메뉴 건너뛰기




Volumn 11, Issue 4, 2005, Pages 446-449

A chimeric human-cat fusion protein blocks cat-induced allergy

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; FEL D1 ALLERGEN; HISTAMINE; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN FC FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE SYK; UNCLASSIFIED DRUG;

EID: 17644388057     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1219     Document Type: Article
Times cited : (182)

References (28)
  • 1
    • 0037434895 scopus 로고    scopus 로고
    • Effect of anti-IgE therapy in patients with peanut allergy
    • Leung, D.Y.M. et al. Effect of anti-IgE therapy in patients with peanut allergy. N. Engl. J. Med. 348, 986-993 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 986-993
    • Leung, D.Y.M.1
  • 2
    • 0034713675 scopus 로고    scopus 로고
    • Immunologically mediated signaling in basophils and mast cells: Finding therapeutic targets for allergic diseases in the human FcεRI signaling pathway
    • Oliver, J.M., Kepley, C.L., Ortega, E. & Wilson, B.S. Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcεRI signaling pathway. Immunopharmacology 48, 269-281 (2000).
    • (2000) Immunopharmacology , vol.48 , pp. 269-281
    • Oliver, J.M.1    Kepley, C.L.2    Ortega, E.3    Wilson, B.S.4
  • 3
    • 0030929805 scopus 로고    scopus 로고
    • Fc receptor biology
    • Daeron, M. Fc receptor biology. Annu. Rev. Immunol. 15, 203-234 (1997).
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 203-234
    • Daeron, M.1
  • 4
    • 0033624162 scopus 로고    scopus 로고
    • Negative regulation of FcεRI signaling by FcγR II costimulation in human blood basophils
    • Kepley, C.L. et al. Negative regulation of FcεRI signaling by FcγR II costimulation in human blood basophils. J. Allergy Clin. Immunol. 106, 337-348 (2000).
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 337-348
    • Kepley, C.L.1
  • 5
    • 0028851582 scopus 로고
    • The same tyrosine-based inhibition motif, in the intracytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation
    • Daeron, M. et al. The same tyrosine-based inhibition motif, in the intracytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation. Immunity 3, 635-646 (1995).
    • (1995) Immunity , vol.3 , pp. 635-646
    • Daeron, M.1
  • 6
    • 0032519010 scopus 로고    scopus 로고
    • Fcε Receptor I-associated lyn-dependent phosphorylation of Fcγ Receptor MB during negative regulation of mast cell activation
    • Malbec, O. et al. Fcε Receptor I-associated lyn-dependent phosphorylation of Fcγ Receptor MB during negative regulation of mast cell activation. J. Immunol. 160, 1647-1658 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 1647-1658
    • Malbec, O.1
  • 7
    • 8244232951 scopus 로고    scopus 로고
    • Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγR IIB during negative regulation of IgE-dependent mouse mast cell activation
    • Fong, D.C. et al. Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγR IIB during negative regulation of IgE-dependent mouse mast cell activation. Immunol. Lett. 54, 83-91 (1996).
    • (1996) Immunol. Lett. , vol.54 , pp. 83-91
    • Fong, D.C.1
  • 8
    • 0034502164 scopus 로고    scopus 로고
    • Activating and inhibitory signaling in mast cells: New opportunities for therapeutic intervention?
    • Ott, V.L. & Cambier, J.C. Activating and inhibitory signaling in mast cells: New opportunities for therapeutic intervention? J. Allergy Clin. Immunol. 106, 429-440 (2000).
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 429-440
    • Ott, V.L.1    Cambier, J.C.2
  • 9
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB
    • Ono, M., Bolland, S., Tempst, P. & Ravetch, J.V. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. Nature 383, 263-266 (1996).
    • (1996) Nature , vol.383 , pp. 263-266
    • Ono, M.1    Bolland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 10
    • 0036100524 scopus 로고    scopus 로고
