In vivo evaluation of the safety of triptolide-loaded hydrogel-thickened microemulsion

Food and Chemical Toxicology

Volumn 46, Issue 12, 2008, Pages 3792-3799

  Xu, Lingyun ^a   Pan, Jinyuan ^b   Chen, Qiyou ^b   Yu, Qizhi ^b   Chen, Huabing ^a   Xu, Huibi ^a   Qiu, Yinsheng ^b   Yang, Xiangliang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Hubei Center for Safety Evaluation of Drugs   (China)

Author keywords

In vivo; Microemulsion; Safety; Transdermal delivery; Triptolide

Indexed keywords

TRIPTOLIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOG; DRUG EFFECT; DRUG FORMULATION; DRUG SAFETY; FEMALE; GUINEA PIG; HYDROGEL; MALE; MICROEMULSION; MOUSE; NONHUMAN; RABBIT; RHEUMATOID ARTHRITIS; SKIN ALLERGY; SKIN IRRITATION; TOXICITY TESTING;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIRHEUMATIC AGENTS; BLOOD CELL COUNT; BLOOD CHEMICAL ANALYSIS; BLOOD PRESSURE; DITERPENES; DOGS; DRUG HYPERSENSITIVITY; EMULSIONS; EPOXY COMPOUNDS; GUINEA PIGS; HYDROGELS; INDICATORS AND REAGENTS; IRRITANTS; MICE; MOTOR ACTIVITY; PHENANTHRENES; RABBITS; SKIN; TISSUE DISTRIBUTION;

ANIMALIA; CANIS FAMILIARIS; CAVIA; MUS; ORYCTOLAGUS CUNICULUS; TRIPTERYGIUM WILFORDII;

EID: 55949107304     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.09.065     Document Type: Article

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