Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate

Proteins: Structure, Function and Genetics

Volumn 32, Issue 4, 1998, Pages 515-522

  Transue, Thomas R ^a,b   De Genst, Erwin ^a   Ghahroudi, Mehdi Arbabi ^a   Wyns, Lode ^a   Muyldermans, Serge ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b NONE   (Belgium)

Author keywords

Acetamido group; CDR loop; Heavy chain immunoglobulin; Inhibition; Lysozyme; Mimicry; Solvent accessible surface area; Sugar; V(H)H

Indexed keywords

ACETAMIDE; CARBOHYDRATE; IMMUNOGLOBULIN HEAVY CHAIN; LYSOZYME; SOLVENT; SUGAR;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVE SITE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; MICROCOCCUS LUTEUS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CAMELS; CARBOHYDRATE CONFORMATION; CARBOHYDRATES; ENZYME INHIBITORS; IMMUNOGLOBULIN HEAVY CHAINS; LYSINE; MICROCOCCUS; MODELS, MOLECULAR; MOLECULAR MIMICRY;

CAMELIDAE; MICROCOCCUS LUTEUS;

EID: 0031855323     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19980901)32:4<515::AID-PROT9>3.0.CO;2-E     Document Type: Article

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