메뉴 건너뛰기




Volumn 2, Issue 2, 2008, Pages 92-101

New strategies for allergen immunotherapy

Author keywords

Allergen immunotherapy; Allergen CpG fusion; Allergen fusion proteins; Allergoids; Anti IgE; Depigmented allergen extracts; MPL; Peptides; Recombinant allergens; Sublingual immunotheraphy

Indexed keywords

ALLERGEN; ALLERGOID; ALUMINUM HYDROXIDE; COLECALCIFEROL; DNA VACCINE; FREUND ADJUVANT; GAMMA INTERFERON; HISTAMINE; HYBRID PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 5; LIPOPOLYSACCHARIDE; LIPOSOME; OMALIZUMAB; PEPTIDE DERIVATIVE; PHOSPHORYL LIPID A; PLACEBO; POLLINEX QUATTRO; RECOMBINANT ALLERGEN; RECOMBINANT BET V; SAPONIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCINE;

EID: 55849083558     PISSN: 1872213X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221308784543610     Document Type: Review
Times cited : (18)

References (83)
  • 1
    • 0035804276 scopus 로고    scopus 로고
    • Allergy and allergic diseases. First of two parts
    • Kay AB. Allergy and allergic diseases. First of two parts. N Engl J Med 2001; 344(1): 30-37.
    • (2001) N Engl J Med , vol.344 , Issue.1 , pp. 30-37
    • Kay, A.B.1
  • 2
    • 0035843316 scopus 로고    scopus 로고
    • Allergy and allergic diseases. Second of two parts
    • Kay AB. Allergy and allergic diseases. Second of two parts. N Engl J Med 2001; 344(2): 109-113.
    • (2001) N Engl J Med , vol.344 , Issue.2 , pp. 109-113
    • Kay, A.B.1
  • 3
    • 1342308180 scopus 로고    scopus 로고
    • Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
    • Ling EM, Smith T, Nguyen XD, et al. Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004; 363: 608-615.
    • (2004) Lancet , vol.363 , pp. 608-615
    • Ling, E.M.1    Smith, T.2    Nguyen, X.D.3
  • 4
    • 0002430744 scopus 로고    scopus 로고
    • World Health Organization Position Paper. Allergen immunotherapy: Therapeutical vaccines for allergic diseases
    • Bousquet J, Lockey R, Malling HJ. World Health Organization Position Paper. Allergen immunotherapy: therapeutical vaccines for allergic diseases. Allergy 1998; 53 (54): S3-S4.
    • (1998) Allergy , vol.53 , Issue.54
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 5
    • 34047179902 scopus 로고    scopus 로고
    • Allergen immunotherapy: Where is it now?
    • Nelson HS. Allergen immunotherapy: Where is it now? J Allergy Clin Immunol 2007; 119: 769-777.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 769-777
    • Nelson, H.S.1
  • 6
    • 0027733605 scopus 로고
    • Nonfatal systemic allergic reactions induced by skin testing and immunotherapy
    • Lin MS, Tanner E, Lynn J, Friday GA Jr. Nonfatal systemic allergic reactions induced by skin testing and immunotherapy. Ann Allergy 1993; 71: 557-562.
    • (1993) Ann Allergy , vol.71 , pp. 557-562
    • Lin, M.S.1    Tanner, E.2    Lynn, J.3    Friday Jr., G.A.4
  • 7
    • 0028816435 scopus 로고
    • Immunotherapy: A one year prospective study to evaluate risk factors of systemic reactions
    • Tinkelman DG, Cole WO III, Tunno J. Immunotherapy: a one year prospective study to evaluate risk factors of systemic reactions. J Allergy Clin Immunol 1995; 95: 8-14.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 8-14
    • Tinkelman, D.G.1    Cole III, W.O.2    Tunno, J.3
  • 8
    • 31944443997 scopus 로고    scopus 로고
    • Frew AJ, Powell RJ, Corrigan CJ, Durham SR. UK Immunotherapy Study Group Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2006; 117(2): 319-325
    • Frew AJ, Powell RJ, Corrigan CJ, Durham SR. UK Immunotherapy Study Group Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2006; 117(2): 319-325
  • 9
    • 84973587700 scopus 로고
    • CSM update: Desensitization vaccines
    • Committee of the Safety of Medicines
    • Committee of the Safety of Medicines. CSM update: desensitization vaccines. Br Med J 1986; 292: 293: 948.
