-
1
-
-
0003770851
-
-
American Diabetes Association. Diabetes Statistics. http://www.diabetes. org/diabetes-statistics.jsp.
-
Diabetes Statistics
-
-
-
2
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
S Wild G Roglic A Green R Sicree H King 2004 Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 27 1047 1053
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
4
-
-
0033552883
-
Atherosclerosis-an inflammatory disease
-
R Ross 1999 Atherosclerosis-an inflammatory disease N Engl J Med 340 115 126
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
5
-
-
54949159429
-
-
Centers for Disease Control and Prevention. 2004. U.S Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta GA.
-
Centers for Disease Control and Prevention. 2004. U.S Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta GA.
-
-
-
-
6
-
-
0034611780
-
Coronary heart disease in patients with diabetes
-
SM Haffner 2000 Coronary heart disease in patients with diabetes N Engl J Med 342 1040 1042
-
(2000)
N Engl J Med
, vol.342
, pp. 1040-1042
-
-
Haffner, S.M.1
-
7
-
-
0032560807
-
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
-
SM Haffner S Lehto T Ronnemaa K Pyorala M Laakso 1998 Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction N Engl J Med 339 229 234
-
(1998)
N Engl J Med
, vol.339
, pp. 229-234
-
-
Haffner, S.M.1
Lehto, S.2
Ronnemaa, T.3
Pyorala, K.4
Laakso, M.5
-
8
-
-
0034912564
-
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up
-
FB Hu MJ Stampfer CG Solomon S Liu WC Willett FE Speizer 2001 The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up Arch Intern Med 161 1717 1723
-
(2001)
Arch Intern Med
, vol.161
, pp. 1717-1723
-
-
Hu, F.B.1
Stampfer, M.J.2
Solomon, C.G.3
Liu, S.4
Willett, W.C.5
Speizer, F.E.6
-
9
-
-
0037327402
-
Oxidative stress and diabetic neuropathy: A new understanding of an old problem
-
EL Feldman 2003 Oxidative stress and diabetic neuropathy: a new understanding of an old problem J Clin Invest 111 431 433
-
(2003)
J Clin Invest
, vol.111
, pp. 431-433
-
-
Feldman, E.L.1
-
10
-
-
0032511606
-
Some answers, more controversy, from UKPDS. United Kingdom Prospective Diabetes Study
-
DM Nathan 1998 Some answers, more controversy, from UKPDS. United Kingdom Prospective Diabetes Study Lancet 352 832 833
-
(1998)
Lancet
, vol.352
, pp. 832-833
-
-
Nathan, D.M.1
-
11
-
-
0024430867
-
The Wisconsin Epidemiologic Study of Diabetic Retinopathy: A review
-
R Klein BE Klien SE Moss 1989 The Wisconsin Epidemiologic Study of Diabetic Retinopathy: a review Diabetes Metab Rev 5 559 570
-
(1989)
Diabetes Metab Rev
, vol.5
, pp. 559-570
-
-
Klein, R.1
Klien, B.E.2
Moss, S.E.3
-
12
-
-
0032908858
-
Hyperglycemia and cardiovascular disease in type 2 diabetes
-
M Laakso 1999 Hyperglycemia and cardiovascular disease in type 2 diabetes Diabetes 48 937 942
-
(1999)
Diabetes
, vol.48
, pp. 937-942
-
-
Laakso, M.1
-
13
-
-
0031047740
-
The mystery of diabetes and atherosclerosis: Time for a new plot
-
CF Semenkovich JW Heinecke 1997 The mystery of diabetes and atherosclerosis: time for a new plot Diabetes 46 327 334
-
(1997)
Diabetes
, vol.46
, pp. 327-334
-
-
Semenkovich, C.F.1
Heinecke, J.W.2
-
14
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
DCCT Research Group
-
DCCT Research Group 1993 The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus N Engl J Med 329 977 986
