메뉴 건너뛰기




Volumn 5, Issue , 2004, Pages 189-218

Genetics of atherosclerosis

Author keywords

Atherosclerosis; Cardiovascular disease; Lipoproteins; Myocardial infarction; Stroke

Indexed keywords

ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; FAMILIAL HYPERCHOLESTEROLEMIA; FAMILY HISTORY; GENETIC EPIDEMIOLOGY; GENETICS; HEART INFARCTION; HEREDITY; HUMAN; NONHUMAN; REVIEW; RISK FACTOR; STROKE;

EID: 5444244817     PISSN: 15278204     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genom.5.061903.175930     Document Type: Review
Times cited : (262)

References (106)
  • 1
    • 0032958470 scopus 로고    scopus 로고
    • Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
    • Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, et al. 1999. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat. Genet. 21:76-83
    • (1999) Nat. Genet. , vol.21 , pp. 76-83
    • Aitman, T.J.1    Glazier, A.M.2    Wallace, C.A.3    Cooper, L.D.4    Norsworthy, P.J.5
  • 3
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. 2000. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat. Genet. 26:76-80
    • (2000) Nat. Genet. , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3    Lindgren, C.M.4    Vohl, M.C.5
  • 4
    • 0000874922 scopus 로고
    • Evidence for a monoclonal origin of human atherosclerotic plaques
    • Benditt EP, Benditt JM. 1973. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc. Natl. Acad. Sci. USA 70:1753-56
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 1753-1756
    • Benditt, E.P.1    Benditt, J.M.2
  • 5
    • 0028903234 scopus 로고
    • Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques
    • Bennett MR, Evan GI, Schwartz SM. 1995. Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques. J. Clin. Invest. 95:2266-74
    • (1995) J. Clin. Invest. , vol.95 , pp. 2266-2274
    • Bennett, M.R.1    Evan, G.I.2    Schwartz, S.M.3
  • 6
    • 0024307239 scopus 로고
    • Impact of medical genetics on research and practices in the area of cardiovascular disease
    • Berg K. 1989. Impact of medical genetics on research and practices in the area of cardiovascular disease. Clin. Genet. 36:299-312
    • (1989) Clin. Genet. , vol.36 , pp. 299-312
    • Berg, K.1
  • 7
    • 0002294033 scopus 로고
    • Lp(a) lipoprotein: An important genetic risk factor for atherosclerosis
    • ed. AJ Lusis, JI Rotter, RS Sparkes. Basel, Switzerland: Karger
    • Berg K. 1993. Lp(a) lipoprotein: an important genetic risk factor for atherosclerosis. In Molecular Genetics of Coronary Artery Disease, ed. AJ Lusis, JI Rotter, RS Sparkes, pp. 189-207. Basel, Switzerland: Karger
    • (1993) Molecular Genetics of Coronary Artery Disease , pp. 189-207
    • Berg, K.1
  • 8
    • 0032813809 scopus 로고    scopus 로고
    • The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
    • Bodzioch M, Orso E, Klucken J, Langmann T, Bottcher A, et al. 1999. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat. Genet. 22:347-51
    • (1999) Nat. Genet. , vol.22 , pp. 347-351
    • Bodzioch, M.1    Orso, E.2    Klucken, J.3    Langmann, T.4    Bottcher, A.5
  • 9
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH. 1992. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J. Clin. Invest. 90:52-60
    • (1992) J. Clin. Invest. , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 10
    • 0037373275 scopus 로고    scopus 로고
    • Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
    • Botstein D, Risch N. 2003. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat. Genet. 33(Suppl.):228-37
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 228-237
    • Botstein, D.1    Risch, N.2
  • 11
    • 18544372620 scopus 로고    scopus 로고
    • A comprehensive linkage analysis for myocardial infarction and its related risk factors
    • Broeckel U, Hengstenberg C, Mayer B, Holmer S, Martin LJ, et al. 2002. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat. Genet. 30:210-14
    • (2002) Nat. Genet. , vol.30 , pp. 210-214
    • Broeckel, U.1    Hengstenberg, C.2    Mayer, B.3    Holmer, S.4    Martin, L.J.5
  • 12
    • 0036395179 scopus 로고    scopus 로고
    • Genetic disorders associated with ATP binding cassette cholesterol transporters
