Tumor necrosis factor-α downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-α 1

Circulation Research

Volumn 103, Issue 6, 2008, Pages 591-597

  Yan, Guijun ^a   You, Bei ^a   Chen, Shao Ping ^a   Liao, James K ^b   Sun, Jianxin ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

ENOS; MRNA; Stability; TNF ; Translation elongation factor 1

Indexed keywords

BINDING PROTEIN; ELONGATION FACTOR 1ALPHA; ELONGATION FACTOR 1ALPHA 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; LUCIFERASE; MESSENGER RNA; RIBONUCLEOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; EEF1A1 PROTEIN, HUMAN; ELONGATION FACTOR 1;

3' UNTRANSLATED REGION; ADENOVIRUS; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; AORTA; ARTICLE; ATTENUATION; CROSS LINKING; CYTOSOLIC FRACTION; DOWN REGULATION; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE FUSION; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA GEL BLOT ANALYSIS; RNA STABILITY; UMBILICAL VEIN; WESTERN BLOTTING; ANIMAL; CATTLE; CELL CULTURE; CELL STRAIN COS1; CERCOPITHECUS; COMPARATIVE STUDY; DRUG ANTAGONISM; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DOWN-REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; NITRIC OXIDE SYNTHASE TYPE III; PEPTIDE ELONGATION FACTOR 1; PROTEIN BIOSYNTHESIS; RNA STABILITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 53249149631     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.173963     Document Type: Article

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