Characterization of recombinant human cardiac KCNQ1/KCNE1 channels (I Ks) stably expressed in HEK 293 cells

Journal of Membrane Biology

Volumn 210, Issue 3, 2006, Pages 183-192

  Dong, Ming Qing ^a   Lau, Chu Pak ^a   Gao, Zhan ^a   Tseng, Gea Ny ^b   Li, Gui Rong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electrophysiology; HEK 293 cell; Ion channel; Perforated recording; Recombinant human cardiac KCNQ1 KCNE1; Slowly activating delayed rectifier potassium current

Indexed keywords

BARIUM ION; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CHROMANOL 293B; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPRENALINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N [3 HYDROXY 2,2 DIMETHYL 6 (4,4,4 TRIFLUOROBUTOXY)CHROMAN 4 YL] N METHYLMETHANESULFONAMIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; UNCLASSIFIED DRUG;

ARTICLE; CELL CLONE; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; EMBRYO; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; MEMBRANE CURRENT; MEMBRANE POTENTIAL; PATCH CLAMP; ROOM TEMPERATURE; TEMPERATURE DEPENDENCE; UPREGULATION;

ACTION POTENTIALS; ADRENERGIC BETA-AGONISTS; BARIUM; CELLS, CULTURED; CHROMANS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; HUMANS; ISOPROTERENOL; ISOQUINOLINES; KCNQ1 POTASSIUM CHANNEL; KIDNEY; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN KINASE INHIBITORS; RECOMBINANT PROTEINS; SULFONAMIDES; TRANSFECTION;

EID: 33748104214     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-006-0006-5     Document Type: Article

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