    • Burris TP, Eacho PI, Cao G. 2002. Genetic disorders associated with ATP binding cassette cholesterol transporters. Mol. Genet. Metab. 77:13-20
    • (2002) Mol. Genet. Metab. , vol.77 , pp. 13-20
    • Burris, T.P.1    Eacho, P.I.2    Cao, G.3
  • 13
    • 0026675062 scopus 로고
    • Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
    • Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, et al. 1992. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359:641-44
    • (1992) Nature , vol.359 , pp. 641-644
    • Cambien, F.1    Poirier, O.2    Lecerf, L.3    Evans, A.4    Cambou, J.P.5
  • 14
    • 0029153057 scopus 로고
    • Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans
    • Caulfield M, Lavender P, Newell-Price J, Farrall M, Kamdar S, et al. 1995. Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. J. Clin. Invest. 96:687-92
    • (1995) J. Clin. Invest. , vol.96 , pp. 687-692
    • Caulfield, M.1    Lavender, P.2    Newell-Price, J.3    Farrall, M.4    Kamdar, S.5
  • 16
    • 0030069735 scopus 로고    scopus 로고
    • Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: Effects on LDL-cholesterol and apolipoproteins B and C-III
    • Dallinga-Thie GM, Bu XD, van Linde-Sibenius Trip M, Rotter JI, Lusis AJ, de Bruin TW. 1996. Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoproteins B and C-III. J. Lipid Res. 37:136-47
    • (1996) J. Lipid Res. , vol.37 , pp. 136-147
    • Dallinga-Thie, G.M.1    Bu, X.D.2    Van Linde-Sibenius Trip, M.3    Rotter, J.I.4    Lusis, A.J.5    De Bruin, T.W.6
  • 18
    • 0028854118 scopus 로고
    • Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus
    • DeMeester CA, Bu X, Gray RJ, Lusis AJ, Rotter JI. 1995. Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus. Am. J. Hum. Genet. 56:287-93
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 287-293
    • DeMeester, C.A.1    Bu, X.2    Gray, R.J.3    Lusis, A.J.4    Rotter, J.I.5
  • 19
    • 0141618462 scopus 로고    scopus 로고
    • Genetics of common polygenic stroke
    • Dominiczak AF, McBride MW. 2003. Genetics of common polygenic stroke. Nat. Genet. 35:116-17
    • (2003) Nat. Genet. , vol.35 , pp. 116-117
    • Dominiczak, A.F.1    McBride, M.W.2
  • 20
    • 0033059209 scopus 로고    scopus 로고
    • Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment
    • Drazen JM, Yandava CN, Dube L, Szczerback N, Hippensteel R, et al. 1999. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat. Genet. 22:168-70
    • (1999) Nat. Genet. , vol.22 , pp. 168-170
    • Drazen, J.M.1    Yandava, C.N.2    Dube, L.3    Szczerback, N.4    Hippensteel, R.5
  • 21
    • 0347418277 scopus 로고    scopus 로고
    • Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid and atherosclerosis in humans: The Los Angeles Heart Study
    • Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, et al. 2004. Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid and atherosclerosis in humans: The Los Angeles Heart Study. N. Engl. J. Med. 350:29-37
    • (2004) N. Engl. J. Med. , vol.350 , pp. 29-37
    • Dwyer, J.H.1    Allayee, H.2    Dwyer, K.M.3    Fan, J.4    Wu, H.5
  • 22
    • 0032910599 scopus 로고    scopus 로고
    • A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians
    • Elbein SC, Hoffman MD, Teng K, Leppert MF, Hasstedt SJ. 1999. A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians. Diabetes 48:1175-82
    • (1999) Diabetes , vol.48 , pp. 1175-1182
    • Elbein, S.C.1    Hoffman, M.D.2    Teng, K.3    Leppert, M.F.4    Hasstedt, S.J.5
  • 23
    • 0027486088 scopus 로고
    • Relationship between insulin resistance and coronary heart disease in diabetes mellitus and the general population: A critical appraisal
    • Elliott TG, Viberti G. 1993. Relationship between insulin resistance and coronary heart disease in diabetes mellitus and the general population: a critical appraisal. Baillieres Clin. Endocrinol. Metab. 7:1079-103
    • (1993) Baillieres Clin. Endocrinol. Metab. , vol.7 , pp. 1079-1103
    • Elliott, T.G.1    Viberti, G.2
  • 25
    • 18244398717 scopus 로고    scopus 로고
    • A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27
    • Francke S, Manraj M, Lacquemant C, Lecoeur C, Lepretre F, et al. 2001. A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27. Hum. Mol. Genet. 10:2751-65
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2751-2765
