Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: Implications for drug-target interactions

Molecular Cancer Therapeutics

Volumn 7, Issue 10, 2008, Pages 3150-3159

  Liaw, Tracy Y E ^a,b   Salam, Noeris K ^c   McKay, Matthew J ^d,e   Cunningham, Anne M ^b   Hibbs, David E ^c   Kavallaris, Maria ^a,b  

^a CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d Australian Proteome Analysis Facility   (Australia)

^e MACQUARIE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; ALANINE; ASPARAGINE; BETA TUBULIN; COLCHICINE; EPOTHILONE B; LYSINE; PACLITAXEL; SERINE; THREONINE; VINBLASTINE; 2-METHOXYESTRADIOL; DRUG DERIVATIVE; ESTRADIOL; TUBULIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROSS RESISTANCE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MICROTUBULE ASSEMBLY; MOLECULAR INTERACTION; PRIORITY JOURNAL; ACETYLATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECT; DRUG RESISTANCE; GENETICS; IMMUNOHISTOCHEMISTRY; LYMPHATIC LEUKEMIA; MITOSIS; MOLECULAR GENETICS; MUTATION; PATHOLOGY; STRUCTURAL HOMOLOGY; TUMOR CELL LINE;

ACETYLATION; AMINO ACID SEQUENCE; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; ESTRADIOL; G2 PHASE; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, CONFOCAL; MITOSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; STRUCTURAL HOMOLOGY, PROTEIN; TUBULIN;

EID: 55749087503     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0442     Document Type: Article

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