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
15
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
-
UKPDS Research Group
-
UKPDS Research Group 1998 Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group Lancet 352 837 853
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
16
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group
-
UKPDS Research Group
-
UKPDS Research Group 1998 Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group Lancet 352 854 865
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
17
-
-
0034628425
-
Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
-
DCCT/EDIC Research Group
-
DCCT/EDIC Research Group 2000 Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group N Engl J Med 342 381 389
-
(2000)
N Engl J Med
, vol.342
, pp. 381-389
-
-
-
19
-
-
45149131667
-
Effects of intensive glucose lowering in type 2 diabetes
-
The Action to Control Cardiovascular Risk in Diabetes Study Group
-
The Action to Control Cardiovascular Risk in Diabetes Study Group 2008 Effects of intensive glucose lowering in type 2 diabetes N Engl J Med 358 2545 2559
-
(2008)
N Engl J Med
, vol.358
, pp. 2545-2559
-
-
-
20
-
-
45149133036
-
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
-
The ADVANCE Collaborative Group
-
The ADVANCE Collaborative Group 2008 Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes N Engl J Med 358 2560 2572
-
(2008)
N Engl J Med
, vol.358
, pp. 2560-2572
-
-
-
21
-
-
45149118855
-
Intensive glycemic control in the ACCORD and ADVANCE trials
-
RG Dluhy GT McMahon 2008 Intensive glycemic control in the ACCORD and ADVANCE trials N Engl J Med 358 2630 2633
-
(2008)
N Engl J Med
, vol.358
, pp. 2630-2633
-
-
Dluhy, R.G.1
McMahon, G.T.2
-
22
-
-
33947716172
-
Endothelial function and dysfunction: Testing and clinical relevance
-
JE Deanfield JP Halcox TJ Rabelink 2007 Endothelial function and dysfunction: testing and clinical relevance Circulation 115 1285 1295
-
(2007)
Circulation
, vol.115
, pp. 1285-1295
-
-
Deanfield, J.E.1
Halcox, J.P.2
Rabelink, T.J.3
-
23
-
-
33845742185
-
Mechanisms of disease: Endothelial dysfunction in insulin resistance and diabetes
-
C Rask-Madsen GL King 2007 Mechanisms of disease: endothelial dysfunction in insulin resistance and diabetes Nat Clin Pract Endocrinol Metab 3 46 56
-
(2007)
Nat Clin Pract Endocrinol Metab
, vol.3
, pp. 46-56
-
-
Rask-Madsen, C.1
King, G.L.2
-
24
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
M Brownlee 2001 Biochemistry and molecular cell biology of diabetic complications Nature 414 813 820
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
25
-
-
0034659178
-
Glycoxidation and lipoxidation in atherogenesis
-
JW Baynes SR Thorpe 2000 Glycoxidation and lipoxidation in atherogenesis Free Radic Biol Med 28 1708 1716
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1708-1716
-
-
Baynes, J.W.1
Thorpe, S.R.2
-
26
-
-
34250325126
-
Mechanisms for oxidative stress in diabetic cardiovascular disease
-
S Pennathur JW Heinecke 2007 Mechanisms for oxidative stress in diabetic cardiovascular disease Antioxid Redox Signal 9 955 969
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 955-969
-
-
Pennathur, S.1
Heinecke, J.W.2
-
27
-
-
34547875025
-
Oxidative stress and endothelial dysfunction in vascular disease