    • Francke, S.1    Manraj, M.2    Lacquemant, C.3    Lecoeur, C.4    Lepretre, F.5
  • 27
  • 28
    • 0000710395 scopus 로고
    • Familial hypercholesterolemia
    • ed. CR Scriver, AL Beaudet, WS Sly, D Valle. New York: McGraw Hill
    • Goldstein JL, Hobbs HH, Brown MS. 1995. Familial hypercholesterolemia. In The Metabolic Basis of Inherited Disease, ed. CR Scriver, AL Beaudet, WS Sly, D Valle, pp. 1267-82. New York: McGraw Hill
    • (1995) The Metabolic Basis of Inherited Disease , pp. 1267-1282
    • Goldstein, J.L.1    Hobbs, H.H.2    Brown, M.S.3
  • 30
    • 0027232397 scopus 로고
    • The hemostatic system and coronary heart disease
    • Hamsten A. 1993. The hemostatic system and coronary heart disease. Thromb. Res. 70:1-38
    • (1993) Thromb. Res. , vol.70 , pp. 1-38
    • Hamsten, A.1
  • 32
    • 0032231322 scopus 로고    scopus 로고
    • An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
    • Hanson RL, Ehm MG, Pettitt DJ, Prochazka M, Thompson DB, et al. 1998. An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am. J. Hum. Genet. 63:1130-38
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 1130-1138
    • Hanson, R.L.1    Ehm, M.G.2    Pettitt, D.J.3    Prochazka, M.4    Thompson, D.B.5
  • 34
  • 35
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, et al. 2000. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat. Genet. 26:163-75
    • (2000) Nat. Genet. , vol.26 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.J.3    Li, X.4    Orho-Melander, M.5
  • 36
    • 0141723641 scopus 로고    scopus 로고
    • Introduction: New insight into understanding the relation of type 2 diabetes mellitus, insulin resistance, and cardiovascular disease
    • Hsueh WA. 2003. Introduction: new insight into understanding the relation of type 2 diabetes mellitus, insulin resistance, and cardiovascular disease. Am. J. Cardiol. 92:1J-2J
    • (2003) Am. J. Cardiol. , vol.92
    • Hsueh, W.A.1
  • 37
    • 0026498483 scopus 로고
    • The study of gene-environment interactions that influence thrombosis and fibrinolysis. Genetic variation at the loci for factor VII and plasminogen activator inhibitor-1
    • Humphries SE, Lane A, Dawson S, Green FR. 1992. The study of gene-environment interactions that influence thrombosis and fibrinolysis. Genetic variation at the loci for factor VII and plasminogen activator inhibitor-1. Arch. Pathol. Lab. Med. 116:1322-29
    • (1992) Arch. Pathol. Lab. Med. , vol.116 , pp. 1322-1329
    • Humphries, S.E.1    Lane, A.2    Dawson, S.3    Green, F.R.4
  • 38
    • 0029927125 scopus 로고    scopus 로고
    • A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice
    • Ivandic BT, Qiao JH, Machleder D, Liao F, Drake TA, Lusis AJ. 1996. A locus on chromosome 7 determines myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice. Proc. Natl. Acad. Sci. USA 93:5483-88
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5483-5488
    • Ivandic, B.T.1    Qiao, J.H.2    Machleder, D.3    Liao, F.4    Drake, T.A.5    Lusis, A.J.6
  • 39
    • 0036705558 scopus 로고    scopus 로고
    • Major gene evidence after MTHFR-segregation analysis of serum homocysteine in families of patients undergoing coronary arteriography
    • Jee SH, Song KS, Shim WH, Kim HK, Sun I, et al. 2002. Major gene evidence after MTHFR-segregation analysis of serum homocysteine in families of patients undergoing coronary arteriography. Hum. Genet. 111:128-35
    • (2002) Hum. Genet. , vol.111 , pp. 128-135
    • Jee, S.H.1    Song, K.S.2    Shim, W.H.3    Kim, H.K.4    Sun, I.5
  • 40
    • 0030845876 scopus 로고    scopus 로고
    • Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus
    • Jeffs B, Clark JS, Anderson NH, Gratton J, Brosnan MJ, et al. 1997. Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat. Genet. 16:364-67
    • (1997) Nat. Genet. , vol.16 , pp. 364-367
    • Jeffs, B.1    Clark, J.S.2    Anderson, N.H.3    Gratton, J.4    Brosnan, M.J.5
  • 41
    • 0027421353 scopus 로고
    • Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
    • Rang SS, Passen EL, Ruggie N, Wong PW, Sora H. 1993. Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation 88:1463-69
    • (1993) Circulation , vol.88 , pp. 1463-1469
    • Rang, S.S.1    Passen, E.L.2    Ruggie, N.3    Wong, P.W.4    Sora, H.5
