Pivotal role of angiotensin II receptor subtype 1A in the development of two-kidney, one-clip hypertension: Study in angiotensin II receptor subtype 1A knockout mice

Journal of Hypertension

Volumn 26, Issue 7, 2008, Pages 1379-1389

  Červenka, Luděk ^a,b,c   Vaněčková, Ivana ^a,b   Husková, Zuzana ^a,b   Vaňourková, Zdenka ^a,b   Erbanová, Michaela ^a   Thumová, Monika ^a   Škaroupková, Petra ^a   Opočenský, Martin ^a   Malý, Jan ^a   Chábová, Věra Čertíková ^c   Tesař, Vladimír ^c   Bürgelová, Marcela ^d   Viklický, Ondřej ^d   Teplan, Vladimír ^d   Želízko, Michal ^a   Kramer, Herbert J ^e   Navar, L Gabriel ^f  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b Center for Cardiovascular Research   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d Charles University ^*  (Czech Republic)

^e UNIVERSITY OF BONN   (Germany)

^f TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin II receptor subtype 1A knockout mice; Angiotensin II receptor subtype 1B; Angiotensin II type 2 receptor; Nitric oxide synthase; one clip Goldblatt hypertension; Plasma and kidney angiotensin II levels; Reninangiotensin system; Two kidney

Indexed keywords

ANGIOTENSIN 1A RECEPTOR; ANGIOTENSIN 1B RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ARGININE METHYL ESTER; NICOTINOYLTYROSYL(N BENZYLOXYCARBONYLARGINYL)LYSYLHISTIDYLPROLYLISOLEUCINE; NITRIC OXIDE SYNTHASE; SODIUM CHLORIDE; ANGIOTENSIN 1 RECEPTOR;

ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERTENSION; INFUSION; KIDNEY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RENAL ARTERY; TELEMETRY; VASODILATATION; ANIMAL; DISEASE MODEL; GENETICS; LIGATION; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ANIMALS; DISEASE MODELS, ANIMAL; HYPERTENSION; LIGATION; MALE; MICE; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RENAL ARTERY; RENIN-ANGIOTENSIN SYSTEM;

EID: 54449089586     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e3282fe6eaa     Document Type: Article

References (45)

