-
1
-
-
40949095655
-
Guide to receptors and channels (GRAC)
-
3rd edn
-
Alexander SPH, Mathie A, Peters JA (2008). Guide to receptors and channels (GRAC), 3rd edn. Br J Pharmacol 153 (Suppl. 2): S1-S209.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 2
-
-
Alexander, S.P.H.1
Mathie, A.2
Peters, J.A.3
-
2
-
-
0023038756
-
QT prolongation and torsade de pointes ventricular tachycardia produced by Ketanserin
-
Aldariz AE, Romero H, Baroni M, Baglivo H, Esper RJ (1986). QT prolongation and torsade de pointes ventricular tachycardia produced by Ketanserin. Pacing Clin Electrophysiol 9: 836-841.
-
(1986)
Pacing Clin Electrophysiol
, vol.9
, pp. 836-841
-
-
Aldariz, A.E.1
Romero, H.2
Baroni, M.3
Baglivo, H.4
Esper, R.J.5
-
3
-
-
2542429602
-
Ketanserin in women with chronic hypertension and underlying thrombophilia
-
Banga FR, Bolte AC, Dekker GA, van Geijn HP (2004). Ketanserin in women with chronic hypertension and underlying thrombophilia. Obstet Gynecol 103: 1084-1087.
-
(2004)
Obstet Gynecol
, vol.103
, pp. 1084-1087
-
-
Banga, F.R.1
Bolte, A.C.2
Dekker, G.A.3
van Geijn, H.P.4
-
4
-
-
0035133633
-
Ketanserin for the treatment of preeclampsia
-
Bolte AC, van Eyck J, Gaffar SF, van Geijn HP, Dekker GA (2001). Ketanserin for the treatment of preeclampsia. J Perinat Med 29: 14-22.
-
(2001)
J Perinat Med
, vol.29
, pp. 14-22
-
-
Bolte, A.C.1
van Eyck, J.2
Gaffar, S.F.3
van Geijn, H.P.4
Dekker, G.A.5
-
5
-
-
0037448785
-
Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels
-
Caballero R, Moreno I, Gonzalez T, Arias C, Valenzuela C, Delpon E et al. (2003). Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels. Circulation 107: 889-895.
-
(2003)
Circulation
, vol.107
, pp. 889-895
-
-
Caballero, R.1
Moreno, I.2
Gonzalez, T.3
Arias, C.4
Valenzuela, C.5
Delpon, E.6
-
6
-
-
33748104214
-
Characterization of recombinant human cardiac KCNQ1/KCNE1 channels (I(Ks)) stably expressed in HEK 293 cells
-
Dong MQ, Lau CP, Gao Z, Tseng GN, Li GR (2006). Characterization of recombinant human cardiac KCNQ1/KCNE1 channels (I(Ks)) stably expressed in HEK 293 cells. J Membr Biol 210: 183-192.
-
(2006)
J Membr Biol
, vol.210
, pp. 183-192
-
-
Dong, M.Q.1
Lau, C.P.2
Gao, Z.3
Tseng, G.N.4
Li, G.R.5
-
9
-
-
0035213865
-
Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels
-
Ficker E, Jarolimek W, Brown AM (2001). Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels. Mol Pharmacol 60: 1343-1348.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1343-1348
-
-
Ficker, E.1
Jarolimek, W.2
Brown, A.M.3
-
10
-
-
0034100396
-
Serotonin and the heart
-
Frishman WH, Grewall P (2000). Serotonin and the heart. Ann Med 32: 195-209.
-
(2000)
Ann Med
, vol.32
, pp. 195-209
-
-
Frishman, W.H.1
Grewall, P.2
-
11
-
-
33745662630
-
+ permeation and block of hERG potassium channels
-
+ permeation and block of hERG potassium channels. J Gen Physiol 128: 55-71.
-
(2006)
J Gen Physiol
, vol.128
, pp. 55-71
-
-
Gang, H.1
Zhang, S.2
-
13
-
-
0036598964
-
Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists
-
Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los AJ, Herndon J et al. (2002). Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists. Curr Top Med Chem 2: 539-558.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 539-558
-
-
Glennon, R.A.1
Metwally, K.2
Dukat, M.3
Ismaiel, A.M.4
De los, A.J.5
Herndon, J.6
-
14
-
-
33645880127
-
Molecular determinants of cocaine block of human ether-a-go-go-related gene potassium channels
-
Guo J, Gang H, Zhang S (2006). Molecular determinants of cocaine block of human ether-a-go-go-related gene potassium channels. J Pharmacol Exp Ther 317: 865-874.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 865-874
-
-
Guo, J.1
Gang, H.2
Zhang, S.3
-
15
-
-
33646850410
-
Population pharmacokinetics of ketanserin in pre-eclamptic patients and its association with antihypertensive response
-
Hanff LM, Visser W, Steegers EA, Vulto AG (2005). Population pharmacokinetics of ketanserin in pre-eclamptic patients and its association with antihypertensive response. Fundam Clin Pharmacol 19: 585-590.
