Thermotolerant hydrogenases: Biological diversity, properties, and biotechnological applications

Critical Reviews in Microbiology

Volumn 34, Issue 3-4, 2008, Pages 117-130

  Eberly, Jed O ^a   Ely, Roger L ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Bio sensors; Bioremediation; Energy; Feedstocks; Hydrogen; Thermophiles

Indexed keywords

HYDROGEN; HYDROGENASE;

BIODIVERSITY; BIOREMEDIATION; BIOSENSOR; CATALYSIS; DENITRIFICATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEAT TOLERANCE; NITROGEN FIXATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; THERMOPHILIC BACTERIUM; THERMOSTABILITY;

ARCHAEAL PROTEINS; BACTERIAL PROTEINS; ENZYME STABILITY; HOT TEMPERATURE; HYDROGENASE;

BACTERIA (MICROORGANISMS);

EID: 55949091700     PISSN: 1040841X     EISSN: 15497828     Source Type: Journal    
DOI: 10.1080/10408410802240893     Document Type: Review

References (134)

1. Akkerman, I., Janssen, M., Rocha, J., and Wijffels, R. H. 2002. Photobiological hydrogen production: Photochemical efficiency and bioreactor design. Int. J. Hydrogen Energy 27, 1195-1208.
2. Andersson, M., Holmberg, H., and Adlercreutz, P. 1998. Evaluation of alcaligenes eutrophus cells as an nadh regenerating catalyst in organic-aqueous two-phase system. Biotechnol. Bioeng. 57(1), 79-86.
3. Badura, A., Esper, B., Ataka, K., Grunwald, C., Woll, C., Kuhlmann, J., Heberle, J., and Rogner, M. 2006. Light-driven water splitting for (bio-)hydrogen production: Photosystem 2 as the central part of a bioelectrochemical device. Photochem. Photobiol. 82(5), 1385-1390.
4. Baselt, D. R., Fruhberger, B., Klaassen, E., Cemalovic, S., Britton, C. L., Patel, S. V., Mlsna, T. E., McCorkle, D., and Warmack, B. 2003. Design and performance of a microcantilever-based hydrogen sensor. Sens. Actuators B: 88(2), 120-131.
5. Becker, P., Abu-Reesh, I., Markossian, S., Antranikian, G., and Markl, H. 1997. Determination of the kinetic parameters during continuous cultivation of the lipase-producing thermophile bacillus sp. Ihi-91 on olive oil. Appl. Microbiol. Biotechnol. 48(2), 184-190.
6. Beeby, M., O'Connor, B. D., Ryttersgaard, C., Boutz, D. R., Perry, L. J., and Yeates, T. O. 2005. The genomics of disulfide bonding and protein stabilization in thermophiles. Plos. Biol. 3(9), 1549-1558.
7. Benemann, J. R. 1997. Feasibility analysis of photobiological hydrogen production. Int. J. Hydrogen Energy 22(10-11), 979-987.
8. Benemann, J. R. 2000. Hydrogen production by microalgae. J. Appl. Phycol. 12(3-5), 291-300.
9. Blamey, J., Chiong, M., and Smith, E. 2001. Purification and characterization of an iron-nickel hydrogenase from Thermococcus celer. J. Biol. Inorg. Chem. 6, 517-522.
10. Blochl, E., Rachel, R., Burggraf, S., Hafenbradl, D., Jannasch, H. W., and Stetter, K. O. 1997. Pyrolobus fumarii, gen. And sp. Nov., represents a novel group of archaea, extending the upper temperature limit for life to 113 degrees c. Extremophiles 1(1), 14-21.
11. Bonam, D., Lehman, L., Roberts, G. P., and Ludden, P. W. 1989. Regulation of carbon monoxide dehydrogenase and hydrogenase in rhodospirillum rubrum: Effects of co and oxygen on synthesis and activity. J. Bacteriol. 171(6), 3102-3107.
12. Borowitzka, M. A. 1999. Commercial production of microalgae: Ponds, tanks, tubes and fermenters. J. Biotechnol. 70(1-3), 313-321.
