메뉴 건너뛰기




Volumn 70, Issue 5, 2008, Pages 257-267

Adrenarche: Postnatal adrenal zonation and hormonal and metabolic regulation

Author keywords

Adrenal androgens; Adrenal cortex medulla interaction; Adrenarche, premature; Estrogen receptor; GH IGF system

Indexed keywords

AROMATASE; CORTICOTROPIN; CYTOCHROME B5; CYTOCHROME P450C17; ESTRADIOL; GROWTH HORMONE; HYDROXYSTEROID DEHYDROGENASE; INSULIN; PRASTERONE; PRASTERONE SULFATE; SOMATOMEDIN; STEROID 17,20 LYASE; SULFOTRANSFERASE;

EID: 52549085934     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000157871     Document Type: Short Survey
Times cited : (54)

References (62)
  • 2
    • 0014464099 scopus 로고
    • The involution of the foetal adrenal cortex. A light microscopic study
    • Bech K, Tygstrup I, Nerup J: The involution of the foetal adrenal cortex. A light microscopic study. Acta Pathol Microbiol Scand 1969;76:391-400.
    • (1969) Acta Pathol Microbiol Scand , vol.76 , pp. 391-400
    • Bech, K.1    Tygstrup, I.2    Nerup, J.3
  • 3
    • 0017201426 scopus 로고
    • Unconjugated dehydroepiandrosterone plasma levels in normal subjects from birth to adolescence in humans: For the use of a sensitive radioimmunoassay
    • dePeretti E, Forest MG: Unconjugated dehydroepiandrosterone plasma levels in normal subjects from birth to adolescence in humans: for the use of a sensitive radioimmunoassay. J Clin Endocrinol Metab 1976;43:982-991.
    • (1976) J Clin Endocrinol Metab , vol.43 , pp. 982-991
    • dePeretti, E.1    Forest, M.G.2
  • 4
    • 0034503112 scopus 로고    scopus 로고
    • Premature adrenarche. Normal variant or forerunner of adult disease?
    • Ibáñez L, DiMartino-Nardi J, Potau N, Saenger P: Premature adrenarche. Normal variant or forerunner of adult disease? Endocr Rev 2000;21:671-696.
    • (2000) Endocr Rev , vol.21 , pp. 671-696
    • Ibáñez, L.1    DiMartino-Nardi, J.2    Potau, N.3    Saenger, P.4
  • 5
    • 17844368603 scopus 로고    scopus 로고
    • Urinary markers of adrenarche: Reference values in healthy subjects, aged 3-18 years
    • Remer T, Boye KR, Hartmann MF, Wudy SA: Urinary markers of adrenarche: reference values in healthy subjects, aged 3-18 years. J Clin Endocrinol Metab 2005;90:2015-2021.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2015-2021
    • Remer, T.1    Boye, K.R.2    Hartmann, M.F.3    Wudy, S.A.4
  • 6
    • 0030926557 scopus 로고    scopus 로고
    • Developmental and functional biology of the primate fetal adrenal cortex
    • Mesiano S, Jaffe RB: Developmental and functional biology of the primate fetal adrenal cortex. Endocr Rev 1997;18:378-403.
    • (1997) Endocr Rev , vol.18 , pp. 378-403
    • Mesiano, S.1    Jaffe, R.B.2
  • 7
    • 0036637499 scopus 로고    scopus 로고
    • Recent insights into organogenesis of the adrenal cortex
    • Keegan CE, Hammer GD: Recent insights into organogenesis of the adrenal cortex. Trends Endocrinol Metab 2002;13:200-208.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 200-208
    • Keegan, C.E.1    Hammer, G.D.2
  • 8
    • 14244270348 scopus 로고    scopus 로고
    • Minireview: Transcriptional regulation of adrenocortical development
    • Hammer GD, Parker KL, Schimmer BP: Minireview: transcriptional regulation of adrenocortical development. Endocrinology 2005;146:1018-1024.
