-
1
-
-
27544516024
-
Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases
-
Johnson, E. F., and Stout, C. D. (2005) Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases. Biochem. Biophys. Res. Commun. 338, 331-336.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.338
, pp. 331-336
-
-
Johnson, E.F.1
Stout, C.D.2
-
2
-
-
33846373967
-
Structure-function analysis of cytochromes P 450 2B
-
Zhao, Y., and Halpert, J. R. (2007) Structure-function analysis of cytochromes P 450 2B. Biochim. Biophys. Acta 1770, 402-412.
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, pp. 402-412
-
-
Zhao, Y.1
Halpert, J.R.2
-
3
-
-
3042553224
-
Structure of Mammalian Cytochrome P450 2B4 Complexed with 4-(4-Chlorophenyl)imidazole at 1.9-Å Resolution: Insight into the Range of P450 Conformations and the Coordination of Redox Partner Binding
-
Scott, E. E., White, M. A., He, Y. A., Johnson, E. F., Stout, C. D., and Halpert, J. R. (2004) Structure of Mammalian Cytochrome P450 2B4 Complexed with 4-(4-Chlorophenyl)imidazole at 1.9-Å Resolution: Insight into the Range of P450 Conformations and the Coordination of Redox Partner Binding. J. Biol. Chem. 279, 27294-27301.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 27294-27301
-
-
Scott, E.E.1
White, M.A.2
He, Y.A.3
Johnson, E.F.4
Stout, C.D.5
Halpert, J.R.6
-
4
-
-
0035984571
-
Oxidizing Species in the Mechanism of Cytochrome P450
-
Ortiz de Montellano, P. R., and De Voss, J. J. (2002) Oxidizing Species in the Mechanism of Cytochrome P450. Nat. Prod. Rep. 19, 477-493.
-
(2002)
Nat. Prod. Rep
, vol.19
, pp. 477-493
-
-
Ortiz de Montellano, P.R.1
De Voss, J.J.2
-
5
-
-
39749108827
-
Revisiting Heme Mechanisms. A Perspective on the Mechanisms of Nitric Oxide Synthase (NOS), Heme Oxygenase (HO), and Cytochrome P450s (CYP450s)
-
Zhu, Y., and Silverman, R. B. (2008) Revisiting Heme Mechanisms. A Perspective on the Mechanisms of Nitric Oxide Synthase (NOS), Heme Oxygenase (HO), and Cytochrome P450s (CYP450s). Biochemistry 47, 2231-2243.
-
(2008)
Biochemistry
, vol.47
, pp. 2231-2243
-
-
Zhu, Y.1
Silverman, R.B.2
-
6
-
-
0037228374
-
Multiple mechanisms and multiple oxidants in P 450-catalyzed hydroxylations
-
Newcomb, M., Hollenberg, P. F., and Coon, M. J. (2002) Multiple mechanisms and multiple oxidants in P 450-catalyzed hydroxylations. Arch. Biochem. Biophys. 409, 72-79.