13. Brugna-Guiral, M., Tron, P., Nitschke, W., Stetter, K. O., Burlat, B., Guigliarelli, B., Bruschi, M., and Giudici-Orticoni, M. T. 2003. [NiFe] hydrogenases from the hyperthermophilic bacterium aquifex aeolicus: Properties, function, and phylogenetics. Extremophiles 7(2), 145-157.
14. Bruins, M. E., Janssen, A. E. M., and Boom, R. M. 2001. Thermozymes and their applications - a review of recent literature and patents. Appl. Biochem. Biotechnol. 90(2), 155-186.
15. Bryant, F. O. and Adams, M. W. 1989. Characterization of hydrogenase from the hyperthermophilic archaebacterium, pyrococcus furiosus. J. Biol. Chem. 264(9), 5070-5079.
16. Buhrke, T., Lenz, O., Porthun, A., and Friedrich, B. 2004. The h2-sensing complex of ralstonia eutropha: Interaction between a regulatory [nife] hydrogenase and a histidine protein kinase. Molec. Microbiol 51(6), 1677-1689.
17. Carpenter, R. and Mimeault, M. 1987. The photosynthetic partial reactions involved in photoelectrochemical current generation by thylakoid membranes. Biotechnol Lett 9(2), 111-116.
18. Castenholz, R. W. (1988). Thermophilic cyanobacteria: Special problems. In: Methods in enzymology. J. N. Abelson and M. I. Simon (Eds.). Academic Press, Inc., San Diego; 167, 96-100.
19. Chardin, B., Giudici-Orticoni, M. T., De Luca, G., Guigliarelli, B., and Bruschi, M. 2003. Hydrogenases in sulfate-reducing bacteria function as chromium reductase. Appl. Microbiol. Biotechnol. 63(3), 315-321.
20. Chenault, H. and Whitesides, G. 1987. Regeneration of nicotinamide cofactors for use in organic synthesis. Appl. Biochem. Biotechnol. 14(2), 147-197.
21. Cheong, D. and Hansen, C. 2007. Feasibility of hydrogen production in thermophilic mixed fermentation by natural anaerobes. Bioresour. Technol. 98(11), 2229-2239.
22. Cournac, L., Guedeney, G., Peltier, G., and Vignais, P. M. 2004. Sustained photoevolution of molecular hydrogen in a mutant of synechocystis sp. Strain pcc 6803 deficient in the type i nadph-dehydrogenase complex. J. Bacteriol. 186(6), 1737-1746.
23. Davidson, B. H. and Adams, M. 2000. Characterization of chemically modified enzymes for bioremediation reactions, Oak Ridge National Laboratory.
24. Drake, H. 1982. Demostration of hydrogenase in extracts of the homoacetate-fermenting bacterium Clostridium thermoaceticum. J. Bacteriol. 150, 702-709.
25. Drutschmann, M. and Klemme, J. 1985. Sulfide-repressed, membrane-bound hydrogenase in the thermophilic facultative phototroph, chloroflexus aurantiacus. FEMS Microbiol. Lett. 28, 231-235.
26. Dutta, D., De, D., Chaudhuri, S., and Bhattacharya, S. K. 2005. Hydrogen production by cyanobacteria. Microb. Cell Fact. 4, 36.
27. Egorova, K. and Antranikian, G. 2005. Industrial relevance of thermophilic archaea. Curr. Opin. Microbiol. 8(6), 649-655.
28. Esper, B., Badura, A., and Rogner, M. 2006. Photosynthesis as a power supply for (bio-) hydrogen production. Trends Plant Sci 11(11), 543-549.
29. Famiglietti, M., Hochkoeppler, A., and Luisi, L. 1993. Surfactant induced hydrogen production in cyanobacteria. Biotechnol. Bioeng. 42(8), 1014-1018.
30. Fauque, G., Peck, H. D., Moura, J. J. G., Huynh, B. H., Berlier, Y., DerVartanian, D. V., Teixeira, M., Przybyla, A. E., Lespinat, P. A., Moura, I., and LeGall, J. 1988. The three classes of hydrogenases from sulfate-reducing bacteria of the genus desulfovibrio. FEMS Microbiol. Lett. 54(4).
31. 2 in green plants. Nature 143, 204-205.