    • (1986) Br Med J , vol.292 , Issue.293 , pp. 948
  • 10
    • 34047163404 scopus 로고    scopus 로고
    • Mechanisms of allergen immunotherapy
    • Akdis M, Akdis CA. Mechanisms of allergen immunotherapy. J Allergy Clin Immunol 2007; 119: 780-789.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 780-789
    • Akdis, M.1    Akdis, C.A.2
  • 11
    • 15244344608 scopus 로고    scopus 로고
    • Robinson DS, Larch M, Durham SR. Tregs and allergic disease. J Clin Invest 2004; 114(10): 1389-11397.
    • Robinson DS, Larch M, Durham SR. Tregs and allergic disease. J Clin Invest 2004; 114(10): 1389-11397.
  • 12
    • 35048822971 scopus 로고    scopus 로고
    • Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis
    • Wine Y, Cohen-Hadar N, Freeman A, Frolow F. Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis. Biotechnol Bioeng 2007; 98(3): 711-718.
    • (2007) Biotechnol Bioeng , vol.98 , Issue.3 , pp. 711-718
    • Wine, Y.1    Cohen-Hadar, N.2    Freeman, A.3    Frolow, F.4
  • 13
    • 0042510918 scopus 로고    scopus 로고
    • Immunotherapy with a depigmented, polymerized vaccine of Olea europaea pollen allergens significantly reduces specific bronchial and skin test reactivity in sensitized patients after one year of treatment
    • Guerra F, Daza JC, Almeda E. Immunotherapy with a depigmented, polymerized vaccine of Olea europaea pollen allergens significantly reduces specific bronchial and skin test reactivity in sensitized patients after one year of treatment. J Investig Allergol Clin Immunol 2003; 13: 108-117.
    • (2003) J Investig Allergol Clin Immunol , vol.13 , pp. 108-117
    • Guerra, F.1    Daza, J.C.2    Almeda, E.3
  • 15
    • 33745219481 scopus 로고    scopus 로고
    • Significant improvement of specific bronchial hyperreactivity in asthmatic children after 4 months of treatment with a modified extract of dermatophagoides pteronyssinus
    • Ibero M, Castillo MJ. Significant improvement of specific bronchial hyperreactivity in asthmatic children after 4 months of treatment with a modified extract of dermatophagoides pteronyssinus. J Investig Allergol Clin Immunol 2006; 16(3): 194-202.
    • (2006) J Investig Allergol Clin Immunol , vol.16 , Issue.3 , pp. 194-202
    • Ibero, M.1    Castillo, M.J.2
  • 16
    • 0742305788 scopus 로고    scopus 로고
    • Significant improvement in symptoms, skin test, and specific bronchial reactivity after 6 months of treatment with a depigmented, polymerized extract of Dermatophagoides pteronyssinus and D. farinae
    • Ferrer A, Garcia-Sellos J. Significant improvement in symptoms, skin test, and specific bronchial reactivity after 6 months of treatment with a depigmented, polymerized extract of Dermatophagoides pteronyssinus and D. farinae. J Investig Allergy Clin Immunol 2003; 13(4): 244-251.
    • (2003) J Investig Allergy Clin Immunol , vol.13 , Issue.4 , pp. 244-251
    • Ferrer, A.1    Garcia-Sellos, J.2
  • 17
    • 0034110867 scopus 로고    scopus 로고
    • Mechanisms of allergen-specific immunotherapy
    • Akdis CA, Blaser K. Mechanisms of allergen-specific immunotherapy. Allergy 2000; 55(6): 522-530.