  • 42
    • 0027230435 scopus 로고
    • Intimai thickening of the coronary arteries in infants in relation to family history of coronary artery disease
    • Kaprio J, Norio R, Pesonen E, Sama S. 1993. Intimai thickening of the coronary arteries in infants in relation to family history of coronary artery disease. Circulation 87:1960-68
    • (1993) Circulation , vol.87 , pp. 1960-1968
    • Kaprio, J.1    Norio, R.2    Pesonen, E.3    Sama, S.4
  • 48
    • 0028047925 scopus 로고
    • Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice
    • Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. 1994. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J. Clin. Invest. 94:877-84
    • (1994) J. Clin. Invest. , vol.94 , pp. 877-884
    • Liao, F.1    Andalibi, A.2    Qiao, J.H.3    Allayee, H.4    Fogelman, A.M.5    Lusis, A.J.6
  • 49
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton RP, Gharavi AG, Geller DS. 2001. Molecular mechanisms of human hypertension. Cell 104:545-56
    • (2001) Cell. , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 50
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. 2000. Atherosclerosis. Nature 407:233-41
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 51
    • 0242334049 scopus 로고    scopus 로고
    • Genetic factors in cardiovascular disease. 10 Questions
    • Lusis AJ. 2003. Genetic factors in cardiovascular disease. 10 questions. Trends Cardiovasc. Med. 13:309-16
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 309-316
    • Lusis, A.J.1
  • 53
    • 0036078307 scopus 로고    scopus 로고
    • Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression
    • Lutgens E, Gijbels M, Smook M, Heeringa P, Gotwals P, et al. 2002. Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression. Arterioscler. Thromb. Vasc. Biol. 22:975-82
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 975-982
    • Lutgens, E.1    Gijbels, M.2    Smook, M.3    Heeringa, P.4    Gotwals, P.5
  • 54
    • 0027537768 scopus 로고
    • Glycation and oxidation: A role in the pathogenesis of atherosclerosis
    • Lyons TJ. 1993. Glycation and oxidation: a role in the pathogenesis of atherosclerosis. Am. J. Cardiol. 71:26B-31B
    • (1993) Am. J. Cardiol. , vol.71
    • Lyons, T.J.1
  • 55
    • 0029806746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
    • Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, et al. 1996. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 94:2410-16
    • (1996) Circulation , vol.94 , pp. 2410-2416
    • Ma, J.1    Stampfer, M.J.2    Hennekens, C.H.3    Frosst, P.4    Selhub, J.5
  • 56
    • 0037178728 scopus 로고    scopus 로고
    • Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice
    • Mehrabian M, Allayee H, Wong J, Shi W, Wang XP, et al. 2002. Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circ. Res. 91:120-26
    • (2002) Circ. Res. , vol.91 , pp. 120-126
    • Mehrabian, M.1    Allayee, H.2    Wong, J.3    Shi, W.4    Wang, X.P.5
  • 57
    • 0036396687 scopus 로고    scopus 로고
    • The role of transcription factors in maturity-onset diabetes of the young
    • Mitchell SM, Frayling TM. 2002. The role of transcription factors in maturity-onset diabetes of the young. Mol. Genet. Metab. 77:35-43
    • (2002) Mol. Genet. Metab. , vol.77 , pp. 35-43
    • Mitchell, S.M.1    Frayling, T.M.2
  • 58
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, et al. 2003. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34:267-73
    • (2003) Nat. Genet. , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3    Subramanian, A.4    Sihag, S.5
  • 59
    • 0026702128 scopus 로고
    • Nutrition and genetic susceptibility to common diseases
    • Motulsky AG. 1992. Nutrition and genetic susceptibility to common diseases. Am. J. Clin. Nutr. 55:12448-458
    • (1992) Am. J. Clin. Nutr. , vol.55 , pp. 12448-12458
    • Motulsky, A.G.1
  • 60
    • 0346452343 scopus 로고    scopus 로고
    • Genetics of coronary atherosclerosis
    • ed. RA King, JI Rotter, AG Motulsky. New York: Oxford Univ. Press
    • Motulsky AG, Brunzell JD. 2003. Genetics of coronary atherosclerosis. In The Genetic Basis of Common Disease, 2nd Edition, ed. RA King, JI Rotter, AG Motulsky, pp. 105-26. New York: Oxford Univ. Press