    • A novel human immunoglobulin Fcγ-Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation
    • Zhu, D., Kepley, C.L., Zhang, M., Zhang, K. & Saxon, A. A novel human immunoglobulin Fcγ-Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation. Nat. Med. 8, 518-521 (2002).
    • (2002) Nat. Med. , vol.8 , pp. 518-521
    • Zhu, D.1    Kepley, C.L.2    Zhang, M.3    Zhang, K.4    Saxon, A.5
  • 11
    • 3042778582 scopus 로고    scopus 로고
    • A bispecific antibody against human IgE and human FcγRII that inhibits antigen-induced histamine release by human mast cells and basophils
    • Tam, S.W., Demissie, S., Thomas, D. & Daeron, M. A bispecific antibody against human IgE and human FcγRII that inhibits antigen-induced histamine release by human mast cells and basophils. Allergy 59, 772-780 (2004).
    • (2004) Allergy , vol.59 , pp. 772-780
    • Tam, S.W.1    Demissie, S.2    Thomas, D.3    Daeron, M.4
  • 12
    • 4143134268 scopus 로고    scopus 로고
    • Co-aggregation of FcγRII with FcεRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes
    • Kepley, C.L. et al. Co-aggregation of FcγRII With FcεRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes. J. Biol. Chem. 279, 35139-35149 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 35139-35149
    • Kepley, C.L.1
  • 13
    • 0028842110 scopus 로고
    • Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors
    • Daeron, M. et al. Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors. J. Clin. Invest. 95, 577-585 (1995).
    • (1995) J. Clin. Invest. , vol.95 , pp. 577-585
    • Daeron, M.1
  • 14
    • 0026093770 scopus 로고
    • Amino acid sequence of Fel d1, the major allergen of the domestic cat: Protein sequence analysis and cDNA cloning
    • Morgenstern, J.P. et al. Amino acid sequence of Fel d1, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning. Proc. Natl. Acad. Sci. USA 88, 9690-9694 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9690-9694
    • Morgenstern, J.P.1
  • 15
    • 0036857557 scopus 로고    scopus 로고
    • High-level expression of immunoreactive recombinant cat allergen (Fel d1): Targeting to antigen-presenting cells
    • Vailes, L. D. et al. High-level expression of immunoreactive recombinant cat allergen (Fel d1): Targeting to antigen-presenting cells. J. Allergy Clin. Immunol. 110, 757-762 (2002).
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 757-762
    • Vailes, L.D.1
  • 16
    • 0004198722 scopus 로고
    • Protein engineering of antibody binding site: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
    • Huston, J.S. et al. Protein engineering of antibody binding site: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85, 5879-5883 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5879-5883
    • Huston, J.S.1
  • 17
    • 0028339125 scopus 로고
    • Identification of the IgG binding site of the human low affinity receptor for IgG FcγRII
    • Hulett, M.D., Witort, E., Brinkworth, R.I., Mckenzie, I.F. & Hogarth, P.M. Identification of the IgG binding site of the human low affinity receptor for IgG FcγRII. J. Biol. Chem. 269, 15287-15293 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 15287-15293
    • Hulett, M.D.1    Witort, E.2    Brinkworth, R.I.3    Mckenzie, I.F.4    Hogarth, P.M.5
  • 18
    • 0030449653 scopus 로고    scopus 로고
    • Human HMC-1 mast cells exclusively express the FcγR II subtype of IgG receptor
    • Wedi, B., Lewrick, H., Butterfield, J.H. & Kapp, A. Human HMC-1 mast cells exclusively express the FcγR II subtype of IgG receptor. Arch. Dermatol. Res. 289, 21-27 (1996).
    • (1996) Arch. Dermatol. Res. , vol.289 , pp. 21-27
    • Wedi, B.1    Lewrick, H.2    Butterfield, J.H.3    Kapp, A.4
  • 19
    • 0034669970 scopus 로고    scopus 로고
    • Multiple defects in FcεRI signaling in Syk-deficient nonreleaser basophilsand IL-3-induced recovery of Syk expression and secretion
