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Volumn 45, Issue 4, 2008, Pages 267-275

Erythropoietic Agents and the Elderly

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANEMIC AGENT; CNTO 530; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; ERYTHROPOIETIC AGENT; ERYTHROPOIETIN; ERYTHROPOIETIN MIMETIC PEPTIDE 1; ERYTHROPOIETIN RECEPTOR; FG 2216; FG 4539; FG 4592; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; K 11706; MIRCERA; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PLACEBO; PROLINE HYDROXYLASE INHIBITOR; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 52049124252     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2008.06.007     Document Type: Article
Times cited : (13)

References (107)
  • 1
    • 0023868741 scopus 로고
    • Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization
    • Koury S.T., Bondurant M.C., and Koury M.J. Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization. Blood 71 (1988) 524-527
    • (1988) Blood , vol.71 , pp. 524-527
    • Koury, S.T.1    Bondurant, M.C.2    Koury, M.J.3
  • 2
    • 0025912710 scopus 로고
    • Localization of cells producing erythropoietin in murine liver by in situ hybridization
    • Koury S.T., Bondurant M.C., Koury M.J., and Semenza G.L. Localization of cells producing erythropoietin in murine liver by in situ hybridization. Blood 77 (1991) 2497-2503
    • (1991) Blood , vol.77 , pp. 2497-2503
    • Koury, S.T.1    Bondurant, M.C.2    Koury, M.J.3    Semenza, G.L.4
  • 3
    • 0024563574 scopus 로고
    • Expression cloning of the murine erythropoietin receptor
    • D'Andrea A.D., Lodish H.F., and Wong G.G. Expression cloning of the murine erythropoietin receptor. Cell 57 (1989) 277-285
    • (1989) Cell , vol.57 , pp. 277-285
    • D'Andrea, A.D.1    Lodish, H.F.2    Wong, G.G.3
  • 4
    • 0025343574 scopus 로고
    • Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells
    • Koury M.J., and Bondurant M.C. Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science 248 (1990) 378-381
    • (1990) Science , vol.248 , pp. 378-381
    • Koury, M.J.1    Bondurant, M.C.2
  • 5
    • 0027360191 scopus 로고
    • Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production
    • Kelley L.L., Koury M.J., Bondurant M.C., Koury S.T., Sawyer S.T., and Wickrema A. Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production. Blood 82 (1993) 2340-2352
    • (1993) Blood , vol.82 , pp. 2340-2352
    • Kelley, L.L.1    Koury, M.J.2    Bondurant, M.C.3    Koury, S.T.4    Sawyer, S.T.5    Wickrema, A.6
  • 6
    • 0030050404 scopus 로고    scopus 로고
    • Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis
    • Lin C.S., Lim S.K., D'Agati V., and Costantini F. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev 10 (1996) 154-164
    • (1996) Genes Dev , vol.10 , pp. 154-164
    • Lin, C.S.1    Lim, S.K.2    D'Agati, V.3    Costantini, F.4
  • 7
    • 22544478796 scopus 로고    scopus 로고
    • The negative regulation of red cell mass by neocytolysis: physiologic and pathophysiologic manifestations
    • Rice L., and Alfrey C.P. The negative regulation of red cell mass by neocytolysis: physiologic and pathophysiologic manifestations. Cell Physiol Biochem 15 (2005) 245-250
    • (2005) Cell Physiol Biochem , vol.15 , pp. 245-250
    • Rice, L.1    Alfrey, C.P.2
  • 9
    • 0024557613 scopus 로고
    • Expression of specific high-affinity binding sites for erythropoietin on rat and mouse megakaryocytes
    • Fraser J.K., Tan A.S., Lin F.K., and Berridge M.V. Expression of specific high-affinity binding sites for erythropoietin on rat and mouse megakaryocytes. Exp Hematol 17 (1989) 10-16
    • (1989) Exp Hematol , vol.17 , pp. 10-16
    • Fraser, J.K.1    Tan, A.S.2    Lin, F.K.3    Berridge, M.V.4
  • 10
    • 0035064310 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture
    • Nagai A., Nakagawa E., Choi H.B., Hatori K., Kobayashi S., and Kim S.U. Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture. J Neuropathol Exp Neurol 60 (2001) 386-392
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 386-392
    • Nagai, A.1    Nakagawa, E.2    Choi, H.B.3    Hatori, K.4    Kobayashi, S.5    Kim, S.U.6
  • 11
    • 0032824560 scopus 로고    scopus 로고
    • Inactivation of erythropoietin leads to defects in cardiac morphogenesis
    • Wu H., Lee S.H., Gao J., Liu X., and Iruela-Arispe M.L. Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development 126 16 (1999) 3597-3605
    • (1999) Development , vol.126 , Issue.16 , pp. 3597-3605
    • Wu, H.1    Lee, S.H.2    Gao, J.3    Liu, X.4    Iruela-Arispe, M.L.5
  • 12
    • 0032566597 scopus 로고    scopus 로고
    • Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis
    • Yasuda Y., Masuda S., Chikuma M., Inoue K., Nagao M., and Sasaki R. Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis. J Biol Chem 273 (1998) 25381-25387
    • (1998) J Biol Chem , vol.273 , pp. 25381-25387
    • Yasuda, Y.1    Masuda, S.2    Chikuma, M.3    Inoue, K.4    Nagao, M.5    Sasaki, R.6
  • 14
    • 0035525744 scopus 로고    scopus 로고
    • Erythropoietin expression in primary rat Sertoli and peritubular myoid cells
    • Magnanti M., Gandini O., Giuliani L., Gazzaniga P., Marti H.H., Gradilone A., et al. Erythropoietin expression in primary rat Sertoli and peritubular myoid cells. Blood 98 (2001) 2872-2874
    • (2001) Blood , vol.98 , pp. 2872-2874
    • Magnanti, M.1    Gandini, O.2    Giuliani, L.3    Gazzaniga, P.4    Marti, H.H.5    Gradilone, A.6
  • 15
    • 33746137372 scopus 로고    scopus 로고
    • Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise
    • Brines M., and Cerami A. Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise. Kidney Int 70 (2006) 246-250
    • (2006) Kidney Int , vol.70 , pp. 246-250
    • Brines, M.1    Cerami, A.2
  • 16
    • 34249056816 scopus 로고    scopus 로고
    • Are erythropoietin receptors expressed in tumors?. Facts and fiction-More careful studies are needed
    • Agarwal N., Gordeuk V.R., and Prchal J.T. Are erythropoietin receptors expressed in tumors?. Facts and fiction-More careful studies are needed. J Clin Oncol 25 (2007) 1813-1814
    • (2007) J Clin Oncol , vol.25 , pp. 1813-1814
    • Agarwal, N.1    Gordeuk, V.R.2    Prchal, J.T.3
  • 17
    • 41549101701 scopus 로고    scopus 로고
    • Does erythropoietin promote tumor growth?
