Determination of the rate of reduction of oxyferrous cytochrome P450 2B4 by 5-deazariboflavin adenine dinucleotide T491V cytochrome P450 reductase

Biochemistry

Volumn 42, Issue 40, 2003, Pages 11594-11603

  Zhang, Haoming ^a   Gruenke, Larry ^a   Arscott, Dave ^a   Shen, Anna ^b   Kasper, Charles ^b   Harris, Danni L ^c   Glavanovich, Michael ^d   Johnson, Richard ^d   Waskell, Lucy ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c MOLECULAR RESEARCH INSTITUTE   (United States)

^d Avtech Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ELECTRON TRANSITIONS; RATE CONSTANTS; SUBSTRATES;

OXYFERROUS CYTOCHROME;

ENZYMES;

5 DEAZARIBOFLAVIN ADENINE DINUCLEOTIDE T491V CYTOCHROME P450 REDUCTASE; BENZPHETAMINE; CYTOCHROME P450 2B; CYTOCHROME P450 2B4; CYTOCHROME P450 REDUCTASE; FLAVINE MONONUCLEOTIDE; HYDROQUINONE; NORBENZPHETAMINE; REDUCED FLAVINE MONONUCLEOTIDE; SEMIQUINONE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ELECTRON TRANSPORT; ENZYME SUBSTRATE COMPLEX; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REDUCTION;

ARYL HYDROCARBON HYDROXYLASES; BENZPHETAMINE; CATALYSIS; CYTOCHROMES B5; ELECTRON TRANSPORT; FERROUS COMPOUNDS; FLAVIN-ADENINE DINUCLEOTIDE; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; OXYGEN; SUBSTRATE SPECIFICITY; THREONINE; VALINE;

EID: 0141988883     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034968u     Document Type: Article

References (41)

1. Ortiz de Montellano, P. R. (1995) in Cytochrome P450: Structure, Mechanism and Biochemistry (Ortiz de Montellano, P. R., Ed.) 2nd ed., pp 245-304, Plenum Press, New York.
2. Guengerich, F. P. (2001) Chem. Res. Toxicol. 14, 611-650.
3. White, R. E., and Coon, M. J. (1980) Annu. Rev. Biochem. 49, 315-356.
4. Guengerich, F. P., Miller, G. P., Hanna, I. H., Sato, H., and Martin, M. V. (2002) J. Biol. Chem. 277, 33711-33719.
5. Davydov, R., Makris, T. M., Kofman, V., Werst, D. E., Sligar, S. G., and Hoffmann, B. M. (2001) J. Am. Chem. Soc. 123, 1403-1415.
6. Denisov, I. G., Makris, T. M., and Sligar, S. G. (2001) J. Biol. Chem. 276, 11648-52.
7. Brewer, C. B., and Peterson, J. A. (1988) Arch. Biochem. Biophys. 263, 791-798.
8. Oprian, D. D., and Coon, M. J. (1982) J. Biol. Chem. 257, 8935-8944.
9. Newcomb, M., Hollenberg, P., and Coon, M. (2003) Arch. Biochem. Biophys. 409, 72-79.
10. Bonfils, C., Balny, C., and Maurel, P. (1981) J. Biol. Chem. 256, 9457-9465.
11. Guengerich, F. P., Ballou, D. P., and Coon, J. J. (1975) J. Biol. Chem. 250, 7405-7414.
12. Pompon, D., and Coon, M. J. (1984) J. Biol. Chem. 259, 15377-15385.
13. Gruenke, L. D., Konopka, K., Cadieu, M., and Waskell, L. (1995) J. Biol. Chem. 270, 24707-24718.
14. Canova-Davis, E., Chiang, J. Y., and Waskell, L. (1985) Biochem. Pharmacol. 34, 1907-1912.
15. Canova-Davis, E., and Waskell, L. (1984) J. Biol. Chem. 259, 2541-2546.
16. Zhang, H., Gruenke, L., Saribas, A. S., Im, S.-C., Shen, A. L., Kasper, C. F., and Waskell, L. (2003) Biochemistry 42, 6804-6813.
17. Shen, A. L., and Kasper, C. B. (2000) J. Biol. Chem. 275, 41087-41091.
18. Saribas, A. S., Gruenke, L. D., and Waskell, L. (2001) Protein Expression Purif. 21, 303-309.
19. Mulrooney, S. B., and Waskell, L. (2000) Protein Expression Purif. 19, 173-178.
20. Omura, T., and Sato, R. (1964) J. Biol. Chem. 239, 2370-2378.
21. Estabrook, R. W., and Werringloer, J. (1978) Methods Enzymol. 52, 212-220.
22. Hodek, P., and Strobel, H. W. (1994) Bioorg. Chem. 22, 253-267.
23. Hartung, C. G., Breindl, C., Tillack, A., and Beller, M. (2000) Tetrahedron 56, 5157-5162.
24. Bridges, A., Gruenke, L., Chang, Y. T., Vakser, I. A., Loew, G., and Waskell L. (1998) J. Biol. Chem. 273, 17036-17049.
25. Bonfils, C., Debey, P., and Maurel, P. (1979) Biochem. Biophys. Res. Commun. 88, 1301-1307.
26. Lambeir, A. M., Appleby, C. A., and Dunford, H. B. (1985) Biochim. Biophys. Acta 828, 144-150.
27. Strittmatter, P., and Velick, S. F. (1956) J. Biol. Chem. 221, 253-264.
28. Vermilion, J. L., and Coon, M. J. (1978) J. Biol. Chem. 253, 8812-8819.
29. Lewis, D. F. V. (1996) in Cytochromes P450, p 102, Taylor and Francis, Bristol.
30. Hildebrandt, A., and Estabrook, R. W. (1971) Arch. Biochem. Biophys. 143, 66-79.
31. Schenkman, J. B., and Jansson, I. (2003) Pharmacol. Ther. 97, 139-152.
32. Harris, D. L., and Loew, G. H. (1998) J. Am. Chem. Soc. 120, 8941-8948.
33. Schlichting, I., Berendzen, J., Chu, K., Stock, A. M., Maves, S. A., Benson, D. E., Sweet, R. M., Ringe, D., Petsko, G. A., and Sligar, S. G. (2000) Science 287, 1615-1622.
34. Tamburini, P., and Gibson, G. (1983) J. Biol. Chem. 258, 13444-13452.
35. Haines, D. C., Tomchick, D. R., Machius, M., and Peterson, J. A. (2001) Biochemistry 40, 13456-13465.
36. Pochapsky, S. S., Pochapsky, T. C., and Wei, J. W. (2003) Biochemistry 42, 5649-5656.
37. French, J. S., Guengerich, F. P., and Coon, M. J. (1980) J. Biol. Chem. 255, 4112-4119.
38. Strobel, H. W., Hodgson, A. V., and Shen, S. (1995) in Cytochrome P450: Structure, Mechanism and Biochemistry, 2nd ed., p 225, Plenum Press, New York.
39. Wolthers, K., Basran, J., Munro, A., and Scrutton, N. (2003) Biochemistry 42, 3911-3920.
40. Ludwig, M., and Luschinsky, C. L. (1992) Structure and redox properties of clostridial flavodoxins, in Chemistry and Biochemistry of Flavoenzymes (Mueller, F., Ed.) Vol. 3, pp 427-466, CRC Press, Boca Raton, FL.
41. Park, J.-Y., and Harris, D. (2003) J. Med. Chem. 46, 1645-1660.