    • (2005) Endocrinology , vol.146 , pp. 1018-1024
    • Hammer, G.D.1    Parker, K.L.2    Schimmer, B.P.3
  • 9
    • 0027423246 scopus 로고
    • Localization of cytochrome P450 cholesterol side chain cleavage, cytochrome P450 17α-lyase and 3β-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: Reappraisal of functional zonation
    • Mesiano S, Coulter CL, Jaffe RB: Localization of cytochrome P450 cholesterol side chain cleavage, cytochrome P450 17α-lyase and 3β-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: reappraisal of functional zonation. J Clin Endocrinol Metab 1993;77:1184-1189.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1184-1189
    • Mesiano, S.1    Coulter, C.L.2    Jaffe, R.B.3
  • 10
    • 0033031741 scopus 로고    scopus 로고
    • Proliferation and apoptosis in the human adrenal cortex during the fetal and perinatal periods: Implications for growth and remodeling
    • Spencer SJ, Mesiano S, Lee JY, Jaffe RB: Proliferation and apoptosis in the human adrenal cortex during the fetal and perinatal periods: implications for growth and remodeling. J Clin Endocrinol Metab 1999;84:1110-1115.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1110-1115
    • Spencer, S.J.1    Mesiano, S.2    Lee, J.Y.3    Jaffe, R.B.4
  • 11
    • 0034493776 scopus 로고    scopus 로고
    • Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: Immunohistochemical studies
    • Suzuki T, Sasano H, Takeyama J, Kaneko C, Freije W, Carr R, Rainey WE: Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies. Clin Endocrinol (Oxf) 2000;53:739-747.
    • (2000) Clin Endocrinol (Oxf) , vol.53 , pp. 739-747
    • Suzuki, T.1    Sasano, H.2    Takeyama, J.3    Kaneko, C.4    Freije, W.5    Carr, R.6    Rainey, W.E.7
  • 15
    • 0024064517 scopus 로고
    • Molecular biology of steroid hormone synthesis
    • Miller WL: Molecular biology of steroid hormone synthesis. Endocr Rev 1988;9:295-318.
    • (1988) Endocr Rev , vol.9 , pp. 295-318
    • Miller, W.L.1
  • 16
    • 0019874673 scopus 로고
    • Microsomal cytochrome P-450 from neonatal pig testis: Two enzymatic activities (17α-hydroxylase and c17,20-lyase) associated with one protein
    • Nkajin S, Shively JE, Yuan P, Hall PF: Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17α-hydroxylase and c17,20-lyase) associated with one protein. Biochemistry 1981;20:4037-4042.
    • (1981) Biochemistry , vol.20 , pp. 4037-4042
    • Nkajin, S.1    Shively, J.E.2    Yuan, P.3    Hall, P.F.4
  • 17
    • 0031032651 scopus 로고    scopus 로고
    • The regulation of 17,20 lyase activity
    • Miller WL, Auchus RJ, Geller DH: The regulation of 17,20 lyase activity. Steroids 1997;64:133-142.
    • (1997) Steroids , vol.64 , pp. 133-142
    • Miller, W.L.1    Auchus, R.J.2    Geller, D.H.3
  • 19
    • 0032588511 scopus 로고    scopus 로고
    • Decrease in the expression of the 3β-hydroxysteroid dehydrogenase gene in human adrenal tissue during prepuberty and early puberty. Implications to the mechanism of adrenarche
    • Dardis A, Saraco N, Rivarola MA, Belgorosky A: Decrease in the expression of the 3β-hydroxysteroid dehydrogenase gene in human adrenal tissue during prepuberty and early puberty. Implications to the mechanism of adrenarche. Pediatr Res 1999;45:384-388.
    • (1999) Pediatr Res , vol.45 , pp. 384-388
    • Dardis, A.1    Saraco, N.2    Rivarola, M.A.3    Belgorosky, A.4
  • 20
    • 4444258175 scopus 로고    scopus 로고
    • The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. Implications for the control of adrenal functional zonation
    • Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR, Rainey WE: The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. Implications for the control of adrenal functional zonation. J Biol Chem 2004;279:37622-37630.
    • (2004) J Biol Chem , vol.279 , pp. 37622-37630
    • Bassett, M.H.1    Suzuki, T.2    Sasano, H.3    De Vries, C.J.4    Jimenez, P.T.5    Carr, B.R.6    Rainey, W.E.7
  • 22
    • 0030047248 scopus 로고    scopus 로고
    • Regulation of the acute production of steroids in steroidogenic cells
    • Stocco DM, Clark BJ: Regulation of the acute production of steroids in steroidogenic cells. Endocr Rev 1996;17:221-244.
