Molecular characteristics of serrated adenomas of the colorectum

Gut

Volumn 51, Issue 2, 2002, Pages 200-206

  Sawyer, E J ^a   Cerar, A ^b   Hanby, A M ^c   Gorman, P ^a   Arends, M ^d   Talbot, I C ^e   Tomlinson, I P M ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b INSTITUTE OF PATHOLOGY   (Slovenia)

^c ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ST MARK S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APC; BETA CATENIN; PROTEIN P53; UVOMORULIN; WNT PROTEIN;

ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CLINICAL PATHWAY; COLON ADENOMA; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOARCHITECTURE; DNA HYBRIDIZATION; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; GENETIC STABILITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; ONCOGENE K RAS; PRIORITY JOURNAL; RECTUM ADENOMA;

ADENOMA; BETA CATENIN; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; GENE EXPRESSION PROFILING; GENES, APC; GENES, P53; GENES, RAS; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MUTATION; TRANS-ACTIVATORS;

EID: 0036070842     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.51.2.200     Document Type: Article

References (28)

1. Mixed hyperplastic adenomatous polyps/serrated adenomas. A distinct form of colorectal neoplasia
2. Small colorectal serrated adenomas: Endoscopic findings
3. Infrequent K-ras codon 12 mutation in serrated adenomas of human colorectum
4. Genetic alterations of mixed hyperplastic adenomatous polyps in the colon and rectum
5. Frequent p53 gene mutations in serrated adenomas of the colorectum
6. Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
7. DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutator pathway for colorectal cancer?
8. Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)
9. 'Serrated' adenoma of the colorectum, with reference to its gastric differentiation and its malignant potential
10. Serrated adenoma: A clinicopathological, DNA ploidy, and immunohistochemical study
11. Phenotypic and molecular characteristics of hyperplastic polyposis
12. Hyperplastic polyps
13. Polyps and cancer of the large bowel: A necropsy study in Liverpool
14. Serrated adenomatous polyposis in humans
15. Serrated adenoma and colorectal cancer
16. Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
17. Inherited susceptibility to colorectal adenomas and carcinomas: Evidence for a new predisposition gene on 15q 14-q22
18. p53 gene mutations in oropharyngeal carcinomas: A comparison of solitary and multiple primary tumours and lymph-node metastases
19. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
20. Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum
21. Colorectal carcinoma associated with serrated adenoma - Prevalence, histological features and prognosis
22. Biological significance of MSI-L status in colorectal tumours
23. Nuclear translocation of beta-catenin in colorectal cancer
24. Familial polyposis: Recent advances
25. Infrequent APC mutations in serrated adenoma
26. Ki-ras mutations in adenomas: A characteristic of cancer-bearing colorectal mucosa
27. DNA flow cytometry, p53 levels and proliferative cell nuclear antigen in human colon dysplastic, precancerous and cancerous tissues
28. Clinicopathological features of serrated adenoma of the colorectum: Comparison with traditional adenoma