-
1
-
-
0942268851
-
-
Odds F, Ausma J, Van Gerven F, Woestenborghs, Meerpoel L, Heerens J, et al. Activity in vitro and in vivo of a novel azole antifungal agent R126638 Antimicrob Agents Chemother 2004; 43: 388-391.
-
Odds F, Ausma J, Van Gerven F, Woestenborghs, Meerpoel L, Heerens J, et al. Activity in vitro and in vivo of a novel azole antifungal agent R126638 Antimicrob Agents Chemother 2004; 43: 388-391.
-
-
-
-
2
-
-
4344704026
-
The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp. and Microsporum canis
-
Vanden Bossche H, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, et al. The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp. and Microsporum canis. Antimicrob Agents Chemother 2004; 48: 3272-3278.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3272-3278
-
-
Vanden Bossche, H.1
Ausma, J.2
Bohets, H.3
Vermuyten, K.4
Willemsens, G.5
Marichal, P.6
-
3
-
-
0026761973
-
Primary cultures of human hepatocytes: A unique system for studies in toxicology, virology, parasitology and liver pathophysiology in man
-
Moshage H, Yap SH. Primary cultures of human hepatocytes: a unique system for studies in toxicology, virology, parasitology and liver pathophysiology in man. J Hepatol 1992; 15: 404-413.
-
(1992)
J Hepatol
, vol.15
, pp. 404-413
-
-
Moshage, H.1
Yap, S.H.2
-
4
-
-
0027500871
-
Discrepancies in bioassay and chromatography determinations explained by metabolism of itraconazole to hydroxyitraconazole: Studies of interpatient varieties in concentrations
-
Hostetler JS, Heykants J, Clemons KV, Woestenborghs R, Hanson LH, Stevens DA. Discrepancies in bioassay and chromatography determinations explained by metabolism of itraconazole to hydroxyitraconazole: studies of interpatient varieties in concentrations. Antimicrob Agents Chemother 1993; 37: 2224-2227.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 2224-2227
-
-
Hostetler, J.S.1
Heykants, J.2
Clemons, K.V.3
Woestenborghs, R.4
Hanson, L.H.5
Stevens, D.A.6
-
5
-
-
0029380499
-
Determination of itraconazole and hydroxy-itraconazole in sera using high-performance liquid chromatography and a bioassay
-
Hülsewede JW, Dermmouni H, Ansorg R. Determination of itraconazole and hydroxy-itraconazole in sera using high-performance liquid chromatography and a bioassay. Zentralbl Bakteriol 1995; 282: 457-464.
-
(1995)
Zentralbl Bakteriol
, vol.282
, pp. 457-464
-
-
Hülsewede, J.W.1
Dermmouni, H.2
Ansorg, R.3
-
6
-
-
0032949890
-
Bioassay for itraconazole blood levels: An interlaboratory collaborative study
-
Odds FC, Dupont B, Rinaldi MG, Stevens DA, Warnock DW, Woestenborghs R. Bioassay for itraconazole blood levels: an interlaboratory collaborative study. Antimicrob Chemother 1999; 43: 723-727.
-
(1999)
Antimicrob Chemother
, vol.43
, pp. 723-727
-
-
Odds, F.C.1
Dupont, B.2
Rinaldi, M.G.3
Stevens, D.A.4
Warnock, D.W.5
Woestenborghs, R.6
-
7
-
-
28744448650
-
Placebo-controlled randomized double-blind multiple dose dose-rising trial in healthy volunteers to assess the tolerability, safety and pharmacokinetics of the novel antifungal R126638
-
Ausma J, Bruynseels J, Snoeck E, Blockhuys S, van Rossem K, Borgers M. Placebo-controlled randomized double-blind multiple dose dose-rising trial in healthy volunteers to assess the tolerability, safety and pharmacokinetics of the novel antifungal R126638. J Eur Acad Derm Venereol 2004; 18 (suppl. 2): 392.
-
(2004)
J Eur Acad Derm Venereol
, vol.18
, Issue.SUPPL. 2
, pp. 392
-
-
Ausma, J.1
Bruynseels, J.2
Snoeck, E.3
Blockhuys, S.4
van Rossem, K.5
Borgers, M.6
-
8
-
-
0034002752
-
Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: In vitro studies of potential co-medication interactions
-
Bohets H, Lavrijsen K, Hendrickx J, Van Houdt J, van Genechten V, Verboven P, et al. Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions. Br J Pharmacol 2000; 129: 1655-1667.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1655-1667
-
-
Bohets, H.1
Lavrijsen, K.2
Hendrickx, J.3
Van Houdt, J.4
van Genechten, V.5
Verboven, P.6
-
10
-
-
9844256470
-
Protein determination for large number samples
-
Miller GL. Protein determination for large number samples. Anal Chem 1959; 31: 964.