    • Yoon D., Agarwal N., and Prchal J.T. Does erythropoietin promote tumor growth?. Clin Cancer Res 14 (2008) 1920
    • (2008) Clin Cancer Res , vol.14 , pp. 1920
    • Yoon, D.1    Agarwal, N.2    Prchal, J.T.3
  • 18
    • 35148857257 scopus 로고    scopus 로고
    • Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression
    • Hardee M.E., Cao Y., Fu P., Jiang X., Zhao Y., Rabbani Z.N., et al. Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. PLoS ONE 2 (2007) e549
    • (2007) PLoS ONE , vol.2
    • Hardee, M.E.1    Cao, Y.2    Fu, P.3    Jiang, X.4    Zhao, Y.5    Rabbani, Z.N.6
  • 19
    • 40449087690 scopus 로고    scopus 로고
    • The non-haematopoietic biological effects of erythropoietin
    • Arcasoy M.O. The non-haematopoietic biological effects of erythropoietin. Br J Haematol 141 (2008) 14-31
    • (2008) Br J Haematol , vol.141 , pp. 14-31
    • Arcasoy, M.O.1
  • 20
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang G.L., Jiang B.H., Rue E.A., and Semenza G.L. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 92 (1995) 5510-5514
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 21
    • 18744373593 scopus 로고    scopus 로고
    • Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
    • Ang S.O., Chen H., Hirota K., Gordeuk V.R., Jelinek J., Guan Y., et al. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nature Genet 32 (2002) 614-621
    • (2002) Nature Genet , vol.32 , pp. 614-621
    • Ang, S.O.1    Chen, H.2    Hirota, K.3    Gordeuk, V.R.4    Jelinek, J.5    Guan, Y.6
  • 22
    • 0035313697 scopus 로고    scopus 로고
    • HIF-1 and mechanisms of hypoxia sensing
    • Semenza G. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13 (2001) 167-171
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 167-171
    • Semenza, G.1
  • 23
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3    Clifford, S.C.4    Vaux, E.C.5    Cockman, M.E.6
  • 26
    • 2342631195 scopus 로고    scopus 로고
    • Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
    • Gordeuk V., Sergueeva A.I., Miasnikova G.Y., Okhotin D., Voloshin Y., Choyke P.L., et al. Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood 103 (2004) 3924-3932
    • (2004) Blood , vol.103 , pp. 3924-3932
    • Gordeuk, V.1    Sergueeva, A.I.2    Miasnikova, G.Y.3    Okhotin, D.4    Voloshin, Y.5    Choyke, P.L.6
  • 27
    • 0033607291 scopus 로고    scopus 로고
    • Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
    • Iwai K., Yamanaka K., Kamura T., Minato N., Conaway R.C., Conaway J.W., et al. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. Proc Natl Acad Sci U S A 96 (1999) 12436-12441
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12436-12441
    • Iwai, K.1    Yamanaka, K.2    Kamura, T.3    Minato, N.4    Conaway, R.C.5    Conaway, J.W.6
  • 28
    • 33745138232 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia-inducible factor 1
    • Hirota K., and Semenza G.L. Regulation of angiogenesis by hypoxia-inducible factor 1. Crit Rev Oncol Hematol 59 (2006) 15-26
    • (2006) Crit Rev Oncol Hematol , vol.59 , pp. 15-26
    • Hirota, K.1    Semenza, G.L.2
  • 30
    • 33748714735 scopus 로고    scopus 로고
    • The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
    • Chavez J.C., Baranova O., Lin J., and Pichiule P. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J Neurosci 26 (2006) 9471-9481
    • (2006) J Neurosci , vol.26 , pp. 9471-9481
    • Chavez, J.C.1    Baranova, O.2    Lin, J.3    Pichiule, P.4
  • 31
    • 34147124264 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
    • Rankin E.B., Biju M.P., Liu Q., Unger T.L., Rha J., Johnson R.S., et al. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J Clin Invest 117 (2007) 1068-1077
    • (2007) J Clin Invest , vol.117 , pp. 1068-1077
    • Rankin, E.B.1    Biju, M.P.2    Liu, Q.3    Unger, T.L.4    Rha, J.5    Johnson, R.S.6
  • 32
    • 34247628002 scopus 로고    scopus 로고
    • Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency
    • Sanchez M., Galy B., Muckenthaler M.U., and Hentze M.W. Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency. Nat Struct Mol Biol 14 (2007) 420-426
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 420-426
    • Sanchez, M.1    Galy, B.2    Muckenthaler, M.U.3    Hentze, M.W.4
  • 34
    • 35348904953 scopus 로고    scopus 로고
    • RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia
