The interaction of the B-ring of colchicine with α-Tubulin: A novel footprinting approach

Journal of Molecular Biology

Volumn 303, Issue 5, 2000, Pages 679-692

  Chaudhuri, Asish R ^a   Seetharamalu, P ^b   Schwarz, Patricia M ^a   Hausheer, F H ^b   Ludueña, Richard F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b BioNumerik Pharmaceuticals Inc   (United States)

Author keywords

Alkylation; Colchicine; Footprinting; Sulfhydryl groups; Tubulin

Indexed keywords

ALPHA TUBULIN; COLCHICINE; PACLITAXEL; VINCA ALKALOID;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CHEMOTHERAPY; CONFORMATIONAL TRANSITION; DRUG BINDING; LIGAND BINDING; MOLECULAR MODEL; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STABILITY; TECHNIQUE;

EID: 0034634366     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4156     Document Type: Article

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