-
S Pennathur JW Heinecke 2007 Oxidative stress and endothelial dysfunction in vascular disease Curr Diab Rep 7 257 264
-
(2007)
Curr Diab Rep
, vol.7
, pp. 257-264
-
-
Pennathur, S.1
Heinecke, J.W.2
-
28
-
-
20744460199
-
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: A potential pathway for oxidative damage of retinal proteins in diabetes
-
S Pennathur Y Ido JI Heller J Byun R Danda P Pergola 2005 Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes J Biol Chem 280 22706 22714
-
(2005)
J Biol Chem
, vol.280
, pp. 22706-22714
-
-
Pennathur, S.1
Ido, Y.2
Heller, J.I.3
Byun, J.4
Danda, R.5
Pergola, P.6
-
29
-
-
0035057229
-
A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease
-
S Pennathur JD Wagner C Leeuwenburgh KN Litwak JW Heinecke 2001 A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease J Clin Invest 107 853 860
-
(2001)
J Clin Invest
, vol.107
, pp. 853-860
-
-
Pennathur, S.1
Wagner, J.D.2
Leeuwenburgh, C.3
Litwak, K.N.4
Heinecke, J.W.5
-
31
-
-
0028908348
-
Advanced protein glycosylation in diabetes and aging
-
M Brownlee 1995 Advanced protein glycosylation in diabetes and aging Annu Rev Med 46 223 234
-
(1995)
Annu Rev Med
, vol.46
, pp. 223-234
-
-
Brownlee, M.1
-
32
-
-
0037421493
-
Oxidative stress: New approaches to diagnosis and prognosis in atherosclerosis
-
JW Heinecke 2003 Oxidative stress: new approaches to diagnosis and prognosis in atherosclerosis Am J Cardiol 91 12A 16A
-
(2003)
Am J Cardiol
, vol.91
-
-
Heinecke, J.W.1
-
33
-
-
2542443475
-
Mechanisms of oxidative stress in diabetes: Implications for the pathogenesis of vascular disease and antioxidant therapy
-
S Pennathur JW Heinecke 2004 Mechanisms of oxidative stress in diabetes: implications for the pathogenesis of vascular disease and antioxidant therapy Front Biosci 9 565 574
-
(2004)
Front Biosci
, vol.9
, pp. 565-574
-
-
Pennathur, S.1
Heinecke, J.W.2
-
34
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
N Houstis ED Rosen ES Lander 2006 Reactive oxygen species have a causal role in multiple forms of insulin resistance Nature 440 944 948
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
35
-
-
0032913309
-
Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
-
JW Baynes SR Thorpe 1999 Role of oxidative stress in diabetic complications: a new perspective on an old paradigm Diabetes 48 1 9
-
(1999)
Diabetes
, vol.48
, pp. 1-9
-
-
Baynes, J.W.1
Thorpe, S.R.2
-
36
-
-
0023708392
-
Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing
-
JV Hunt RT Dean SP Wolff 1988 Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing Biochem J 256 205 212
-
(1988)
Biochem J
, vol.256
, pp. 205-212
-
-
Hunt, J.V.1
Dean, R.T.2
Wolff, S.P.3
-
37
-
-
0023950461
-
Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
-
M Brownlee A Cerami H Vlassara 1988 Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications N Engl J Med 318 1315 1321
-
(1988)
N Engl J Med
, vol.318
, pp. 1315-1321
-
-
Brownlee, M.1
Cerami, A.2
Vlassara, H.3
-
38
-
-
0027180882
-
Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation
-
TG Huggins MC Wells-Knecht NA Detorie JW Baynes SR Thorpe 1993 Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation J Biol Chem 268 12341 12347
-
(1993)
J Biol Chem
, vol.268
, pp. 12341-12347
-
-
Huggins, T.G.1