    • (2000) Allergy , vol.55 , Issue.6 , pp. 522-530
    • Akdis, C.A.1    Blaser, K.2
  • 18
    • 0027467542 scopus 로고
    • A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: Clinical efficacy and side effects
    • Haugaard L, Dahl R, Jacobsen L. A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: clinical efficacy and side effects. J Allergy Clin Immunol 1993; 91(3): 709-722.
    • (1993) J Allergy Clin Immunol , vol.91 , Issue.3 , pp. 709-722
    • Haugaard, L.1    Dahl, R.2    Jacobsen, L.3
  • 19
    • 23044463781 scopus 로고    scopus 로고
    • Comparative study of tolerance between unmodified and high doses of chemically modified allergen vaccines of Dermatophagoides pteronyssinus
    • Casanovas M, Fernandez-Caldas E, Alamar R, Basomba A. Comparative study of tolerance between unmodified and high doses of chemically modified allergen vaccines of Dermatophagoides pteronyssinus. Int Arch Allergy Immunol 2005; 137(3): 211-218.
    • (2005) Int Arch Allergy Immunol , vol.137 , Issue.3 , pp. 211-218
    • Casanovas, M.1    Fernandez-Caldas, E.2    Alamar, R.3    Basomba, A.4
  • 20
    • 55849085256 scopus 로고    scopus 로고
    • Berrens, L.: WO9406821 (1994).
    • Berrens, L.: WO9406821 (1994).
  • 21
    • 20044365298 scopus 로고    scopus 로고
    • Alvarez-Cuesta E, Aragoneses-Gilsanz E, Martin-Garcia C, Berges-Gimeno P, Gonzalez-Mancebo E, Cuesta-Herranz J. Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life. Clin Exp Allergy 2005; 35(5): 572-578. Erratum in: Clin Exp Allergy 2005; 35(11): 1504.
    • Alvarez-Cuesta E, Aragoneses-Gilsanz E, Martin-Garcia C, Berges-Gimeno P, Gonzalez-Mancebo E, Cuesta-Herranz J. Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life. Clin Exp Allergy 2005; 35(5): 572-578. Erratum in: Clin Exp Allergy 2005; 35(11): 1504.
  • 22
    • 33750503811 scopus 로고    scopus 로고
    • Successful management of mite-allergic asthma with modified extracts of Dermatophagoides pteronyssinus and Dermatophagoides farinae in a double-blind, placebo-controlled study
    • García-Robaina JC, Sánchez I, de la Torre F, Fernández-Caldas E, Casanovas M. Successful management of mite-allergic asthma with modified extracts of Dermatophagoides pteronyssinus and Dermatophagoides farinae in a double-blind, placebo-controlled study. J Allergy Clin Immunol 2006; 118(5): 1026-1032.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.5 , pp. 1026-1032
    • García-Robaina, J.C.1    Sánchez, I.2    de la Torre, F.3    Fernández-Caldas, E.4    Casanovas, M.5
  • 23
    • 33646934368 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule
    • Colás C, Monzón S, Venturini M, Lezaun A. Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule. J Allergy Clin Immunol 2006; 117(4): 810-816.
    • (2006) J Allergy Clin Immunol , vol.117 , Issue.4 , pp. 810-816
    • Colás, C.1    Monzón, S.2    Venturini, M.3    Lezaun, A.4
  • 25
    • 34047164918 scopus 로고    scopus 로고
    • Sublingual immunotherapy: The optimism and the issues
    • Pajno GB. Sublingual immunotherapy: the optimism and the issues. J Allergy Clin Immunol 2007; 119: 796-801.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 796-801
    • Pajno, G.B.1
  • 26
    • 12444291506 scopus 로고    scopus 로고
    • Sublingual immunotherapy for allergic rhinitis: A systematic review and meta-analysis
    • Wilson DR, Torres LM, Durham SR. Sublingual immunotherapy for allergic rhinitis: a systematic review and meta-analysis. Allergy 2005; 60: 4-12.
