-
1
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
The ENCODE Project Consortium
-
The ENCODE Project Consortium (2007) Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature, 447, 799-816.
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
-
2
-
-
0024263822
-
The formation and function of DNase 1 hypersensitive sites in the process of gene activation
-
Elgin,S.C. (1988) The formation and function of DNase 1 hypersensitive sites in the process of gene activation. J. Biol. Chem., 263 19259-19262.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 19259-19262
-
-
Elgin, S.C.1
-
3
-
-
0017142124
-
Chromosomal subunits in active genes have an altered conformation
-
Weintraub,H. and Groudine,M. (1976) Chromosomal subunits in active genes have an altered conformation. Science, 193, 848-856.
-
(1976)
Science
, vol.193
, pp. 848-856
-
-
Weintraub, H.1
Groudine, M.2
-
4
-
-
0019303186
-
The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I
-
Wu,C. (1980) The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I. Nature, 286, 854-860.
-
(1980)
Nature
, vol.286
, pp. 854-860
-
-
Wu, C.1
-
5
-
-
10744232248
-
Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites
-
Crawford,G.E., Holt,I.E., Mullikin,J.C., Tai,D., Blakesley,R., Bouffard,G., Young,A., Masiello,C., Green,E.D., Wolfsberg,T.G. et al. (2004) Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. Proc. Natl Acad. Sci. USA, 101 992-997.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 992-997
-
-
Crawford, G.E.1
Holt, I.E.2
Mullikin, J.C.3
Tai, D.4
Blakesley, R.5
Bouffard, G.6
Young, A.7
Masiello, C.8
Green, E.D.9
Wolfsberg, T.G.10
-
6
-
-
1842532951
-
Genome-wide identification of DNasel hypersensitive sites usinr active chromatin sequence libraries
-
Sabo,P.J., Humbert,R., Hawrylycz,M., Wallace,J.C., Dorschner,M.O., McArthur,M. and Stamatoyannopoulos,J.A. (2004) Genome-wide identification of DNasel hypersensitive sites usinr active chromatin sequence libraries. Proc. Natl Acad. Sci. USA, 101, 4537-4542.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 4537-4542
-
-
Sabo, P.J.1
Humbert, R.2
Hawrylycz, M.3
Wallace, J.C.4
Dorschner, M.O.5
McArthur, M.6
Stamatoyannopoulos, J.A.7
-
7
-
-
20844435623
-
-
Dorschner,M.O., Hawrylycz,M., Humbert.R., Wallace,J.C., Shafer,A., Kawamoto,J., Mack,J., Hall,R., Goldy,J., Sabo,P.J. et al. (2004) High-throughput localization of functional elements by quantitative chromatin profiling. Nat. Methods, 1, 219-225.
-
Dorschner,M.O., Hawrylycz,M., Humbert.R., Wallace,J.C., Shafer,A., Kawamoto,J., Mack,J., Hall,R., Goldy,J., Sabo,P.J. et al. (2004) High-throughput localization of functional elements by quantitative chromatin profiling. Nat. Methods, 1, 219-225.
-
-
-
-
8
-
-
33745409293
-
DNase-chip: A high-resolution method to identify DNase I hypersensitive sites using tiled microarrays
-
Crawford,G.E., Davis,S., Scacheri,P.C., Renaud,G., Halawi,M.J., Erdos,M.R., Green,R., Meltzer,P.S., Wolfsberg,T.G. and Collins,F.S. (2006) DNase-chip: A high-resolution method to identify DNase I hypersensitive sites using tiled microarrays. Nat. Methods, 3 503-509.