    • Carbia-Nagashima A., Gerez J., Perez-Castro C., Paez-Pereda M., Silberstein S., Stalla G.K., et al. RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell 131 (2007) 309-323
    • (2007) Cell , vol.131 , pp. 309-323
    • Carbia-Nagashima, A.1    Gerez, J.2    Perez-Castro, C.3    Paez-Pereda, M.4    Silberstein, S.5    Stalla, G.K.6
  • 35
    • 37549028456 scopus 로고    scopus 로고
    • Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization
    • Liu Y.V., Hubbi M.E., Pan F., McDonald K.R., Mansharamani M., Cole R.N., et al. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J Biol Chem 282 (2007) 37064-37073
    • (2007) J Biol Chem , vol.282 , pp. 37064-37073
    • Liu, Y.V.1    Hubbi, M.E.2    Pan, F.3    McDonald, K.R.4    Mansharamani, M.5    Cole, R.N.6
  • 36
    • 0035895071 scopus 로고    scopus 로고
    • Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin
    • Skibeli V., Nissen-Lie G., and Torjesen P. Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin. Blood 98 (2001) 3626-3634
    • (2001) Blood , vol.98 , pp. 3626-3634
    • Skibeli, V.1    Nissen-Lie, G.2    Torjesen, P.3
  • 37
    • 0016175381 scopus 로고
    • On the mechanism of erythropoietin-induced differentiation. 13. The role of sialic acid in erythropoietin action
    • Goldwasser E., Kung C.K., and Eliason J. On the mechanism of erythropoietin-induced differentiation. 13. The role of sialic acid in erythropoietin action. J Biol Chem 249 (1974) 4202-4206
    • (1974) J Biol Chem , vol.249 , pp. 4202-4206
    • Goldwasser, E.1    Kung, C.K.2    Eliason, J.3
  • 38
    • 0037384789 scopus 로고    scopus 로고
    • Darbepoetin alfa has a longer circulating half-life and greater in vivo potency than recombinant human erythropoietin
    • Egrie J.C., Dwyer E., Browne J.K., Hitz A., and Lykos M.A. Darbepoetin alfa has a longer circulating half-life and greater in vivo potency than recombinant human erythropoietin. Experimental Hematol 31 (2003) 290-299
    • (2003) Experimental Hematol , vol.31 , pp. 290-299
    • Egrie, J.C.1    Dwyer, E.2    Browne, J.K.3    Hitz, A.4    Lykos, M.A.5
  • 39
    • 34447095903 scopus 로고    scopus 로고
    • Risks and benefits of erythropoiesis-stimulating agents in cancer management
    • Beutel G., and Ganser A. Risks and benefits of erythropoiesis-stimulating agents in cancer management. Semin Hematol 44 (2007) 157-165
    • (2007) Semin Hematol , vol.44 , pp. 157-165
    • Beutel, G.1    Ganser, A.2
  • 40
    • 52049083103 scopus 로고    scopus 로고
    • FDA. USFaDA Accessed April 5, 2008
    • FDA, and USFaDA. http://www.fda.gov/bbs/topics/NEWS/2007/ NEW01740.html Accessed April 5, 2008
  • 41
    • 52049127124 scopus 로고    scopus 로고
    • FDA. USFaDA Drugs and Therapeutic Biological Products (CDER). Accessed April 6, 2008
    • FDA, and USFaDA. http://www.fda.gov/medwatch/safety/2007/safety07.htm#ESA Drugs and Therapeutic Biological Products (CDER). Accessed April 6, 2008
  • 45
    • 33847386390 scopus 로고    scopus 로고
    • Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients
    • Kwan J.T., and Pratt R.D. Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in predialysis chronic kidney disease patients. Curr Med Res Opin 23 (2007) 307-311
    • (2007) Curr Med Res Opin , vol.23 , pp. 307-311
    • Kwan, J.T.1    Pratt, R.D.2
  • 46
    • 34447273146 scopus 로고    scopus 로고
    • The first human cell line-derived erythropoietin, epoetin-delta (Dynepo), in the management of anemia in patients with chronic kidney disease
    • Martin K.J. The first human cell line-derived erythropoietin, epoetin-delta (Dynepo), in the management of anemia in patients with chronic kidney disease. Clin Nephrol 68 (2007) 26-31
    • (2007) Clin Nephrol , vol.68 , pp. 26-31
    • Martin, K.J.1
  • 47
    • 33644875091 scopus 로고    scopus 로고
    • CERA (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia
    • Macdougall I.C. CERA (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia. Curr Hematol Rep 4 (2005) 436-440
    • (2005) Curr Hematol Rep , vol.4 , pp. 436-440
    • Macdougall, I.C.1
  • 48
    • 35448969355 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of methoxy polyethylene glycol-epoetin beta are unaffected by the site of subcutaneous administration
    • Fishbane S., Pannier A., Liogier X., Jordan P., Dougherty F.C., and Reigner B. Pharmacokinetic and pharmacodynamic properties of methoxy polyethylene glycol-epoetin beta are unaffected by the site of subcutaneous administration. J Clin Pharmacol 47 (2007) 1390-1397
