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Volumn 23, Issue 4, 2008, Pages 399-409

Age-related changes of calcineurin and Akt1/protein kinase Bα (Akt1/PKBα) immunoreactivity in the mouse hippocampal CA1 sector: An immunohistochemical study

Author keywords

Aging; Akt1 PKB ; Calcineurin; Hippocampal CA1 sector; Immunohistochemistry; Mice

Indexed keywords

CALCINEURIN; PROTEIN KINASE B;

EID: 55149116095     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-008-9103-8     Document Type: Article
Times cited : (10)

References (52)
  • 1
    • 0027453227 scopus 로고
    • Postischemic changes of intracellular second messengers in the gerbil brain after long-term survival: An autoradiographic study
    • T Araki H Kato Y Kanai K Kogure 1993 Postischemic changes of intracellular second messengers in the gerbil brain after long-term survival: an autoradiographic study Neuroscience 53 829 836
    • (1993) Neuroscience , vol.53 , pp. 829-836
    • Araki, T.1    Kato, H.2    Kanai, Y.3    Kogure, K.4
  • 2
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • CA Barnes 1979 Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat J Comp Physiol Psychol 93 74 104
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 3
    • 0024162045 scopus 로고
    • Aging and the physiology of spatial memory
    • CA Barnes 1988 Aging and the physiology of spatial memory Neurobiol Aging 9 563 568
    • (1988) Neurobiol Aging , vol.9 , pp. 563-568
    • Barnes, C.A.1
  • 4
    • 0030463470 scopus 로고    scopus 로고
    • 2+- and stimulus duration-dependent switch for hippocampal gene expression
    • 2+- and stimulus duration-dependent switch for hippocampal gene expression Cell 87 1203 1214
    • (1996) Cell , vol.87 , pp. 1203-1214
    • Bito, H.1    Deisseroth, K.2    Tsien, R.W.3
  • 5
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
    • A Brunet SR Datta ME Greenberg 2001 Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway Curr Opin Neurobiol 11 297 305
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 6
    • 0032881288 scopus 로고    scopus 로고
    • AKT/PKB and other D3 phosphoinositide-regulated kinases:kinase activation by phosphoinositide-dependent phosphorylation
    • TO Chan SE Rittenhouse PN Tsichlis 1999 AKT/PKB and other D3 phosphoinositide-regulated kinases:kinase activation by phosphoinositide- dependent phosphorylation Annu Rev Biochem 68 965 1014
    • (1999) Annu Rev Biochem , vol.68 , pp. 965-1014
    • Chan, T.O.1    Rittenhouse, S.E.2    Tsichlis, P.N.3
  • 8
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • H Cho JL Thorvaldsen Q Chu F Feng MJ Birnbaum 2001 Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice J Biol Chem 276 38349 38352
    • (2001) J Biol Chem , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 9
    • 0026006501 scopus 로고
    • Molecular cloning and characterization of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families
    • PJ Coffer JR Woodgett 1991 Molecular cloning and characterization of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families Eur J Biochem 201 475 481
    • (1991) Eur J Biochem , vol.201 , pp. 475-481
    • Coffer, P.J.1    Woodgett, J.R.2
  • 10
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • GR Crabtree EN Olson 2002 NFAT signaling: choreographing the social lives of cells Cell [Suppl] 109 S67 S79
    • (2002) Cell [Suppl] , vol.109
    • Crabtree, G.R.1    Olson, E.N.2
  • 11
    • 0028169349 scopus 로고
    • The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: Relationship to calcineurin
    • TM Dawson JP Steiner WE Lyons M Fotuhi M Blue SH Snyder 1994 The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin Neuroscience 62 569 580
    • (1994) Neuroscience , vol.62 , pp. 569-580
    • Dawson, T.M.1    Steiner, J.P.2    Lyons, W.E.3    Fotuhi, M.4    Blue, M.5    Snyder, S.H.6
  • 12
    • 0024162989 scopus 로고
    • Age-dependent alterations in hippocampal synaptic plasticity: Relation to memory disorders
    • L DeToledo-Morrell Y Geinisman F Morrell 1988 Age-dependent alterations in hippocampal synaptic plasticity: relation to memory disorders Neurobiol Aging 9 581 590
    • (1988) Neurobiol Aging , vol.9 , pp. 581-590
    • Detoledo-Morrell, L.1    Geinisman, Y.2    Morrell, F.3
  • 13
    • 0028649481 scopus 로고
    • The calcium rationale in aging and Alzheimer's disease. Evidence from an animal model of normal aging
    • JF Disterhoft JR Moyer Jr LT Thompson 1994 The calcium rationale in aging and Alzheimer's disease. Evidence from an animal model of normal aging Ann NY Acad Sci 747 382 406
    • (1994) Ann NY Acad Sci , vol.747 , pp. 382-406