    • (2005) Allergy , vol.60 , pp. 4-12
    • Wilson, D.R.1    Torres, L.M.2    Durham, S.R.3
  • 27
    • 33748289993 scopus 로고    scopus 로고
    • Efficacy of sublingual immunotherapy in asthma: Systematic review of randomized-clinical trials using the Cochrane collaboration method
    • Calamita Z, Saconato H. Pela AB, Atallah AN. Efficacy of sublingual immunotherapy in asthma: systematic review of randomized-clinical trials using the Cochrane collaboration method. Allergy 2006; 61: 1162-1172.
    • (2006) Allergy , vol.61 , pp. 1162-1172
    • Calamita, Z.1    Saconato, H.2    Pela, A.B.3    Atallah, A.N.4
  • 28
    • 34250836330 scopus 로고    scopus 로고
    • Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: A randomized, double-blind, placebo-controlled study
    • Pajno GB, Caminiti L, Vita D, et al. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol 2007; 120(1): 164-170.
    • (2007) J Allergy Clin Immunol , vol.120 , Issue.1 , pp. 164-170
    • Pajno, G.B.1    Caminiti, L.2    Vita, D.3
  • 29
    • 27644459770 scopus 로고    scopus 로고
    • Sublingual immunotherapy for hazelnut food allergy: A randomized, double-blind, placebo-controlled study with a standardized hazelnut extract
    • Enrique E, Pineda F, Malek T, et al. Sublingual immunotherapy for hazelnut food allergy: a randomized, double-blind, placebo-controlled study with a standardized hazelnut extract. J Allergy Clin Immunol 2005; 116(5): 1073-1079.
    • (2005) J Allergy Clin Immunol , vol.116 , Issue.5 , pp. 1073-1079
    • Enrique, E.1    Pineda, F.2    Malek, T.3
  • 30
    • 0842308886 scopus 로고    scopus 로고
    • Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: A randomized, placebo-controlled, double-blind, double-dummy study
    • Hansen KS, Khinchi MS, Skov PS, Bindslev-Jensen C, Poulsen LK, Malling HJ. Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: a randomized, placebo-controlled, double-blind, double-dummy study. Allergy 2004; 59(1): 45-53.
    • (2004) Allergy , vol.59 , Issue.1 , pp. 45-53
    • Hansen, K.S.1    Khinchi, M.S.2    Skov, P.S.3    Bindslev-Jensen, C.4    Poulsen, L.K.5    Malling, H.J.6
  • 31
    • 0032574206 scopus 로고    scopus 로고
    • Randomised controlled trial of local allergoid immunotherapy on allergic inflammation in mite-induced rhinoconjunctivitis
    • Passalacqua G, Albano M, Fregonese L, et al. Randomised controlled trial of local allergoid immunotherapy on allergic inflammation in mite-induced rhinoconjunctivitis. Lancet 1998; 351(9103): 629-632.
    • (1998) Lancet , vol.351 , Issue.9103 , pp. 629-632
    • Passalacqua, G.1    Albano, M.2    Fregonese, L.3
  • 32
    • 42249088234 scopus 로고    scopus 로고
    • Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
    • Kool M, Soullie T, van Nimwegen M, et al. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med 2008;
    • (2008) J Exp Med
    • Kool, M.1    Soullie, T.2    van Nimwegen, M.3
  • 33
    • 4544370248 scopus 로고    scopus 로고
    • Aluminium hydroxide down-regulates T helper 2 responses by allergen-stimulated human peripheral blood mononuclear cells
    • Wilcock LK, Francis JN, Durham SR. Aluminium hydroxide down-regulates T helper 2 responses by allergen-stimulated human peripheral blood mononuclear cells. Clin Exp Allergy 2004; 34(9): 1373-1378.
    • (2004) Clin Exp Allergy , vol.34 , Issue.9 , pp. 1373-1378
    • Wilcock, L.K.1    Francis, J.N.2    Durham, S.R.3
  • 34
    • 0034995781 scopus 로고    scopus 로고
    • A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections
    • Drachenberg KJ, Wheeler AW, Stuebner P, Horak F. A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections. Allergy 2001; 56(6): 498-505.