    • (1996) Endocr Rev , vol.17 , pp. 221-244
    • Stocco, D.M.1    Clark, B.J.2
  • 23
    • 0030996897 scopus 로고    scopus 로고
    • Diminished adrenal androgen secretion in familial glucocorticoid deficiency implicates a significant role for ACTH in the induction of adrenarche
    • Weber A, Clark AJ, Perry LA, Honour JW, Savage MO: Diminished adrenal androgen secretion in familial glucocorticoid deficiency implicates a significant role for ACTH in the induction of adrenarche. Clin Endocrinol (Oxf) 1997;46:431-437.
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 431-437
    • Weber, A.1    Clark, A.J.2    Perry, L.A.3    Honour, J.W.4    Savage, M.O.5
  • 24
    • 0018405248 scopus 로고
    • Adrenocortical function and puberty, serum ACTH cortisol and dehydroepiandrosterone in girls and boys
    • Apter D, Pakkerinen A, Hammond GI, Vihko R: Adrenocortical function and puberty, serum ACTH cortisol and dehydroepiandrosterone in girls and boys. Acta Pediatr Scand 1979;69:599-606.
    • (1979) Acta Pediatr Scand , vol.69 , pp. 599-606
    • Apter, D.1    Pakkerinen, A.2    Hammond, G.I.3    Vihko, R.4
  • 25
    • 0029818083 scopus 로고    scopus 로고
    • Insulin-like growth factors enhance steroidogenic enzyme and corticotrophin receptor messenger ribonucleic acid levels and corticotrophin steroidogenic responsiveness in cultured human adrenocortical cells
    • L'Allemand D, Penhoat A, Lebrethon MC, Ardevol R, Baehr V, Oelkers W, Saez JM: Insulin-like growth factors enhance steroidogenic enzyme and corticotrophin receptor messenger ribonucleic acid levels and corticotrophin steroidogenic responsiveness in cultured human adrenocortical cells. J Clin Endocrinol Metab 1996;81:3892-3897.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3892-3897
    • L'Allemand, D.1    Penhoat, A.2    Lebrethon, M.C.3    Ardevol, R.4    Baehr, V.5    Oelkers, W.6    Saez, J.M.7
  • 26
    • 24344486044 scopus 로고    scopus 로고
    • Expression of the IGF system in human adrenal tissues from early infancy to late puberty: Implications for the development of adrenarche
    • Baquedano MS, Berensztein E, Saraco N, Dorn GV, de Davila MT, Rivarola MA, Belgorosky A: Expression of the IGF system in human adrenal tissues from early infancy to late puberty: implications for the development of adrenarche. Pediatr Res 2005;58:451-458.
    • (2005) Pediatr Res , vol.58 , pp. 451-458
    • Baquedano, M.S.1    Berensztein, E.2    Saraco, N.3    Dorn, G.V.4    de Davila, M.T.5    Rivarola, M.A.6    Belgorosky, A.7
  • 27
    • 0023919308 scopus 로고
    • Changes in serum insulin concentration during puberty and their relationship to growth hormone
    • Hindmarsh P, Di Silvio L, Pringle PJ, Kurtz AB, Brook CGD: Changes in serum insulin concentration during puberty and their relationship to growth hormone. Clin Endocrinol 1988;21:381-388.