    • Disterhoft, J.F.1    Moyer Jr., J.R.2    Thompson, L.T.3
  • 16
    • 0035861386 scopus 로고    scopus 로고
    • The hippocampus and declarative memory: Cognitive mechanisms and neural codes
    • H Eichenbaum 2001 The hippocampus and declarative memory: cognitive mechanisms and neural codes Behav Brain Res 127 199 207
    • (2001) Behav Brain Res , vol.127 , pp. 199-207
    • Eichenbaum, H.1
  • 17
  • 18
    • 0032737984 scopus 로고    scopus 로고
    • Involvement of hippocampal synaptic plasticity in age-related memory decline
    • TC Foster 1999 Involvement of hippocampal synaptic plasticity in age-related memory decline Brain Res Rev 30 236 249
    • (1999) Brain Res Rev , vol.30 , pp. 236-249
    • Foster, T.C.1
  • 19
    • 0031451847 scopus 로고    scopus 로고
    • 2+-dependent processes: Relation to hippocampal synaptic plasticity
    • 2+- dependent processes: relation to hippocampal synaptic plasticity Hippocampus 7 602 612
    • (1997) Hippocampus , vol.7 , pp. 602-612
    • Foster, T.C.1    Norris, C.M.2
  • 21
    • 0027723549 scopus 로고
    • Animal models of normal aging: Relationship between cognitive decline and markers in hippocampal circuitry
    • M Gallagher MM Nicolle 1993 Animal models of normal aging: relationship between cognitive decline and markers in hippocampal circuitry Behav Brain Res 57 155 162
    • (1993) Behav Brain Res , vol.57 , pp. 155-162
    • Gallagher, M.1    Nicolle, M.M.2
  • 23
    • 0043258253 scopus 로고
    • Loss of perforated synapses in the dentate gyrus: Morphological substrate of memory deficit in aged rats
    • Y Geinisman L Toledo-Morrell F Morrell 1986 Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats Proc Natl Acad Sci USA 83 3027 3031
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 3027-3031
    • Geinisman, Y.1    Toledo-Morrell, L.2    Morrell, F.3
  • 24
    • 0023032057 scopus 로고
    • The distribution of calcineurin in rat brain by light and electron microscope immunohistochemistry and enzyme-immunoassay
    • S Goto Y Matsuoka Y Mihara N Inoue E Miyamoto 1986 The distribution of calcineurin in rat brain by light and electron microscope immunohistochemistry and enzyme-immunoassay Brain Res 397 161 172
    • (1986) Brain Res , vol.397 , pp. 161-172
    • Goto, S.1    Matsuoka, Y.2    Mihara, Y.3    Inoue, N.4    Miyamoto, E.5
  • 25
    • 34247174374 scopus 로고    scopus 로고
    • Age-related changes of astrocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sector
    • N Hayakawa H Kato T Araki 2007 Age-related changes of astrocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sector Mech Ageing Dev 128 311 316
    • (2007) Mech Ageing Dev , vol.128 , pp. 311-316
    • Hayakawa, N.1    Kato, H.2    Araki, T.3
  • 26
    • 18844411053 scopus 로고    scopus 로고
    • Effects of age on immunohistochemical changes in the mouse hippocampus
    • T Himeda K Mizuno H Kato T Araki 2006 Effects of age on immunohistochemical changes in the mouse hippocampus Mech Ageing Dev 126 673 677
    • (2006) Mech Ageing Dev , vol.126 , pp. 673-677
    • Himeda, T.1    Mizuno, K.2    Kato, H.3    Araki, T.4
  • 28
    • 0023128675 scopus 로고
    • Differential localization of calmodulin-dependent enzymes in rat brain: Evidence for selective expression of cyclic nucleotide phosphodiesterase in specific neurons
    • RL Kincaid CD Balaban ML Billingsley 1987 Differential localization of calmodulin-dependent enzymes in rat brain: evidence for selective expression of cyclic nucleotide phosphodiesterase in specific neurons Proc Natl Acad Sci USA 84 1118 1122
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1118-1122
    • Kincaid, R.L.1    Balaban, C.D.2    Billingsley, M.L.3
  • 29
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • T Kirino 1982 Delayed neuronal death in the gerbil hippocampus following ischemia Brain Res 239 57 69
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 30
    • 0001018554 scopus 로고
    • Calcineurin: A calcium- and calmodulin-binding protein of the nervous system
    • CB Klee TH Crouch MH Krinks 1979 Calcineurin: a calcium- and calmodulin-binding protein of the nervous system Proc Natl Acad Sci USA 76 6270 6273
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 6270-6273
    • Klee, C.B.1    Crouch, T.H.2    Krinks, M.H.3
  • 32
    • 0024158607 scopus 로고
    • Hippocampal neurobiological mechanisms of age-related memory dysfunction
    • PW Landfield 1988 Hippocampal neurobiological mechanisms of age-related memory dysfunction Neurobiol Aging 9 571 579
    • (1988) Neurobiol Aging , vol.9 , pp. 571-579
    • Landfield, P.W.1
  • 34
