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1
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334443 Mechanisms of resistance to azole antifungal compounds. Marichal P CURR OPIN ANTI-INFECTIVE INVEST DRUGS 1999 1 3 318-333
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334443 Mechanisms of resistance to azole antifungal compounds. Marichal P CURR OPIN ANTI-INFECTIVE INVEST DRUGS 1999 1 3 318-333
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2
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405646 Effects of the antifungal agents on oxidative drug metabolism: Clinical relevance. Venkatakrishnan K, von Moltke LL, Greenblatt DJ CLIN PHARMACOKINET 2000 38 2 111-180
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405646 Effects of the antifungal agents on oxidative drug metabolism: Clinical relevance. Venkatakrishnan K, von Moltke LL, Greenblatt DJ CLIN PHARMACOKINET 2000 38 2 111-180
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588942 The novel azole R-126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp and Microsporum canis. Bossche HV, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, Meerpoel L, Odds F, Borgers M ANTIMICROB AGENTS CHEMOTHER 2004 48 9 3272-3278
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588942 The novel azole R-126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp and Microsporum canis. Bossche HV, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, Meerpoel L, Odds F, Borgers M ANTIMICROB AGENTS CHEMOTHER 2004 48 9 3272-3278
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588946 In vitro and in vivo activities of novel azole antifungal agent R-126638. Odds F, Ausma J, Van Gerven F, Woestenborghs F, Meerpoel L, Heeres J, Vanden Bossche H, Borgers M ANTIMICROB AGENTS CHEMOTHER 2004 48 2 388-391 • This article provides a comprehensive evaluation of the potency of pramiconazole in vitro and in vivo in animal models of cutaneous infection. In vivo, pramiconazole demonstrated superior antifungal activity compared with itraconazole, with ED50 values that were 3- to 8-fold lower than with itraconazole
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50 values that were 3- to 8-fold lower than with itraconazole.
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588979 Form S-1/A, Barrier Therapeutics Inc. Barrier Therapeutics Inc FORM S-1 2004 March 15
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588979 Form S-1/A - Barrier Therapeutics Inc. Barrier Therapeutics Inc FORM S-1 2004 March 15
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20144379891
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622113 Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology. Meerpoel L, Backx LJ, Van der Veken LJ, Heeres J, Corens D, De Groot A, Odds FC, Van Gerven F, Woestenborghs FA, Van Breda A J MED CHEM 2005 48 6 2184-2193
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622113 Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology. Meerpoel L, Backx LJ, Van der Veken LJ, Heeres J, Corens D, De Groot A, Odds FC, Van Gerven F, Woestenborghs FA, Van Breda A J MED CHEM 2005 48 6 2184-2193
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657938 Activity of the triazole antifungal R-126638 as assessed by corneofungimetry. Pierard-Franchimont C, Ausma J, Wouters L, Vroome V, Vandeplassche L, Borgers M, Cauwenbergh G, Pierard GE SKIN PHARMACOL PHYSIOL 2006 19 1 50-56 • This article describes a study assessing levels of pramiconazole in epidermal stratum corneum using corneofungimetry. Informative data were obtained regarding the persistence of pramiconazole in the skin despite the cessation of treatment
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657938 Activity of the triazole antifungal R-126638 as assessed by corneofungimetry. Pierard-Franchimont C, Ausma J, Wouters L, Vroome V, Vandeplassche L, Borgers M, Cauwenbergh G, Pierard GE SKIN PHARMACOL PHYSIOL 2006 19 1 50-56 • This article describes a study assessing levels of pramiconazole in epidermal stratum corneum using corneofungimetry. Informative data were obtained regarding the persistence of pramiconazole in the skin despite the cessation of treatment.
