Genes, environment and Oji-Cree type 2 diabetes

Clinical Biochemistry

Volumn 36, Issue 3, 2003, Pages 163-170

  Hegele, Robert A ^a   Zinman, Bernard ^b   Hanley, Anthony J G ^b   Harris, Stewart B ^c   Barrett, P Hugh ^d   Cao, Henian ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Aboriginal people; Cardiovascular disease; HNF1A; Risk factors; Transcription factors; Type 2 diabetes

Indexed keywords

DNA; HEPATOCYTE NUCLEAR FACTOR 1A; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADOLESCENT DISEASE; AGE; ALLELE; ANALYTIC METHOD; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; EPIDEMIC; ETHNIC GROUP; GENE; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRAIT; HEREDITY; HNF1A GENE; HUMAN; IN VITRO STUDY; METABOLISM; MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PREDICTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; RISK FACTOR;

EID: 0242417154     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(03)00004-3     Document Type: Review

References (46)

1. Harris S.B., Gittelsohn J., Hanley A.J.G. The prevalence of NIDDM and associated risk factors in native Canadians. Diabetes Care. 20:1997;185-197.
2. Shah B.R., Hux J.E., Zinman B. Increasing rates of ischemic heart disease in the native population of Ontario, Canada. Arch Intern Med. 160:2000;1862-1866.
3. Kriska A., Hanley A.J.G., Harris S.B., Zinman B. Association of physical activity, physical fitness and plasma insulin and glucose concentrations in an isolated Native Canadian population experiencing rapid lifestyle change. Diabetes Care. 24:2001;1787-1792.
4. Hanley A.J.G., Harris S.B., Gittelsohn J., Wolever T.M.S., Saksvig B., Zinman B. Overweight among children and adolescents in a Native Canadian community prevalence and associated factors . Am J Clin Nutr. 71:2000;693-700.
5. Gittelsohn J., Wolever T.M.S., Harris S.B., Harris-Giraldo R., Hanley A.J.G., Zinman B. Specific patterns of food consumption and preparation are associated with diabetes and obesity in a Native Canadian Community. J Nutr. 128:1998;541-547.
6. Wolever T.M.S., Hamad S., Gittelsohn J. Low dietary fibre and high protein intakes associated with newly diagnosed diabetes in a remote aboriginal community. Am J Clin Nutr. 66:1997;1470-1474.
7. Hegele R.A., Sun F., Harris S.B., Anderson C., Hanley A.J., Zinman B. Genome-wide scanning for type 2 diabetes susceptibility in Canadian Oji-Cree, using 190 microsatellite markers. J Hum Genet. 44:1999;10-14.
8. Busch C.P., Hegele R.A. Genetic determinants of type 2 diabetes mellitus. Clin Genet. 60:2001;243-254.
9. Hegele R.A., Cao H., Harris S.B., Hanley A.J., Zinman B. The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree. J Clin Endocrinol Metab. 84:1999;1077-1082.
10. Hegele R.A., Cao H., Harris S.B., Hanley A.J., Zinman B. Hepatocyte nuclear factor-1 alpha G319S. A private mutation in Oji-Cree associated with type 2 diabetes. Diabetes Care. 22:1999;524.
11. Hegele R.A., Hanley A.J., Zinman B., Harris S.B., Anderson C.M. Youth-onset type 2 diabetes (Y2DM) associated with HNF1A S319 in aboriginal Canadians. Diabetes Care. 22:1999;2095-2096.
12. Hegele R.A., Cao H., Hanley A.J., Zinman B., Harris S.B., Anderson C.M. Clinical utility of HNF1A genotyping for diabetes in aboriginal Canadians. Diabetes Care. 23:2000;775-778.
