Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics

Journal of Antimicrobial Chemotherapy

Volumn 62, Issue 4, 2008, Pages 730-737

  Zorko, Mateja ^a   Jerala, Roman ^a  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

Author keywords

Bisbiguanide; Isothermal titration calorimetry; Toll like receptor activation inhibition

Indexed keywords

ALEXIDINE; AMPICILLIN; BACTERIUM LIPOPOLYSACCHARIDE; BISBIGUANIDE DERIVATIVE; CHLORAMPHENICOL; CHLORHEXIDINE; LIPOTEICHOIC ACID; NITRIC OXIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DRUG BINDING; FLUORESCENCE ANALYSIS; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MACROPHAGE ACTIVATION; NONHUMAN;

ANIMALS; ANTI-BACTERIAL AGENTS; BIGUANIDES; CELL LINE; CHLORHEXIDINE; GENES, REPORTER; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGE ACTIVATION; MICE; NF-KAPPA B; NITRIC OXIDE; TEICHOIC ACIDS;

EID: 52949098031     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn270     Document Type: Article

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