32. Gaffron, H. 1940. Carbon dioxide reduction with molecular hydrogen in green algae. Am. J. Bot. 27, 273-283.
33. Ghirardi, M. L., Posewitz, M. C., Maness, P. C., Dubini, A., Yu, J., and Seibert, M. 2007. Hydrogenases and hydrogen photoproduction in oxygenic photosynthetic organisms (*). Annu. Rev. Plant Biol. 58, 71-91.
34. Gogotov I., Zorin N., Serebryakova L., and Kondratieva E. 1978. The Properties of Hydrogenase from Thiocapsa roseopersicina. Biochemica. et. Biophysica. Acta. 523, 335-343.
35. Guiral, M., Aubert, C., and Giudici-Orticoni, M. T. 2005. Hydrogen metabolism in the hyperthermophilic bacterium aquifex aeolicus. Biochem. Soc. Trans. 33(Pt 1), 22-24.
36. Haehnel, W. and Hochheimer, A. 1979. On the current generated by a galvanic cell driven by electron transport. Bioelectrochem. Bioener. 6(4), 563-574.
37. Happe, T., Hemschemeier, A., Winkler, M., and Kaminski, A. 2002. Hydrogenases in green algae: Do they save the algae's life and solve our energy problems? Trends Plant Sci. 7(6), 246-250.
38. 2 Activation. J. Mol. Microbiol. Biotechnol. 10, 92-104.
39. Hei, D. J. and Clark, D. S. 1994. Pressure stabilization of proteins from extreme thermophiles. Appl. Environ. Microbiol. 60(3), 932-939.
40. Held, M., Schmid, A., Beilen, J. B. V., and Witholt, B. 2000. Biocatalysis. Biological systems for the production of chemicals. Pure Appl. Chem. 72(7), 1337-1343.
41. Hidalgo, E., Palacios, J. M., Murillo, J., and Ruiz-Argueso, T. 1992. Nucleotide sequence and characterization of four additional genes of the hydrogenase structural operon from rhizobium leguminosarum bv. Viciae. J. Bacteriol. 174(12), 4130-4139.
42. Hoehler, T. M., Albert, D. B., Alperin, M. J., Bebout, B. M., Martens, C. S., and Des Marais, D. J. 2002. Comparative ecology of h2 cycling in sedimentary and phototrophic ecosystems. Antonie. Leeuwenhoek 81(1-4), 575-585.
43. Hoffert, M. I., Caldeira, K., Jain, A. K., Haites, E. F., Harvey, L. D. D., Potter, S. D., Schlesinger, M. E., Schneider, S. H., Watts, R. G., Wigley, T. M. L., and Wuebbles, D. J. 1998. Energy implications of future stabilization of atmospheric co2 content. Nature 395(6705), 881-884.
44. Hummel, W. 1999. Large-scale applications of nad(p)-dependent oxidoreductases: Recent developments. Trends Biotechnol 17(12), 487-492.
45. Ihara, M., Nishihara, H., Yoon, K. S., Lenz, O., Friedrich, B., Nakamoto, H., Kojima, K., Honma, D., Kamachi, T., and Okura, I. 2006. Light-driven hydrogen production by a hybrid complex of a [nife]-hydrogenase and the cyanobacterial photosystem i. Photochem. Photobiol. 82(3), 676-682.
46. Inoue, N., Taira, Y., Emi, T., Yamane, Y., Kashino, Y., Koike, H., and Satoh, K. 2001. Acclimation to the growth temperature and the high-temperature effects on photosystem ii and plasma membranes in a mesophilic cyanobacterium, synechocystis sp. Pcc6803. Plant Cell Physiol. 42(10), 1140-1148.
47. Ishii, M., Takishita, S., Iwasaki, T., Peerapornpisal, Y., Yoshino, J., Kodama, T., and Igarashi, Y. 2000. Purification and Characterization of Membrane-bound Hydrogenase from Hydrogenobacter thermophilus Strain TK-6, an Obligately Autotrophic, Thermophilic, Hydrogen-oxidizing Bacterium Biosci. Biotechnol. Biochem. 64, 492-502
48. Jones, A. K., Lamle, S. E., Pershad, H. R., Vincent, K. A., Albracht, S. P., and Armstrong, F. A. 2003. Enzyme electrokinetics: Electrochemical studies of the anaerobic interconversions between active and inactive states of allochromatium vinosum [nife]-hydrogenase. J. Am. Chem. Soc. 125(28), 8505-8514.