-
(2002)
Arch. Biochem. Biophys
, vol.409
, pp. 72-79
-
-
Newcomb, M.1
Hollenberg, P.F.2
Coon, M.J.3
-
7
-
-
13444266016
-
Substrate Modulation of the Properties and Reactivity of the Oxy-Ferrous and Hydroperoxoferric Intermediates of Cytochrome P450cam as Shown by Cryoreduction- EPR/ENDOR Spectroscopy
-
Davydov, R., Perera, R., Jin, S., Yang, T.-C., Bryson, T. A., Sono, M., Dawson, J. H., and Hoffman, B. M. (2005) Substrate Modulation of the Properties and Reactivity of the Oxy-Ferrous and Hydroperoxoferric Intermediates of Cytochrome P450cam as Shown by Cryoreduction- EPR/ENDOR Spectroscopy. J. Am. Chem. Soc. 127, 1403-1413.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 1403-1413
-
-
Davydov, R.1
Perera, R.2
Jin, S.3
Yang, T.-C.4
Bryson, T.A.5
Sono, M.6
Dawson, J.H.7
Hoffman, B.M.8
-
8
-
-
0242585454
-
Epoxidation of Olefins by Hydroperoxo-Ferric Cytochrome P450
-
Jin, S., Makris, T. M., Bryson, T. A., Sligar, S. G., and Dawson, J. H. (2003) Epoxidation of Olefins by Hydroperoxo-Ferric Cytochrome P450. J. Am. Chem. Soc. 125, 3406-3407.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 3406-3407
-
-
Jin, S.1
Makris, T.M.2
Bryson, T.A.3
Sligar, S.G.4
Dawson, J.H.5
-
9
-
-
0035925164
-
Hydroxylation of Camphor by Reduced oxy-Cytochrome P450cam: Mechanistic Implications of EPR and ENDOR of Catalytic Intermediates in Native and Mutant Enzymes
-
Davydov, R., Makris, T. M., Kofman, V., Werst, D. W., Sligar, S. G., and Hoffman, B. M. (2001) Hydroxylation of Camphor by Reduced oxy-Cytochrome P450cam: Mechanistic Implications of EPR and ENDOR of Catalytic Intermediates in Native and Mutant Enzymes. J. Am. Chem. Soc. 123, 1403-1415.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 1403-1415
-
-
Davydov, R.1
Makris, T.M.2
Kofman, V.3
Werst, D.W.4
Sligar, S.G.5
Hoffman, B.M.6
-
10
-
-
9744265664
-
Models and mechanisms of O-O bond activation by cytochrome P450. A critical assessment of the potential role of multiple active intermediates in oxidative catalysis
-
Hlavica, P. (2004) Models and mechanisms of O-O bond activation by cytochrome P450. A critical assessment of the potential role of multiple active intermediates in oxidative catalysis. Eur. J. Biochem. 271, 4335-4360.
-
(2004)
Eur. J. Biochem
, vol.271
, pp. 4335-4360
-
-
Hlavica, P.1
-
11
-
-
0034088779
-
The catalytic pathway of cytochrome P450cam at atomic resolution
-
Schlichting, I., Berendzen, J., Chu, K., Stock, A. M., Maves, S. A., Benson, D. E., Sweet, B. M., Ringe, D., Petsko, G. A., and Sligar, S. G. (2000) The catalytic pathway of cytochrome P450cam at atomic resolution. Science 287, 1615-1622.
-
(2000)
Science
, vol.287
, pp. 1615-1622
-
-
Schlichting, I.1
Berendzen, J.2
Chu, K.3
Stock, A.M.4
Maves, S.A.5
Benson, D.E.6
Sweet, B.M.7
Ringe, D.8
Petsko, G.A.9
Sligar, S.G.10
-
12
-
-
0030004087
-
Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: Switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4
-
Vaz, A. D. N., Pernecky, S. J., Raner, G. M., and Coon, M. J. (1996) Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: Switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4. Proc. Natl. Acad. Sci. U.S.A. 93, 4644-4648.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 4644-4648
-
-
Vaz, A.D.N.1
Pernecky, S.J.2
Raner, G.M.3
Coon, M.J.4
-
13
-
-
0345257913
-
Multiple oxidants and multiple mechanisms in cytochrome P450 catalysis
-
Coon, M. J. (2003) Multiple oxidants and multiple mechanisms in cytochrome P450 catalysis. Biochem. Biophys. Res. Commun. 312, 163-168.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.312
, pp. 163-168
-
-
Coon, M.J.1
-
14
-
-
35648963202
-
Cytochrome b5 Increases the Rate of Product Formation by Cytochrome P450 2B4 and Competes with Cytochrome P450 Reductase for a Binding Site on Cytochrome P450 2B4
-
Zhang, H., Im, S.-C., and Waskell, L. (2007) Cytochrome b5 Increases the Rate of Product Formation by Cytochrome P450 2B4 and Competes with Cytochrome P450 Reductase for a Binding Site on Cytochrome P450 2B4. J. Biol. Chem. 282, 29766-29776.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 29766-29776
-
-
Zhang, H.1
Im, S.-C.2
Waskell, L.3
-
15
-
-
2442667845
-
Conformational Substates of the Oxyheme Centers in α and β Subunits of Hemoglobin as Disclosed by EPR and ENDOR Studies of Cryoreduced Protein
-
Davydov, R., Kofman, V., Nocek, J., Noble, R. W., Hui, H., and Hoffman, B. M. (2004) Conformational Substates of the Oxyheme Centers in α and β Subunits of Hemoglobin as Disclosed by EPR and ENDOR Studies of Cryoreduced Protein. Biochemistry 43, 6330-6338.