    • 34250788809 scopus 로고    scopus 로고
    • Akt/PKB signaling: Navigating downstream
    • BD Manning LC Cantley 2007 Akt/PKB signaling: navigating downstream Cell 129 1261 1274
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 35
    • 0032498227 scopus 로고    scopus 로고
    • Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
    • IM Mansuy M Mayford B Jacob ER Kandel ME Bach 1998 Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory Cell 92 39 49
    • (1998) Cell , vol.92 , pp. 39-49
    • Mansuy, I.M.1    Mayford, M.2    Jacob, B.3    Kandel, E.R.4    Bach, M.E.5
  • 37
    • 0033230623 scopus 로고    scopus 로고
    • Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles
    • MM Mesulam 1999 Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles Neuron 24 521 529
    • (1999) Neuron , vol.24 , pp. 521-529
    • Mesulam, M.M.1
  • 39
    • 0033503975 scopus 로고    scopus 로고
    • Survival- and death-promoting events after transient cerebral ischemia: Phophorylation of Ark, release of cytochrome c and activation of caspase-like proteases
    • YB Ouyang Y Tan M Comb CL Liu ME Martone BK Siesjo BR Hu 1999 Survival- and death-promoting events after transient cerebral ischemia: phophorylation of Ark, release of cytochrome c and activation of caspase-like proteases J Cereb Blood Flow Metab 19 1126 1135
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1126-1135
    • Ouyang, Y.B.1    Tan, Y.2    Comb, M.3    Liu, C.L.4    Martone, M.E.5    Siesjo, B.K.6    Hu, B.R.7
  • 40
    • 0020067965 scopus 로고
    • Temporal profile of neuronal damage in a model of transient forebrain ischemia
    • WA Pulsinelli JB Brierley F Plum 1982 Temporal profile of neuronal damage in a model of transient forebrain ischemia Ann Neurol 11 491 498
    • (1982) Ann Neurol , vol.11 , pp. 491-498
    • Pulsinelli, W.A.1    Brierley, J.B.2    Plum, F.3
  • 41
    • 0342980927 scopus 로고    scopus 로고
    • Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells
    • M Salinas R Lopez-Valdaliso D Martin A Alvarez A Cuadrado 2000 Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells Mol Cell Neurosci 15 156 169
    • (2000) Mol Cell Neurosci , vol.15 , pp. 156-169
    • Salinas, M.1    Lopez-Valdaliso, R.2    Martin, D.3    Alvarez, A.4    Cuadrado, A.5
  • 42
    • 0034746573 scopus 로고    scopus 로고
    • Akt1/PKBα protects PC12 cells against the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals
    • M Salinas D Martin A Alvarez A Cuadrado 2001 Akt1/PKBα protects PC12 cells against the parkinsonism-inducing neurotoxin 1-methyl-4- phenylpyridinium and reduces the levels of oxygen-free radicals Mol Cell Neurosci 17 67 77
    • (2001) Mol Cell Neurosci , vol.17 , pp. 67-77
    • Salinas, M.1    Martin, D.2    Alvarez, A.3    Cuadrado, A.4
  • 43
    • 36749008436 scopus 로고    scopus 로고
    • Damage to oligodendrocytes in the striatum after MPTP neurotoxicity in mice
    • S Takagi N Hayakawa H Kimoto H Kato T Araki 2007 Damage to oligodendrocytes in the striatum after MPTP neurotoxicity in mice J Neural Transm 114 1553 1557
    • (2007) J Neural Transm , vol.114 , pp. 1553-1557
    • Takagi, S.1    Hayakawa, N.2    Kimoto, H.3    Kato, H.4    Araki, T.5
  • 48
    • 0032498272 scopus 로고    scopus 로고
    • Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
    • DG Winder IM Mansuy M Osman TM Moallem ER Kandel 1998 Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin Cell 92 25 37
    • (1998) Cell , vol.92 , pp. 25-37
    • Winder, D.G.1    Mansuy, I.M.2    Osman, M.3    Moallem, T.M.4    Kandel, E.R.5
  • 49
    • 0035407298 scopus 로고    scopus 로고
    • Roles of serine/threonine phosphatase in hippocampal synaptic plasticity
    • DG Winder JD Sweatt 2001 Roles of serine/threonine phosphatase in hippocampal synaptic plasticity Nat Rev Neurosci 2 461 474
    • (2001) Nat Rev Neurosci , vol.2 , pp. 461-474
    • Winder, D.G.1    Sweatt, J.D.2
  • 50
    • 0032569026 scopus 로고    scopus 로고
    • Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis
    • H Zhou SA Summers MJ Birnbaum RN Pittman 1998 Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis J Biol Chem 273 16568 16575
    • (1998) J Biol Chem , vol.273 , pp. 16568-16575
    • Zhou, H.1    Summers, S.A.2    Birnbaum, M.J.3    Pittman, R.N.4
  • 52
    • 0032128301 scopus 로고    scopus 로고
    • Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress
    • W Zundel A Giaccia 1998 Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress Genes Dev 12 1941 1946
    • (1998) Genes Dev , vol.12 , pp. 1941-1946
    • Zundel, W.1    Giaccia, A.2


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