49. Jordan, P., Fromme, P., Witt, H. T., Klukas, O., Saenger, W., and Krauss, N. 2001. Three-dimensional structure of cyanobacterial photosystem i at 2.5 a resolution. Nature 411(6840), 909-917.
50. Juszczak, A., Aono, S., and Adams, M. W. 1991. The extremely thermophilic eubacterium, thermotoga maritima, contains a novel iron-hydrogenase whose cellular activity is dependent upon tungsten. J. Biol. Chem. 266(21), 13834-13841.
51. Kanai, T., Imanaka, H., Nakajima, A., Uwamori, K., Omori, Y., Fukui, T., Atomi, H., and Imanaka, T. 2005. Continuous hydrogen production by the hyperthermophilic archaeon, thermococcus kodakaraensis kod1. J. Biotechnol 116(3), 271-282.
52. Kanai, T., Ito, S., and Imanaka, T. 2003. Characterization of a cytosolic nife-hydrogenase from the hyperthermophilic archaeon Thermococcus kodakaraensis kod1. J. Bacteriol. 185(5), 1705-1711.
53. Kiss, S. S., Bejerano, T.T., and Soares, M.I. 2000. Hydrogen-dependent denitrification: Preliminary assessment of two bio-electrochemical systems. Water Sci. Technol. 42(1-2), 373-379.
54. Klibanov, A. 1983. Biotechnological potential of the enzyme hydrogenase. Process Biochem. 18, 13-16.
55. Konishi, J., Ishii, Y., Onaka, T., Okumura, K., and Suzuki, M. 1997. Thermophilic carbon-sulfur-bond-targeted biodesulfurization. Appl. Environ. Microbiol. 63(8), 3164-3169.
56. Kovacs, K. L., Bagyinka, C., Bodrossy, L., Csaki, R., Fodor, B., Gyorfi, K., Hanczar, T., Kalman, M., Osz, J., Perei, K., Polyak, B., Rakhely, G., Takacs, M., Toth, A., and Tusz, J. 2000. Recent advances in biohydrogen research. Pflugers. Arch. 439(3 Suppl), R81-83.
57. Kovacs, K. L., Kovacs, A. T., Maroti, G., Meszaros, L. S., Balogh, J., Latinovics, D., Fulop, A., David, R., Doroghazi, E., and Rakhely, G. 2005. The hydrogenases of Thiocapsa roseopersicina. Biochem. Soc. T. 33, 61-63.
58. Krahe, M., Antranikian, G., and Markl, H. 1996. Fermentation of extremophilic microorganisms. FEMS Microbiol. Rev. 18(2-3), 271-285.
59. Kumar, S. and Nussinov, R. 2001. How do thermophilic proteins deal with heat? Cell. Mol. Life Sci. 58, 1216-1233.
60. Lamle, S. E., Vincent, K. A., Halliwell, L. M., Albracht, S., and Armstrong, F. A. 2003. Hydrogenase on an electrode: A remarkable heterogeneous catalysis. Dalton Trans., 4152-4157.
61. Lee, K. S., Wu, J. F., Lo, Y. S., Lo, Y. C., Lin, P. J., and Chang, J. S. 2004. Anaerobic hydrogen production with an efficient carrier-induced granular sludge bed bioreactor. Biotechnol. Bioeng. 87(5), 648-657.
62. Lee, M. J. and Zinder, S. H. 1988. Isolation and characterization of a thermophilic bacterium which oxidizes acetate in syntrophic association with a methanogen and which grows acetogenically on h(2)-co(2). Appl. Environ. Microbiol 54(1), 124-129.
63. Leonida, M. 2001. Redox enzymes used in chiral syntheses coupled to coenzyme regeneration. Curr. Med. Chem 8(4), 345-369.
64. Liu, H., Zhang, T., and Fang, H. H. 2003. Thermophilic h2 production from a cellulose-containing wastewater. Biotechnol. Lett. 25(4), 365-369.
65. Lloyd, J. R. 2003. Microbial reduction of metals and radionuclides. FEMS Microbiol. Rev. 27(2-3), 411-425.
66. Lloyd, J. R., Chesnes, J., Glasauer, S., Bunker, D. J., Livens, F. R., and Lovley, D. R. 2002. Reduction of actinides and fission products by fe(iii)-reducing bacteria. Geomicrobiol. J. 19(1), 103-120.