13. Triggs-Raine B.L., Kirkpatrick R.D., Kelly S.L. HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community. Proc Natl Acad Sci USA. 99:2002;4614-4619.
14. Hegele R.A., Hanley A.J., Zinman B., Harris S.B., Anderson C.M. Disparity between association and linkage analysis for HNF1A G319S in type 2 diabetes in Canadian Oji-Cree. J Hum Genet. 45:2000;184-187.
15. Hegele R.A., Cao H., Harris S.B., Zinman B., Hanley A.J., Anderson C.M. Gender, obesity, hepatic nuclear factor-1alpha G319S, and the age-of-onset of type 2 diabetes in Canadian Oji-Cree. Int J Obes Relat Metab Disord. 24:2000;1062-1064.
16. Hegele R.A., Harris S.B., Zinman B. Hemochromatosis and diabetes mellitus. Ann Intern Med. 129:1998;587.
17. Hegele R.A., Harris S.B., Zinman B., Hanley A.J., Cao H. Absence of association of type 2 diabetes with CAPN10 and PC-1 polymorphisms in Oji-Cree. Diabetes Care. 24:2001;1498-1499.
18. Hegele R.A., Cao H., Harris S.B., Zinman B., Hanley A.J., Anderson C.M. Peroxisome proliferator-activated receptor-gamma2 P12A and type 2 diabetes in Canadian Oji-Cree. J Clin Endocrinol Metab. 85:2000;2014-2019.
19. Mok A., Cao H., Zinman B. A single nucleotide polymorphism in protein tyrosine phosphatase PTP-1B is associated with protection from diabetes or impaired glucose tolerance in Oji-Cree. J Clin Endocrinol Metab. 87:2002;724-727.
20. Hegele R.A., Connelly P.W., Scherer S.W. Paraoxonase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 82:1997;3373-3377.
21. Hegele R.A., Connelly P.W., Scherer S.W. Paraoxonase-2 G148 variant in an aboriginal Canadian girl with non-insulin-dependent diabetes. Lancet. 350:1997;785.
22. Hegele R.A., Kwan K., Harris S.B., Hanley A.J., Zinman B., Cao H. NAT2 polymorphism associated with plasma glucose concentration in Canadian Oji-Cree. Pharmacogenetics. 10:2000;233-238.
23. Hegele R.A., Harris S.B., Zinman B. Variation in the AU(AT)-rich element within the 3′-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians. J Clin Endocrinol Metab. 83:1998;3980-3983.
24. Hegele R.A., Cao H., Harris S.B., Hanley A.J., Zinman B., Connelly P.W. The private hepatocyte nuclear factor-1alpha G319S variant is associated with plasma lipoprotein variation in Canadian Oji-Cree. Arterioscler Thromb Vasc Biol. 20:2000;217-222.
25. Hegele R.A., Connelly P.W., Hanley A.J., Sun F., Harris S.B., Zinman B. Common genomic variation in the APOC3 promoter associated with variation in plasma lipoproteins. Arterioscler Thromb Vasc Biol. 17:1997;2753-2758.
26. Hegele R.A., Connelly P.W., Hanley A.J., Sun F., Harris S.B., Zinman B. Common genomic variants associated with variation in plasma lipoproteins in young aboriginal Canadians. Arterioscler Thromb Vasc Biol. 17:1997;1060-1066.
27. Hegele R.A., Harris S.B., Connelly P.W. Genetic variation in paraoxonase-2 is associated with variation in plasma lipoproteins in Canadian Oji-Cree. Clin Genet. 54:1998;394-399.
28. Hegele R.A., Zinman B., Hanley A.J., Harris S., Connelly P.W. A common mtDNA polymorphism associated with variation in plasma triglyceride concentration. Am J Hum Genet. 60:1997;1552-1555.
29. Fanella S., Harris S.B., Young T.K. Association between PON1 L/M55 polymorphism and plasma lipoproteins in two Canadian aboriginal populations. Clin Chem Lab Med. 38:2000;413-420.
