Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening

Journal of Medicinal Chemistry

Volumn 51, Issue 17, 2008, Pages 5297-5303

  Taylor, Christina M ^a   Barda, Yaniv ^a,c   Kisselev, Oleg G ^b   Marshall, Garland R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; NSC 114945; NSC 128437; NSC 159628; NSC 1614; NSC 35347; NSC 35350; NSC 382025; NSC 4060; NSC 521777; NSC 601364; NSC 81395; NSC 82878; NSC 88135; NSC 88915; NSC 93241; NSC 95090; RECEPTOR BLOCKING AGENT; RHODOPSIN; TRANSDUCIN; UNCLASSIFIED DRUG;

ARTICLE; MOLECULAR DOCKING; MOLECULAR MODEL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ANIMALS; COMPUTER SIMULATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; SIGNAL TRANSDUCTION; TRANSDUCIN;

EID: 51849091933     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800326q     Document Type: Article

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