67. Lloyd, J. R., Mabbett, A. N., Williams, D. R., and Macaskie, L. E. 2001. Metal reduction by sulphate-reducing bacteria: Physiological diversity and metal specificity. Hydrometallurgy 59(2-3), 327-337.
68. Lovley, D. R. and Phillips, E. J. P. 1994. Reduction of chromate by desulfovibrio vulgaris and its c3 cytochrome. Appl. Environ. Microbiol. 60(2), 726-728.
69. Lutz, B. J., Fan, Z. H., Burgdorf, T., and Friedrich, B. 2005. Hydrogen sensing by enzyme-catalyzed electrochemical detection. Anal. chem. 77(15), 4969-4975.
70. Ma, K., Weiss, R., and Adams, M. W. 2000. Characterization of hydrogenase ii from the hyperthermophilic archaeon Pyrococcus furiosus and assessment of its role in sulfur reduction. J. Bacteriol. 182(7), 1864-1871.
71. Macaskie, L., Baxter-Plant, V., Creamer, N., Humphries, A., Mikheenko, I., Mikheenko, P., Penfold, D., and Yong, P. 2005. Applications of bacterial hydrogenases in waste decontamination, manufacture of novel bionanocatalysts and in sustainable energy. Biochem. Soc. Trans. 33(Pt 1), 76-79.
72. Madigan, M. T. and Brock, T. D. 1975. Photosynthetic sulfide oxidation by chloroflexus aurantiacus, a filamentous, photosynthetic, gliding bacterium. J. Bacteriol. 122(2), 782-784.
73. Maness, P. C., Smolinski, S., Dillon, A. C., Heben, M. J., and Weaver, P. F. 2002. Characterization of the oxygen tolerance of a hydrogenase linked to a carbon monoxide oxidation pathway in rubrivivax gelatinosus. Appl. Environ. Microbiol. 68(6), 2633-2636.
74. Melis, A. and Happe, T. 2004. Trails of green alga hydrogen research - from Hans Gaffron to new frontiers. Photosynth. Res. 80(1-3), 401-409.
75. Mertens, R., Greiner, L., van den Ban, E. C. D., Haaker, H. B. C. M., and Liese, A. 2003. Practical applications of hydrogenase i from pyrococcus furiosus for nadph generation and regeneration. J. Mol. Catal. B: Enzym. 24-25, 39-52.
76. Mertens, R. and Liese, A. 2004. Biotechnological applications of hydrogenases. Curr. Opin. Biotechnol. 15(4), 343-348.
77. Michel, C., Giudici-Orticoni, M. T., Baymann, F., and Bruschi, M. 2003. Bioremediation of chromate by sulfate-reducing bacteria, cytochromes c3 and hydrogenases. Water, Air and Soil Pollut: Focus 3, 161-169.
78. Mijits, B. N. and Patel, B. K. C. 2001. Random sequence analysis of genomic DNA of an anaerobic, thermophilic, halophilic bacterium, Halothermothrix orenii. Extremophiles 5, 61-69.
79. Miller, J. F., Shah, N. N., Nelson, C. M., Ludlow, J. M., and Clark, D. S. 1988. Pressure and temperature effects on growth and methane production of the extreme thermophile methanococcus jannaschii. Appl. Environ. Microbiol. 54(12), 3039-3042.
80. Miller, S. R., Purugganan, M. D., and Curtis, S. E. 2006. Molecular population genetics and phenotypic diversification of two populations of the thermophilic cyanobacterium mastigocladus laminosus. Appl. Environ. Microbiol. 72(4), 2793-2800.
81. Miyamoto, K., Hallenbeck, P. C., and Benemann, J. R. 1979. Hydrogen production by the thermophilic alga mastigocladus laminosus: Effects of nitrogen, temperature, and inhibition of photosynthesis. Appl. Environ. Microbiol. 38(3), 440-446.
82. Morozov, S. V., Karyakina, E. E., Zorin, N. A., Varfolomeyev, S. D., Cosnier, S., and Karyakin, A. A. 2002. Direct and electrically wired bioelectrocatalysis by hydrogenase from thiocapsa roseopersicina. Bioelectrochem. 55(1-2), 169-171.