Wells-Knecht, M.C.2
Detorie, N.A.3
Baynes, J.W.4
Thorpe, S.R.5
-
40
-
-
0028245381
-
Detection of hydroxyl radicals by aromatic hydroxylation
-
H Kaur B Halliwell 1994 Detection of hydroxyl radicals by aromatic hydroxylation Methods Enzymol 233 67 82
-
(1994)
Methods Enzymol
, vol.233
, pp. 67-82
-
-
Kaur, H.1
Halliwell, B.2
-
41
-
-
0344837347
-
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy
-
HP Hammes X Du D Edelstein T Taguchi T Matsumura Q Ju 2003 Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy Nat Med 9 294 299
-
(2003)
Nat Med
, vol.9
, pp. 294-299
-
-
Hammes, H.P.1
Du, X.2
Edelstein, D.3
Taguchi, T.4
Matsumura, T.5
Ju, Q.6
-
42
-
-
0030934178
-
Clearance of pentosidine, an advanced glycation end-product, by different modalities of renal replacement therapy
-
T Miyata Y Ueda A Yoshido S Sugiyama Y Iida M Jadoul 1997 Clearance of pentosidine, an advanced glycation end-product, by different modalities of renal replacement therapy Kidney Int 51 880 887
-
(1997)
Kidney Int
, vol.51
, pp. 880-887
-
-
Miyata, T.1
Ueda, Y.2
Yoshido, A.3
Sugiyama, S.4
Iida, Y.5
Jadoul, M.6
-
43
-
-
0032910949
-
Alterations in nonenzymatic biochemistry in uremia: Origin and significance of "carbonyl stress" in long-term uremic complications
-
T Miyata C van Ypersele de Strihou K Kurokawa JW Baynes 1999 Alterations in nonenzymatic biochemistry in uremia: origin and significance of "carbonyl stress" in long-term uremic complications Kidney Int 55 389 399
-
(1999)
Kidney Int
, vol.55
, pp. 389-399
-
-
Miyata, T.1
Van Ypersele De Strihou, C.2
Kurokawa, K.3
Baynes, J.W.4
-
44
-
-
0031656155
-
Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: Is there oxidative stress in uremia?
-
T Miyata MX Fu K Kurokawa C van Ypersele de Strihou SR Thorpe JW Baynes 1998 Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia? Kidney Int 54 1290 1295
-
(1998)
Kidney Int
, vol.54
, pp. 1290-1295
-
-
Miyata, T.1
Fu, M.X.2
Kurokawa, K.3
Van Ypersele De Strihou, C.4
Thorpe, S.R.5
Baynes, J.W.6
-
45
-
-
0025945553
-
Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo
-
DG Dyer JA Blackledge SR Thorpe JW Baynes 1991 Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo J Biol Chem 266 11654 11660
-
(1991)
J Biol Chem
, vol.266
, pp. 11654-11660
-
-
Dyer, D.G.1
Blackledge, J.A.2
Thorpe, S.R.3
Baynes, J.W.4
-
47
-
-
0035063226
-
Transition metals redox: Reviving an old plot for diabetic vascular disease
-
VM Monnier 2001 Transition metals redox: reviving an old plot for diabetic vascular disease J Clin Invest 107 799 801
-
(2001)
J Clin Invest
, vol.107
, pp. 799-801
-
-
Monnier, V.M.1
-
48
-
-
0026675759
-
Pentosidine formation in skin correlates with the severity of complications in individuals with long-standing IDDM
-
DR Sell A Lapolla P Odetti J Fogarty VM Monnier 1992 Pentosidine formation in skin correlates with the severity of complications in individuals with long-standing IDDM Diabetes 41 1286 1292
-
(1992)
Diabetes
, vol.41
, pp. 1286-1292
-
-
Sell, D.R.1
Lapolla, A.2
Odetti, P.3
Fogarty, J.4
Monnier, V.M.5
-
50
-
-
5644262427
-
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
-
S Pennathur C Bergt B Shao J Byun SY Kassim P Singh 2004 Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species J Biol Chem 279 42977 42983
-
(2004)
J Biol Chem
, vol.279
