Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide

British Journal of Pharmacology

Volumn 155, Issue 4, 2008, Pages 535-546

  Rodriguez Rodriguez, R ^a,b   Stankevicius, E ^a   Herrera, M D ^c   Ostergaard L ^a   Andersen, M R ^d   Ruiz Gutierrez, V ^b   Simonsen, U ^a,d  

^a AARHUS UNIVERSITY   (Denmark)

^b INSTITUTO DE LA GRASA   (Spain)

^c UNIVERSITY OF SEVILLE   (Spain)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

ACh; Calcium; Endothelium; Nitric oxide; NO microsensor; Oleanolic acid

Indexed keywords

ACETYLCHOLINE; CALCIUM ION; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDOMETACIN; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; NORADRENALIN; OLEANOLIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; MEDITERRANEAN DIET; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION; SUPERIOR MESENTERIC ARTERY; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMANS; MALE; MESENTERIC ARTERIES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OLEANOLIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLANT OILS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; UMBILICAL VEINS;

EID: 53849116438     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.289     Document Type: Article

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