-
(2004)
Biochemistry
, vol.43
, pp. 6330-6338
-
-
Davydov, R.1
Kofman, V.2
Nocek, J.3
Noble, R.W.4
Hui, H.5
Hoffman, B.M.6
-
16
-
-
0034710795
-
EPR Spectrometry of Cytochrome P450 2B4: Effects of Mutations and Substrate Binding
-
LeLean, J. E., Moon, N., Dunham, W. R., and Coon, M. J. (2000) EPR Spectrometry of Cytochrome P450 2B4: Effects of Mutations and Substrate Binding. Biochem. Biophys. Res. Commun. 276, 762-766.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.276
, pp. 762-766
-
-
LeLean, J.E.1
Moon, N.2
Dunham, W.R.3
Coon, M.J.4
-
17
-
-
2542520761
-
Theoretical study of the ligand-CYP2B4 complexes: Effect of structure on binding free energies and heme spin state
-
Harris, D. L., Park, J.-Y., Gruenke, L., and Waskell, L. (2004) Theoretical study of the ligand-CYP2B4 complexes: Effect of structure on binding free energies and heme spin state. Proteins: Struct., Funct., Bioinf. 55, 895-914.
-
(2004)
Proteins: Struct., Funct., Bioinf. 55
, pp. 895-914
-
-
Harris, D.L.1
Park, J.-Y.2
Gruenke, L.3
Waskell, L.4
-
18
-
-
0019330820
-
Electron paramagnetic resonance detectable states of cytochrome P-450cam
-
Lipscomb, J. D. (1980) Electron paramagnetic resonance detectable states of cytochrome P-450cam. Biochemistry 19, 3590-3599.
-
(1980)
Biochemistry
, vol.19
, pp. 3590-3599
-
-
Lipscomb, J.D.1
-
19
-
-
0018802561
-
Highly-purified microsomal P-450: The oxyferro intermediate stabilized at low temperature
-
Bonfils, C., Debey, P., and Maurel, P. (1979) Highly-purified microsomal P-450: The oxyferro intermediate stabilized at low temperature. Biochem. Biophys. Res. Commun. 88, 1301-1307.
-
(1979)
Biochem. Biophys. Res. Commun
, vol.88
, pp. 1301-1307
-
-
Bonfils, C.1
Debey, P.2
Maurel, P.3
-
20
-
-
0347064293
-
-
Davydov, R., Satterlee, J. D., Fujii, H., Sauer-Masarwa, A., Busch, D. H., and Hoffman, B. M. (2003) A Superoxo-Ferrous State in a Reduced Oxy-Ferrous Hemoprotein and Model Compounds. J. Am. Chem. Soc. 125, 16340-16346.
-
Davydov, R., Satterlee, J. D., Fujii, H., Sauer-Masarwa, A., Busch, D. H., and Hoffman, B. M. (2003) A Superoxo-Ferrous State in a Reduced Oxy-Ferrous Hemoprotein and Model Compounds. J. Am. Chem. Soc. 125, 16340-16346.
