscience 117 (2003) 1243-1256
53. Rhodes R.E., and Smith N.E.I. Personality correlates of physical activity: a review and meta-analysis. British Journal of Sports Medicine 40 (2006) 958-965
54. Roth S.M. Viewpoint: perspective on the future use of genomics in exercise prescription. Journal of Applied Physiology 104 (2008) 1243-1245
55. Salmon P. Effects of physical exercise on anxiety, depression, and sensitivity to stress: a unifying theory. Clinical Psychology Review 21 (2001) 33-61
56. Simonen R.L., Rankinen T., Pérusse L., Leon A.S., Skinner J.S., Wilmore J.H., et al. A dopamine D2 receptor gene polymorphism and physical activity in two family studies. Physiology and Behavior 78 (2003) 751-757
57. Smolka M.N., Bühler M., Schumann G., Klein S., Hu X.-Z., Moayer M., et al. Gene-gene effects on central processing of aversive stimuli. Molecular Psychiatry 12 (2007) 307-317
58. Stathopoulou G., Powers M.B., Berry A.C., Smits A.J., and Otto M.W. Exercise interventions for mental health: a quantitative and qualitative review. Clinical Psychology: Science and Practice 13 (2006) 179-193
59. Sullivan E.L., Koegler F.H., and Cameron J.L. Individual differences in physical activity are closely associated with changes in body weight in adult female rhesus monkeys (Macaca mulatta). American Journal of Physiology 291 (2006) R633-R642
60. Swallow J.G., Carter P.A., and Garland T. Artificial selection for increased wheel-running behavior in house mice. Behavior Genetics 28 (1998) 227-237
61. Van Landuyt L.M., Ekkekakis P., Hall E.E., and Petruzzello S.J. Throwing the mountains into the lakes: on the perils of nomothetic conceptions of the exercise-affect relationship. Journal of Sport and Exercise Psychology 22 (2000) 208-234
62. Wagner P.D. Commentary on viewpoint: perspective on the future use of genomics in exercise prescription. Journal of Applied Physiology 104 (2008) 1246
63. Williams D.M., Dunsiger S., Ciccolo J.T., Lewis B.A., Albrecht A.E., and Marcus B.H. Acute affective response to a moderate-intensity exercise stimulus predicts physical activity participation 6 and 12 months later. Psychology of Sport and Exercise 9 (2008) 231-245
64. Wipfli B.M., Rethorst C.D., and Landers D.M. The anxiolytic effects of exercise: a meta-analysis of randomized trials and dose-response analysis. Journal of Sport and Exercise Psychology 30 (2008) 392-410
65. Wolfarth B., Bray M.S., Hagberg J.M., Perusse L., Rauramaa R., Rivera M.A., et al. The human gene map for performance and health-related fitness phenotypes: the 2004 update. Medicine and Science in Sports and Exercise 37 (2005) 881-903
66. 158met genotype affects μ-opioid neurotransmitter responses to a pain stressor. Science 299 (2003) 1240-1243