    • (1988) Clin Endocrinol , vol.21 , pp. 381-388
    • Hindmarsh, P.1    Di Silvio, L.2    Pringle, P.J.3    Kurtz, A.B.4    Brook, C.G.D.5
  • 29
    • 0031790829 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-I levels are strongly associated with insulin sensitivity and obesity in early pubertal children
    • Travers SH, Labarta JI, Gargosky SE, Rosenfeld RG, Jeffers BW, Eckel RH: Insulin-like growth factor binding protein-I levels are strongly associated with insulin sensitivity and obesity in early pubertal children. J Clin Endocrinol Metab 1998;83:1935-1939.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1935-1939
    • Travers, S.H.1    Labarta, J.I.2    Gargosky, S.E.3    Rosenfeld, R.G.4    Jeffers, B.W.5    Eckel, R.H.6
  • 30
    • 0028293598 scopus 로고
    • Serum Insulin-like growth factor-1 in 1,030 healthy children, adolescents and adults: Relation to age, sex, stage of puberty, testicular size, and body mass index
    • Juul A, Bang P, Hertel NT, Main K, Dalgaard P, Jorgensen K, Muller J, Hall K, Skakkebae NS: Serum Insulin-like growth factor-1 in 1,030 healthy children, adolescents and adults: relation to age, sex, stage of puberty, testicular size, and body mass index. J Clin Endocrinol Metab 1994;78:744-752.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 744-752
    • Juul, A.1    Bang, P.2    Hertel, N.T.3    Main, K.4    Dalgaard, P.5    Jorgensen, K.6    Muller, J.7    Hall, K.8    Skakkebae, N.S.9
  • 31
    • 0033457910 scopus 로고    scopus 로고
    • Insulin the other anabolic hormone of puberty
    • Caprio S: Insulin the other anabolic hormone of puberty. Acta Paediatr Suppl 1999;433:84-87.
    • (1999) Acta Paediatr Suppl , vol.433 , pp. 84-87
    • Caprio, S.1
  • 33
    • 0028983095 scopus 로고
    • Gender and Tanner stage differences in body composition and insulin sensitivity in early pubertal children
    • Travers SH, Jeffers BW, Bloch CA, Hill JO, Eckel RH: Gender and Tanner stage differences in body composition and insulin sensitivity in early pubertal children. J Clin Endocrinol Metab 1995;80:172-178.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 172-178
    • Travers, S.H.1    Jeffers, B.W.2    Bloch, C.A.3    Hill, J.O.4    Eckel, R.H.5
  • 34
    • 0033887498 scopus 로고    scopus 로고
    • Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model
    • Hoffman RP, Vicini P, Sivitz WI, Cobelli C: Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model. Pediatr Res 2000;48:384-388.
    • (2000) Pediatr Res , vol.48 , pp. 384-388
    • Hoffman, R.P.1    Vicini, P.2    Sivitz, W.I.3    Cobelli, C.4
  • 35
    • 0036962120 scopus 로고    scopus 로고
    • Relationship between the GH/IGF-1, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal boys
    • Guercio G, Rivarola MA, Chaler E, Maceiras M, Belgorosky A: Relationship between the GH/IGF-1, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal boys. J Clin Endocrinol Metab 2002;87:1162-1169.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1162-1169
    • Guercio, G.1    Rivarola, M.A.2    Chaler, E.3    Maceiras, M.4    Belgorosky, A.5
  • 36
    • 0025726166 scopus 로고
    • Sexual dimorphism in insulin sensitivity in adolescents with insulin dependent diabetes mellitus
    • Arslanian SA, Heil BV, Becker DJ, Drash AL: Sexual dimorphism in insulin sensitivity in adolescents with insulin dependent diabetes mellitus. J Clin Endocrinol Metab 1991;72:920-926.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 920-926
    • Arslanian, S.A.1    Heil, B.V.2    Becker, D.J.3    Drash, A.L.4
  • 37
    • 0037340436 scopus 로고    scopus 로고
    • Relationship between the GH/IGF-1, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal girls
    • Guercio G, Rivarola MA, Chaler E, Maceiras M, Belgorosky A: Relationship between the GH/IGF-1, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal girls. J Clin Endocrinol Metab 2003;88:1389-1393.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1389-1393
    • Guercio, G.1    Rivarola, M.A.2    Chaler, E.3    Maceiras, M.4    Belgorosky, A.5
  • 39
  • 41
  • 43
    • 0027421792 scopus 로고
    • Interaction of insulin-like growth factor-II and estradiol directs steroidogenesis in the human fetal adrenal towards dehydroepiandrosterone sulfate production
    • Mesiano S, Jaffe RB: Interaction of insulin-like growth factor-II and estradiol directs steroidogenesis in the human fetal adrenal towards dehydroepiandrosterone sulfate production. J Clin Endocrinol Metab 1993;77:754-758.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 754-758
    • Mesiano, S.1    Jaffe, R.B.2
  • 44
    • 0031838965 scopus 로고    scopus 로고
    • Effect of estradiol on DHEAS production in the human adrenocortical cell line, H295R
    • Gell JS, Oh J, Rainey E, Carr BR: Effect of estradiol on DHEAS production in the human adrenocortical cell line, H295R. J Soc Gynecol Invest 1998;5:144-148.