, pp. 42977-42983
-
-
Pennathur, S.1
Bergt, C.2
Shao, B.3
Byun, J.4
Kassim, S.Y.5
Singh, P.6
-
54
-
-
0018838058
-
Oxygen metabolism and the toxic properties of phagocytes
-
SJ Klebanoff 1980 Oxygen metabolism and the toxic properties of phagocytes Ann Intern Med 93 480 489
-
(1980)
Ann Intern Med
, vol.93
, pp. 480-489
-
-
Klebanoff, S.J.1
-
58
-
-
0035108136
-
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
-
S Sugiyama Y Okada GK Sukhova R Virmani JW Heinecke P Libby 2001 Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes Am J Pathol 158 879 891
-
(2001)
Am J Pathol
, vol.158
, pp. 879-891
-
-
Sugiyama, S.1
Okada, Y.2
Sukhova, G.K.3
Virmani, R.4
Heinecke, J.W.5
Libby, P.6
-
60
-
-
4444292600
-
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport
-
C Bergt S Pennathur X Fu J Byun K O'Brien TO McDonald 2004 The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport Proc Natl Acad Sci USA 101 13032 13037
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13032-13037
-
-
Bergt, C.1
Pennathur, S.2
Fu, X.3
Byun, J.4
O'Brien, K.5
McDonald, T.O.6
-
61
-
-
0030979720
-
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima
-
SL Hazen JW Heinecke 1997 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima J Clin Invest 99 2075 2081
-
(1997)
J Clin Invest
, vol.99
, pp. 2075-2081
-
-
Hazen, S.L.1
Heinecke, J.W.2
-
62
-
-
18044377401
-
NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease
-
H Cai 2005 NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease Circ Res 96 818 822
-
(2005)
Circ Res
, vol.96
, pp. 818-822
-
-
Cai, H.1
-
63
-
-
0034700790
-
Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICRO-HOPE substudy
-
Heart Outcomes Prevention Evaluation Study Investigators
-
Heart Outcomes Prevention Evaluation Study Investigators 2000 Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy Lancet 355 253 259
-
(2000)
Lancet
, vol.355
, pp. 253-259
-
-
-
65
-
-
28044455523
-
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
-
Y Gorin K Block J Hernandez B Bhandari B Wagner JL Barnes 2005 Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney J Biol Chem 280 39616 29626
-
(2005)
J Biol Chem
, vol.280
, pp. 39616-29626
-
-
Gorin, Y.1
Block, K.2
Hernandez, J.3
Bhandari, B.4
Wagner, B.5
Barnes, J.L.6
-
66
-
-
0037399439
-
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
-
U Landmesser S Dikalov SR Price L McCann T Fukai SM Holland 2003 Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension J Clin Invest 111 1201 1209
-
(2003)
J Clin Invest
, vol.111
, pp. 1201-1209
-
-
Landmesser, U.1
Dikalov, S.2
Price, S.R.3
McCann, L.4
Fukai, T.5
Holland, S.M.6
-
68
-
-
33646525680
-
Vascular NADPH oxidases as drug targets for novel antioxidant strategies
-
TJ Guzik DG Harrison 2006 Vascular NADPH oxidases as drug targets for novel antioxidant strategies Drug Discov Today 11 524 533
-
(2006)
Drug Discov Today
, vol.11
, pp. 524-533
-
-
Guzik, T.J.1
Harrison, D.G.2
-
70
-
-
0035943042
-
Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice
-
PJ Kuhlencordt R Gyurko F Han M Scherrer-Crosbie TH Aretz R Hajjar 2001 Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice Circulation 104 448 454
-
(2001)
Circulation
, vol.104
, pp. 448-454
-
-
Kuhlencordt, P.J.1
Gyurko, R.2
Han, F.3
Scherrer-Crosbie, M.4
Aretz, T.H.5
Hajjar, R.6