30. Hegele R.A., Harris S.B., Brunt J.H. Absence of association between genetic variation in the LIPC gene promoter and plasma lipoproteins in three Canadian populations. Atherosclerosis. 146:1999;153-160.
31. Hegele R.A., Wang J., Harris S.B. Variable association between genetic variation in the CYP7 gene promoter and plasma lipoproteins in three Canadian populations. Atherosclerosis. 154:2001;579-587.
32. Hegele R.A., Harris S.B., Hanley A.J., Sun F., Connelly P.W., Zinman B. Angiotensinogen gene variation associated with variation in blood pressure in aboriginal Canadians. Hypertension. 29:1997;1073-1077.
33. Hegele R.A., Harris S.B., Hanley A.J., Cao H., Zinman B. G protein beta3 subunit gene variant, and blood pressure variation in Canadian Oji-Cree. Hypertension. 32:1998;688-992.
34. Hegele R.A., Harris S.B., Hanley A.J., Zinman B. Association between AGT codon 235 polymorphism and variation in serum concentrations of creatinine and urea in Canadian Oji-Cree. Clin Genet. 55:1999;438-443.
35. Hegele R.A., Harris S.B., Hanley A.J., Zinman B. Association between AGT T235 variant and microalbuminuria in Canadian Oji-Cree with type 2 diabetes mellitus. Clin Biochem. 32:1999;201-205.
36. Hegele R.A., Harris S.B., Zinman B., Hanley A.J., Connelly P.W. Increased plasma apolipoprotein B-containing lipoproteins associated with increased urinary albumin within the microalbuminuria range in type 2 diabetes. Clin Biochem. 32:1999;143-148.
37. Hegele R.A., Harris S.B., Hanley A.J., Sun F., Connelly P.W., Zinman B. -6A promoter variant of angiotensinogen, and blood pressure variation in Canadian Oji-Cree. J Hum Genet. 43:1998;37-41.
38. Busch C.P., Harris S.B., Hanley A.J., Zinman B., Hegele R.A. The ADD1 G460W polymorphism is not associated with variation in blood pressure in Canadian Oji-Cree. J Hum Genet. 44:1999;225-229.
39. Hegele R.A., Harris S.B., Hanley A.J., Sadikian S., Connelly P.W., Zinman B. Genetic variation of intestinal fatty acid-binding protein associated with variation in body mass in aboriginal Canadians. J Clin Endocrinol Metab. 81:1996;4334-4337.
40. Hegele R.A., Cao H., Harris S.B., Zinman B., Hanley A.J., Anderson C.M. Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians. Physiol Genomics. 3:2000;39-44.
41. Hegele R.A., Harris S.B., Hanley A.J., Azouz H., Connelly P.W., Zinman B. Absence of association between genetic variation of the beta 3-adrenergic receptor and metabolic phenotypes in Oji-Cree. Diabetes Care. 21:1998;851-854.
42. Hegele R.A., Wolever T.M., Hanley A.J., Harris S.B., Zinman B. Methylene tetrahydrofolate reductase gene, dietary folate, NIDDM, and atherosclerosis in Canadian Oji-Cree. Diabetes Care. 21:1998;322-323.
43. Hegele R.A., Harris S.B., Cao H., Hanley A.J., Zinman B. Factor V Leiden (F5 Q506), and vascular disease in Canadian Oji-Cree. Diabetes Care. 21:1998;1203.
44. Hegele R.A. Genetic prediction of atherosclerosis lessons from studies in native Canadian populations . Clin Chim Acta. 286:1999;47-61.
45. Sellers E.A., Triggs-Raine B., Rockman-Greenberg C., Dean H.J. The prevalence of the HNF-1alpha G319S mutation in Canadian aboriginal youth with type 2 diabetes. Diabetes Care. 25:2002;2202-2206.
46. Stride A., Shepherd M., Frayling T.M., Bulman M.P., Ellard S., Hattersley A.T. Intrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in HNF-1alpha gene mutation carriers. Diabetes Care. 25:2002;2287-2291.