    • (2007) J Clin Pharmacol , vol.47 , pp. 1390-1397
    • Fishbane, S.1    Pannier, A.2    Liogier, X.3    Jordan, P.4    Dougherty, F.C.5    Reigner, B.6
  • 49
    • 33947585511 scopus 로고    scopus 로고
    • Phase II study of two dose schedules of C.E.R.A. (continuous erythropoietin receptor activator) in anemic patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy
    • Hirsh V., Glaspy J., Mainwaring P., Manegold C., Ramlau R., and Eid J.E. Phase II study of two dose schedules of C.E.R.A. (continuous erythropoietin receptor activator) in anemic patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy. Trials 8 (2007) 8
    • (2007) Trials , vol.8 , pp. 8
    • Hirsh, V.1    Glaspy, J.2    Mainwaring, P.3    Manegold, C.4    Ramlau, R.5    Eid, J.E.6
  • 50
    • 34548207889 scopus 로고    scopus 로고
    • Once-monthly subcutaneous C.E.R.A. maintains stable hemoglobin control in patients with chronic kidney disease on dialysis and converted directly from epoetin one to three times weekly
    • Sulowicz W., Locatelli F., Ryckelynck J.P., Balla J., Csiky B., Harris K., et al. Once-monthly subcutaneous C.E.R.A. maintains stable hemoglobin control in patients with chronic kidney disease on dialysis and converted directly from epoetin one to three times weekly. Clin J Am Soc Nephrol 2 (2007) 637-646
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 637-646
    • Sulowicz, W.1    Locatelli, F.2    Ryckelynck, J.P.3    Balla, J.4    Csiky, B.5    Harris, K.6
  • 51
    • 35348839061 scopus 로고    scopus 로고
    • Intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: A randomised non-inferiority trial (MAXIMA)
    • Levin N.W., Fishbane S., Canedo F.V., Zeig S., Nassar G.M., Moran J.E., et al. Intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: A randomised non-inferiority trial (MAXIMA). Lancet 370 (2007) 1415-1421
    • (2007) Lancet , vol.370 , pp. 1415-1421
    • Levin, N.W.1    Fishbane, S.2    Canedo, F.V.3    Zeig, S.4    Nassar, G.M.5    Moran, J.E.6
  • 52
    • 34548829081 scopus 로고    scopus 로고
    • HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques
    • Hsieh M.M., Linde N.S., Wynter A., Metzger M., Wong C., Langsetmo I., et al. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. Blood 110 (2007) 2140-2147
    • (2007) Blood , vol.110 , pp. 2140-2147
    • Hsieh, M.M.1    Linde, N.S.2    Wynter, A.3    Metzger, M.4    Wong, C.5    Langsetmo, I.6
  • 53
    • 50649115663 scopus 로고    scopus 로고
    • The prolyl hydroxylase inhibitor FG-2216 stimulates EPO production in nephric and anephric dialysis patients-Evidence for an underutilized production capacity in liver and kidneys
    • San Francisco, CA, November 2-5, (abstr SA-PO784)
    • Bernhardt W., Wiesener M.S., Schmieder R.E., Gunzler V., Eckardt K.U., et al. The prolyl hydroxylase inhibitor FG-2216 stimulates EPO production in nephric and anephric dialysis patients-Evidence for an underutilized production capacity in liver and kidneys. American Society of Nephrology Renal Week (2007) San Francisco, CA, November 2-5, (abstr SA-PO784)
    • (2007) American Society of Nephrology Renal Week
    • Bernhardt, W.1    Wiesener, M.S.2    Schmieder, R.E.3    Gunzler, V.4    Eckardt, K.U.5
  • 54
    • 52049113096 scopus 로고    scopus 로고
    • Results from a randomized, single-blind, placebo-controlled trial of FG-4592, a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia
    • San Francisco, CA, November 2-5, (abstr SU-PO806)
    • Frohna P., Milwee S., Pinkett J., Lee T., Moore-Perry K., Chou J., et al. Results from a randomized, single-blind, placebo-controlled trial of FG-4592, a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia. American Society of Nephrology Renal Week (2007) San Francisco, CA, November 2-5, (abstr SU-PO806)
    • (2007) American Society of Nephrology Renal Week
    • Frohna, P.1    Milwee, S.2    Pinkett, J.3    Lee, T.4    Moore-Perry, K.5    Chou, J.6
  • 55
    • 0032539954 scopus 로고    scopus 로고
    • Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1
    • Johnson D.L., Farrell F.X., Barbone F.P., McMahon F.J., Tullai J., Hoey K., et al. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1. Biochemistry 37 (1998) 3699-3710
    • (1998) Biochemistry , vol.37 , pp. 3699-3710
    • Johnson, D.L.1    Farrell, F.X.2    Barbone, F.P.3    McMahon, F.J.4    Tullai, J.5    Hoey, K.6