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762420 NexMed announces patient dosing in phase 3 program for anti-fungal product. NexMed Inc PRESS RELEASE 2007 February 01
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762420 NexMed announces patient dosing in phase 3 program for anti-fungal product. NexMed Inc PRESS RELEASE 2007 February 01
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783614 A pilot study on seborrheic dermatitis using pramiconazole as a potent oral anti-Malassezia agent. Pierard GE, Ausma J, Henry F, Vroome V, Wouters L, Borgers M, Cauwenbergh G, Pierard-Franchimont C DERMATOLOGY 2007 214 2 162-169
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783614 A pilot study on seborrheic dermatitis using pramiconazole as a potent oral anti-Malassezia agent. Pierard GE, Ausma J, Henry F, Vroome V, Wouters L, Borgers M, Cauwenbergh G, Pierard-Franchimont C DERMATOLOGY 2007 214 2 162-169
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51049099871
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814103 The efficacy of oral treatment with pramiconazole in pityriasis versicolor: A phase IIa trial. Faergemann J, Ausma J, Vandeplassche L, Borgers M BR J DERMATOL 2007 156 6 1385-1388
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814103 The efficacy of oral treatment with pramiconazole in pityriasis versicolor: A phase IIa trial. Faergemann J, Ausma J, Vandeplassche L, Borgers M BR J DERMATOL 2007 156 6 1385-1388
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834241 Barrier's phase III Hyphanox trial for onychomycosis fully enrolled. Barrier Therapeutics Inc PRESS RELEASE 2007 September 28
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834241 Barrier's phase III Hyphanox trial for onychomycosis fully enrolled. Barrier Therapeutics Inc PRESS RELEASE 2007 September 28
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841003 Barrier Therapeutics announces promising results from ongoing phase 2a study of pramiconazole in onychomycosis. Barrier Therapeutics Inc PRESS RELEASE 2007 October 19
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841003 Barrier Therapeutics announces promising results from ongoing phase 2a study of pramiconazole in onychomycosis. Barrier Therapeutics Inc PRESS RELEASE 2007 October 19
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845028 Form 10K for the year ended 31 December 2006. Barrier Therapeutics Inc FORM 10-K 2007 March 12
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845028 Form 10K for the year ended 31 December 2006. Barrier Therapeutics Inc FORM 10-K 2007 March 12
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878515 Pramiconazole, a novel oral antifungal agent, effectively treats pityriasis versicolor: Results of a dose-finding clinical study. Faergemann J, Borgers M, Barranco C, Spellman M J AM ACAD DERMATOL 2008 58 2 Suppl 2 Abs P1704 •• This article describes the first large-scale, dose-finding clinical trial assessing several regimens of pramiconazole in patients with tinea versicolor. A linear dose-response relationship for treatment effectiveness was observed, and pramiconazole was determined to be generally well tolerated
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878515 Pramiconazole, a novel oral antifungal agent, effectively treats pityriasis versicolor: Results of a dose-finding clinical study. Faergemann J, Borgers M, Barranco C, Spellman M J AM ACAD DERMATOL 2008 58 2 Suppl 2 Abs P1704 •• This article describes the first large-scale, dose-finding clinical trial assessing several regimens of pramiconazole in patients with tinea versicolor. A linear dose-response relationship for treatment effectiveness was observed, and pramiconazole was determined to be generally well tolerated.
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880130 Absence of an active metabolite for the triazole antifungal pramiconazole. Ausma J, Pennick G, Bohets H, van de Velde Vera BM, Fothergill A ACTA DERM VENEREOL SUPPL 2007 87 1 22-26
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880130 Absence of an active metabolite for the triazole antifungal pramiconazole. Ausma J, Pennick G, Bohets H, van de Velde Vera BM, Fothergill A ACTA DERM VENEREOL SUPPL 2007 87 1 22-26
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880131 In vitro activity of R-126638 and ketoconazole against Malassezia species. Faergemann J, Ausma J, Borgers M ACTA DERM VENEREOL SUPPL 2006 86 4 312-315
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880131 In vitro activity of R-126638 and ketoconazole against Malassezia species. Faergemann J, Ausma J, Borgers M ACTA DERM VENEREOL SUPPL 2006 86 4 312-315
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888381 NanoBio Corporation completes interim analysis of phase 2 clinical trial in onychomycosis. NanoBio Corp PRESS RELEASE 2008 March 20
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888381 NanoBio Corporation completes interim analysis of phase 2 clinical trial in onychomycosis. NanoBio Corp PRESS RELEASE 2008 March 20
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900966 Barrier Therapeutics announces first quarter 2008 financial results. Barrier Therapeutics Inc PRESS RELEASE 2008 April 29