    • (2001) Allergy , vol.56 , Issue.6 , pp. 498-505
    • Drachenberg, K.J.1    Wheeler, A.W.2    Stuebner, P.3    Horak, F.4
  • 35
    • 38949193498 scopus 로고    scopus 로고
    • The CREATE project: Development of certified reference materials for allergenic products and validation of methods for their quantification
    • van Ree R, Chapman MD, Ferreira F, et al. The CREATE project: development of certified reference materials for allergenic products and validation of methods for their quantification. Allergy 2008; 63(3): 310-326.
    • (2008) Allergy , vol.63 , Issue.3 , pp. 310-326
    • van Ree, R.1    Chapman, M.D.2    Ferreira, F.3
  • 36
    • 33745649409 scopus 로고    scopus 로고
    • The chitinase allergens Der p 15 and Der p 18 from Dermatophagoides pteronyssinus
    • O'Neil SE, Heinrich TK, Hales BJ, et al. The chitinase allergens Der p 15 and Der p 18 from Dermatophagoides pteronyssinus. Clin Exp Allergy 2006; 36(6): 831-839.
    • (2006) Clin Exp Allergy , vol.36 , Issue.6 , pp. 831-839
    • O'Neil, S.E.1    Heinrich, T.K.2    Hales, B.J.3
  • 39
    • 55849091586 scopus 로고    scopus 로고
    • Pauli G, Malling H, Rak S, et al. Clinical efficacy of subcutaneous immunotherapy in birch pollen allergic patients: a randomized-double-blind placebo controlled study ith recomninant Bet v 1 versus natural Bet v 1 or standardized birch extract. In: Valenta R, Akdis C, Bohle B, ed., 25th Congress of the European Academy of Allergology and Clinical Immunology 2006; 28 [Abstract 83]
    • Pauli G, Malling H, Rak S, et al. Clinical efficacy of subcutaneous immunotherapy in birch pollen allergic patients: a randomized-double-blind placebo controlled study ith recomninant Bet v 1 versus natural Bet v 1 or standardized birch extract. In: Valenta R, Akdis C, Bohle B, ed., 25th Congress of the European Academy of Allergology and Clinical Immunology 2006; 28 [Abstract 83]
  • 41
    • 5144222703 scopus 로고    scopus 로고
    • Vaccination with genetically engineered allergens prevents progression of allergic disease
    • Niederberger V, Horak F, Vrtala S, et al. Vaccination with genetically engineered allergens prevents progression of allergic disease. Proc Natl Acad Sci USA 2004; 101 (2): 14677-14682.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.2 , pp. 14677-14682
    • Niederberger, V.1    Horak, F.2    Vrtala, S.3
  • 42
    • 34047180982 scopus 로고    scopus 로고
    • Update on the current status of peptide immunotherapy
    • Larché M. Update on the current status of peptide immunotherapy. J Allergy Clin Immunol 2007; 119: 906-909.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 906-909
    • Larché, M.1
  • 43
  • 45
    • 0033591638 scopus 로고    scopus 로고
    • Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions
    • Haselden BM, Kay AB, Larché M. Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions. J Exp Med 1999; 189(12): 1885-1894.
    • (1999) J Exp Med , vol.189 , Issue.12 , pp. 1885-1894
    • Haselden, B.M.1    Kay, A.B.2    Larché, M.3
  • 46
    • 0035423535 scopus 로고    scopus 로고
    • Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects
    • Oldfield WL, Kay AB, Larche M. Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects. J Immunol 2001; 167(3): 1734-1739.
    • (2001) J Immunol , vol.167 , Issue.3 , pp. 1734-1739
    • Oldfield, W.L.1    Kay, A.B.2    Larche, M.3
  • 47
    • 0037031090 scopus 로고    scopus 로고
    • Effect of T-cell peptides derived from Feld1 on allergic reactions and cytokine production in patients sensitive to cats: A randomised controlled trial
    • Oldfield WL, Kay AB, Larché M. Effect of T-cell peptides derived from Feld1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial. Lancet 2002; 360(9326): 47-53.
