NADPH oxidase of neutrophils elevates o, o′-dityrosine cross-links in proteins and urine during inflammation

Archives of Biochemistry and Biophysics

Volumn 395, Issue 1, 2001, Pages 69-77

  Bhattacharjee, Suchandra ^a   Pennathur, Subramaniam ^a   Byun, Jaeman ^a   Crowley, Jan ^a   Mueller, Dianne ^a   Gischler, Jennifer ^a   Hotchkiss, Richard S ^a   Heinecke, Jay W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic granulomatous disease; Myeloperoxidase; oxidative stress; oxidized amino acid; peroxynitrite; superoxide

Indexed keywords

2,2' DITYROSINE; AMINO ACID; MYELOPEROXIDASE; OXIDIZING AGENT; PEROXYNITRITE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; GRANULOMATOSIS; HUMAN; IN VIVO STUDY; INFLAMMATION; ISOTOPE LABELING; MASS SPECTROMETRY; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN CONTENT; QUANTITATIVE ASSAY; SIGNAL TRANSDUCTION; TISSUE INJURY; URINALYSIS;

ANIMALIA;

EID: 0035498829     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.2001.2557     Document Type: Article

References (47)

1. Oxygen metabolism and the toxic properties of phagocytes
2. Role of oxidative stress in development of complications in diabetes
3. The role of oxidized lipoproteins in atherogenesis
4. Protein oxidation and aging
5. Oxidants, antioxidants and the degenerative diseases of aging
6. Isoprostanes: Potential markers of oxidant stress in atherothrombotic disease
7. The isoprostanes current knowledge and directions for future research
8. Protein modification by oxidants and the role of proteolytic enzymes
9. Biochemistry and pathology of radical-mediated protein oxidation
10. Mass spectrometric quantification of amino acid oxidation products in proteins: Insights into pathways that promote LDL oxidation in the human artery wall
11. Stable markers of oxidant damage to proteins and their application in the study of human disease
12. Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
13. Protein damage and degradation by oxygen radicals. II. Modification of amino acids
14. Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages
15. Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins
16. Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric-oxide dependent toxicity
17. Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation
18. Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques
19. Oxidized amino acids in the urine of aging rats
20. Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
21. Immunochemical detection of protein dityrosine in atherosclerotic lesion of apo-E-deficient mice using a novel monoclonal antibody
22. Myeloperoxidase and protein oxidation in cystic fibrosis
23. Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o, o′-dityrosine in brain tissue of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease
24. Dityrosine cross-linking promotes formation of stable alpha-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
25. Biological defense mechanism: The production by leukocytes of superoxide, a potential bactericidal agent
26. Leukocytic oxygen activation and microbicidal oxidative toxins
27. NADPH oxidase
28. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
29. Quality control in the endoplasmic reticulum: Lessons from hereditary myeloperoxidase deficiency
30. Dityosine and tyrosine oxidation products are endogenous markers for the selective proteolysis of oxidatively modified red blood cell hemoglobin by the 19 S proteosome
31. Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine
32. Dietary antioxidants and assessment of oxidative stress
33. Dispensable and indispensable amino acids for humans
34. Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: Sensitive and quantitative assays for oxidized amino acids in proteins and tissues
35. Human phagocytes employ the myeloperoxidase-hydrogen peroxide system to synthesize dityrosine, trityrosine, pulcherosine, and isodityrosine by a tyrosyl radical-dependent pathway
36. Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes produces 5-chlorocytosine in bacterial RNA
37. Endogenous protein phosphorylation by resting and activated human neutrophils
38. Mass spectrometry and the age of the proteome
39. Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly
40. A hydroxyl radical-like species oxidizes Cynomolgus monkey artery wall proteins early in diabetic vascular disease
41. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
42. Dityrosine formation outcompetes tyrosine nitration at low steady-state concentrations of peroxynitrite. Implications for tyrosine modification by nitric oxide/superoxide in vivo
43. Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase and horseradish peroxidase
44. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
45. Apoptosis in resolution of inflammation