In vitro biological evaluation of novel 7-O-dialkylaminoalkyl cytotoxic pectolinarigenin derivatives against a panel of human cancer cell lines

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 20, 2008, Pages 5431-5434

  Bonesi, Marco ^a   Tundis, Rosa ^a   Deguin, Brigitte ^b   Loizzo, Monica R ^a   Menichini, Federica ^c   Tillequin, François ^b   Menichini, Francesco ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cytotoxic activity; Dialkylaminoalkyl side chain; Pectolinarigenin

Indexed keywords

ALIPHATIC AMINE; CYTOTOXIC AGENT; DIMETHYLAMINE; LINARIA REFLEXA EXTRACT; PECTOLINARIGENIN DERIVATIVE; PECTOLINARIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

AMELANOTIC MELANOMA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; IN VITRO STUDY; KIDNEY CARCINOMA; LINARIA; LINARIA REFLEXA; LIVER CELL CARCINOMA; LUNG CARCINOMA; MELANOMA; SKIN FIBROBLAST; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CACO-2 CELLS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; CHROMONES; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONES; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; RHODAMINES;

LINARIA;

EID: 53449089890     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.037     Document Type: Article

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