-
76
-
-
0027956982
-
Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency
-
R Bucala Z Makita G Vega S Grundy T Koschinsky A Cerami 1994 Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency Proc Natl Acad Sci USA 91 9441 9445
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9441-9445
-
-
Bucala, R.1
Makita, Z.2
Vega, G.3
Grundy, S.4
Koschinsky, T.5
Cerami, A.6
-
77
-
-
0025096104
-
Oxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
-
JV Hunt CC Smith SP Wolf 1990 Oxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose Diabetes 39 1420 1424
-
(1990)
Diabetes
, vol.39
, pp. 1420-1424
-
-
Hunt, J.V.1
Smith, C.C.2
Wolf, S.P.3
-
78
-
-
0027978458
-
Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway
-
M Kawamura JW Heinecke A Chait 1994 Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway J Clin Invest 94 771 778
-
(1994)
J Clin Invest
, vol.94
, pp. 771-778
-
-
Kawamura, M.1
Heinecke, J.W.2
Chait, A.3
-
79
-
-
0029923574
-
The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions
-
MX Fu JR Requena AJ Jenkins TJ Lyons JW Baynes SR Thorpe 1996 The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions J Biol Chem 271 9982 9986
-
(1996)
J Biol Chem
, vol.271
, pp. 9982-9986
-
-
Fu, M.X.1
Requena, J.R.2
Jenkins, A.J.3
Lyons, T.J.4
Baynes, J.W.5
Thorpe, S.R.6
-
80
-
-
15644362538
-
Carboxymethylethanolamine, a biomarker of phospholipid modification during the maillard reaction in vivo
-
JR Requena MU Ahmed CW Fountain TP Degenhardt S Reddy C Perez 1997 Carboxymethylethanolamine, a biomarker of phospholipid modification during the maillard reaction in vivo J Biol Chem 272 17473 17479
-
(1997)
J Biol Chem
, vol.272
, pp. 17473-17479
-
-
Requena, J.R.1
Ahmed, M.U.2
Fountain, C.W.3
Degenhardt, T.P.4
Reddy, S.5
Perez, C.6
-
81
-
-
0031051893
-
Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein
-
Pt 1
-
JR Requena MX Fu MU Ahmed AJ Jenkins TJ Lyons JW Baynes 1997 Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein Biochem J 322 Pt 1 317 325
-
(1997)
Biochem J
, vol.322
, pp. 317-325
-
-
Requena, J.R.1
Fu, M.X.2
Ahmed, M.U.3
Jenkins, A.J.4
Lyons, T.J.5
Baynes, J.W.6
-
83
-
-
0034682966
-
Oxidative stress and cardiovascular complications of diabetes: Isoprostanes as new markers on an old paradigm
-
A Mezzetti F Cipollone F Cuccurullo 2000 Oxidative stress and cardiovascular complications of diabetes: isoprostanes as new markers on an old paradigm Cardiovasc Res 47 475 488
-
(2000)
Cardiovasc Res
, vol.47
, pp. 475-488
-
-
Mezzetti, A.1
Cipollone, F.2
Cuccurullo, F.3
-
84
-
-
0032905015
-
In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin e supplementation
-
G Davi G Ciabattoni A Consoli A Mezzetti A Falco S Santarone 1999 In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation Circulation 99 224 229
-
(1999)
Circulation
, vol.99
, pp. 224-229
-
-
Davi, G.1
Ciabattoni, G.2
Consoli, A.3
Mezzetti, A.4
Falco, A.5
Santarone, S.6
-
85
-
-
0034647739
-
Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine
-
JM Onorato AJ Jenkins SR Thorpe JW Baynes 2000 Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine J Biol Chem 275 21177 21184
-
(2000)
J Biol Chem
, vol.275
, pp. 21177-21184
-
-
Onorato, J.M.1
Jenkins, A.J.2
Thorpe, S.R.3
Baynes, J.W.4
-
86
-
-
0036479252
-
A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation
-
PA Voziyan TO Metz JW Baynes BG Hudson 2002 A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation J Biol Chem 277 3397 3403
-
(2002)
J Biol Chem
, vol.277
, pp. 3397-3403
-
-
Voziyan, P.A.1
Metz, T.O.2
Baynes, J.W.3
Hudson, B.G.4
-
87
-
-
0022644227
-
Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking
-
M Brownlee H Vlassara A Kooney P Ulrich A Cerami 1986 Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking Science 232 1629 1632
-
(1986)
Science
, vol.232
, pp. 1629-1632
-
-
Brownlee, M.1
Vlassara, H.2
Kooney, A.3
Ulrich, P.4
Cerami, A.5
-
88
-
-
0026584035
-
Aminoguanidine ameliorates albuminuria in diabetic hypertensive rats
-
D Edelstein M Brownlee 1992 Aminoguanidine ameliorates albuminuria in diabetic hypertensive rats Diabetologia 35 96 97
-
(1992)
Diabetologia
, vol.35
, pp. 96-97
-
-
Edelstein, D.1
Brownlee, M.2
-
90
-
-
0028107538
-
Aminoguanidine inhibits the development of accelerated diabetic retinopathy in the spontaneous hypertensive rat
-
HP Hammes M Brownlee D Edelstein M Saleck S Martin K Federlin 1994 Aminoguanidine inhibits the development of accelerated diabetic retinopathy in the spontaneous hypertensive rat Diabetologia 37 32 35
-
(1994)
Diabetologia
, vol.37
, pp. 32-35
-
-
Hammes, H.P.1
Brownlee, M.2
Edelstein, D.3
Saleck, M.4
Martin, S.5
Federlin, K.6
-
91
-
-
13044292629
-
Effect of aminoguanidine on lipid-peroxidation in streptozotocin-induced diabetic rats
-
S Ihm J Hyung S Park J Ihm 1999 Effect of aminoguanidine on lipid-peroxidation in streptozotocin-induced diabetic rats Metabolism 48 1141 1145
-
(1999)
Metabolism
, vol.48
, pp. 1141-1145
-
-
Ihm, S.1
Hyung, J.2
Park, S.3
Ihm, J.4
-
94
-
-
0035498829
-
NADPH oxidase of neutrophils elevates o,o′-dityrosine cross-links in proteins and urine during inflammation
-
S Bhattacharjee S Pennathur J Byun J Crowley D Mueller J Gischler 2001 NADPH oxidase of neutrophils elevates o,o′-dityrosine cross-links in proteins and urine during inflammation Arch Biochem Biophys 395 69 77
-
(2001)
Arch Biochem Biophys
, vol.395
, pp. 69-77
-
-
Bhattacharjee, S.1
Pennathur, S.2
Byun, J.3
Crowley, J.4
Mueller, D.5
Gischler, J.6
-
95
-
-
0346731060
-
Amino acid and protein oxidation in cardiovascular disease
-
ML Brennan SL Hazen 2003 Amino acid and protein oxidation in cardiovascular disease Amino Acids 25 365 374
-
(2003)
Amino Acids
, vol.25
, pp. 365-374
-
-
Brennan, M.L.1
Hazen, S.L.2
-
96
-
-
0030803161
-
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: A sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation
-
SL Hazen JR Crowley DM Mueller JW Heinecke 1997 Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation Free Radic Biol Med 23 909 916
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 909-916
-
-
Hazen, S.L.1
Crowley, J.R.2
Mueller, D.M.3
Heinecke, J.W.4
-
97
-
-
9444291834
-
Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: Potential role of glucose-oxidized LDL
-
N Lamharzi CB Renard F Kramer S Pennathur JW Heinecke A Chait 2004 Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL Diabetes 53 3217 3225
-
(2004)
Diabetes
, vol.53
, pp. 3217-3225
-
-
Lamharzi, N.1
Renard, C.B.2
Kramer, F.3
Pennathur, S.4
Heinecke, J.W.5
Chait, A.6
-
98
-
-
33746669964
-
Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats
-
C Leeuwenburgh P Hansen A Shaish JO Holloszy JW Heinecke 1998 Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats Am J Physiol 274 R453 R461
-
(1998)
Am J Physiol
, vol.274
-
-
Leeuwenburgh, C.1
Hansen, P.2
Shaish, A.3
Holloszy, J.O.4
Heinecke, J.W.5
-
99
-
-
0032806289
-
Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine
-
C Leeuwenburgh PA Hansen JO Holloszy JW Heinecke 1999 Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine Free Radic Biol Med 27 186 192
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 186-192
-
-
Leeuwenburgh, C.1
Hansen, P.A.2
Holloszy, J.O.3
Heinecke, J.W.4
-
100
-
-
0032891777
-
Oxidized amino acids in the urine of aging rats: Potential markers for assessing oxidative stress in vivo
-
C Leeuwenburgh PA Hansen JO Holloszy JW Heinecke 1999 Oxidized amino acids in the urine of aging rats: potential markers for assessing oxidative stress in vivo Am J Physiol 276 R128 R135
-
(1999)
Am J Physiol
, vol.276
-
-
Leeuwenburgh, C.1
Hansen, P.A.2
Holloszy, J.O.3
Heinecke, J.W.4
-
101
-
-
0031021944
-
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques
-
C Leeuwenburgh JE Rasmussen FF Hsu DM Mueller S Pennathur JW Heinecke 1997 Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques J Biol Chem 272 3520 3526
-
(1997)
J Biol Chem
, vol.272
, pp. 3520-3526
-
-
Leeuwenburgh, C.1
Rasmussen, J.E.2
Hsu, F.F.3
Mueller, D.M.4
Pennathur, S.5
Heinecke, J.W.6
-
103
-
-
0033521095
-
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o′-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease
-
S Pennathur V Jackson-Lewis S Przedborski JW Heinecke 1999 Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o′-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease J Biol Chem 274 34621 3468
-
(1999)
J Biol Chem
, vol.274
, pp. 34621-3468
-
-
Pennathur, S.1
Jackson-Lewis, V.2
Przedborski, S.3
Heinecke, J.W.4
-
104
-
-
4344577056
-
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease
-
L Zheng B Nukuna ML Brennan M Sun M Goormastic M Settle 2004 Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease J Clin Invest 114 529 541
-
(2004)
J Clin Invest
, vol.114
, pp. 529-541
-
-
Zheng, L.1
Nukuna, B.2
Brennan, M.L.3
Sun, M.4
Goormastic, M.5
Settle, M.6
-
105
-
-
0034933340
-
Early cellular and molecular changes induced by diabetes in the retina
-
M Lorenzi C Gerhardinger 2001 Early cellular and molecular changes induced by diabetes in the retina Diabetologia 44 791 804
-
(2001)
Diabetologia
, vol.44
, pp. 791-804
-
-
Lorenzi, M.1
Gerhardinger, C.2
-
106
-
-
0942279561
-
Plasminogen kringle 5 reduces vascular leakage in the retina in rat models of oxygen-induced retinopathy and diabetes
-
SX Zhang J Sima C Shao J Fant Y Chen B Rohrer 2004 Plasminogen kringle 5 reduces vascular leakage in the retina in rat models of oxygen-induced retinopathy and diabetes Diabetologia 47 124 131
-
(2004)
Diabetologia
, vol.47
, pp. 124-131
-
-
Zhang, S.X.1
Sima, J.2
Shao, C.3
Fant, J.4
Chen, Y.5
Rohrer, B.6
-
107
-
-
3142624781
-
Inflammatory and oxidative markers in atherosclerosis: Relationship to outcome
-
MH Shishehbor SL Hazen 2004 Inflammatory and oxidative markers in atherosclerosis: relationship to outcome Curr Atheroscler Rep 6 243 250
-
(2004)
Curr Atheroscler Rep
, vol.6
, pp. 243-250
-
-
Shishehbor, M.H.1
Hazen, S.L.2
|