Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent

Molecular Cancer Therapeutics

Volumn 5, Issue 9, 2006, Pages 2234-2240

  Yip, Kenneth W ^a,b   Ito, Emma ^a,b   Mao, Xinliang ^b   Au, P Y Billie ^a,c   Hedley, David W ^a,b   Mocanu, Joseph D ^a,b   Bastianutto, Carlo ^a,b   Schimmer, Aaron ^a,b   Liu, Fei Fei ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c Advanced Medical Discovery Institute   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALEXIDINE; ANTINEOPLASTIC AGENT; CALCIUM ION; CASPASE 2; CASPASE 8; CASPASE 9; CISPLATIN; DNA; FLUOROURACIL; HOE 33342; TETRAZOLIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN 3T3; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; DNA CONTENT; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; FIBROBLAST; FLOW CYTOMETRY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HYPOPHARYNX CANCER; IN VIVO STUDY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NASOPHARYNX CANCER; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BIGUANIDES; CARCINOMA, SQUAMOUS CELL; CASPASE 2; CASPASE 9; CISPLATIN; ENZYME ACTIVATION; FEMALE; FLUOROURACIL; HUMANS; HYPOPHARYNGEAL NEOPLASMS; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MICE, SCID; MITOCHONDRIAL MEMBRANES; NIH 3T3 CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 33749575031     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0134     Document Type: Article

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