-
(1959)
Anal Chem
, vol.31
, pp. 964
-
-
Miller, G.L.1
-
11
-
-
50449100139
-
The carbon monoxide pigment of liver microsomes. II. Solubilization, purification and properties
-
Omura T, Sato R. The carbon monoxide pigment of liver microsomes. II. Solubilization, purification and properties. J Biol Chem 1964; 239: 2379-2385.
-
(1964)
J Biol Chem
, vol.239
, pp. 2379-2385
-
-
Omura, T.1
Sato, R.2
-
12
-
-
0015409143
-
2+ on enzymatic dispersion of isolated perfused liver
-
2+ on enzymatic dispersion of isolated perfused liver. Exp Cell Res 1972; 74: 450-454.
-
(1972)
Exp Cell Res
, vol.74
, pp. 450-454
-
-
Seglen, P.O.1
-
13
-
-
0019847093
-
Isolation and culture of adult hepatocytes from liver biopsies
-
Reese JA, Byard JL. Isolation and culture of adult hepatocytes from liver biopsies. In Vitro 1981; 17: 935-940.
-
(1981)
In Vitro
, vol.17
, pp. 935-940
-
-
Reese, J.A.1
Byard, J.L.2
-
14
-
-
0021877049
-
Simplified bioassay method for measurement of flucytosine or ketoconazole
-
Bodet CA, Jorgensen JH, Drutz DJ. Simplified bioassay method for measurement of flucytosine or ketoconazole. J Clin Microbiol 1985; 22: 157-160.
-
(1985)
J Clin Microbiol
, vol.22
, pp. 157-160
-
-
Bodet, C.A.1
Jorgensen, J.H.2
Drutz, D.J.3
-
15
-
-
84988175795
-
Analytical methods validation: Bioavailability, bioequivalence, and pharmacokinetic studies
-
Shah V, Midha K, Dighe S, McGilveray I, Skelly J, Yacobi A, et al. Analytical methods validation: bioavailability, bioequivalence, and pharmacokinetic studies. J Pharmaceutical Sci 1992; 81: 309-312.
-
(1992)
J Pharmaceutical Sci
, vol.81
, pp. 309-312
-
-
Shah, V.1
Midha, K.2
Dighe, S.3
McGilveray, I.4
Skelly, J.5
Yacobi, A.6
-
16
-
-
33846891003
-
Guidance for Industry. Bioanalytical method validation. US Department of Health and Human Services. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Veterinary
-
May
-
Guidance for Industry. Bioanalytical method validation. US Department of Health and Human Services. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM), May 2001.
-
(2001)
Medicine
, vol.1095
-
-
-
17
-
-
0001362120
-
The kinetics of ketoconazole in animals and man
-
Gascoigne EW, Barton GJ, Michaels M, Meuldermans W, Heykants J. The kinetics of ketoconazole in animals and man. Clin Res Rev 1981; 1: 177-187.
-
(1981)
Clin Res Rev
, vol.1
, pp. 177-187
-
-
Gascoigne, E.W.1
Barton, G.J.2
Michaels, M.3
Meuldermans, W.4
Heykants, J.5
-
18
-
-
33846852758
-
Fluconazole: An overview
-
Fluconazole and its role in vaginal candidiasis. Richardson RG, ed, London: Royal Society of Medicine Services
-
Feczko J: Fluconazole: an overview; In: Fluconazole and its role in vaginal candidiasis. Richardson RG, ed. International Congress and Symposium Series No. 160. London: Royal Society of Medicine Services, 1989: p. 11-18.
-
(1989)
International Congress and Symposium Series
, vol.160
, pp. 11-18
-
-
Feczko, J.1
-
19
-
-
4644321613
-
Role of itraconazole metabolites in CYP3A4 inhibition
-
Isoherranen N, Kunze KL, Allen KE, Nelson WL, Thummel KE. Role of itraconazole metabolites in CYP3A4 inhibition. Drug Metab Dispos. 2004; 32: 1121-1131.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1121-1131
-
-
Isoherranen, N.1
Kunze, K.L.2
Allen, K.E.3
Nelson, W.L.4
Thummel, K.E.5
-
20
-
-
0024847184
-
The clinical pharmacokinetics of itraconazole: An overview
-
Heykants J, Van Peer A, Van de Velde V, Van Rooy P, Meuldermans W, Lavrijsen K, et al. The clinical pharmacokinetics of itraconazole: an overview. Mycosis 1989; 32 (suppl 1): 67-87.
-
(1989)
Mycosis
, vol.32
, Issue.SUPPL. 1
, pp. 67-87
-
-
Heykants, J.1
Van Peer, A.2
Van de Velde, V.3
Van Rooy, P.4
Meuldermans, W.5
Lavrijsen, K.6
|