The roles of insulin sensitivity, insulin-like growth factor I (IGF-I), and IGF-binding protein-1 and -3 in the hyperandrogenism of African-American and Caribbean Hispanic girls with premature adrenarche

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 6, 1999, Pages 2037-2042

  Vuguin, Patricia ^a   Linder, Barbara ^a   Rosenfeld, Ron G ^b   Saenger, Paul ^a   DiMartino Nardi, Joan ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADRENARCHE; ARTICLE; CARIBBEAN ISLANDS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPERANDROGENISM; INSULIN RESISTANCE; INSULIN SENSITIVITY; NEGRO; PRIORITY JOURNAL;

EID: 0033305392     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.84.6.2037     Document Type: Article

References (46)

1. Premature adrenarche: A normal variant of puberty
2. Adrenarche: Changing adrenal response to adrenocorticotropin
3. Absence of nonclassical congenital adrenal hyperplasia in patients with precocious adrenarche
4. Premature pubarche
5. Benign premature adrenarche: Clinical features and serum steroid levels
6. Natural history of premature pubarche: An auxological study
7. Postpubertal outcome in girls diagnosed of premature pubarche during childhood. Increased frequency of functional ovarian hyperandrogenism
8. The insulin like growth factor system in normal and abnormal human ovarian follicle development
9. Expression of insulin like growth factor (IGF) IGF-binding protein and IGF-receptor messenger ribonucleic acids in normal and polycystic ovaries
10. Evidence that idiopathic functional adrenal hyperandrogenism is caused by dysregulation of adrenal steroidogenesis and that hyperinsulinemia may be involved
11. The central role of obesity (hyperinsulinemia) in the pathogenesis of polycystic ovary syndrome
12. Hyperinsulinemia in postpubertal girls with a history of premature pubarche and functional ovarian hyperandrogenism
13. Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: Relevance to the development phase of polycystic ovarian syndrome
14. Decreased insulin sensitivity in prepubertal girls with premature adrenarche and acanthosis nigricans
15. Hormonal findings in African-American and Caribbean Hispanic girls with premature adrenarche: Implications for polycystic ovarian syndrome
16. Genetic defects of steroidogenesis in premature pubarche
17. Standardized percentile curves of body mass index for children and adolescents
18. Toward physiological understanding of glucose tolerance minimal model approach
19. The modified minimal model: Application to measurement of insulin sensitivity in children
20. Normative data for adrenal steroidogenesis in a healthy pediatric population: Age and sex related changes after adrenocorticotropin stimulation
21. Effects of ACTH, insulin and insulin like growth factor I on guinea pig adrenal fasciculata-glomerulosa cells
22. Insulin as a regulator of androgen biosynthesis by cultured rat ovarian cells: Cellular mechanism(s) underlying physiological and pharmacological hormonal actions
23. Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from woman with hyperandrogenism
24. The gonadotropic functions of insulin
25. Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells
26. The effects of insulin and growth hormone on the release of somatomedin by the isolated rat liver
27. Dose response characteristics for suppression of low molecular weight plasma insulin like growth factor binding protein by insulin
28. Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche
29. Assessment of insulin sensitivity in vivo
30. Modified protocols improve insulin sensitivity estimation using the minimal model
31. Ethnicity and polycystic ovary syndrome are associated with independent and additive decreases in insulin action in Caribbean-Hispanic women
32. Increased prevalence of polycystic ovarian disease in Hispanic women
33. Non-insulin dependent diabetes mellitus in Black and White Americans
34. Insulin secretion and sensitivity in black vs. white prepubertal healthy children
35. Insulin resistance obesity, and related disorders among black adolescents
36. Differences in the in vivo insulin secretion and sensitivity of healthy black vs. white adolescents
37. Inhibition of sex hormone binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactin
38. Sex hormone-binding globulin: A marker for hyperinsulinemia and/or insulin resistance
39. Insulin regulates the serum levels of low molecular weight insulin like growth factor-binding protein
40. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovarian syndrome
41. Pituitary ovarian response to naferelin testing in the polycystic ovary syndrome
42. Decreases in ovarian cytochrome P450 c17α activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
43. Serine phosphorylation of human P450 C17 increases 17,20-lyase activity: Implications for adrenarche and the polycystic ovary syndrome
44. Hyperandrogenic anovulation (PCOS) a unique disorder of insulin action associated with an increased risk of non-insulin dependent diabetes mellitus
45. Secondary sexual characteristics and menses in young girls seen in office practice: A study from the pediatric research office settings network