    • (2003) The Genetic Basis of Common Disease, 2nd Edition , pp. 105-126
    • Motulsky, A.G.1    Brunzell, J.D.2
  • 61
    • 0016685859 scopus 로고
    • Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan. Hawaii and California: Distribution of biochemical risk factors
    • Nichaman MZ, Hamilton HB, Kagan A, Grier T, Sacks T, Syme SL. 1975. Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: distribution of biochemical risk factors. Am. J. Epidemiol. 102:491-501
    • (1975) Am. J. Epidemiol. , vol.102 , pp. 491-501
    • Nichaman, M.Z.1    Hamilton, H.B.2    Kagan, A.3    Grier, T.4    Sacks, T.5    Syme, S.L.6
  • 62
    • 0029145667 scopus 로고
    • Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians
    • Norman RA, Bogardus C, Ravussin E. 1995. Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians. J. Clin. Invest. 96:158-62
    • (1995) J. Clin. Invest. , vol.96 , pp. 158-162
    • Norman, R.A.1    Bogardus, C.2    Ravussin, E.3
  • 63
    • 18744407845 scopus 로고    scopus 로고
    • Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
    • Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, et al. 2002. Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat. Genet. 32:650-54
    • (2002) Nat. Genet. , vol.32 , pp. 650-654
    • Ozaki, K.1    Ohnishi, Y.2    Iida, A.3    Sekine, A.4    Yamada, R.5
  • 64
    • 0033658950 scopus 로고    scopus 로고
    • Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland
    • Pajukanta P, Cargill M, Viitanen L, Nuotio I, Kareinen A, et al. 2000. Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. Am. J. Hum. Genet. 67:1481-93
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1481-1493
    • Pajukanta, P.1    Cargill, M.2    Viitanen, L.3    Nuotio, I.4    Kareinen, A.5
  • 65
    • 12144287541 scopus 로고    scopus 로고
    • Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
    • Pajukanta P, Lilja HE, Sinsheimer JS, Cantor RM, Lusis AJ, et al. 2004. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nat. Genet. 36:371-76
    • (2004) Nat. Genet. , vol.36 , pp. 371-376
    • Pajukanta, P.1    Lilja, H.E.2    Sinsheimer, J.S.3    Cantor, R.M.4    Lusis, A.J.5
  • 67
    • 0035941029 scopus 로고    scopus 로고
    • Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
    • Patil N, Berno AJ, Hinds DA, Barrett WA, Doshi JM, et al. 2001. Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 294:1719-23
    • (2001) Science , vol.294 , pp. 1719-1723
    • Patil, N.1    Berno, A.J.2    Hinds, D.A.3    Barrett, W.A.4    Doshi, J.M.5
  • 68
    • 0030969425 scopus 로고    scopus 로고
    • Role of macrophage colony-stimulating factor in atherosclerosis: Studies of osteopetrotic mice
    • Qiao JH, Tripathi J, Mishra NK, Cai Y, Tripathi S, et al. 1997. Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice. Am. J. Pathol. 150:1687-99
    • (1997) Am. J. Pathol. , vol.150 , pp. 1687-1699
    • Qiao, J.H.1    Tripathi, J.2    Mishra, N.K.3    Cai, Y.4    Tripathi, S.5
  • 69
    • 0028105909 scopus 로고
    • Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification
    • Qiao JH, Xie PZ, Fishbein MC, Kreuzer J, Drake TA, et al. 1994. Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. Arterioscler. Thromb. 14:1480-97
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 1480-1497
    • Qiao, J.H.1    Xie, P.Z.2    Fishbein, M.C.3    Kreuzer, J.4    Drake, T.A.5
  • 70
    • 0142228253 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis
    • Randi AM, Biguzzi E, Falciani F, Merlini P, Blakemore S, et al. 2003. Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis. J. Thromb. Haemost. 1:829-35
    • (2003) J. Thromb. Haemost. , vol.1 , pp. 829-835
    • Randi, A.M.1    Biguzzi, E.2    Falciani, F.3    Merlini, P.4    Blakemore, S.5
  • 71
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM. 1988. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37:1595-607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 72
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES. 2001. On the allelic spectrum of human disease. Trends Genet. 17:502-10
    • (2001) Trends Genet. , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 73
    • 0034785352 scopus 로고    scopus 로고
    • Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