  • 56
    • 38749115086 scopus 로고    scopus 로고
    • Novel erythropoiesis-stimulating agents: A new era in anemia management
    • Macdougall I.C. Novel erythropoiesis-stimulating agents: A new era in anemia management. Clin J Am Soc Nephrol 3 (2008) 200-207
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 200-207
    • Macdougall, I.C.1
  • 57
    • 33748690610 scopus 로고    scopus 로고
    • Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia
    • Fan Q., Leuther K.K., Holmes C.P., Fong K.L., Zhang J., Velkovska S., et al. Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia. Exp Hematol 34 (2006) 1303-1311
    • (2006) Exp Hematol , vol.34 , pp. 1303-1311
    • Fan, Q.1    Leuther, K.K.2    Holmes, C.P.3    Fong, K.L.4    Zhang, J.5    Velkovska, S.6
  • 58
    • 33748679131 scopus 로고    scopus 로고
    • Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers
    • Stead R.B., Lambert J., Wessels D., Iwashita J.S., Leuther K.K., Woodburn K.W., et al. Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers. Blood 108 (2006) 1830-1834
    • (2006) Blood , vol.108 , pp. 1830-1834
    • Stead, R.B.1    Lambert, J.2    Wessels, D.3    Iwashita, J.S.4    Leuther, K.K.5    Woodburn, K.W.6
  • 59
    • 52049085631 scopus 로고    scopus 로고
    • Hematide, a synthetic peptide-based erythropoiesis stimulating agent, achieves correction of anemia and maintains hemoglobin in patients with chronic kidney disease not on dialysis
    • November 14-19, (abstr F-FC079)
    • Macdougall I., Tucker B., Yaqoob M., Mikhail A., Nowicki M., MacPhee I., et al. Hematide, a synthetic peptide-based erythropoiesis stimulating agent, achieves correction of anemia and maintains hemoglobin in patients with chronic kidney disease not on dialysis. Annual meeting of the American Society of Nephrology, San Diego, CA (2006) November 14-19, (abstr F-FC079)
    • (2006) Annual meeting of the American Society of Nephrology, San Diego, CA
    • Macdougall, I.1    Tucker, B.2    Yaqoob, M.3    Mikhail, A.4    Nowicki, M.5    MacPhee, I.6
  • 60
    • 77749337345 scopus 로고    scopus 로고
    • Hematide, a synthetic peptide-based erythropoiesis stimulating agent, maintains hemoglobin in hemodialysis patients previously treated epoetin alfa
    • April 10-14, (abstr 99)
    • Besarab A., Zeig S., Geronemus R., Pergola P., Whittier F., Zabaneh R., et al. Hematide, a synthetic peptide-based erythropoiesis stimulating agent, maintains hemoglobin in hemodialysis patients previously treated epoetin alfa. National Kidney Foundation Spring Clinical Meeting, Orlando, FL (2007) April 10-14, (abstr 99)
    • (2007) National Kidney Foundation Spring Clinical Meeting, Orlando, FL
    • Besarab, A.1    Zeig, S.2    Geronemus, R.3    Pergola, P.4    Whittier, F.5    Zabaneh, R.6
  • 61
    • 52049116764 scopus 로고    scopus 로고
    • Correction of anemia with Hematide, a synthetic peptide-based erythropoiesis stimulating agent (ESA), in oncology patients receiving chemotherapy
    • (abstr 3666)
    • Pickering L., Cwiertka K., Jassem J., Petera J., Pettengell R., Ramlau R., et al. Correction of anemia with Hematide, a synthetic peptide-based erythropoiesis stimulating agent (ESA), in oncology patients receiving chemotherapy. Blood 110 (2007) (abstr 3666)
    • (2007) Blood , vol.110
    • Pickering, L.1    Cwiertka, K.2    Jassem, J.3    Petera, J.4    Pettengell, R.5    Ramlau, R.6
  • 62
    • 34447636387 scopus 로고    scopus 로고
    • Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model
    • Woodburn K.W., Fan Q., Winslow S., Chen M.J., Mortensen R.B., Casadevall N., et al. Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model. Exp Hematol 35 (2007) 1201-1208
    • (2007) Exp Hematol , vol.35 , pp. 1201-1208
    • Woodburn, K.W.1    Fan, Q.2    Winslow, S.3    Chen, M.J.4    Mortensen, R.B.5    Casadevall, N.6
  • 63
    • 39649085543 scopus 로고    scopus 로고
    • CNTO 530: Molecular pharmacology in human UT-7(EPO) cells and pharmacokinetics and pharmacodynamics in mice
    • Bugelski P.J., Capocasale R.J., Makropoulos D., Marshall D., Fisher P.W., Lu J., et al. CNTO 530: Molecular pharmacology in human UT-7(EPO) cells and pharmacokinetics and pharmacodynamics in mice. J Biotechnol 134 (2008) 171-180
    • (2008) J Biotechnol , vol.134 , pp. 171-180
    • Bugelski, P.J.1    Capocasale, R.J.2    Makropoulos, D.3    Marshall, D.4    Fisher, P.W.5    Lu, J.6
  • 64