    • (2002) Lancet , vol.360 , Issue.9326 , pp. 47-53
    • Oldfield, W.L.1    Kay, A.B.2    Larché, M.3
  • 48
    • 0031866059 scopus 로고    scopus 로고
    • Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom
    • Müller U, Akdis CA, Fricker M, et al. Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom. J Allergy Clin Immunol 1998; 101: 747-754.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 747-754
    • Müller, U.1    Akdis, C.A.2    Fricker, M.3
  • 49
    • 0037395291 scopus 로고    scopus 로고
    • Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: Results of a phase I trial
    • Fellrath JM, Kettner A, Dufour N, et al. Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: results of a phase I trial. J Allergy Clin Immunol 2003; 111(4): 854-861.
    • (2003) J Allergy Clin Immunol , vol.111 , Issue.4 , pp. 854-861
    • Fellrath, J.M.1    Kettner, A.2    Dufour, N.3
  • 50
    • 33645301858 scopus 로고    scopus 로고
    • Induction of interleukin-10 and suppressor of cytokine signaling-3 gene expression following peptide immunotherapy
    • Tarzi M, Klunker S, Texier C, Verhoef A, et al. Induction of interleukin-10 and suppressor of cytokine signaling-3 gene expression following peptide immunotherapy. Clin Exp Allergy 2006; 36(4): 465-474.
    • (2006) Clin Exp Allergy , vol.36 , Issue.4 , pp. 465-474
    • Tarzi, M.1    Klunker, S.2    Texier, C.3    Verhoef, A.4
  • 51
    • 38949201705 scopus 로고    scopus 로고
    • Immunomodulators for allergic respiratory disorders
    • Casale TB, Stokes JR. Immunomodulators for allergic respiratory disorders. J Allergy Clin Immunol 2008; 121(2): 288-296.
    • (2008) J Allergy Clin Immunol , vol.121 , Issue.2 , pp. 288-296
    • Casale, T.B.1    Stokes, J.R.2
  • 52
    • 0036174045 scopus 로고    scopus 로고
    • Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis
    • Kuehr J, Brauburger J, Zielen S, et al. Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis. J Allergy Clin Immunol 2002; 109(2): 274-280.
    • (2002) J Allergy Clin Immunol , vol.109 , Issue.2 , pp. 274-280
    • Kuehr, J.1    Brauburger, J.2    Zielen, S.3
  • 53
    • 29544443510 scopus 로고    scopus 로고
    • Immune Tolerance Network Group Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis
    • Casale TB, Busse WW, Kline JN, et al. Immune Tolerance Network Group Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. J Allergy Clin Immunol 2006; 117(1): 134-140.
    • (2006) J Allergy Clin Immunol , vol.117 , Issue.1 , pp. 134-140
    • Casale, T.B.1    Busse, W.W.2    Kline, J.N.3
  • 54
    • 0036964533 scopus 로고    scopus 로고
    • Allergen-immunostimulatory oligodeoxynucleotide conjugate: A novel allergoid for immunotherapy
    • Spiegelberg HL, Horner AA, Takabayashi K, Raz E. Allergen-immunostimulatory oligodeoxynucleotide conjugate: a novel allergoid for immunotherapy. Curr Opin Allergy Clin Immunol 2002; 2(6): 547-551.
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , Issue.6 , pp. 547-551
    • Spiegelberg, H.L.1    Horner, A.A.2    Takabayashi, K.3    Raz, E.4
  • 56
    • 0343953087 scopus 로고    scopus 로고
    • Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity
    • Tighe H, Takabayashi K, Schwartz D, et al. Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity. J Allergy Clin Immunol 2000; 106: 124-134.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 124-134
    • Tighe, H.1    Takabayashi, K.2    Schwartz, D.3
  • 57
    • 33749436870 scopus 로고    scopus 로고
    • Immune Tolerance Network Group. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis
    • Creticos PS, Schroeder JT, Hamilton RG, et al. Immune Tolerance Network Group. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 2006; 355(14): 1445-1455.