83. Mura, G. M., Pedroni, P., Pratesi, C., Galli, G., Serbolisca, L., and Grandi, G. 1996. The [ni-fe] hydrogenase from the thermophilic bacterium acetomicrobium flavidum. Microbiology 142 ( Pt 4), 829-836.
84. Nandi, R. and Sengupta, S. 1998. Microbial production of hydrogen: An overview. Crit. Rev. Microbiol. 24(1), 61-84.
85. Niehaus, F., Bertoldo, C., Kahler, M., and Antranikian, G. 1999. Extremophiles as a source of novel enzymes for industrial application. Appl. Microbiol. Biotechnol. 51(6), 711-729.
86. Nishihara, H., Miyashita, Y., Aoyama, K., Kodama, T., Igarashi, Y., and Takamura, Y. 1997. Characterization of an extremely thermophilic and oxygen-stable membrane-bound hydrogenase from a marine hydrogen-oxidizing bacterium hydrogenovibrio marinus. Biochem. Biophys. Res. Commun. 232(3), 766-770.
87. Nishihara, H., Miyata Y., Miyashita Y., Bernhard M., Pohlmann A., Friedrich B., and Takamura, Y. 2001. Analysis of the Molecular Species of Hydrogenase in the Cells of an Obligately Chemolithoautotrophic, Marine Hydrogen-Oxidizing Bacterium, Hydrogenovibrio marinus. Biosci. Biotechnol. Biochem. 65(12), 178-2784.
88. Odom, J. M. and Peck, H. D. 1981. Hydrogen cycling as a general mechanism for energy coupling in the sulfate-reducing bacteria, desulfovibrio sp. FEMS Microbiol. Lett. 12(1).
89. Pierson, B. K. and Castenholz, R. W. 1974. A phototrophic gliding filamentous bacterium of hot springs, chloroflexus aurantiacus, gen. And sp. Nov. Arch. Microbiol. 100(1), 5-24.
90. Pinto, F., Troshina, O., and Lindblad, P. 2002. A brief look at three decades of research on cyanobacterial hydrogen evolution. Int. J. Hydrogen Energy 27(11-12), 1209-1215.
91. Prince, R. and Kheshgi, H. 2005. The photobiological production of hydrogen: Potential efficiency and effectiveness as a renewable fuel. Crit. Rev. Microbiol. 31(1), 19-31.
92. Rupprecht, J., Hankamer, B., Mussgnug, J. H., Ananyev, G., Dismukes, C., and Kruse, O. 2006. Perspectives and advances of biological h2 production in microorganisms. Appl. Microbiol. Biotechnol. 72(3), 442-449.
93. Sakurai, H. and Masukawa, H. 2007. Promoting r & d in photobiological hydrogen production utilizing mariculture-raised cyanobacteria. Marine. Biotechnol. 9(2), 128-145.
94. Sapra, R., Verhagen, M. F., and Adams, M. W. 2000. Purification and characterization of a membrane-bound hydrogenase from the hyperthermophilic archaeon pyrococcus furiosus. J. Bacteriol. 182(12), 3423-3428.
95. Schicho, R. N., Ma, K., Adams, M. W., and Kelly, R. M. 1993. Bioenergetics of sulfur reduction in the hyperthermophilic archaeon pyrococcus furiosus. J. Bacteriol. 175(6), 1823-1830.
96. Schnackenberg, J., Miyake, M., Miyake, J., Zorin, N. A., and Asada, Y. 1999. In vitro and in vivo coupling of thiocapsa hydrogenase with cyanobacterial and algal electron mediators. J. Biosci. Bioeng. 88(1), 30-34.
97. Schrader, P.S., E.H. Burrows, and R.L. Ely. 2008. High-throughput screening assay for biological hydrogen production. Anal. Chem. 80(11):4014-4019.
98. Schutz, K., Happe, T., Troshina, O., Lindblad, P., Leitao, E., Oliveira, P., and Tamagnini, P. 2004. Cyanobacterial h2 production , a comparative analysis. Planta 218(3), 350-359.
99. Seibert, M., Flynn, T., and Ghirardi, M. L. 2001. Strategies for improving oxygen tolerance of algal hydrogen production. Amsterdam, Pergamon, Elsevier.