-
-
-
-
21
-
-
0037181030
-
Catalytic Mechanism of Heme Oxygenase through EPR and ENDOR of Cryoreduced Oxy-Heme Oxygenase and its Asp140 Mutants
-
Davydov, R., Kofman, V., Fujii, H., Yoshida, T., Ikeda-Saito, M., and Hoffman, B. (2002) Catalytic Mechanism of Heme Oxygenase through EPR and ENDOR of Cryoreduced Oxy-Heme Oxygenase and its Asp140 Mutants. J. Am. Chem. Soc. 124, 1798-1808.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 1798-1808
-
-
Davydov, R.1
Kofman, V.2
Fujii, H.3
Yoshida, T.4
Ikeda-Saito, M.5
Hoffman, B.6
-
22
-
-
10344264502
-
Proton Transfer at Helium Temperatures during Dioxygen Activation by Heme Monooxygenases
-
Davydov, R., Chemerisov, S., Werst, D. E., Rajh, T., Matsui, T., Ikeda-Saito, M., and Hoffman, B. M. (2004) Proton Transfer at Helium Temperatures during Dioxygen Activation by Heme Monooxygenases. J. Am. Chem. Soc. 126, 15960-15961.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 15960-15961
-
-
Davydov, R.1
Chemerisov, S.2
Werst, D.E.3
Rajh, T.4
Matsui, T.5
Ikeda-Saito, M.6
Hoffman, B.M.7
-
23
-
-
0035853766
-
Cryotrapped reaction intermediates of cytochrome P450 studied by radiolytic reduction with phosphorus-32
-
Denisov, I. G., Makris, T. M., and Sligar, S. G. (2001) Cryotrapped reaction intermediates of cytochrome P450 studied by radiolytic reduction with phosphorus-32. J. Biol. Chem. 276, 11648-11652.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 11648-11652
-
-
Denisov, I.G.1
Makris, T.M.2
Sligar, S.G.3
-
24
-
-
0141988883
-
Determination of the Rate of Reduction of Oxyferrous Cytochrome P450 2B4 by 5-Deazariboflavin Adenine Dinucleotide T491V Cytochrome P450 Reductase
-
Zhang, H., Gruenke, L., Arscott, D., Shen, A., Kasper, C., Harris, D. L., Glavanovich, M., Johnson, R., and Waskell, L. (2003) Determination of the Rate of Reduction of Oxyferrous Cytochrome P450 2B4 by 5-Deazariboflavin Adenine Dinucleotide T491V Cytochrome P450 Reductase. Biochemistry 42, 11594-11603.
-
(2003)
Biochemistry
, vol.42
, pp. 11594-11603
-
-
Zhang, H.1
Gruenke, L.2
Arscott, D.3
Shen, A.4
Kasper, C.5
Harris, D.L.6
Glavanovich, M.7
Johnson, R.8
Waskell, L.9
-
25
-
-
33846820279
-
Distinct Reaction Pathways Followed upon Reduction of Oxy-Heme Oxygenase and Oxy-Myoglobin as Characterized by Moessbauer Spectroscopy
-
Garcia-Serres, R., Davydov, R. M., Matsui, T., Ikeda-Saito, M., Hoffman, B. M., and Huynh, B. H. (2007) Distinct Reaction Pathways Followed upon Reduction of Oxy-Heme Oxygenase and Oxy-Myoglobin as Characterized by Moessbauer Spectroscopy. J. Am. Chem. Soc. 129, 1402-1412.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 1402-1412
-
-
Garcia-Serres, R.1
Davydov, R.M.2
Matsui, T.3
Ikeda-Saito, M.4
Hoffman, B.M.5
Huynh, B.H.6
-
26
-
-
0003852875
-
-
3rd ed, John Wiley & Sons, New York
-
Spinks, J. W. T., and Woods, R. J. (1990) An Introduction to Radiation Chemistry, 3rd ed., John Wiley & Sons, New York.
-
(1990)
An Introduction to Radiation Chemistry
-
-
Spinks, J.W.T.1
Woods, R.J.2
|