메뉴 건너뛰기




Volumn 107, Issue 3, 2008, Pages 814-822

Mitogen-activated protein kinase activity may not be necessary for the neuropathology of Niemann-Pick type C mice

Author keywords

Axonal spheroids; Extracellular signal regulated kinase 1; Extracellular signal regulated kinase 2; Oligodendrocytes; Tau phosphorylation; Tauopathy

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TAU PROTEIN;

EID: 53749100314     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05657.x     Document Type: Article
Times cited : (7)

References (46)
  • 1
    • 0030916610 scopus 로고    scopus 로고
    • Ultrastructural characterization of the tau-immunoreactive tubules in the oligodendroglial perikarya and their inner loop processes in progressive supranuclear palsy
    • Arima K., Nakamura M., Sunohara N., Ogawa M., Anno M., Izumiyama Y., Hirai S. Ikeda K. (1997) Ultrastructural characterization of the tau-immunoreactive tubules in the oligodendroglial perikarya and their inner loop processes in progressive supranuclear palsy. Acta Neuropathol. (Berl) 93, 558 566.
    • (1997) Acta Neuropathol. (Berl) , vol.93 , pp. 558-566
    • Arima, K.1    Nakamura, M.2    Sunohara, N.3    Ogawa, M.4    Anno, M.5    Izumiyama, Y.6    Hirai, S.7    Ikeda, K.8
  • 2
    • 0038123159 scopus 로고    scopus 로고
    • Synthesis and MEK1 inhibitory activities of imido-substituted 2-chloro-1,4-naphthoquinones
    • Bakare O., Ashendel C. L., Peng H., Zalkow L. H. Burgess E. M. (2003) Synthesis and MEK1 inhibitory activities of imido-substituted 2-chloro-1,4-naphthoquinones. Bioorg. Med. Chem. 11, 3165 3170.
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 3165-3170
    • Bakare, O.1    Ashendel, C.L.2    Peng, H.3    Zalkow, L.H.4    Burgess, E.M.5
  • 3
    • 26444490106 scopus 로고    scopus 로고
    • Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain
    • Bi X., Liu J., Yao Y., Baudry M. Lynch G. (2005) Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain. Am. J. Pathol. 167, 1081 1092.
    • (2005) Am. J. Pathol. , vol.167 , pp. 1081-1092
    • Bi, X.1    Liu, J.2    Yao, Y.3    Baudry, M.4    Lynch, G.5
  • 4
    • 21844475890 scopus 로고    scopus 로고
    • Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: Role of microtubule-associated protein 2 as an effector
    • Bjorkblom B., Ostman N., Hongisto V., Komarovski V., Filen J. J., Nyman T. A., Kallunki T., Courtney M. J. Coffey E. T. (2005) Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector. J. Neurosci. 25, 6350 6361.
    • (2005) J. Neurosci. , vol.25 , pp. 6350-6361
    • Bjorkblom, B.1    Ostman, N.2    Hongisto, V.3    Komarovski, V.4    Filen, J.J.5    Nyman, T.A.6    Kallunki, T.7    Courtney, M.J.8    Coffey, E.T.9
  • 5
    • 0036703779 scopus 로고    scopus 로고
    • Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model
    • Bu B., Li J., Davies P. Vincent I. (2002a) Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model. J. Neurosci. 22, 6515 6525.
    • (2002) J. Neurosci. , vol.22 , pp. 6515-6525
    • Bu, B.1    Li, J.2    Davies, P.3    Vincent, I.4
  • 6
    • 0036968946 scopus 로고    scopus 로고
    • Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles
    • Bu B., Klunemann H., Suzuki K., Li J., Bird T., Jin L. W. Vincent I. (2002b) Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles. Neurobiol. Dis. 11, 285 297.
    • (2002) Neurobiol. Dis. , vol.11 , pp. 285-297
    • Bu, B.1    Klunemann, H.2    Suzuki, K.3    Li, J.4    Bird, T.5    Jin, L.W.6    Vincent, I.7
  • 7
    • 0035145475 scopus 로고    scopus 로고
    • Cyclic AMP and mitogen-activated protein kinases are required for glutamate-dependent cyclic AMP response element binding protein and Elk-1 phosphorylation in the dorsal striatum in vivo
    • Choe E. S. McGinty J. F. (2001) Cyclic AMP and mitogen-activated protein kinases are required for glutamate-dependent cyclic AMP response element binding protein and Elk-1 phosphorylation in the dorsal striatum in vivo. J. Neurochem. 76, 401 412.
    • (2001) J. Neurochem. , vol.76 , pp. 401-412
    • Choe, E.S.1    McGinty, J.F.2
  • 8
    • 21644480795 scopus 로고    scopus 로고
    • Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis
    • Dangi S. Shapiro P. (2005) Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis. J. Biol. Chem. 280, 24524 24531.
    • (2005) J. Biol. Chem. , vol.280 , pp. 24524-24531
    • Dangi, S.1    Shapiro, P.2
  • 9
    • 0031028163 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases by purine analogues: Crystal structure of human cdk2 complexed with roscovitine
    • De Azevedo W. F., Leclerc S., Meijer L., Havlicek L., Strnad M. Kim S. H. (1997) Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur. J. Biochem. 243, 518 526.
    • (1997) Eur. J. Biochem. , vol.243 , pp. 518-526
    • De Azevedo, W.F.1    Leclerc, S.2    Meijer, L.3    Havlicek, L.4    Strnad, M.5    Kim, S.H.6
  • 10
    • 0019399653 scopus 로고
    • Neuropathology of various types of Niemann-Pick disease
    • Elleder M. Jirasek A. (1981) Neuropathology of various types of Niemann-Pick disease. Acta Neuropathol. Suppl. 7, 201 203.
    • (1981) Acta Neuropathol. Suppl. , vol.7 , pp. 201-203
    • Elleder, M.1    Jirasek, A.2
  • 11
    • 0021830120 scopus 로고
    • Niemann-Pick disease type C. Study on the nature of the cerebral storage process
    • Elleder M., Jirasek A., Smid F., Ledvinova J. Besley G. T. (1985) Niemann-Pick disease type C. Study on the nature of the cerebral storage process. Acta Neuropathol. 66, 325 336.
    • (1985) Acta Neuropathol. , vol.66 , pp. 325-336
    • Elleder, M.1    Jirasek, A.2    Smid, F.3    Ledvinova, J.4    Besley, G.T.5
  • 12
    • 0035659377 scopus 로고    scopus 로고
    • Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies
    • Ferrer I., Blanco R., Carmona M. Puig B. (2001) Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies. J. Neural. Transm. 108, 1397 1415.
    • (2001) J. Neural. Transm. , vol.108 , pp. 1397-1415
    • Ferrer, I.1    Blanco, R.2    Carmona, M.3    Puig, B.4
  • 14
    • 0037246583 scopus 로고    scopus 로고
    • Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic grain disease
    • Ferrer I., Barrachina M., Tolnay M., Rey M. J., Vidal N., Carmona M., Blanco R. Puig B. (2003b) Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic grain disease. Brain Pathol. 13, 62 78.
    • (2003) Brain Pathol. , vol.13 , pp. 62-78
    • Ferrer, I.1    Barrachina, M.2    Tolnay, M.3    Rey, M.J.4    Vidal, N.5    Carmona, M.6    Blanco, R.7    Puig, B.8
  • 15
    • 0035934173 scopus 로고    scopus 로고
    • Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor
    • German D. C., Quintero E. M., Liang C., Xie C. Dietschy J. M. (2001) Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor. Neuroscience 105, 999 1005.
    • (2001) Neuroscience , vol.105 , pp. 999-1005
    • German, D.C.1    Quintero, E.M.2    Liang, C.3    Xie, C.4    Dietschy, J.M.5
  • 16
    • 0032191105 scopus 로고    scopus 로고
    • Filamentous nerve cell inclusions in neurodegenerative diseases
    • Goedert M., Spillantini M. G. Davies S. W. (1998) Filamentous nerve cell inclusions in neurodegenerative diseases. Curr. Opin. Neurobiol. 8, 619 632.
    • (1998) Curr. Opin. Neurobiol. , vol.8 , pp. 619-632
    • Goedert, M.1    Spillantini, M.G.2    Davies, S.W.3
  • 17
    • 14644394938 scopus 로고    scopus 로고
    • The MAP kinase pathway is upstream of the activation of GSK3beta that enables it to phosphorylate MAP1B and contributes to the stimulation of axon growth
    • Goold R. G. Gordon-Weeks P. R. (2005) The MAP kinase pathway is upstream of the activation of GSK3beta that enables it to phosphorylate MAP1B and contributes to the stimulation of axon growth. Mol. Cell. Neurosci. 28, 524 534.
    • (2005) Mol. Cell. Neurosci. , vol.28 , pp. 524-534
    • Goold, R.G.1    Gordon-Weeks, P.R.2
  • 19
    • 0344011447 scopus 로고    scopus 로고
    • Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice
    • Hallows J. L., Chen K., DePinho R. A. Vincent I. (2003) Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice. J. Neurosci. 23, 10633 10644.
    • (2003) J. Neurosci. , vol.23 , pp. 10633-10644
    • Hallows, J.L.1    Chen, K.2    Depinho, R.A.3    Vincent, I.4
  • 21
    • 26844433190 scopus 로고    scopus 로고
    • Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies
    • Higuchi M., Zhang B., Forman M. S., Yoshiyama Y., Trojanowski J. Q. Lee V. M. (2005) Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies. J. Neurosci. 25, 9434 9443.
    • (2005) J. Neurosci. , vol.25 , pp. 9434-9443
    • Higuchi, M.1    Zhang, B.2    Forman, M.S.3    Yoshiyama, Y.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 22
    • 33645100089 scopus 로고    scopus 로고
    • Relationship between neuronal loss and tangle formation in neurons and oligodendroglia in progressive supranuclear palsy
    • Jin C., Katayama S., Hiji M., Watanabe C., Noda K., Nakamura S. Matsumoto M. (2006) Relationship between neuronal loss and tangle formation in neurons and oligodendroglia in progressive supranuclear palsy. Neuropathology 26, 50 56.
    • (2006) Neuropathology , vol.26 , pp. 50-56
    • Jin, C.1    Katayama, S.2    Hiji, M.3    Watanabe, C.4    Noda, K.5    Nakamura, S.6    Matsumoto, M.7
  • 23
    • 32544454004 scopus 로고    scopus 로고
    • The relationship between histopathological features of progressive supranuclear palsy and disease duration
    • Josephs K. A., Mandrekar J. N. Dickson D. W. (2006) The relationship between histopathological features of progressive supranuclear palsy and disease duration. Parkinsonism Relat. Disord. 12, 109 112.
    • (2006) Parkinsonism Relat. Disord. , vol.12 , pp. 109-112
    • Josephs, K.A.1    Mandrekar, J.N.2    Dickson, D.W.3
  • 24
  • 25
    • 0030768084 scopus 로고    scopus 로고
    • Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene
    • Loftus S. K., Morris J. A., Carstea E. D. et al. (1997) Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science 277, 232 235.
    • (1997) Science , vol.277 , pp. 232-235
    • Loftus, S.K.1    Morris, J.A.2    Carstea, E.D.3
  • 28
    • 0034281386 scopus 로고    scopus 로고
    • Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase
    • Namgung U. Xia Z. (2000) Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. J. Neurosci. 20, 6442 6451.
    • (2000) J. Neurosci. , vol.20 , pp. 6442-6451
    • Namgung, U.1    Xia, Z.2
  • 29
    • 0029367097 scopus 로고
    • Neurofilament phosphorylation
    • Pant H. C. Veeranna (1995) Neurofilament phosphorylation. Biochem. Cell Biol. 73, 575 592.
    • (1995) Biochem. Cell Biol. , vol.73 , pp. 575-592
    • Pant, H.C.1    Veeranna2
  • 30
    • 0027421625 scopus 로고
    • Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments
    • Paudel H. K., Lew J., Ali Z. Wang J. H. (1993) Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments. J. Biol. Chem. 268, 23512 23518.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23512-23518
    • Paudel, H.K.1    Lew, J.2    Ali, Z.3    Wang, J.H.4
  • 31
    • 0026733002 scopus 로고
    • PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
    • Qui M. S. Green S. H. (1992) PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity. Neuron 9, 705 717.
    • (1992) Neuron , vol.9 , pp. 705-717
    • Qui, M.S.1    Green, S.H.2
  • 32
    • 4744372663 scopus 로고    scopus 로고
    • Tau-inclusion body formation in oligodendroglia: The role of stress proteins and proteasome inhibition
    • Richter-Landsberg C. Bauer N. G. (2004) Tau-inclusion body formation in oligodendroglia: the role of stress proteins and proteasome inhibition. Int. J. Dev. Neurosci. 22, 443 451.
    • (2004) Int. J. Dev. Neurosci. , vol.22 , pp. 443-451
    • Richter-Landsberg, C.1    Bauer, N.G.2
  • 33
    • 53749089698 scopus 로고    scopus 로고
    • Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice
    • Sawamura N., Gong J. S., Garver W. S., Heidenreich R. A., Ninomiya H., Ohno K., Yanagisawa K. Michikawa M. (2001) Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice. J. Biol. Chem. 4, 4.
    • (2001) J. Biol. Chem. , vol.4 , pp. 4
    • Sawamura, N.1    Gong, J.S.2    Garver, W.S.3    Heidenreich, R.A.4    Ninomiya, H.5    Ohno, K.6    Yanagisawa, K.7    Michikawa, M.8
  • 34
    • 0037340949 scopus 로고    scopus 로고
    • Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells
    • Sawamura N., Gong J. S., Chang T. Y., Yanagisawa K. Michikawa M. (2003) Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells. J. Neurochem. 84, 1086 1096.
    • (2003) J. Neurochem. , vol.84 , pp. 1086-1096
    • Sawamura, N.1    Gong, J.S.2    Chang, T.Y.3    Yanagisawa, K.4    Michikawa, M.5
  • 37
    • 0036135106 scopus 로고    scopus 로고
    • Morphological and biochemical correlations of abnormal tau filaments in progressive supranuclear palsy
    • Takahashi M., Weidenheim K. M., Dickson D. W. Ksiezak-Reding H. (2002) Morphological and biochemical correlations of abnormal tau filaments in progressive supranuclear palsy. J. Neuropathol. Exp. Neurol. 61, 33 45.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 33-45
    • Takahashi, M.1    Weidenheim, K.M.2    Dickson, D.W.3    Ksiezak-Reding, H.4
  • 38
    • 2942624018 scopus 로고    scopus 로고
    • Perturbed myelination process of premyelinating oligodendrocyte in Niemann-Pick type C mouse
    • Takikita S., Fukuda T., Mohri I., Yagi T. Suzuki K. (2004) Perturbed myelination process of premyelinating oligodendrocyte in Niemann-Pick type C mouse. J. Neuropathol. Exp. Neurol. 63, 660 673.
    • (2004) J. Neuropathol. Exp. Neurol. , vol.63 , pp. 660-673
    • Takikita, S.1    Fukuda, T.2    Mohri, I.3    Yagi, T.4    Suzuki, K.5
  • 39
    • 0031006939 scopus 로고    scopus 로고
    • Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
    • Vincent I., Jicha G., Rosado M. Dickson D. W. (1997) Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J. Neurosci. 17, 3588 3598.
    • (1997) J. Neurosci. , vol.17 , pp. 3588-3598
    • Vincent, I.1    Jicha, G.2    Rosado, M.3    Dickson, D.W.4
  • 40
    • 0031685160 scopus 로고    scopus 로고
    • Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
    • Vincent I., Zheng J. H., Dickson D. W., Kress Y. Davies P. (1998) Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease. Neurobiol. Aging 19, 287 296.
    • (1998) Neurobiol. Aging , vol.19 , pp. 287-296
    • Vincent, I.1    Zheng, J.H.2    Dickson, D.W.3    Kress, Y.4    Davies, P.5
  • 41
    • 0037396865 scopus 로고    scopus 로고
    • Understanding Niemann-Pick type C disease: A fat problem
    • Vincent I., Bu B. Erickson R. P. (2003a) Understanding Niemann-Pick type C disease: a fat problem. Curr. Opin. Neurol. 16, 155 161.
    • (2003) Curr. Opin. Neurol. , vol.16 , pp. 155-161
    • Vincent, I.1    Bu, B.2    Erickson, R.P.3
  • 42
    • 0642286567 scopus 로고    scopus 로고
    • The cell cycle and human neurodegenerative disease
    • Vincent I., Pae C. I. Hallows J. L. (2003b) The cell cycle and human neurodegenerative disease. Prog. Cell Cycle Res. 5, 31 34.
    • (2003) Prog. Cell Cycle Res. , vol.5 , pp. 31-34
    • Vincent, I.1    Pae, C.I.2    Hallows, J.L.3
  • 43
    • 0037089805 scopus 로고    scopus 로고
    • Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease
    • Voikar V., Rauvala H. Ikonen E. (2002) Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease. Behav. Brain Res. 132, 1 10.
    • (2002) Behav. Brain Res. , vol.132 , pp. 1-10
    • Voikar, V.1    Rauvala, H.2    Ikonen, E.3
  • 44
    • 23644445386 scopus 로고    scopus 로고
    • MEKK1 controls neurite regrowth after experimental injury by balancing ERK1/2 and JNK2 signaling
    • Waetzig V. Herdegen T. (2005) MEKK1 controls neurite regrowth after experimental injury by balancing ERK1/2 and JNK2 signaling. Mol. Cell. Neurosci. 30, 67 78.
    • (2005) Mol. Cell. Neurosci. , vol.30 , pp. 67-78
    • Waetzig, V.1    Herdegen, T.2
  • 45
    • 4344637728 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice
    • Zhang M., Li J., Chakrabarty P., Bu B. Vincent I. (2004) Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice. Am. J. Pathol. 165, 843 853.
    • (2004) Am. J. Pathol. , vol.165 , pp. 843-853
    • Zhang, M.1    Li, J.2    Chakrabarty, P.3    Bu, B.4    Vincent, I.5
  • 46
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu X., Raina A. K., Rottkamp C. A., Aliev G., Perry G., Boux H. Smith M. A. (2001) Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76, 435 441.
    • (2001) J. Neurochem. , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.