-
(2006)
Nat. Methods
, vol.3
, pp. 503-509
-
-
Crawford, G.E.1
Davis, S.2
Scacheri, P.C.3
Renaud, G.4
Halawi, M.J.5
Erdos, M.R.6
Green, R.7
Meltzer, P.S.8
Wolfsberg, T.G.9
Collins, F.S.10
-
9
-
-
33749392739
-
Identifying gene regulatory elements by genomic microarray mapping of DNase I hypersensitive sites
-
Follows,G.A., Dhami,P., Gottgens,B., Bruce,A.W., Campbell,P-J., Dillon,S.C., Smith,A.M., Koch,C., Donaldson,I.J., Scott,M.A. et al. (2006) Identifying gene regulatory elements by genomic microarray mapping of DNase I hypersensitive sites. Genome Res., 16, 1310-1319.
-
(2006)
Genome Res
, vol.16
, pp. 1310-1319
-
-
Follows, G.A.1
Dhami, P.2
Gottgens, B.3
Bruce, A.W.4
Campbell, P.-J.5
Dillon, S.C.6
Smith, A.M.7
Koch, C.8
Donaldson, I.J.9
Scott, M.A.10
-
10
-
-
33745416080
-
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays
-
Sabo,P.J., Kuehn,M.S., Thurman,R., Johnson,B.E., Johnson,E.M., Cao,H., Yu,M., Rosenzweig,E., Goldy,J., Haydock,A. et al. (2006) Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays. Nat. Meth., 3, 511-518.
-
(2006)
Nat. Meth
, vol.3
, pp. 511-518
-
-
Sabo, P.J.1
Kuehn, M.S.2
Thurman, R.3
Johnson, B.E.4
Johnson, E.M.5
Cao, H.6
Yu, M.7
Rosenzweig, E.8
Goldy, J.9
Haydock, A.10
-
11
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
Tracey,K.J. and Cerami,A. (1993) Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol., 9, 317-343.
-
(1993)
Annu. Rev. Cell Biol
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
12
-
-
0025015479
-
TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria
-
Kwiatkowski,D., Hill,A.V.S., Sambou,I., Twumasi,P., Castracane,J., Manogue,K.R., Cerami,A., Brewster,D.R. and Greenwood,B.M. (1990) TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet, 336, 1201-1204.
-
(1990)
Lancet
, vol.336
, pp. 1201-1204
-
-
Kwiatkowski, D.1
Hill, A.V.S.2
Sambou, I.3
Twumasi, P.4
Castracane, J.5
Manogue, K.R.6
Cerami, A.7
Brewster, D.R.8
Greenwood, B.M.9
-
13
-
-
0030818051
-
Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice
-
Neurath,M.F., Fuss,I., Pasparakis,M., Alexopoulou,L., Haralambous,S., Meyer zum Buschenfelde,K.H., Strober,W. and Kollias,G. (1997) Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice. Eur. J. Immunol., 27, 1743-1750.
-
(1997)
Eur. J. Immunol
, vol.27
, pp. 1743-1750
-
-
Neurath, M.F.1
Fuss, I.2
Pasparakis, M.3
Alexopoulou, L.4
Haralambous, S.5
Meyer zum Buschenfelde, K.H.6
Strober, W.7
Kollias, G.8
-
14
-
-
0024314554
-
Inhibitory effect of TNF alpha antibodies, on synovial cell interleukin-1 production in rheumatoid arthritis
-
Brennan,F.M., Chantry,D., Jackson,A., Maini,R. and Feldmann,M. (1989) Inhibitory effect of TNF alpha antibodies, on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet, 2, 244-247.
-
(1989)
Lancet
, vol.2
, pp. 244-247
-
-
Brennan, F.M.1
Chantry, D.2
Jackson, A.3
Maini, R.4
Feldmann, M.5
-
15
-
-
0036203474
-
Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes
-
Tsytsykova,A.V. and Goldfeld,A.E. (2002) Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes. Mol. Cell Biol., 22, 2620-2631.
-
(2002)
Mol. Cell Biol
, vol.22
, pp. 2620-2631
-
-
Tsytsykova, A.V.1
Goldfeld, A.E.2
-
16
-
-
0033998440
-
Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter
-
Falvo,J.V., Uglialoro,A.M., Brinkman,B.M., Merika,M., Parekh,B.S., Tsai,E.Y., King,H.C., Morielli,A.D., Peralta,E.G., Maniatis,T. et al. (2000) Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter. Mol. Cell Biol., 20, 2239-2247.