    • Rioux JD, Daly MJ, Silverberg MS, Lindblad K, Steinhart H, et al. 2001. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat. Genet. 29:223-28
    • (2001) Nat. Genet. , vol.29 , pp. 223-228
    • Rioux, J.D.1    Daly, M.J.2    Silverberg, M.S.3    Lindblad, K.4    Steinhart, H.5
  • 74
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. 1996. The future of genetic studies of complex human diseases. Science 273:1516-17
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 75
    • 0028287094 scopus 로고
    • Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus
    • Ruiz J, Blanche H, Cohen N, Velho G, Cambien F, et al. 1994. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA 91:3662-65
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3662-3665
    • Ruiz, J.1    Blanche, H.2    Cohen, N.3    Velho, G.4    Cambien, F.5
  • 76
    • 0032813660 scopus 로고    scopus 로고
    • Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    • Rust S, Rosier M, Funke H, Real J, Amoura Z, et al. 1999. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat. Genet. 22:352-55
    • (1999) Nat. Genet. , vol.22 , pp. 352-355
    • Rust, S.1    Rosier, M.2    Funke, H.3    Real, J.4    Amoura, Z.5
  • 77
    • 0037456823 scopus 로고    scopus 로고
    • Genetics of gene expression surveyed in maize, mouse and man
    • Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, et al. 2003. Genetics of gene expression surveyed in maize, mouse and man. Nature 422:297-302
    • (2003) Nature , vol.422 , pp. 297-302
    • Schadt, E.E.1    Monks, S.A.2    Drake, T.A.3    Lusis, A.J.4    Che, N.5
  • 78
    • 0024417535 scopus 로고
    • Coronary risk associated with age and sex of parental heart disease in the Framingham Study
    • Schildkraut JM, Myers RH, Cupples LA, Kiely DK, Kannel WB. 1989. Coronary risk associated with age and sex of parental heart disease in the Framingham Study. Am. J. Cardiol 64:555-59
    • (1989) Am. J. Cardiol. , vol.64 , pp. 555-559
    • Schildkraut, J.M.1    Myers, R.H.2    Cupples, L.A.3    Kiely, D.K.4    Kannel, W.B.5
  • 79
    • 0037023783 scopus 로고    scopus 로고
    • Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice
    • Schreyer SA, Vick CM, LeBoeuf RC. 2002. Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice. J. Biol. Chem. 277:12364-68
    • (2002) J. Biol. Chem. , vol.277 , pp. 12364-12368
    • Schreyer, S.A.1    Vick, C.M.2    LeBoeuf, R.C.3
  • 80
    • 0031969967 scopus 로고    scopus 로고
    • Proliferation and the monoclonal origins of atherosclerotic lesions
    • Schwartz SM, Murry CE. 1998. Proliferation and the monoclonal origins of atherosclerotic lesions. Annu. Rev. Med. 49:437-60
    • (1998) Annu. Rev. Med. , vol.49 , pp. 437-460
    • Schwartz, S.M.1    Murry, C.E.2
  • 81
    • 0034604223 scopus 로고    scopus 로고
    • Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice
    • Shi W, Haberland ME, Jien ML, Shin DM, Lusis AJ. 2000. Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice. Circulation 102:75-81
    • (2000) Circulation , vol.102 , pp. 75-81
    • Shi, W.1    Haberland, M.E.2    Jien, M.L.3    Shin, D.M.4    Lusis, A.J.5
  • 82
    • 0034717201 scopus 로고    scopus 로고
    • Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: Evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism
    • Shi W, Wang NJ, Shih DM, Sun VZ, Wang X, Lusis AJ. 2000. Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism. Circ. Res. 86:1078-84
    • (2000) Circ. Res. , vol.86 , pp. 1078-1084
    • Shi, W.1    Wang, N.J.2    Shih, D.M.3    Sun, V.Z.4    Wang, X.5    Lusis, A.J.6
  • 84
    • 5444258912 scopus 로고    scopus 로고
    • CHD and atherosclerosis: Human epidemiological studies and trangenic mouse models
    • ed. LG Costa, C Furlong. Boston: Kluwer
    • Shih DM, Reddy S, Lusis AJ. 2001. CHD and atherosclerosis: human epidemiological studies and trangenic mouse models. In Paraoxonase (PON1) in Health and Disease, ed. LG Costa, C Furlong. Boston: Kluwer
    • (2001) Paraoxonase (PON1) in Health and Disease
    • Shih, D.M.1    Reddy, S.2    Lusis, A.J.3
  • 85
    • 0034665943 scopus 로고    scopus 로고
    • Common polymorphism in the promoter of the CD14 monocyte receptor gene is associated with acute myocardial infarction in Japanese men