-
(2005)
Fundam Clin Pharmacol
, vol.19
, pp. 585-590
-
-
Hanff, L.M.1
Visser, W.2
Steegers, E.A.3
Vulto, A.G.4
-
16
-
-
0032746775
-
Use-dependent 'agonist' effect of azimilide on the HERG channel
-
Jiang M, Dun W, Fan JS, Tseng GN (1999). Use-dependent 'agonist' effect of azimilide on the HERG channel. J Pharmacol Exp Ther 291: 1324-1336.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1324-1336
-
-
Jiang, M.1
Dun, W.2
Fan, J.S.3
Tseng, G.N.4
-
17
-
-
33646709914
-
Ketanserin, a 5-HT2 antagonist, directly inhibits the ATP-sensitive potassium channel in mouse ventricular myocytes
-
Ju JM, Hwang JH, Piao LH, Park HW, Park JS, Shin DH et al. (2006). Ketanserin, a 5-HT2 antagonist, directly inhibits the ATP-sensitive potassium channel in mouse ventricular myocytes. J Cardiovasc Pharmacol 47: 96-102.
-
(2006)
J Cardiovasc Pharmacol
, vol.47
, pp. 96-102
-
-
Ju, J.M.1
Hwang, J.H.2
Piao, L.H.3
Park, H.W.4
Park, J.S.5
Shin, D.H.6
-
18
-
-
0034914537
-
Open channel block of HERG K(+) channels by vesnarinone
-
Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC (2001). Open channel block of HERG K(+) channels by vesnarinone. Mol Pharmacol 60: 244-253.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 244-253
-
-
Kamiya, K.1
Mitcheson, J.S.2
Yasui, K.3
Kodama, I.4
Sanguinetti, M.C.5
-
19
-
-
0033026763
-
Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels
-
Kiehn J, Thomas D, Karle CA, Schols W, Kubler W (1999). Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels. Naunyn Schmiedebergs Arch Pharmacol 359: 212-219.
-
(1999)
Naunyn Schmiedebergs Arch Pharmacol
, vol.359
, pp. 212-219
-
-
Kiehn, J.1
Thomas, D.2
Karle, C.A.3
Schols, W.4
Kubler, W.5
-
20
-
-
0028959268
-
Ketanserin inhibits the transient outward current in rabbit ventricular myocytes
-
Le Grand B, Marty A, Colpaert FC, John GW (1995a). Ketanserin inhibits the transient outward current in rabbit ventricular myocytes. J Cardiovasc Pharmacol 25: 341-344.
-
(1995)
J Cardiovasc Pharmacol
, vol.25
, pp. 341-344
-
-
Le Grand, B.1
Marty, A.2
Colpaert, F.C.3
John, G.W.4
-
21
-
-
0028868956
-
Investigation of the mechanism by which ketanserin prolongs the duration of the cardiac action potential
-
Le Grand B, Talmant JM, Rieu JP, Patoiseau JF, Colpaert FC, John GW (1995b). Investigation of the mechanism by which ketanserin prolongs the duration of the cardiac action potential. J Cardiovasc Pharmacol 26: 803-809.
-
(1995)
J Cardiovasc Pharmacol
, vol.26
, pp. 803-809
-
-
Le Grand, B.1
Talmant, J.M.2
Rieu, J.P.3
Patoiseau, J.F.4
Colpaert, F.C.5
John, G.W.6
-
23
-
-
32944469464
-
Pharmacological assessment of the freezing, antinociception, and exploratory behavior organized in the ventrolateral periaqueductal gray
-
Luca-Vinhas MC, Macedo CE, Brandao ML (2006). Pharmacological assessment of the freezing, antinociception, and exploratory behavior organized in the ventrolateral periaqueductal gray. Pain 121: 94-104.
-
(2006)
Pain
, vol.121
, pp. 94-104
-
-
Luca-Vinhas, M.C.1
Macedo, C.E.2
Brandao, M.L.3
-
24
-
-
0030960540
-
Randomized single-blind trial of topical ketanserin for healing acceleration of diabetic foot ulcers
-
Martinez-de Jesus FR, Morales-Guzman M, Castaneda M, Perez-Morales A, Garcia-Alonso J, Mendiola-Segura I (1997). Randomized single-blind trial of topical ketanserin for healing acceleration of diabetic foot ulcers. Arch Med Res 28: 95-99.