-
(2000)
Mol. Cell Biol
, vol.20
, pp. 2239-2247
-
-
Falvo, J.V.1
Uglialoro, A.M.2
Brinkman, B.M.3
Merika, M.4
Parekh, B.S.5
Tsai, E.Y.6
King, H.C.7
Morielli, A.D.8
Peralta, E.G.9
Maniatis, T.10
-
17
-
-
0033867980
-
A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recndted to the tumor necrosis factor alpha promoter, in vivo
-
Tsai,E.Y., Falvo,J.V., Tsytsykova,A.V., Barczak,A.K., Reimold,A.M., Glimcher,L.H., Fenton,M.J., Gordon,D.C., Dunn,I.F. and Goldfeld,A.E. (2000) A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recndted to the tumor necrosis factor alpha promoter, in vivo. Mol. Cell Biol., 20 6084-6094.
-
(2000)
Mol. Cell Biol
, vol.20
, pp. 6084-6094
-
-
Tsai, E.Y.1
Falvo, J.V.2
Tsytsykova, A.V.3
Barczak, A.K.4
Reimold, A.M.5
Glimcher, L.H.6
Fenton, M.J.7
Gordon, D.C.8
Dunn, I.F.9
Goldfeld, A.E.10
-
18
-
-
0037218786
-
Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300
-
Barthel,R., Tsytsykova,A.V., Barczak,A.K., Tsai,E.Y., Dascher,C.C., Brenner,M.B. and Goldfeld,A.E. (2003) Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Mol. Cell Biol., 23, 526-533.
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 526-533
-
-
Barthel, R.1
Tsytsykova, A.V.2
Barczak, A.K.3
Tsai, E.Y.4
Dascher, C.C.5
Brenner, M.B.6
Goldfeld, A.E.7
-
19
-
-
0034636022
-
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression
-
Falvo,J.V., Brinkman,B.M., Tslytsykova,A.V., Tsai,E.Y., Yao,T.P., Kung,A.L. and Goldfeld,A.E. (2000) A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression. Proc. Natl Acad. Sci. USA, 97, 3925-3929.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3925-3929
-
-
Falvo, J.V.1
Brinkman, B.M.2
Tslytsykova, A.V.3
Tsai, E.Y.4
Yao, T.P.5
Kung, A.L.6
Goldfeld, A.E.7
-
20
-
-
0141920620
-
T cell-specific expression of the human TNF-alpha gene involves a functional and highly conserved chromatin signature in intron 3
-
Barthel,R. and Goldfeld,A.E. (2003) T cell-specific expression of the human TNF-alpha gene involves a functional and highly conserved chromatin signature in intron 3. J. Immunol., 171. 3612-3619.
-
(2003)
J. Immunol
, vol.171
, pp. 3612-3619
-
-
Barthel, R.1
Goldfeld, A.E.2
-
21
-
-
0033618307
-
Human tumor necrosis factor-alpha gene 3′ untranslated region confers inducible toxin responsiveness to homologous, promoter in monocytic THP-1 cells
-
Seiler-Tuyns,A., Dufour,N. and Spertini,F. (1999) Human tumor necrosis factor-alpha gene 3′ untranslated region confers inducible toxin responsiveness to homologous, promoter in monocytic THP-1 cells. J. Biol. Chem., 274, 21714-21718.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 21714-21718
-
-
Seiler-Tuyns, A.1
Dufour, N.2
Spertini, F.3
-
22
-
-
0025186678
-
Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages
-
Shakhov,A.N., Collart,M.A., Vassalli,P., Nedospas̀ov,S.A. and Jongeneel,C.V. (1990) Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J. Exp. Med., 171, 35-47.