    • 10244260353 scopus 로고    scopus 로고
    • Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease
    • Nakano Y., Imagawa S., Matsumoto K., Stockmann C., Obara N., Suzuki N., et al. Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease. Blood 104 (2004) 4300-4307
    • (2004) Blood , vol.104 , pp. 4300-4307
    • Nakano, Y.1    Imagawa, S.2    Matsumoto, K.3    Stockmann, C.4    Obara, N.5    Suzuki, N.6
  • 66
    • 0035353166 scopus 로고    scopus 로고
    • Pharmacologically regulated cell therapy
    • Neff T., and Blau C.A. Pharmacologically regulated cell therapy. Blood 97 (2001) 2535-2540
    • (2001) Blood , vol.97 , pp. 2535-2540
    • Neff, T.1    Blau, C.A.2
  • 68
    • 0037105534 scopus 로고    scopus 로고
    • Pharmacologically regulated in vivo selection in a large animal
    • Neff T., Horn P.A., Valli V.E., Gown A.M., Wardwell S., Wood B.L., et al. Pharmacologically regulated in vivo selection in a large animal. Blood 100 (2002) 2026-2031
    • (2002) Blood , vol.100 , pp. 2026-2031
    • Neff, T.1    Horn, P.A.2    Valli, V.E.3    Gown, A.M.4    Wardwell, S.5    Wood, B.L.6
  • 69
    • 33745502225 scopus 로고    scopus 로고
    • Anatomical compartments modify the response of human hematopoietic cells to a mitogenic signal
    • Nagasawa Y., Wood B.L., Wang L., Lintmaer I., Guo W., Papayannopoulou T., et al. Anatomical compartments modify the response of human hematopoietic cells to a mitogenic signal. Stem Cells 24 (2006) 908-917
    • (2006) Stem Cells , vol.24 , pp. 908-917
    • Nagasawa, Y.1    Wood, B.L.2    Wang, L.3    Lintmaer, I.4    Guo, W.5    Papayannopoulou, T.6
  • 70
    • 34548501737 scopus 로고    scopus 로고
    • Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation
    • Chen Z.Y., Asavaritikrai P., Prchal J.T., and Noguchi C.T. Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation. J BiolChem 282 (2007) 25875-25883
    • (2007) J BiolChem , vol.282 , pp. 25875-25883
    • Chen, Z.Y.1    Asavaritikrai, P.2    Prchal, J.T.3    Noguchi, C.T.4
  • 71
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    • Brines M., Grasso G., Fiordaliso F., Sfacteria A., Ghezzi P., Fratelli M., et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A 101 (2004) 14907-14912
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14907-14912
    • Brines, M.1    Grasso, G.2    Fiordaliso, F.3    Sfacteria, A.4    Ghezzi, P.5    Fratelli, M.6
  • 72
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M., and Lipton S.A. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412 (2001) 641-647
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 73
    • 1842610133 scopus 로고    scopus 로고
    • Erythropoietin and the nervous system
    • Genc S., Koroglu T.F., and Genc K. Erythropoietin and the nervous system. Brain Res 1000 (2004) 19-31
    • (2004) Brain Res , vol.1000 , pp. 19-31
    • Genc, S.1    Koroglu, T.F.2    Genc, K.3
  • 74
    • 33644791801 scopus 로고    scopus 로고
    • Erythropoietin reduces perihematomal inflammation and cell death with eNOS and STAT3 activations in experimental intracerebral hemorrhage
    • Lee S.T., Chu K., Sinn D.I., Jung K.H., Kim E.H., Kim S.J., et al. Erythropoietin reduces perihematomal inflammation and cell death with eNOS and STAT3 activations in experimental intracerebral hemorrhage. J Neurochem 96 (2006) 1728-1739
    • (2006) J Neurochem , vol.96 , pp. 1728-1739
    • Lee, S.T.1    Chu, K.2    Sinn, D.I.3    Jung, K.H.4    Kim, E.H.5    Kim, S.J.6
  • 76
    • 23944523376 scopus 로고    scopus 로고
    • Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy
    • Watanabe D., Suzuma K., Matsui S., Kurimoto M., Kiryu J., Kita M., et al. Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. N Engl J Med 353 (2005) 782-792
    • (2005) N Engl J Med , vol.353 , pp. 782-792
    • Watanabe, D.1    Suzuma, K.2    Matsui, S.3    Kurimoto, M.4    Kiryu, J.5    Kita, M.6
  • 78
    • 34848841517 scopus 로고    scopus 로고
    • Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis
    • Ehrenreich H., Fischer B., Norra C., Schellenberger F., Stender N., Stiefel M., et al. Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain 130 (2007) 2577-2588
    • (2007) Brain , vol.130 , pp. 2577-2588
    • Ehrenreich, H.1    Fischer, B.2    Norra, C.3    Schellenberger, F.4    Stender, N.5    Stiefel, M.6
  • 79
    • 34547902867 scopus 로고    scopus 로고
    • Erythropoietin in cancer: Presumption of innocence?