100. Sellek, G. A. and Chaudhuri, J. B. 1999. Biocatalysis in organic media using enzymes from extremophiles. Enzyme Microb. Technol. 25(6), 471-482.
101. Selvaggi, A., Tosi, C., Barberini, U., Franchi, E., Rodriguez, F., and Pedroni, P. 1999. In vitro hydrogen photoproduction using Pyrococcus furiosus sulfhydrogenase and tio2. J. Photochem. Photobiol. A: Chem. 125(1-3), 107-112.
102. Shah, N. N. and Clark, D. S. 1990. Partial purification and characterization of two hydrogenases from the extreme thermophile Methanococcus jannaschii. Appl. Environ. Microbiol. 56(4), 858-863.
103. Shima, S. and Thauer, R. K. 2007. A third type of hydrogenase catalyzing h2 activation. Chem. Rec. (New York, N.Y 7(1), 37-46.
104. Silva, P., van den Ban, E., Wassink, H., Haaker, H., de Castro, B., Robb, F., and Hagen, W. 2000 Enzymes of hydrogen metabolism in Pyrococcus furiosus. Eur. J. Biochem. 267, 6541-6551.
105. 2 evolving enzyme complex from Carboxydothermus hydrogenoformans. Eur. J. Biochem. 269, 5712-5721.
106. Soboh, B., Linder, D., and Hedderich, R. 2004. A multisubunit membrane-bound [nife] hydrogenase and an nadh-dependent fe-only hydrogenase in the fermenting bacterium thermoanaerobacter tengcongensis. Microbiology 150(Pt 7), 2451-2463.
107. 2 production by a hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent. Extremophiles 8(4), 317-323.
108. Stephenson, M. and Stickland, L. 1931. Hydrogenase: A bacterial enzyme activating molecular hydrogen: The properties of the enzyme. Biochem. J. 25(1), 205-214.
109. Tamagnini, P., Axelsson, R., Lindberg, P., Oxelfelt, F., Wunschiers, R., and Lindblad, P. 2002. Hydrogenases and hydrogen metabolism of cyanobacteria. Microbiol. Mol. Biol. Rev. 66(1), 1-20.
110. Terlesky Ferry, J. 1988. Ferredoxin requirement for electron transport from the carbon monoxide dehydrogenase complex to a membrane-bound hydrogenase in acetate-grown Methanosarcina thermophila. J. Biol. Chem. 263(9), 4075-4079.
111. Thauer, R. K. 1998. Biochemistry of methanogenesis: A tribute to marjory stephenson. 1998 marjory stephenson prize lecture. Microbiology 144 (Pt 9), 2377-2406.
112. Tiago, I., Teixeira, I., Silva, S., Chung, P., Verissimo, A., and Manaia, C. M. 2004. Metabolic and genetic diversity of mesophilic and thermophilic bacteria isolated from composted municipal sludge on poly-epsilon-caprolactones. Curr. Microbiol. 49(6), 407-414.
113. Turner, P., Mamo, G., and Karlsson, E. N. 2007. Potential and utilization of thermophiles and thermostable enzymes in biorefining. Microb. Cell. Fact. 6, 9.
114. Van der Linden, E., Burgdorf, T., Bernhard, M., Bleijlevens, B., Friedrich, B., and Albracht, S. 2004. The soluble [nife]-hydrogenase from Ralstonia eutropha contains four cyanides in its active site, one of which is responsible for the insensitivity towards oxygen. J. Biol. Inorg. Chem. 9, 616-626.
115. van Haaster, D. J., Hagedoorn, P. L., Jongejan, J. A., and Hagen, W. R. 2005. On the relationship between affinity for molecular hydrogen and the physiological directionality of hydrogenases. Biochem. Soc. T. 33, 12-14.
116. van Niel, E. W. J., Budde, M. A. W., de Haas, G. G., van der Wal, F. J., Claasen, P. A. M., and Stams, A. J. M. 2002. Distinctive properties of high hydrogen producing extreme thermophiles, Caldicellulosiruptor saccharolyticus and Thermotoga elfii. Int. J. Hydrogen Energy 27(11-12), 1391-1398.
