Mathematical modeling identified c-FLIP as an apoptotic switch in death receptor induced apoptosis

Apoptosis

Volumn 13, Issue 10, 2008, Pages 1198-1204

  Han, Lihui ^a   Zhao, Yishu ^b   Jia, Xiaoqing ^c  

^a SHANDONG UNIVERSITY   (China)

^b STATE GRID SHANDONG ELECTRIC POWER RESEARCH INSTITUTE   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis probability; Apoptotic switch; Bistability; c FLIP; Mathematical modeling; Robustness

Indexed keywords

CASPASE 3; CASPASE 8; DEATH RECEPTOR; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

APOPTOSIS; ARTICLE; CELL SURVIVAL; ENZYME ACTIVATION; MATHEMATICAL MODEL; NEOPLASM; PRIORITY JOURNAL; PROTEIN FUNCTION; SIMULATION; STIMULUS RESPONSE;

ANIMALS; APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 3; CASPASE 8; CELL SURVIVAL; ENZYME ACTIVATION; MODELS, BIOLOGICAL; NF-KAPPA B; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION;

EID: 51749096877     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0252-3     Document Type: Article

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