    • Blau C.A. Erythropoietin in cancer: Presumption of innocence?. Stem Cells 25 (2007) 2094-2097
    • (2007) Stem Cells , vol.25 , pp. 2094-2097
    • Blau, C.A.1
  • 80
    • 33344461329 scopus 로고    scopus 로고
    • Anti-Epo receptor antibodies do not predict Epo receptor expression
    • Elliott S., Busse L., Bass M.B., Lu H., Sarosi I., Sinclair A.M., et al. Anti-Epo receptor antibodies do not predict Epo receptor expression. Blood 107 (2006) 1892-1895
    • (2006) Blood , vol.107 , pp. 1892-1895
    • Elliott, S.1    Busse, L.2    Bass, M.B.3    Lu, H.4    Sarosi, I.5    Sinclair, A.M.6
  • 81
    • 34249108436 scopus 로고    scopus 로고
    • The diverse functions of Lipocalin: A recently-recognized mediator of transferrin independent iron transport, innate immunity, and cancer signaling
    • Necas E., and Prchal J.T. The diverse functions of Lipocalin: A recently-recognized mediator of transferrin independent iron transport, innate immunity, and cancer signaling. Hematologist 3 (2006) 3
    • (2006) Hematologist , vol.3 , pp. 3
    • Necas, E.1    Prchal, J.T.2
  • 82
    • 33749515083 scopus 로고    scopus 로고
    • A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
    • Whitnall M., Howard J., Ponka P., and Richardson D.R. A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. Proc Natl Acad Scie U S A 103 (2006) 14901-14906
    • (2006) Proc Natl Acad Scie U S A , vol.103 , pp. 14901-14906
    • Whitnall, M.1    Howard, J.2    Ponka, P.3    Richardson, D.R.4
  • 83
    • 40349103260 scopus 로고    scopus 로고
    • Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia
    • Bennett C.L., Silver S.M., Djulbegovic B., Samaras A.T., Blau C.A., Gleason K.J., et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA 299 (2008) 914-924
    • (2008) JAMA , vol.299 , pp. 914-924
    • Bennett, C.L.1    Silver, S.M.2    Djulbegovic, B.3    Samaras, A.T.4    Blau, C.A.5    Gleason, K.J.6
  • 84
    • 38549171251 scopus 로고    scopus 로고
    • Does epoetin alfa improve health-related quality of life in chronically ill patients with anemia?. Summary of trials of cancer, HIV/AIDS, and chronic kidney disease
    • Kimel M., Leidy N.K., Mannix S., and Dixon J. Does epoetin alfa improve health-related quality of life in chronically ill patients with anemia?. Summary of trials of cancer, HIV/AIDS, and chronic kidney disease. Value Health 11 (2008) 57-75
    • (2008) Value Health , vol.11 , pp. 57-75
    • Kimel, M.1    Leidy, N.K.2    Mannix, S.3    Dixon, J.4
  • 85
    • 0033029430 scopus 로고    scopus 로고
    • Human, rat, and mouse kidney cells express functional erythropoietin receptors
    • Westenfelder C., Biddle D.L., and Baranowski R.L. Human, rat, and mouse kidney cells express functional erythropoietin receptors. Kidney Int 55 (1999) 808-820
    • (1999) Kidney Int , vol.55 , pp. 808-820
    • Westenfelder, C.1    Biddle, D.L.2    Baranowski, R.L.3
  • 86
    • 34447093331 scopus 로고    scopus 로고
    • Erythropoietin and treatment of non-anemic conditions-Cardiovascular protection
    • Fliser D., and Haller H. Erythropoietin and treatment of non-anemic conditions-Cardiovascular protection. Semin Hematol 44 (2007) 212-217
    • (2007) Semin Hematol , vol.44 , pp. 212-217
    • Fliser, D.1    Haller, H.2
  • 87
    • 4344626952 scopus 로고    scopus 로고
    • Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure
    • Bahlmann F.H., Song R., Boehm S.M., Mengel M., von Wasielewski R., Lindschau C., et al. Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure. Circulation 110 (2004) 1006-1012
    • (2004) Circulation , vol.110 , pp. 1006-1012
    • Bahlmann, F.H.1    Song, R.2    Boehm, S.M.3    Mengel, M.4    von Wasielewski, R.5    Lindschau, C.6
  • 89
    • 34848832453 scopus 로고    scopus 로고
    • Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization
    • Westenbrink B.D., Lipsic E., van der Meer P., van der Harst P., Oeseburg H., Du Marchie Sarvaas G.J., et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J 28 (2007) 2018-2027
    • (2007) Eur Heart J , vol.28 , pp. 2018-2027
    • Westenbrink, B.D.1    Lipsic, E.2    van der Meer, P.3    van der Harst, P.4    Oeseburg, H.5    Du Marchie Sarvaas, G.J.6
  • 90
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A., Bolton W.K., Browne J.K., Egrie J.C., Nissenson A.R., Okamoto D.M., et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med Aug 339 (1998) 584-590
    • (1998) N Engl J Med Aug , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3    Egrie, J.C.4    Nissenson, A.R.5    Okamoto, D.M.6
  • 91
    • 41049115024 scopus 로고    scopus 로고
    • Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia
    • Ghali J.K., Anand I.S., Abraham W.T., Fonarow G.C., Greenberg B., Krum H., et al. Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia. Circulation 117 (2008) 526-535