-
(1990)
J. Exp. Med
, vol.171
, pp. 35-47
-
-
Shakhov, A.N.1
Collart, M.A.2
Vassalli, P.3
Nedospas̀ov, S.A.4
Jongeneel, C.V.5
-
23
-
-
0032516519
-
Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes
-
Udalova,I.A., Knight,J.C., Vidal,V., Nedospasov,S.A. and Kwiatkowski,D. (1998) Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes. J. Biol. Chem., 273 21178-21186.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 21178-21186
-
-
Udalova, I.A.1
Knight, J.C.2
Vidal, V.3
Nedospasov, S.A.4
Kwiatkowski, D.5
-
24
-
-
0028980260
-
Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: Distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages
-
Kuprash,D.V., Udalova,I.A., Turetskaya,R.L., Rice,N.R. and Nedospasov,S.A. (1995) Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: Distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages. Oncogene, 11, 97-106.
-
(1995)
Oncogene
, vol.11
, pp. 97-106
-
-
Kuprash, D.V.1
Udalova, I.A.2
Turetskaya, R.L.3
Rice, N.R.4
Nedospasov, S.A.5
-
25
-
-
0025519111
-
Tumor necrosis factor beta (TNF-beta) induces binding of the NF-kappa B transcription factor to a high-affinity kappa B element in the TNF-beta promoter
-
Messer,G., Weiss,E.H. and Baeuerle,P.A. (1990) Tumor necrosis factor beta (TNF-beta) induces binding of the NF-kappa B transcription factor to a high-affinity kappa B element in the TNF-beta promoter. Cytokine 2, 389-397.
-
(1990)
Cytokine
, vol.2
, pp. 389-397
-
-
Messer, G.1
Weiss, E.H.2
Baeuerle, P.A.3
-
26
-
-
0025131888
-
Lymphotoxin activation by human T-cell leukemia virus type I-infected cell lines: Role for NF-kappa B
-
Paul,N.L., Lenardo,M.J., Novak,K.D., Sarr,T., Tang,W.L. and Ruddle,N.H. (1990) Lymphotoxin activation by human T-cell leukemia virus type I-infected cell lines: Role for NF-kappa B. J. Virol., 64, 5412-5419.
-
(1990)
J. Virol
, vol.64
, pp. 5412-5419
-
-
Paul, N.L.1
Lenardo, M.J.2
Novak, K.D.3
Sarr, T.4
Tang, W.L.5
Ruddle, N.H.6
-
27
-
-
0026570260
-
A poly(dA-dT) upstream activating sequence binds high-mobility group 1 protein and contributes to lymphotoxin (tumor necrosis factor-beta) gene regulation
-
Fashena,S.J., Reeves,R. and Ruddle,N.H. (1992) A poly(dA-dT) upstream activating sequence binds high-mobility group 1 protein and contributes to lymphotoxin (tumor necrosis factor-beta) gene regulation. Mol. Cell Biol., 12, 894-903.
-
(1992)
Mol. Cell Biol
, vol.12
, pp. 894-903
-
-
Fashena, S.J.1
Reeves, R.2
Ruddle, N.H.3
-
28
-
-
0036720395
-
Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells
-
Kuprash,D.V., Boitchenko,V.E., Yarovinsky,F.O., Rice,N.R., Nordheim,A., Ruhlmann,A. and Nedospasov,S.A. (2002) Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells. Blood, 100, 1721-1727.
-
(2002)
Blood
, vol.100
, pp. 1721-1727
-
-
Kuprash, D.V.1
Boitchenko, V.E.2
Yarovinsky, F.O.3
Rice, N.R.4
Nordheim, A.5
Ruhlmann, A.6
Nedospasov, S.A.7
-
29
-
-
0031881907
-
CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells
-
Worm,M.M., Tsytsykova,A. and Geha,R.S. (1998) CD40 ligation and IL-4 use different mechanisms of transcriptional activation of the human lymphotoxin alpha promoter in B cells. Eur. J. Immunol., 28, 901-906.