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1445-1455
    • Creticos, P.S.1    Schroeder, J.T.2    Hamilton, R.G.3
  • 58
    • 34047111006 scopus 로고    scopus 로고
    • Phase 2/3 study of the novel vaccine Amb a 1 immunostimulatory oligodeoxyribonucleoside conjugate AIC in ragweed allergic adults [abstract]
    • Busse W, Gross G, Korenblat P, et al. Phase 2/3 study of the novel vaccine Amb a 1 immunostimulatory oligodeoxyribonucleoside conjugate AIC in ragweed allergic adults [abstract]. J Allergy Clin Immunol 2006; 117: S88-S889.
    • (2006) J Allergy Clin Immunol , vol.117
    • Busse, W.1    Gross, G.2    Korenblat, P.3
  • 59
    • 0036283309 scopus 로고    scopus 로고
    • Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus: A randomized, double-blind, placebo-controlled trial in asthmatic patients
    • Basomba A, Tabar AI, de Rojas DH, et al. Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus: a randomized, double-blind, placebo-controlled trial in asthmatic patients. J Allergy Clin Immunol 2002; 109(6): 943-948.
    • (2002) J Allergy Clin Immunol , vol.109 , Issue.6 , pp. 943-948
    • Basomba, A.1    Tabar, A.I.2    de Rojas, D.H.3
  • 60
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
    • Roy K, Mao HQ, Huang SK, Leong KW. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med 1999; 5(4): 387-391.
    • (1999) Nat Med , vol.5 , Issue.4 , pp. 387-391
    • Roy, K.1    Mao, H.Q.2    Huang, S.K.3    Leong, K.W.4
  • 61
    • 33745370080 scopus 로고    scopus 로고
    • Generation of hypoallergenic DNA vaccines by forced ubiquitination: Preventive and therapeutic effects in a mouse model of allergy
    • Bauer R, Scheiblhofer S, Kern K, et al. Generation of hypoallergenic DNA vaccines by forced ubiquitination: preventive and therapeutic effects in a mouse model of allergy. J Allergy Clin Immunol 2006; 118(1): 269-276.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.1 , pp. 269-276
    • Bauer, R.1    Scheiblhofer, S.2    Kern, K.3
  • 62
    • 33748088980 scopus 로고    scopus 로고
    • Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization
    • Gabler M, Scheiblhofer S, Kern K, et al. Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization. J Allergy Clin Immunol 2006; 118(3): 734-741.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.3 , pp. 734-741
    • Gabler, M.1    Scheiblhofer, S.2    Kern, K.3
  • 63
    • 4344605211 scopus 로고    scopus 로고
    • Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein
    • Zhang K, Kepley CL, Terada T, Zhu D, Perez H, Saxon A. Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein. J Allergy Clin Immunol 2004; 114(2): 321-327.
    • (2004) J Allergy Clin Immunol , vol.114 , Issue.2 , pp. 321-327
    • Zhang, K.1    Kepley, C.L.2    Terada, T.3    Zhu, D.4    Perez, H.5    Saxon, A.6
  • 64
    • 17644388057 scopus 로고    scopus 로고
    • A chimeric human-cat fusion protein blocks cat-induced allergy
    • Zhu D, Kepley CL, Zhang K, Terada T, Yamada T, Saxon A. A chimeric human-cat fusion protein blocks cat-induced allergy. Nat Med 2005; 11(4): 446-449.
    • (2005) Nat Med , vol.11 , Issue.4 , pp. 446-449
    • Zhu, D.1    Kepley, C.L.2    Zhang, K.3    Terada, T.4    Yamada, T.5    Saxon, A.6
  • 65
    • 34548693921 scopus 로고    scopus 로고
    • Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation
    • Razafindratsita A, Saint-Lu N, Mascarell L, et al. Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation. J Allergy Clin Immunol 2007; 120(2): 278-285.