1. Navar LG, Zou L, Von Thun A, Wang CT, Imig JD, Mitchell KD. Unraveling the mystery of Goldblatt hypertension. News Physiol Sci 1998; 13:170-176.
2. Cervenka L, Wang CT, Mitchell KD, Navar LG. Proximal tubular angiotensin II levels and renal functional responses to AT1. receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats. Hypertension 1999;33:102-107.
3. Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal renin- angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59:251-287.
4. Ingert C, Grima M, Coquard C, Barthelmers M, Imbs JL. Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats. Am J Physiol 2002; 283:F1003-F1010.
5. Navar LG, Nishiyama A. Why are angiotensin concentrations so high in the kidney? Curr Opin Nephrol Hypertens 2004; 13:107-115.
6. Sasamura H, Hein L, Krieger J, Prattt R, Kobilka B, Dzau V. Cloning characterization and expression of 2. angiotensin receptor (AT-1) isoforms from the mouse genome. Biochem Biophys Res Commun 1992; 185:253-259.
7. Crowley SD, Tharaux PL, Audoly LP, Coffman TM. Exploring type I angiotensin (AT1) receptor functions through gene targeting. Acta Physiol Scand 2004; 181.:561-570.
8. 1A receptor in the development of 2K1C hypertension. Hypertension 2002; 40:735-741.
9. 1B receptors in blood pressure regulation. Am J Physiol 1997; 272:F515-F520.
10. 1A receptor-deficient mice. Hypertension 1998;31.:1171-1177.
11. Ruan X, Purdy KE, Oliverio MI, Coffman TM, Arendshorst WJ. Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice. J Am Soc Nephrol 1999; 10:S202-S207.
12. Harrison-Bernard LM, Cook AK, Oliverio MI, Coffman TM. Renal segmental microvascular responses to ANG II in AT1Areceptor null mice. Am J Physio 2003; 284:F538-F545.
13. 1A eceptor-deficient mice. Am J Physiol 2007; 293:F586-F593.
14. Carey RM, Howell NL, Jin XH, Siragy HM. Angiotensin type 2. receptor- mediated hypotension in angiotensin type-1. receptor-blocked rats. Hypertension 2001; 38:1272-1277.
15. Widdop RE, Matrougui K, Levy BI, Henrion D. AT2. receptor-mediated relaxation is preserved after long-term AT1. receptor blockade. Hypertension 2002; 40:516-520.
16. 1 receptor blockade in conscious SHR. Br J Pharmacol 2004;142:821-830.
17. Padia SH, Howell NL, Siragy HM, Carey RM. Renal angiotensin type 2. receptors mediate natriuresis via angiotensin III in the angiotensin II type 1. receptor-blocked rat. Hypertension 2006; 47:537-544.
18. Sigmon DH, Beierwaltes WH. Renal nitric oxideand angiotensin II interaction in renovascular hypertension. Hypertension 1993; 22:237-242.
19. Chin SY, Wang CT, Majid DSA, Navar LG. Renoprotective effects of nitric oxide in angiotensin II-induced hypertension in the rat. Am J Physiol 1998;274:F876-F882.
20. Navar LG, Ichihara A, Chin SY, Imig JD. Nitric oxide-angiotensin II interactions in angiotensin II-dependent hypertension. Acta Physiol Scand 2000; 168:139-147.
21. Mitchell KD, Botros FT, Navar LG. Intrarenal renin-angiotensin system and counteracting protective mechanisms in angiotensin II-dependent hypertension. Acta Physiol Hung 2007; 94:31-48.
22. Hitomi H, Kiyomoto H, Nishiyama A. Angiotensin II and oxidative stress. Curr Opin Cardiol 2007; 22:311-315.
23. Reckelhoff JF, Romero JC. Role of oxidative stress in angiotensin-induced hypertension. Am J Physiol 2003; 284:R893-R912.
24. Kawada N, Imai E, Karber A, Welch W, Wilcox CS. A mouse model of angiotensin II slow pressor response: role of oxidative stress. J Am Soc Nephrol 2002; 13:2860-2868.
25. Oliverio MI, Best CF, Smithies O, Coffman TM. Regulation of sodium balance and blood pressure by the AT1A receptor for angiotensin II. Hypertension 2000; 35:550-554.
26. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurements in humans and experimental animals. Part 2: blood pressure measurements in experimental animals. Hypertension 2005; 45:299-310.
27. Whitesall SE, Hoff JB, Vollmer AP, D'Alecy LG. Comparison of simultaneous measurements of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods. Am J Physiol 2004; 286:H2408- H2415.
28. 2 receptor. J Hypertens 2003;21.:1531-1538.
29. Husková Z, Kramer HJ, Thumová M, Vaňourková Z, Bürgelová M, Teplan V, Červenka L. Effects of anaesthesia on plasma and kidney ANG II levels in normotensive and ANG II-dependent hypertensive rats. Kidney Blood Press Res 2006; 29:74-83.
30. Fox J, Guan S, Hymel AA, Navar LG. Dietary Na and ACE inhibition effects on renal tissue angiotensin I and II and ACE activity in rats. Am J Physiol 1992; 262:F902-F909.
31. Navar LG, Lewis L, Hymel A, Braam B, Mitchell KD. Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats. J Am Soc Nephrol 1994; 5:1153-1158.
32. Kopkan L, Kramer HJ, Huskova Z, Vaňourková Z, Škaroupková P, Thumová M, et al. The role of intrarenal angiotensin II in the development of hypertension in Ren-2. transgenic rats. JHypertens 2005; 23:1531-1539.
33. 1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2. transgenic rats with inducible hypertension. J Hypertens 2006; 24:2465-2472.
34. Huskova Z, Kramer HJ, Vaňourková Z, Thumová M, Malý J, Opočenský M, et al. Effects of dietary salt load and salt depletion on the course of hypertension and angiotensin II levels in male and female heterozygous Ren-2. transgenic rats. Kidney Blood Press Res 2007; 30:45-55.
35. 2receptor ligands CGP 42112. and PD 123319. after blockade ofthe renin-angiotensin system. EurJPharmacol1994; 259:27-36.
36. Harrison-Bernard LM, Monjure CJ, Bivona BJ. Efferent arterioles exclusively express the subtype 1A angiotensin receptor: functional insights from genetic mouse models. Am J Physiol 2006; 290:F1177-F1186.
37. Park S, Bivona BJ, Harrison-Bernard LM. Compromised renal microvascular reactivity of angiotensin type 1. double null mice. Am J Physiol 2007; 293:F60-F67.
38. Swafford AN, Harrison-Bernard LM, Dick GM. Knockout mice reveal that the angiotensin II type 1B receptor links to smooth muscle contraction. Am J Hypertens 2007; 20:335-337.
39. Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, et al. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci USA 2006; 103:1. 7985-17990.
40. Ruiz-Ortega M, Esteban V, Ruperez M, Sanchez-Lopez E, Rodriguez-Vita J, Carjal G, Egido J. Renal and vascular hypertension-induced inflammation: role of angiotensin II. Curr Opin Nephrol Hypertens 2006; 15:159-166.
41. Fleming I, Kohlstedt K, Busse R. The tissue renin-angiotensin system and intracellular signaling. Curr Opin Nephrol Hypertens 2006; 15:8-13.
42. Siragy HM, Xue C, Abadir P, Carey RM. Angiotensin subtype-2. receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension 2005; 45:133-137.
43. Chin SY, Pandey KN, Shi SJ, Kobori H, Moreno C, Navar LG. Increased activity and protein expression of calcium-dependent nitric oxide synthases in the renal cortex of angiotensin II-infused hypertensive rats. Am J Physiol 1999; 277:F797-F804.
44. Patzak A, Lai EY, Mrowka R, Steege A, Persson PB, Persson EG. AT receptors mediate angiotensin II-induced release of nitric oxide in afferent arterioles. Kidney Int 2004; 66:1949-1958.
45. Hiyoshi H, Yayama K, Takano M, Okamoto H. Angiotensin type 2. receptor- mediated phosphorylation of eNOS in the aortas of mice with 2-kidney, 1-clip hypertension. Hypertension 2005; 45:967-973.