Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 2, 2008, Pages

  Narang, Vishal S ^a   Fraga, Charles ^b   Kumar, Narendra ^a,c   Shen, Jun ^b   Throm, Stacy ^b   Stewart, Clinton F ^b   Waters, Christopher M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Breast cancer resistance protein; Multidrug resistance proteins; Pregnane xenobiotic receptor

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE; GLUCOCORTICOID RECEPTOR; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; PREGNANE XENOBIOTIC RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; 16ALPHA CYANOPREGNENOLONE; ABC TRANSPORTER; ABCC2 PROTEIN, RAT; ABCG2 PROTEIN, RAT; FUMITREMORGIN A; GLUCOCORTICOID; INDENE DERIVATIVE; MIFEPRISTONE; MULTIDRUG RESISTANCE PROTEIN; PREGNANE X RECEPTOR; STEROID RECEPTOR;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TUMOR; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; UPREGULATION; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

RATTUS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; DEXAMETHASONE; ENDOTHELIAL CELLS; GENE EXPRESSION; GLUCOCORTICOIDS; INDENES; MALE; MIFEPRISTONE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PREGNENOLONE CARBONITRILE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 55949099344     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00491.2007     Document Type: Article

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