Effects of the antifungal antibiotic clotrimazole on human cardiac repolarization potassium currents

British Journal of Pharmacology

Volumn 147, Issue 3, 2006, Pages 289-297

  Tian, Miao ^a   Dong, Ming Qing ^a   Chiu, Shui Wha ^a   Lau, Chu Pak ^a   Li, Gui Rong ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Clotrimazole; hERG channel; Human cardiac repolarization K + currents; Recombinant human cardiac KCNQ1 KCNE1; Transient outward K + current; Ultra rapidly delayed rectifier K + current

Indexed keywords

ANTIFUNGAL AGENT; CLOTRIMAZOLE; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; HEART ATRIUM; HEART MUSCLE CELL; HEART REPOLARIZATION; HUMAN; HUMAN CELL; IC 50; ION CONDUCTANCE; MOLECULAR CLONING; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; ANTIBIOTICS, ANTIFUNGAL; ANTIFUNGAL AGENTS; CELLS, CULTURED; CLOTRIMAZOLE; DELAYED RECTIFIER POTASSIUM CHANNELS; ETHER-A-GO-GO POTASSIUM CHANNELS; HEART; HUMANS; KCNQ1 POTASSIUM CHANNEL; MIDDLE AGED; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 32244447329     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706590     Document Type: Article

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