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900966 Barrier Therapeutics announces first quarter 2008 financial results. Barrier Therapeutics Inc PRESS RELEASE 2008 April 29
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910792 York Pharma plc, York Pharma' or 'the Company, York Pharma plc PRESS RELEASE 2008 May 28
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910792 York Pharma plc ('York Pharma' or 'the Company'). York Pharma plc PRESS RELEASE 2008 May 28
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916327 The efficacy of oral treatment with pramiconazole in tinea pedis and tinea cruris/corporis: Two exploratory phase IIa trials. Decroix J, Ausma J, Cauwenbergh G, Borgers M, Wouters L BR J DERMATOL 2008 158 4 854-856
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919320 Stiefel plans $148 million acquisition of Barrier Therapeutics. Stiefel Laboratories Inc PRESS RELEASE 2008 June 23
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919320 Stiefel plans $148 million acquisition of Barrier Therapeutics. Stiefel Laboratories Inc PRESS RELEASE 2008 June 23
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919911 Schering-Plough, Product pipeline, June 2008. Schering-Plough Corp COMPANY WORLD WIDE WEB SITE 2008 June 10
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919911 Schering-Plough - Product pipeline - June 2008. Schering-Plough Corp COMPANY WORLD WIDE WEB SITE 2008 June 10
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923524 Itraconazole for the treatment of tinea pedis: A dosage of 400 mg/day given for 1 week is similar in efficacy to 100 or 200 mg/day given for 2 to 4 weeks. Gupta AK, Doncker PD, Heremans A, Stoffels P, Pierard GE, Decroix J, Heenen M, Degreef H J AM ACAD DERMATOL 1997 36 5 Pt 1 789-792
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923536 A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs. Garcia-Rodriguez LA, Duque A, Castellsague J, Perez-Gutthann S, Stricker BH BR J CLIN PHARMACOL 1999 48 6 847-852
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923536 A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs. Garcia-Rodriguez LA, Duque A, Castellsague J, Perez-Gutthann S, Stricker BH BR J CLIN PHARMACOL 1999 48 6 847-852
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923544 Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents. Lamb DC, Kelly DE, Baldwin BC, Kelly SL CHEM BIOL INTERACT 2000 125 3 165-175
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924541 Post-treatment levels of pramiconazole, a new oral antifungal, in nails. Ausma J, Vandeplassche G, Bruynseels J, Grindel M CONGR EUR ACAD DERMATOL VENEREOL 2006 October 4-7 Abs P014.9
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924541 Post-treatment levels of pramiconazole, a new oral antifungal, in nails. Ausma J, Vandeplassche G, Bruynseels J, Grindel M CONGR EUR ACAD DERMATOL VENEREOL 2006 October 4-7 Abs P014.9
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931375 Chapter 48: Antifungal Agents. Bennet JE GOODMAN & GILMANS THE PHARMACOLOGICAL BASIS OF THERAPEUTICS (EDS: BRUNTON LL, LAZO JS, PARKER KL) 2005 McGraw-Hill, New York 11th Edition 1225-1242
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931375 Chapter 48: Antifungal Agents. Bennet JE GOODMAN & GILMANS THE PHARMACOLOGICAL BASIS OF THERAPEUTICS (EDS: BRUNTON LL, LAZO JS, PARKER KL) 2005 McGraw-Hill, New York 11th Edition 1225-1242
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931376 Role of antifungal agents in the treatment of seborrheic dermatitis. Gupta AK, Nicol K, Batra R AM J CLIN DERMATOL 2004 5 6 417-422
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931376 Role of antifungal agents in the treatment of seborrheic dermatitis. Gupta AK, Nicol K, Batra R AM J CLIN DERMATOL 2004 5 6 417-422
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931381 Prevalence and epidemiology of onychomycosis. Vender RB, Lynde CW, Poulin Y J CUT MED SURG 2006 10 Suppl 2 28-33
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931381 Prevalence and epidemiology of onychomycosis. Vender RB, Lynde CW, Poulin Y J CUT MED SURG 2006 10 Suppl 2 28-33
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931384 Cutaneous infections dermatophytosis, onychomycosis and tinea versicolor. Vander Straten MR, Hossain MA, Ghannoum MA INFECT DIS CLIN N AM 2003 17 1 87-112
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931386 Etiology and management of seborrheic dermatitis. Gupta AK, Madzia SE, Batra R DERMATOLOGY 208 2 89-93
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931386 Etiology and management of seborrheic dermatitis. Gupta AK, Madzia SE, Batra R DERMATOLOGY 208 2 89-93
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932296 Stiefel Laboratories completes acquisition of Barrier Therapeutics. Stiefel Laboratories Inc PRESS RELEASE 2008 August 06
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932296 Stiefel Laboratories completes acquisition of Barrier Therapeutics. Stiefel Laboratories Inc PRESS RELEASE 2008 August 06
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