    • Kepley, C.L., Youssef, L., Andrews, R.P., Wilson, B.S. & Oliver, J.M. Multiple defects in FcεRI signaling in Syk-deficient nonreleaser basophilsand IL-3-induced recovery of Syk expression and secretion. J. Immunol. 165, 5913-5920 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 5913-5920
    • Kepley, C.L.1    Youssef, L.2    Andrews, R.P.3    Wilson, B.S.4    Oliver, J.M.5
  • 20
    • 0031573626 scopus 로고    scopus 로고
    • Early and late events in FcsRI signal transduction in human cultured mast cells
    • Suzuki, H. et al. Early and late events in FcsRI signal transduction in human cultured mast cells. J. Immunol. 159, 5881-5888 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 5881-5888
    • Suzuki, H.1
  • 21
    • 0030586677 scopus 로고    scopus 로고
    • Anaphylaxis mediated through a humanized high affinity IgE receptor
    • Dombrowicz, D. et al. Anaphylaxis mediated through a humanized high affinity IgE receptor. J. Immunol. 157, 1645-1651 (1996).
    • (1996) J. Immunol. , vol.157 , pp. 1645-1651
    • Dombrowicz, D.1
  • 22
    • 13344284650 scopus 로고    scopus 로고
    • Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor α chain respond to human IgE in mast cell degranulation and in allergic reactions
    • Fung-Leung, W.P. et al. Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor α chain respond to human IgE in mast cell degranulation and in allergic reactions. J. Exp. Med. 183, 49-56 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 49-56
    • Fung-Leung, W.P.1
  • 23
    • 4344605211 scopus 로고    scopus 로고
    • Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional protein
    • Zhang, K. et al. Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional protein. J. Allergy Clin. Immunol. 114, 321-327 (2004).
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 321-327
    • Zhang, K.1
  • 24
    • 0027729893 scopus 로고
    • Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene
    • Dombrowicz, D., Flamand, V., Brigman, K.K., Koller, B.H. & Kinet, J.P. Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene. Cell 75, 969-976 (1993).
    • (1993) Cell , vol.75 , pp. 969-976
    • Dombrowicz, D.1    Flamand, V.2    Brigman, K.K.3    Koller, B.H.4    Kinet, J.P.5
  • 25
    • 0029975082 scopus 로고    scopus 로고
    • Fel d1-specific IgG antibodies induced by natural exposure have blocking activity in skin test
    • Witteman, A. M. et al. Fel d1-specific IgG antibodies induced by natural exposure have blocking activity in skin test. Int. Arch. Allergy Immunol. 109, 369-375 (1996).
    • (1996) Int. Arch. Allergy Immunol. , vol.109 , pp. 369-375
    • Witteman, A.M.1
  • 26
    • 0035835981 scopus 로고    scopus 로고
    • Sensitization, asthma, and a modified Th2 response in children exposed to cat allergen: A population-based cross-sectional study
    • Platts-Mills, T., Vaughan, J., Squillace, S., Woodfolk, J. & Sporik, R. Sensitization, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 357, 752-756 (2001).
    • (2001) Lancet , vol.357 , pp. 752-756
    • Platts-Mills, T.1    Vaughan, J.2    Squillace, S.3    Woodfolk, J.4    Sporik, R.5
  • 27
    • 0029029377 scopus 로고
    • Identification and partial characterization of a unique marker for human basophils
    • Kepley, C.L., Craig, S.S. and Schwartz, L.B. Identification and partial characterization of a unique marker for human basophils. J. Immunol. 154, 6548-6555 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 6548-6555
    • Kepley, C.L.1    Craig, S.S.2    Schwartz, L.B.3
  • 28
    • 0029085275 scopus 로고
    • A computer-controlled research ventilator for small animals: Design and evaluation
    • Schuessler, T. F., and Bates, J.H. A computer-controlled research ventilator for small animals: design and evaluation. IEEE Trans. Biomed. Eng. 42, 860-866 (1995).
    • (1995) IEEE Trans. Biomed. Eng. , vol.42 , pp. 860-866
    • Schuessler, T.F.1    Bates, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.