-
(1997)
Arch Med Res
, vol.28
, pp. 95-99
-
-
Martinez-de Jesus, F.R.1
Morales-Guzman, M.2
Castaneda, M.3
Perez-Morales, A.4
Garcia-Alonso, J.5
Mendiola-Segura, I.6
-
25
-
-
0034710933
-
A structural basis for drug-induced long QT syndrome
-
Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC (2000). A structural basis for drug-induced long QT syndrome. Proc Natl Acad Sci USA 97: 12329-12333.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12329-12333
-
-
Mitcheson, J.S.1
Chen, J.2
Lin, M.3
Culberson, C.4
Sanguinetti, M.C.5
-
26
-
-
0026517078
-
Serotonin increases calcium current in human atrial myocytes via the newly described 5-hydroxytryptamine4 receptors
-
Ouadid H, Seguin J, Dumuis A, Bockaert J, Nargeot J (1992). Serotonin increases calcium current in human atrial myocytes via the newly described 5-hydroxytryptamine4 receptors. Mol Pharmacol 41: 346-351.
-
(1992)
Mol Pharmacol
, vol.41
, pp. 346-351
-
-
Ouadid, H.1
Seguin, J.2
Dumuis, A.3
Bockaert, J.4
Nargeot, J.5
-
27
-
-
33645985140
-
Healing effect of ketanserin on chronic leg ulcers in patients with diabetes
-
Quatresooz P, Kharfi M, Paquet P, Vroome V, Cauwenbergh G, Pierard GE (2006). Healing effect of ketanserin on chronic leg ulcers in patients with diabetes. J Eur Acad Dermatol Venereol 20: 277-281.
-
(2006)
J Eur Acad Dermatol Venereol
, vol.20
, pp. 277-281
-
-
Quatresooz, P.1
Kharfi, M.2
Paquet, P.3
Vroome, V.4
Cauwenbergh, G.5
Pierard, G.E.6
-
29
-
-
33748464784
-
Pharmacologic management of complex regional pain syndrome
-
Rowbotham MC (2006). Pharmacologic management of complex regional pain syndrome. Clin J Pain 22: 425-429.
-
(2006)
Clin J Pain
, vol.22
, pp. 425-429
-
-
Rowbotham, M.C.1
-
31
-
-
0022386591
-
Serotonin and the heart: Effects of ketanserin on myocardial function, heart rate, and arrhythmias
-
Saman S, Thandroyen F, Opie LH (1985). Serotonin and the heart: effects of ketanserin on myocardial function, heart rate, and arrhythmias. J Cardiovasc Pharmacol 7 (Suppl 7): S70-S75.
-
(1985)
J Cardiovasc Pharmacol
, vol.7
, Issue.SUPPL. 7
-
-
Saman, S.1
Thandroyen, F.2
Opie, L.H.3
-
34
-
-
0030025308
-
The inward rectification mechanism of the HERG cardiac potassium channel
-
Smith PL, Baukrowitz T, Yellen G (1996). The inward rectification mechanism of the HERG cardiac potassium channel. Nature 379: 833-836.
-
(1996)
Nature
, vol.379
, pp. 833-836
-
-
Smith, P.L.1
Baukrowitz, T.2
Yellen, G.3
-
36
-
-
0033840413
-
Serotonin antagonism and serotonin antagonists in pregnancy: Role of ketanserin
-
Steyn DW, Odendaal HJ (2000). Serotonin antagonism and serotonin antagonists in pregnancy: role of ketanserin. Obstet Gynecol Surv 55: 582-589.
-
(2000)
Obstet Gynecol Surv
, vol.55
, pp. 582-589
-
-
Steyn, D.W.1
Odendaal, H.J.2
-
38
-
-
0031559897
-
Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241
-
Suessbrich H, Schonherr R, Heinemann SH, Lang F, Busch AE (1997). Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241. FEBS Lett 414: 435-438.
-
(1997)
FEBS Lett
, vol.414
, pp. 435-438
-
-
Suessbrich, H.1
Schonherr, R.2
Heinemann, S.H.3
Lang, F.4
Busch, A.E.5
-
39
-
-
35348955352
-
The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go related gene potassium channels stably expressed in HEK 293 cells
-
Tang Q, Jin MW, Xiang JZ, Dong MQ, Sun HY, Lau CP et al. (2007). The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go related gene potassium channels stably expressed in HEK 293 cells. Biochem Pharmacol 74: 1596-1607.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1596-1607
-
-
Tang, Q.1
Jin, M.W.2
Xiang, J.Z.3
Dong, M.Q.4
Sun, H.Y.5
Lau, C.P.6
-
40
-
-
32244447329
-
Effects of the antifungal antibiotic clotrimazole on human cardiac repolarization potassium currents
-
Tian M, Dong MQ, Chiu SW, Lau CP, Li GR (2006). Effects of the antifungal antibiotic clotrimazole on human cardiac repolarization potassium currents. Br J Pharmacol 147: 289-297.
