JAK2 and MPL mutations in myeloproliferative neoplasms: Discovery and science

Leukemia

Volumn 22, Issue 10, 2008, Pages 1813-1817

  Kilpivaara, O ^a   Levine, R L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE 2; JANUS KINASE 2 INHIBITOR; JANUS KINASE INHIBITOR; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANEMIA; CANCER GENETICS; CANCER GROWTH; CANCER RISK; CARCINOGENESIS; CELL PROLIFERATION; CHROMOSOME ABERRATION; CLINICAL TRIAL; DISEASE COURSE; DISEASE SEVERITY; DNA SEQUENCE; DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETIC VARIABILITY; GENOME ANALYSIS; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL; HETEROZYGOSITY LOSS; HOMOZYGOSITY; HUMAN; LEUKOCYTOSIS; MALIGNANT TRANSFORMATION; MUTATIONAL ANALYSIS; MYELOID METAPLASIA; MYELOPROLIFERATIVE DISORDER; NONHUMAN; ONCOGENE; PATHOPHYSIOLOGY; PHENOTYPE; PLEIOTROPY; POLYCYTHEMIA VERA; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; THROMBOCYTOSIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; UNIPARENTAL DISOMY;

EID: 54149085320     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.229     Document Type: Review

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