Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes

Drug Metabolism and Disposition

Volumn 31, Issue 5, 2003, Pages 620-630

  Wang, Hongbing ^a   Faucette, Stephanie R ^a   Gilbert, Darryl ^a   Jolley, Summer L ^a   Sueyoshi, Tatsuya ^b   Negishi, Masahiko ^b   Lecluyse, Edward L ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; CLOTRIMAZOLE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; PHENOBARBITAL; PHENYTOIN; PREGNANE X RECEPTOR; RIFAMPICIN; TESTOSTERONE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

CONFERENCE PAPER; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; GENE EXPRESSION; HEPATOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIVER CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; XENOBIOTIC METABOLISM;

ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CLOTRIMAZOLE; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; HYDROXYLATION; IMMUNOBLOTTING; LIGANDS; OXIDOREDUCTASES, N-DEMETHYLATING; PHENYTOIN; POLYMERASE CHAIN REACTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUCOCORTICOID; RECEPTORS, STEROID; RIFAMPIN; RNA, MESSENGER; TRANSCRIPTION FACTORS;

RODENTIA;

EID: 0037403716     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.5.620     Document Type: Conference Paper

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