-
(1998)
Eur. J. Immunol
, vol.28
, pp. 901-906
-
-
Worm, M.M.1
Tsytsykova, A.2
Geha, R.S.3
-
30
-
-
0029923540
-
Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation
-
Kuprash,D.V., Osipovich,O.A., Pokholok,D.K., Alimzhanov,M.B., Biragyb,A., Turetskaya,R.L. and Nedospasov,S.A. (1996) Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation. J Immunol., 156, 2465-2472.
-
(1996)
J Immunol
, vol.156
, pp. 2465-2472
-
-
Kuprash, D.V.1
Osipovich, O.A.2
Pokholok, D.K.3
Alimzhanov, M.B.4
Biragyb, A.5
Turetskaya, R.L.6
Nedospasov, S.A.7
-
31
-
-
1642290927
-
TNF and phorbol esters induce lymphotoxin-beta expression through distinct pathways involving Ets and NF-kappa B family members
-
Voon,D.C., Subrata,L.S., Karimi,M., Ulgiati,D. and Abraham,L.J. (2004) TNF and phorbol esters induce lymphotoxin-beta expression through distinct pathways involving Ets and NF-kappa B family members.J. Immunol., 172, 4332-4341.
-
(2004)
J. Immunol
, vol.172
, pp. 4332-4341
-
-
Voon, D.C.1
Subrata, L.S.2
Karimi, M.3
Ulgiati, D.4
Abraham, L.J.5
-
32
-
-
18744407845
-
Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
-
Ozaki,K., Ohnishi,Y., Iida,A., Sekine,A., Yamada,R., Tsunoda,T., Sato,H., Hori,M., Nakamura,Y. and Tanaka,T. (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat. Genet., 32, 650-654.
-
(2002)
Nat. Genet
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
Sekine, A.4
Yamada, R.5
Tsunoda, T.6
Sato, H.7
Hori, M.8
Nakamura, Y.9
Tanaka, T.10
-
33
-
-
0035251794
-
A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region
-
Ota,M., Katsuyama,Y., Kimura,A., Tsuchiya,K., Kondo,M., Naruse,T., Mizuki,N., Itoh,K., Sasazuki,T. and Inoko,H. (2001) A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region. Genomics, 71, 263-270.
-
(2001)
Genomics
, vol.71
, pp. 263-270
-
-
Ota, M.1
Katsuyama, Y.2
Kimura, A.3
Tsuchiya, K.4
Kondo, M.5
Naruse, T.6
Mizuki, N.7
Itoh, K.8
Sasazuki, T.9
Inoko, H.10
-
34
-
-
0028169333
-
Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria
-
McGuire,W., Hill,A.V., Allsopp,C.E., Greenwood,B.M. and Kwiatkowski,D. (1994) Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature, 371, 508-510.
-
(1994)
Nature
, vol.371
, pp. 508-510
-
-
McGuire, W.1
Hill, A.V.2
Allsopp, C.E.3
Greenwood, B.M.4
Kwiatkowski, D.5
-
35
-
-
34047143696
-
Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy
-
Alcais,A., Alter,A., Antoni,G., Orlova,M., Nguyen,V.T., Singh,M., Vanderborght,P.R., Katoch,K., Mira,M.T., Vu,H.T. et al. (2007) Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. Nat. Genet., 39 517-522.
-
(2007)
Nat. Genet
, vol.39
, pp. 517-522
-
-
Alcais, A.1
Alter, A.2
Antoni, G.3
Orlova, M.4
Nguyen, V.T.5
Singh, M.6
Vanderborght, P.R.7
Katoch, K.8
Mira, M.T.9
Vu, H.T.10
-
36
-
-
0023916712
-
Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes
-
Sariban,E., Imamura,K., Luebbers,R. and Kufe,D. (1988) Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes. J. Clin. Invest., 81, 1506-1510.