    • (2007) J Allergy Clin Immunol , vol.120 , Issue.2 , pp. 278-285
    • Razafindratsita, A.1    Saint-Lu, N.2    Mascarell, L.3
  • 66
    • 0032185775 scopus 로고    scopus 로고
    • Allergen immunotherapy inhibits airway eosinophilia and hyperresponsiveness associated with decreased IL-4 production by lymphocytes in a murine model of allergic asthma
    • Van Oosterhout AJ, Van Esch B, Hofman G, et al. Allergen immunotherapy inhibits airway eosinophilia and hyperresponsiveness associated with decreased IL-4 production by lymphocytes in a murine model of allergic asthma. Am J Respir Cell Mol Biol 1998; 19(4): 622-628.
    • (1998) Am J Respir Cell Mol Biol , vol.19 , Issue.4 , pp. 622-628
    • Van Oosterhout, A.J.1    Van Esch, B.2    Hofman, G.3
  • 68
    • 0037018104 scopus 로고    scopus 로고
    • in vitro Generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, et al. in vitro Generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines. J Exp Med 2002; 195(5): 603-616.
    • (2002) J Exp Med , vol.195 , Issue.5 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 69
    • 36749096949 scopus 로고    scopus 로고
    • IL-10-inducing adjuvants enhance sublingual immunotherapy efficacy in a murine asthma model
    • Van Overtvelt L, Lombardi V, Razafindratsita A, et al. IL-10-inducing adjuvants enhance sublingual immunotherapy efficacy in a murine asthma model. Int Arch Allergy Immunol 2008; 145(2): 152-162.
    • (2008) Int Arch Allergy Immunol , vol.145 , Issue.2 , pp. 152-162
    • Van Overtvelt, L.1    Lombardi, V.2    Razafindratsita, A.3
  • 70
    • 0034820286 scopus 로고    scopus 로고
    • IFN-gamma and IL-12 plasmid DNAs as vaccine adjuvant in a murine model of grass allergy
    • Kumar M, Behera AK, Hu J, Lockey RF, Mohapatra SS. IFN-gamma and IL-12 plasmid DNAs as vaccine adjuvant in a murine model of grass allergy. J Allergy Clin Immunol 2001; 108(3): 402-408.
    • (2001) J Allergy Clin Immunol , vol.108 , Issue.3 , pp. 402-408
    • Kumar, M.1    Behera, A.K.2    Hu, J.3    Lockey, R.F.4    Mohapatra, S.S.5
  • 72
    • 33646190155 scopus 로고    scopus 로고
    • Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy
    • Johansen P, Senti GJ. Martinez GJM, et al. Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin Exp Allergy 2005; 35: 1591-1598.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1591-1598
    • Johansen, P.1    Senti, G.J.2    Martinez, G.J.M.3
  • 75
    • 55849118658 scopus 로고    scopus 로고
    • US20070190069
    • Koppelman, S.J.: US20070190069 (2007).
    • (2007)
    • Koppelman, S.J.1
  • 81
    • 0034847103 scopus 로고    scopus 로고
    • Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study
    • Pajno GB, Barberio G, De Luca F, Morabito L, Parmiani S. Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study. Clin Exp Allergy 2001; 31(9): 1392-1397.
    • (2001) Clin Exp Allergy , vol.31 , Issue.9 , pp. 1392-1397
    • Pajno, G.B.1    Barberio, G.2    De Luca, F.3    Morabito, L.4    Parmiani, S.5
  • 82
    • 34447132918 scopus 로고    scopus 로고
    • Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study
    • The PAT investigator group
    • Jacobsen L, Niggemann B, Dreborg S, et al. (The PAT investigator group). Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study. Allergy 2007; 62(8): 943-948.
    • (2007) Allergy , vol.62 , Issue.8 , pp. 943-948
    • Jacobsen, L.1    Niggemann, B.2    Dreborg, S.3
  • 83
    • 35948974348 scopus 로고    scopus 로고
    • Prevention of allergic respiratory disease in infants: Current aspects and future perspectives
    • Holt PG, Sly PD. Prevention of allergic respiratory disease in infants: current aspects and future perspectives. Curr Opin Allergy Clin Immunol 2007; 7(6): 547-555.
    • (2007) Curr Opin Allergy Clin Immunol , vol.7 , Issue.6 , pp. 547-555
    • Holt, P.G.1    Sly, P.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.