117. van Niel, E. W. J., Claassen, P. A. M., and Stams, A. J. M. 2003. Substrate and product inhibition of hydrogen production by the extreme thermophile, caldicellulosiruptor saccharolyticus. Biotechnol. Bioeng. 81(3), 255-262.
118. Van Ooteghem, S. A., Beer, S. K., and Yue, P. C. 2002. Hydrogen production by the thermophilic bacterium thermotoga neapolitana. Appl. Biochem. Biotechnol. 98-100, 177-189.
119. Vargas, M., Kashefi, K., Blunt-Harris, E. L., and Lovley, D. R. 1998. Microbiological evidence for Fe(iii) reduction on early earth. Nature 395(6697), 65-67.
120. Vieille, C., Burdette, D. S., and Zeikus, J. G. 1996. Thermozymes. Biotechnol. Annu. Rev. 2, 1-83.
121. Vieille, C. and Zeikus, G. J. 2001. Hyperthermophilic enzymes: Sources, uses, and molecular mechanisms for thermostability. Microbiol. Mol. Biol. Rev. 65(1), 1-43.
122. Vieille, C. and Zeikus, J. G. 1996. Thermozymes: Identifying molecular determinants of protein structural and functional stability. Trends Biotechnol. 14, 183-190.
123. Vignais, P. and Colbeau, A. 2004. Molecular biology of microbial hydrogenases. Curr. Issues Mol. Biol. 6(2), 159-188.
124. Vignais, P. M., Colbeau, A., Willison, J. C., and Jouanneau, Y. 1985. Hydrogenase, nitrogenase, and hydrogen metabolism in the photosynthetic bacteria. Adv. Microb. Physiol. 26, 155-234.
125. Vignais, P. M., Dimon, B., Zorin, N. A., Tomiyama, M., and Colbeau, A. 2000. Characterization of the hydrogen-deuterium exchange activities of the energy-transducing hupsl hydrogenase and h(2)-signaling hupuv hydrogenase in Rhodobacter capsulatus. J. Bacteriol. 182(21), 5997-6004.
126. Volbeda, A., Charon, M. H., Piras, C., Hatchikian, E. C., Frey, M., and Fontecilla-Camps, J. C. 1995. Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas. Nature 373(6515), 580-587.
127. Woo G., Wasserfallen A., and Wolfe R. 1993. Methyl viologen hydrogenase II, a new member of the hydrogenase family from Methanobacterium thermoautotrophicum delta H. J. Bacteriol. 175, 5970-5977.
128. Woodward, J., Mattingly, S. M., Danson, M., Hough, D., Ward, N., and Adams, M. 1996. In vitro hydrogen production by glucose dehydrogenase and hydrogenase. Nat. Biotechnol. 14(7), 872-874.
129. Woodward, J., Orr, M., Cordray, K., and Greenbaum, E. 2000. Enzymatic production of biohydrogen. Nature 405(6790), 1014-1015.
130. Woolfolk, C. A. and Whiteley, H. R. 1962. Reduction of inorganic compounds with molecular hydrogen by Micrococcus lactilyticus. I. Stoichiometry with compounds of arsenic, selenium, tellurium, transition and other elements. J Bacteriol 84, 647-658.
131. Wraight, C. A. and Clayton, R. K. 1973. The absolute quantum efficiency of bacteriochlorophyll photooxidation in reaction centres of Rhodopdeudomonas sphaeroides. Biochem. Biophys. Acta 333, 246-260.
132. Yanke, L. J., Bryant, R. D., and Laishley, E. J. 1995. Hydrogenase I of Clostridium pasteurianum functions as a novel selenite reductase. Anaerobe 1(1), 61-67.
133. Yaropolov, A., Malovik, V., Izumarudov, V., Zorin, N., Bachurin, S., Gogotov, I., and Varfolomeev, S. 1982 Immobilization of hydrogenase in semi-conductor gels and its use in the electrooxidation of hydrogen at the anode of a biofuel cell. Applied Biochemistry and Microbiology vol. 18(4) 515-524
134. Yokoyama, H., Waki, M., Moriya, N., Yasuda, T., Tanaka, Y., and Haga, K. 2007. Effect of fermentation temperature on hydrogen production from cow waste slurry by using anaerobic microflora within the slurry. Appl. Microbiol. Biotechnol. 74(2), 474-483.