    • Shimada K, Watanabe Y, Mokuno H, Iwama Y, Daida H, Yamaguchi H. 2000. Common polymorphism in the promoter of the CD14 monocyte receptor gene is associated with acute myocardial infarction in Japanese men. Am. J. Cardiol. 86:682-84, A8
    • (2000) Am. J. Cardiol. , vol.86 , pp. 682-684
    • Shimada, K.1    Watanabe, Y.2    Mokuno, H.3    Iwama, Y.4    Daida, H.5    Yamaguchi, H.6
  • 86
    • 0036238516 scopus 로고    scopus 로고
    • Sources of variability in genetic association studies: Insights from the analysis of hepatic lipase (LIPC)
    • Shohet RV, Vega GL, Bersot TP, Mahley RW, Grundy SM, et al. 2002. Sources of variability in genetic association studies: insights from the analysis of hepatic lipase (LIPC). Hum. Mutat. 19:536-42
    • (2002) Hum. Mutat. , vol.19 , pp. 536-542
    • Shohet, R.V.1    Vega, G.L.2    Bersot, T.P.3    Mahley, R.W.4    Grundy, S.M.5
  • 87
    • 0021824223 scopus 로고
    • Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
    • Sing CF, Davignon J. 1985. Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am. J. Hum. Genet. 37:268-85
    • (1985) Am. J. Hum. Genet. , vol.37 , pp. 268-285
    • Sing, C.F.1    Davignon, J.2
  • 89
    • 0345536531 scopus 로고
    • The increased risk of death from ischaemic heart disease in first degree relatives of 121 men and 96 women with ischaemic heart disease
    • Slack J, Evans KA. 1966. The increased risk of death from ischaemic heart disease in first degree relatives of 121 men and 96 women with ischaemic heart disease. J. Med. Genet. 2:239-57
    • (1966) J. Med. Genet. , vol.2 , pp. 239-257
    • Slack, J.1    Evans, K.A.2
  • 90
    • 0036798007 scopus 로고    scopus 로고
    • The allelic structure of common disease
    • Smith DJ, Lusis AJ. 2002. The allelic structure of common disease. Hum. Mol. Genet. 11:2455-61
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2455-2461
    • Smith, D.J.1    Lusis, A.J.2
  • 91
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: Rounding out the big picture
    • Spiegelman BM, Flier JS. 1996. Adipogenesis and obesity: rounding out the big picture. Cell 87:377-89
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 92
    • 0031443817 scopus 로고    scopus 로고
    • The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk
    • Staessen JA, Wang JG, Ginocchio G, Petrov V, Saavedra AP, et al. 1997. The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk. J. Hypertens. 15:1579-92
    • (1997) J. Hypertens , vol.15 , pp. 1579-1592
    • Staessen, J.A.1    Wang, J.G.2    Ginocchio, G.3    Petrov, V.4    Saavedra, A.P.5
  • 93
    • 0037112882 scopus 로고    scopus 로고
    • Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides
    • Talmud PJ, Hawe E, Martin S, Olivier M, Miller GJ, et-al. 2002. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum. Mol. Genet. 11:3039-46
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 3039-3046
    • Talmud, P.J.1    Hawe, E.2    Martin, S.3    Olivier, M.4    Miller, G.J.5
  • 94
    • 0029160845 scopus 로고
    • The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers
    • Thomas AE, Green FR, Lamlum H, Humphries SE. 1995. The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers. J. Med. Genet. 32:585-89
    • (1995) J. Med. Genet. , vol.32 , pp. 585-589
    • Thomas, A.E.1    Green, F.R.2    Lamlum, H.3    Humphries, S.E.4
  • 95
    • 0035960593 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction
    • Topol EJ, McCarthy J, Gabriel S, Moliterno DJ, Rogers WJ, et al. 2001. Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 104:2641-44
    • (2001) Circulation , vol.104 , pp. 2641-2644
    • Topol, E.J.1    McCarthy, J.2    Gabriel, S.3    Moliterno, D.J.4    Rogers, W.J.5
  • 96
    • 0037153045 scopus 로고    scopus 로고
    • New players in the genetics of stroke
    • Tournier-Lasserve E. 2002. New players in the genetics of stroke. N. Engl. J. Med. 347:1711-12
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1711-1712
    • Tournier-Lasserve, E.1
  • 97
    • 0037162376 scopus 로고    scopus 로고
    • Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice
    • Tward A, Xia YR, Wang XP, Shi YS, Park C, et al. 2002. Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice. Circulation 106:484-90
    • (2002) Circulation , vol.106 , pp. 484-490