-
(2006)
Br J Pharmacol
, vol.147
, pp. 289-297
-
-
Tian, M.1
Dong, M.Q.2
Chiu, S.W.3
Lau, C.P.4
Li, G.R.5
-
41
-
-
0029007356
-
HERG, a human inward rectifier in the voltage-gated potassium channel family
-
Trudeau MC, Warmke JW, Ganetzky B, Robertson GA (1995). HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 269: 92-95.
-
(1995)
Science
, vol.269
, pp. 92-95
-
-
Trudeau, M.C.1
Warmke, J.W.2
Ganetzky, B.3
Robertson, G.A.4
-
42
-
-
0037052618
-
The optimal dosage of ketanserin for patients with severe hypertension in pregnancy
-
van Schie DL, de Jeu RM, Steyn DW, Odendaal HJ, van Geijn HP (2002). The optimal dosage of ketanserin for patients with severe hypertension in pregnancy. Eur J Obstet Gynecol Reprod Biol 102: 161-166.
-
(2002)
Eur J Obstet Gynecol Reprod Biol
, vol.102
, pp. 161-166
-
-
van Schie, D.L.1
de Jeu, R.M.2
Steyn, D.W.3
Odendaal, H.J.4
van Geijn, H.P.5
-
43
-
-
0033776519
-
Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel
-
Walker BD, Singleton CB, Tie H, Bursill JA, Wyse KR, Valenzuela SM et al. (2000). Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel. Cardiovasc Res 48: 44-58.
-
(2000)
Cardiovasc Res
, vol.48
, pp. 44-58
-
-
Walker, B.D.1
Singleton, C.B.2
Tie, H.3
Bursill, J.A.4
Wyse, K.R.5
Valenzuela, S.M.6
-
45
-
-
0036188776
-
Dofetilide block involves interactions with open and inactivated states of HERG channels
-
Weerapura M, Hebert TE, Nattel S (2002). Dofetilide block involves interactions with open and inactivated states of HERG channels. Pflugers Arch 443: 520-531.
-
(2002)
Pflugers Arch
, vol.443
, pp. 520-531
-
-
Weerapura, M.1
Hebert, T.E.2
Nattel, S.3
-
46
-
-
2442625443
-
Inactivation gating determines drug potency: A common mechanism for drug blockade of HERG channels
-
Yang BF, Xu DH, Xu CQ, Li Z, Du ZM, Wang HZ et al. (2004). Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels. Acta Pharmacol Sin 25: 554-560.
-
(2004)
Acta Pharmacol Sin
, vol.25
, pp. 554-560
-
-
Yang, B.F.1
Xu, D.H.2
Xu, C.Q.3
Li, Z.4
Du, Z.M.5
Wang, H.Z.6
-
47
-
-
0024409290
-
Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart
-
Zaza A, Malfatto G, Rosen MR (1989). Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart. J Pharmacol Exp Ther 250: 397-405.
-
(1989)
J Pharmacol Exp Ther
, vol.250
, pp. 397-405
-
-
Zaza, A.1
Malfatto, G.2
Rosen, M.R.3
-
48
-
-
0024517702
-
Incidence and clinical relevance of QT prolongation caused by the new selective serotonin antagonist ketanserin
-
Zehender M, Meinertz T, Hohnloser S, Geibel A, Hartung J, Seiler KU et al. (1989). Incidence and clinical relevance of QT prolongation caused by the new selective serotonin antagonist ketanserin. Am J Cardiol 63: 826-832.
-
(1989)
Am J Cardiol
, vol.63
, pp. 826-832
-
-
Zehender, M.1
Meinertz, T.2
Hohnloser, S.3
Geibel, A.4
Hartung, J.5
Seiler, K.U.6
-
49
-
-
0033553504
-
Mechanism of block and identification of the verapamil-binding domain to HERG potassium channels
-
Zhang S, Zhou Z, Gong Q, Makielski JC, January CT (1999). Mechanism of block and identification of the verapamil-binding domain to HERG potassium channels. Circ Res 84: 989-998.
-
(1999)
Circ Res
, vol.84
, pp. 989-998
-
-
Zhang, S.1
Zhou, Z.2
Gong, Q.3
Makielski, J.C.4
January, C.T.5
-
50
-
-
0028060074
-
Ketanserin inhibits depolarization-activated outward potassium current in rat ventricular myocytes
-
Zhang ZH, Boutjdir M, el-Sherif N (1994). Ketanserin inhibits depolarization-activated outward potassium current in rat ventricular myocytes. Circ Res 75: 711-721.
-
(1994)
Circ Res
, vol.75
, pp. 711-721
-
-
Zhang, Z.H.1
Boutjdir, M.2
el-Sherif, N.3
|