Effect of Rp and Sp phosphorothioate substitution at the scissile site on the cleavage activity of deoxyribozyme 10-23

Current Organic Chemistry

Volumn 12, Issue 12, 2008, Pages 1004-1009

  Nawrot, Barbara ^a   Widera, Kinga ^a   Sobczak, Milena ^a   Wojcik, Marzena ^a   Stec, Wojciech J ^a  

^a CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Catalysis reaction; Chimeric oligonucleotide; Cleavage Activity; Deoxyribozyme 10 23; Phosphorothioate; Scissile Site

Indexed keywords

COORDINATION REACTIONS; DNA; METAL IONS; OLIGONUCLEOTIDES; REACTION KINETICS;

CATALYSE REACTION; CHIMERIC OLIGONUCLEOTIDE; CLEAVAGE ACTIVITIES; CLEAVAGE REACTION; DEOXYRIBOZYME 10-23; DEOXYRIBOZYMES; METAL ION CONCENTRATION; PHOSPHOROTHIOATES; SCISSILE SITE; SUBSTRATE SPECIFICITY;

CATALYSIS;

EID: 52949151200     PISSN: 13852728     EISSN: None     Source Type: Journal    
DOI: 10.2174/138527208785161204     Document Type: Review

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