-
(1988)
J. Clin. Invest
, vol.81
, pp. 1506-1510
-
-
Sariban, E.1
Imamura, K.2
Luebbers, R.3
Kufe, D.4
-
37
-
-
0025946885
-
-
Sung.S.J., Walters,J.A., Hudson,J. and Gimble,J.M. (1991) Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization. J. Immunol., 147, 2047-2054.
-
Sung.S.J., Walters,J.A., Hudson,J. and Gimble,J.M. (1991) Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization. J. Immunol., 147, 2047-2054.
-
-
-
-
38
-
-
0029801756
-
Transcriptional and translational control of TNF-alpha gene expression in human monocytes by major histocompatibility complex class II ligands
-
Espel,E., Garcia-Sanz,J.A., Aubert,V., Menoud,V., Sperisen,P., Fernandez,N. and Spertini,F. (1996) Transcriptional and translational control of TNF-alpha gene expression in human monocytes by major histocompatibility complex class II ligands. Eur. J. Immunol., 26, 2417-2424.
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 2417-2424
-
-
Espel, E.1
Garcia-Sanz, J.A.2
Aubert, V.3
Menoud, V.4
Sperisen, P.5
Fernandez, N.6
Spertini, F.7
-
39
-
-
33750827600
-
Allele-specific chromatin remodeling of the tumor necrosis factor-alpha promoter
-
Skoog,T., Hamsten,A. and Eriksson,P. (2006) Allele-specific chromatin remodeling of the tumor necrosis factor-alpha promoter. Biochem. Biophys. Res. Commun., 351, 777-783.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.351
, pp. 777-783
-
-
Skoog, T.1
Hamsten, A.2
Eriksson, P.3
-
40
-
-
33646069367
-
Transactivator of transcription from HIV type 1 subtype E selectively inhibits TNF gene expression via interference with chromatin remodeling of the TNF locus
-
Ranjbar,S., Rajsbaum,R. and Goldfeld,A.E. (2006) Transactivator of transcription from HIV type 1 subtype E selectively inhibits TNF gene expression via interference with chromatin remodeling of the TNF locus. J. Immunol., 176, 4182-4190.
-
(2006)
J. Immunol
, vol.176
, pp. 4182-4190
-
-
Ranjbar, S.1
Rajsbaum, R.2
Goldfeld, A.E.3
-
41
-
-
0026516441
-
Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locus
-
Kuhnert,P., Peterhans,E. and Pauli,U. (1992) Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locus. Nucleic Acids Res., 20, 1943-1948.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 1943-1948
-
-
Kuhnert, P.1
Peterhans, E.2
Pauli, U.3
-
42
-
-
36749019654
-
Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers
-
Tsytsykova,A.V., Rajsbaum,R., Falvo,J.V., Ligeiro,F., Neely,S.R. and Goldfeld,A.E. (2007) Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers. Proc. Natl. Acad. Sci. USA, 104, 16850-16855.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16850-16855
-
-
Tsytsykova, A.V.1
Rajsbaum, R.2
Falvo, J.V.3
Ligeiro, F.4
Neely, S.R.5
Goldfeld, A.E.6
-
43
-
-
0031638053
-
Chromatin organization in the tumor necrosis factor/lymphotoxin gene locus: Correlation with tissue-specific expression
-
Tumanov,A.V., Nedospasov,S.A. and Turetskaia,R.L. (1998) Chromatin organization in the tumor necrosis factor/lymphotoxin gene locus: correlation with tissue-specific expression. Mol. Biol. (Mosk), 32, 98-102.
-
(1998)
Mol. Biol. (Mosk)
, vol.32
, pp. 98-102
-
-
Tumanov, A.V.1
Nedospasov, S.A.2
Turetskaia, R.L.3
-
44
-
-
0033990048
-
-
Krawetz,S. and Misener,S, eds, Humana Press, Totowa. NJ, pp
-
Rozen,S. and Skaletsky,H.J. (2000) In Krawetz,S. and Misener,S. (eds), Bioinformatics Methods and Protocols: Methods in Molecular Biology. Humana Press, Totowa. NJ, pp. 365-386.