    • (1998) J Soc Gynecol Invest , vol.5 , pp. 144-148
    • Gell, J.S.1    Oh, J.2    Rainey, E.3    Carr, B.R.4
  • 47
    • 0033305247 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone: A potent androgen secretagogue in girls with hyperandrogenism alter precocious pubarche
    • Ibáñez L, Potau N, Marcos MV, de Zegher F: Corticotropin-releasing hormone: a potent androgen secretagogue in girls with hyperandrogenism alter precocious pubarche. J Clin Endocrinol Metab 1999;84:4602-4606.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4602-4606
    • Ibáñez, L.1    Potau, N.2    Marcos, M.V.3    de Zegher, F.4
  • 48
    • 27244432905 scopus 로고    scopus 로고
    • Developmental origins of health and disease
    • Gillman MW: Developmental origins of health and disease. N Engl J Med 2005;353:1848-1850.
    • (2005) N Engl J Med , vol.353 , pp. 1848-1850
    • Gillman, M.W.1
  • 49
    • 0031769471 scopus 로고    scopus 로고
    • Precocious pubarche, hyperinsulinism, and ovarian hyperandrogensim in girls: Relation to reduced fetal growth
    • Ibañez L, Potau N, Francois I, de Zegher F: Precocious pubarche, hyperinsulinism, and ovarian hyperandrogensim in girls: relation to reduced fetal growth. J Clin Endocrinol Metab 1998;83:3558-3562.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3558-3562
    • Ibañez, L.1    Potau, N.2    Francois, I.3    de Zegher, F.4
  • 50
    • 1242351792 scopus 로고    scopus 로고
    • Premature pubarche as an indicator of how body weight influences the onset of adrenarche
    • Charkaluk M-L, Trivin C, Brauner R: Premature pubarche as an indicator of how body weight influences the onset of adrenarche. Eur J Pediatr 2004;163:89-93.
    • (2004) Eur J Pediatr , vol.163 , pp. 89-93
    • Charkaluk, M.-L.1    Trivin, C.2    Brauner, R.3
  • 51
    • 0033305392 scopus 로고    scopus 로고
    • The role of insulin sensitivity, insulin-like growth factor I (IGF-I) and IGF-binding protein-1 and -3 in the hyperandrogenism of African-American and Caribbean Hispanic girls with premature adrenarche
    • Vuguin P, Linder B, Rosenfeld RG, Saenger P, DiMartino-Nardi J: The role of insulin sensitivity, insulin-like growth factor I (IGF-I) and IGF-binding protein-1 and -3 in the hyperandrogenism of African-American and Caribbean Hispanic girls with premature adrenarche. J Clin Endocrinol Metab 1999;84:2037-2042.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2037-2042
    • Vuguin, P.1    Linder, B.2    Rosenfeld, R.G.3    Saenger, P.4    DiMartino-Nardi, J.5
  • 52
    • 4544323736 scopus 로고    scopus 로고
    • Ibañez l, Valls C, Marcos MV, Ong K, Dunger DB, De Zegher F: Insulin sensitization for girls with precocious pubarche and with risk for polycystic ovary syndrome: effects of prepubertal initiation and postpubertal discontinuation of metformin treatment. J Clin Endocrinol Metab 2004;89:4331-4337.
    • Ibañez l, Valls C, Marcos MV, Ong K, Dunger DB, De Zegher F: Insulin sensitization for girls with precocious pubarche and with risk for polycystic ovary syndrome: effects of prepubertal initiation and postpubertal discontinuation of metformin treatment. J Clin Endocrinol Metab 2004;89:4331-4337.