    • Tward, A.1    Xia, Y.R.2    Wang, X.P.3    Shi, Y.S.4    Park, C.5
  • 98
    • 0018383857 scopus 로고
    • Polymorphism of apolipoprotein E. III. Effect of a single polymorphic gene locus on plasma lipid levels in man
    • Utermann G, Pruin N, Steinmetz A. 1979. Polymorphism of apolipoprotein E. III. Effect of a single polymorphic gene locus on plasma lipid levels in man. Clin. Genet. 15:63-72
    • (1979) Clin. Genet. , vol.15 , pp. 63-72
    • Utermann, G.1    Pruin, N.2    Steinmetz, A.3
  • 99
    • 0033652271 scopus 로고    scopus 로고
    • Genomewide search for type 2 diabetes-susceptibility genes in French whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
    • Vionnet N, Hani El H, Dupont S, Gallina S, Francke S, et al. 2000. Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am. J. Hum. Genet. 67:1470-80
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1470-80
    • Vionnet, N.1    Hani, El.H.2    Dupont, S.3    Gallina, S.4    Francke, S.5
  • 100
    • 0042387813 scopus 로고    scopus 로고
    • Assessing the performance of the haplotype block model of linkage disequilibrium
    • Wall JD, Pritchard JK. 2003. Assessing the performance of the haplotype block model of linkage disequilibrium. Am. J. Hum. Genet. 73:502-15
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 502-515
    • Wall, J.D.1    Pritchard, J.K.2
  • 101
    • 0344827206 scopus 로고    scopus 로고
    • Mutation in MEF2A in an inherited disorder with features of coronary artery disease
    • Wang L, Fan C, Topol SE, Topol EJ, Wang Q. 2003. Mutation in MEF2A in an inherited disorder with features of coronary artery disease. Science 302:1578-81
    • (2003) Science , vol.302 , pp. 1578-1581
    • Wang, L.1    Fan, C.2    Topol, S.E.3    Topol, E.J.4    Wang, Q.5
  • 102
    • 10744233196 scopus 로고    scopus 로고
    • Premature myocardial infarction novel susceptibility locus on chromosome 1p34-36 identified by genome-wide linkage analysis
    • Wang Q, Rao S, Shen G-Q, Li L, Moliterno DJ, et al. 2004. Premature myocardial infarction novel susceptibility locus on chromosome 1p34-36 identified by genome-wide linkage analysis. Am. J. Hum. Genet. 74:262-71
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 262-271
    • Wang, Q.1    Rao, S.2    Shen, G.-Q.3    Li, L.4    Moliterno, D.J.5
  • 103
    • 0036738377 scopus 로고    scopus 로고
    • Quantitative trait loci and candidate genes regulating HDL cholesterol: A murine chromosome map
    • Wang X, Paigen B. 2002. Quantitative trait loci and candidate genes regulating HDL cholesterol: a murine chromosome map. Arterioscler. Thromb. Vasc. Biol. 22:1390-401
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1390-1401
    • Wang, X.1    Paigen, B.2
  • 104
    • 0027374221 scopus 로고
    • Evidence for linkage of the apolipoprotein A-II locus to plasma apolipoprotein A-II and free fatty acid levels in mice and humans
    • Warden CH, Daluiski A, Bu X, Purcell-Huynh DA, De Meester C, et al. 1993. Evidence for linkage of the apolipoprotein A-II locus to plasma apolipoprotein A-II and free fatty acid levels in mice and humans. Proc. Natl. Acad. Sci. USA 90:10886-90
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10886-10890
    • Warden, C.H.1    Daluiski, A.2    Bu, X.3    Purcell-Huynh, D.A.4    De Meester, C.5
  • 105
    • 0034893106 scopus 로고    scopus 로고
    • A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): Analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q
    • Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, et al. 2001. A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am. J. Hum. Genet. 69:553-69
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 553-569
    • Wiltshire, S.1    Hattersley, A.T.2    Hitman, G.A.3    Walker, M.4    Levy, J.C.5
  • 106
    • 0038052656 scopus 로고    scopus 로고
    • Haplotype block partition with limited resources and applications to human chromosome 21 haplotype data
    • Zhang K, Sun F, Waterman MS, Chen T. 2003. Haplotype block partition with limited resources and applications to human chromosome 21 haplotype data. Am. J. Hum. Genet. 73:63-73
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 63-73
    • Zhang, K.1    Sun, F.2    Waterman, M.S.3    Chen, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.