Non-linear pharmacodynamics in the transfection efficiency of a non-viral gene delivery system

International Journal of Pharmaceutics

Volumn 363, Issue 1-2, 2008, Pages 192-198

  Moriguchi, Rumiko ^a,b   Kogure, Kentaro ^b,c   Harashima, Hideyoshi ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Intracellular pharmacokinetics; Intranuclear disposition; Non viral gene delivery systems; Nonlinearity; Pharmacodynamics

Indexed keywords

LIPID; LIPOFECTAMINE; LIPOPLEX; PLASMID DNA;

ANIMAL CELL; ARTICLE; CELL TRANSPORT; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; GENETIC TRANSFECTION; NONHUMAN; NONLINEAR SYSTEM; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHARMACODYNAMICS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; DNA; GENE EXPRESSION; KINETICS; LIPIDS; LIPOSOMES; MICE; MODELS, GENETIC; NIH 3T3 CELLS; NONLINEAR DYNAMICS; PARTICLE SIZE; TRANSFECTION;

EID: 51649120517     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.07.020     Document Type: Article

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