  • 53
    • 0036146435 scopus 로고    scopus 로고
    • Elevated free IGF-1 levels in prepubertal Hispanic girls with premature adrenarche: Relationship with hyperandrogenism and insulin sensitivity
    • Silfen ME, Manibo AM, Ferin M, McMahon DJ, Levine LS, Oberfield SE: Elevated free IGF-1 levels in prepubertal Hispanic girls with premature adrenarche: relationship with hyperandrogenism and insulin sensitivity. J Clin Endocrinol Metab 2002;87:398-403.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 398-403
    • Silfen, M.E.1    Manibo, A.M.2    Ferin, M.3    McMahon, D.J.4    Levine, L.S.5    Oberfield, S.E.6
  • 54
    • 0035021518 scopus 로고    scopus 로고
    • Circulating plasma leptin and IGF-1 levels in girls with premature adrenarche: Potential implications of a preliminary study
    • Cizza G, Dorn L, Lotsikas A, Rotenstein D, Chrousos G: Circulating plasma leptin and IGF-1 levels in girls with premature adrenarche: potential implications of a preliminary study. Horm Metab Res 2001;33:138-143.
    • (2001) Horm Metab Res , vol.33 , pp. 138-143
    • Cizza, G.1    Dorn, L.2    Lotsikas, A.3    Rotenstein, D.4    Chrousos, G.5
  • 55
    • 0344177202 scopus 로고    scopus 로고
    • Fat distribution in non-obese girls with and without precocious pubarche: Central adiposity related to insulinaemia and androgenaemia from prepuberty to postmenarche
    • Ibañez L, Ong K, de Zegher F, Marcos MV, del Rio L, Dunger DB: Fat distribution in non-obese girls with and without precocious pubarche: central adiposity related to insulinaemia and androgenaemia from prepuberty to postmenarche. Clin Endocr 2003;58:372-379.
    • (2003) Clin Endocr , vol.58 , pp. 372-379
    • Ibañez, L.1    Ong, K.2    de Zegher, F.3    Marcos, M.V.4    del Rio, L.5    Dunger, D.B.6
  • 56
    • 0033306894 scopus 로고    scopus 로고
    • Role of nutritional status in the regulation of adrenarche
    • Remer T, Manz F: Role of nutritional status in the regulation of adrenarche. J Clin Endocrinol Metab 1999;84:3396-3944.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3396-3944
    • Remer, T.1    Manz, F.2
  • 57
    • 0034456536 scopus 로고    scopus 로고
    • Effect of leptin on CYP17 enzymatic activities in human adrenal cells: New insight in the onset of adrenarche
    • Biason-Lauber A, Zachmann M, Schoenle EJ: Effect of leptin on CYP17 enzymatic activities in human adrenal cells: new insight in the onset of adrenarche. Endocrinology 2000;141:1446-1454.
    • (2000) Endocrinology , vol.141 , pp. 1446-1454
    • Biason-Lauber, A.1    Zachmann, M.2    Schoenle, E.J.3
  • 58
    • 0036227476 scopus 로고    scopus 로고
    • Associations between body mass, leptin, IGF-1, and circulating adrenal androgens in children with obesity and premature adrenarche
    • L'Allemand D, Schmidt S, Rousson V, Brabant G, Gasser T, Grüters A: Associations between body mass, leptin, IGF-1, and circulating adrenal androgens in children with obesity and premature adrenarche. Eur J Endocrinol 2002;146:537-543.
    • (2002) Eur J Endocrinol , vol.146 , pp. 537-543
    • L'Allemand, D.1    Schmidt, S.2    Rousson, V.3    Brabant, G.4    Gasser, T.5    Grüters, A.6
  • 59
    • 33947530021 scopus 로고    scopus 로고
    • Identifying children at risk for polycystic ovary syndrome
    • Rosenfield RL: Identifying children at risk for polycystic ovary syndrome. J Clin Endocrinol Metab 2007;92:787-796.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 787-796
    • Rosenfield, R.L.1
  • 61
    • 0015723935 scopus 로고
    • The prepuberal and puberal growth of the adrenal (adrenarche)
    • Dhom G: The prepuberal and puberal growth of the adrenal (adrenarche). Beitr Pathol 1973;150:357-377.
    • (1973) Beitr Pathol , vol.150 , pp. 357-377
    • Dhom, G.1
  • 62
    • 0017340513 scopus 로고
    • Secretion of the adrenal androgen, dehydroepiandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities
    • Reiter EO, Fuldauer VG, Root AW: Secretion of the adrenal androgen, dehydroepiandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities. J Pediatr 1977;90:766-770.
    • (1977) J Pediatr , vol.90 , pp. 766-770
    • Reiter, E.O.1    Fuldauer, V.G.2    Root, A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.