    • (2008) Circulation , vol.117 , pp. 526-535
    • Ghali, J.K.1    Anand, I.S.2    Abraham, W.T.3    Fonarow, G.C.4    Greenberg, B.5    Krum, H.6
  • 93
    • 2342631195 scopus 로고    scopus 로고
    • Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
    • Gordeuk V.R., Sergueeva A.I., Miasnikova G.Y., Okhotin D., Voloshin Y., Choyke P.L., et al. Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood 103 (2004) 3924-3932
    • (2004) Blood , vol.103 , pp. 3924-3932
    • Gordeuk, V.R.1    Sergueeva, A.I.2    Miasnikova, G.Y.3    Okhotin, D.4    Voloshin, Y.5    Choyke, P.L.6
  • 94
    • 33646905411 scopus 로고    scopus 로고
    • Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients
    • Bohlius J., Wilson J., Seidenfeld J., Piper M., Schwarzer G., Sandercock J., et al. Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. J Natl Cancer Inst 98 (2006) 708-714
    • (2006) J Natl Cancer Inst , vol.98 , pp. 708-714
    • Bohlius, J.1    Wilson, J.2    Seidenfeld, J.3    Piper, M.4    Schwarzer, G.5    Sandercock, J.6
  • 96
    • 0037065340 scopus 로고    scopus 로고
    • Efficacy of recombinant human erythropoietin in critically ill patients: A randomized controlled trial
    • Corwin H.L., Gettinger A., Pearl R.G., Fink M.P., Levy M.M., Shapiro M.J., et al. Efficacy of recombinant human erythropoietin in critically ill patients: A randomized controlled trial. JAMA 288 (2002) 2827-2835
    • (2002) JAMA , vol.288 , pp. 2827-2835
    • Corwin, H.L.1    Gettinger, A.2    Pearl, R.G.3    Fink, M.P.4    Levy, M.M.5    Shapiro, M.J.6
  • 98
    • 4944261763 scopus 로고    scopus 로고
    • Prevalence of anemia in persons 65 years and older in the United States: Evidence for a high rate of unexplained anemia
    • Guralnik J.M., Eisenstaedt R.S., Ferrucci L., Klein H.G., and Woodman R.C. Prevalence of anemia in persons 65 years and older in the United States: Evidence for a high rate of unexplained anemia. Blood 104 (2004) 2263-2268
    • (2004) Blood , vol.104 , pp. 2263-2268
    • Guralnik, J.M.1    Eisenstaedt, R.S.2    Ferrucci, L.3    Klein, H.G.4    Woodman, R.C.5
  • 100
    • 0033744783 scopus 로고    scopus 로고
    • Blood haemoglobin declines in the elderly: implications for reference intervals from age 70 to 88
    • Nilsson-Ehle H., Jagenburg R., Landahl S., and Svanborg A. Blood haemoglobin declines in the elderly: implications for reference intervals from age 70 to 88. Eur J Haematol 65 (2000) 297-305
    • (2000) Eur J Haematol , vol.65 , pp. 297-305
    • Nilsson-Ehle, H.1    Jagenburg, R.2    Landahl, S.3    Svanborg, A.4
  • 101
    • 2342488634 scopus 로고    scopus 로고
    • Anemia is associated with disability and decreased physical performance and muscle strength in the elderly
    • Penninx B.W., Pahor M., Cesari M., Corsi A.M., Woodman R.C., Bandinelli S., et al. Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc 52 (2004) 719-724
    • (2004) J Am Geriatr Soc , vol.52 , pp. 719-724
    • Penninx, B.W.1    Pahor, M.2    Cesari, M.3    Corsi, A.M.4    Woodman, R.C.5    Bandinelli, S.6
  • 103
    • 44849137629 scopus 로고    scopus 로고
    • Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study
    • Lucca U., Tettamanti M., Mosconi P., Apolone G., Gandini F., Nobili A., et al. Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study. PLoS ONE 3 (2008) e1920
    • (2008) PLoS ONE , vol.3
    • Lucca, U.1    Tettamanti, M.2    Mosconi, P.3    Apolone, G.4    Gandini, F.5    Nobili, A.6
  • 104
    • 33645222620 scopus 로고    scopus 로고
    • Impact of anemia on mortality, cognition, and function in community-dwelling elderly
    • Denny S.D., Kuchibhatla M.N., and Cohen H.J. Impact of anemia on mortality, cognition, and function in community-dwelling elderly. Am J Med 119 (2006) 327-334
    • (2006) Am J Med , vol.119 , pp. 327-334
    • Denny, S.D.1    Kuchibhatla, M.N.2    Cohen, H.J.3
  • 105
    • 34848904495 scopus 로고    scopus 로고
    • Types of anemia and mortality among older disabled women living in the community: The Women's Health and Aging Study I
    • Semba R.D., Ricks M.O., Ferrucci L., Xue Q.L., Chaves P., Fried L.P., et al. Types of anemia and mortality among older disabled women living in the community: The Women's Health and Aging Study I. Aging Clin Exp Res 19 (2007) 259-264
    • (2007) Aging Clin Exp Res , vol.19 , pp. 259-264
    • Semba, R.D.1    Ricks, M.O.2    Ferrucci, L.3    Xue, Q.L.4    Chaves, P.5    Fried, L.P.6
  • 107
    • 30944445958 scopus 로고    scopus 로고
    • Economic burden of patients with anemia in selected diseases
    • Ershler W.B., Chen K., Reyes E.B., and Dubois R. Economic burden of patients with anemia in selected diseases. Value Health 8 (2005) 629-638
    • (2005) Value Health , vol.8 , pp. 629-638
    • Ershler, W.B.1    Chen, K.2    Reyes, E.B.3    Dubois, R.4


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