Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 14, 2004, Pages 4821-4826

  Sodhi, Akrit ^a,b   Montaner, Silvia ^a   Patel, Vyomesh ^a   Gómez Román, José Javier ^c   Li, Yi ^d   Sausville, Edward A ^e   Sawait, Earl T ^b   Gutkind, J Silvio ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

7 hydroxystaurosporine; Human herpesvirus 8; Kaposi's sarcoma associated herpesvirus

Indexed keywords

7 HYDROXYSTAUROSPORINE; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; VASCULOTROPIN;

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE TRANSFER; GENOTYPE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROVIRUS; SARCOMA; TUMOR; WESTERN BLOTTING;

ANIMALS; CELL LINE, TRANSFORMED; GTP-BINDING PROTEINS; HERPESVIRUS 8, HUMAN; MICE; MICE, NUDE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; SARCOMA, KAPOSI; STAUROSPORINE;

ANIMALIA; DNA VIRUSES; HERPESVIRIDAE; HUMAN HERPESVIRUS 8; UNIDENTIFIED RETROVIRUS;

EID: 1842687489     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0400835101     Document Type: Article

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