-
(2000)
Bioinformatics Methods and Protocols: Methods in Molecular Biology
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.J.2
-
45
-
-
0037435395
-
Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
-
Rumakers,C., Ruijter,J.M., Deprez,R.H. and Moorman,A.F. (2003) Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci. Lett., 339, 62-66.
-
(2003)
Neurosci. Lett
, vol.339
, pp. 62-66
-
-
Rumakers, C.1
Ruijter, J.M.2
Deprez, R.H.3
Moorman, A.F.4
-
46
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak,K.J. and Schmittgen,T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
47
-
-
0034175616
-
Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression
-
Takahashi,Y., Rayman,J.B. and Dynlacht,B.D. (2000) Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression. Genes Dev., 14, 804-816.
-
(2000)
Genes Dev
, vol.14
, pp. 804-816
-
-
Takahashi, Y.1
Rayman, J.B.2
Dynlacht, B.D.3
-
48
-
-
33744475085
-
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter
-
De Gobbi,M., Viprakasit,V., Hughes,J.R., Fisher,C., Buckle,V.J., Ayyub,H., Gibbons,R.J., Vernimmen,D., Yoshinaga,Y., de Jong,P. et al. (2006) A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science, 312, 1215-1217.
-
(2006)
Science
, vol.312
, pp. 1215-1217
-
-
De Gobbi, M.1
Viprakasit, V.2
Hughes, J.R.3
Fisher, C.4
Buckle, V.J.5
Ayyub, H.6
Gibbons, R.J.7
Vernimmen, D.8
Yoshinaga, Y.9
de Jong, P.10
-
49
-
-
3042569525
-
Complete MHC haplotype sequencing for common disease gene mapping
-
Stewart,C.A., Horton,R., Allcock,R.J., Ashurst,J.L., Atrazhev,A.M., Coggill,P., Dunham,I., Forbes,S., Halls,K., Howson,J.M. et al. (2004) Complete MHC haplotype sequencing for common disease gene mapping. Genome Res., 14, 1176-1187.
-
(2004)
Genome Res
, vol.14
, pp. 1176-1187
-
-
Stewart, C.A.1
Horton, R.2
Allcock, R.J.3
Ashurst, J.L.4
Atrazhev, A.M.5
Coggill, P.6
Dunham, I.7
Forbes, S.8
Halls, K.9
Howson, J.M.10
-
50
-
-
0032993434
-
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
-
Knight,J.C., Udalova,I., Hill,A.V, Greenwood,B.M., Peshu,N., Marsh,K. and Kwiatkowski,D. (1999) A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat. Genet., 22, 145-150.
-
(1999)
Nat. Genet
, vol.22
, pp. 145-150
-
-
Knight, J.C.1
Udalova, I.2
Hill, A.V.3
Greenwood, B.M.4
Peshu, N.5
Marsh, K.6
Kwiatkowski, D.7
-
51
-
-
0028339905
-
Solid phase DNase I footprinting: Quick and versatile
-
Sandaltzopoulos,R. and Becker,P.B. (1994) Solid phase DNase I footprinting: Quick and versatile. Nucleic Acids Res., 22, 1511-1512.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1511-1512
-
-
Sandaltzopoulos, R.1
Becker, P.B.2
-
52
-
-
0024380087
-
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
-
Schreiber,E., Matthias,P., Muller,M.M. and Schaffner,W. (1989) Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res., 17, 6419.
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 6419
-
-
Schreiber, E.1
Matthias, P.2
Muller, M.M.3
Schaffner, W.4
-
53
-
-
0026747665
-
Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin
-
Vyas,P., Vickers,M.A., Simmons,D.L., Ayyub,H., Craddock,C.F. and Higgs,D.R. (1992) Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin. Cell, 69, 781-793.
-
(1992)
Cell
, vol.69
, pp. 781-793
-
-
Vyas, P.1
Vickers, M.A.2
Simmons, D.L.3
Ayyub, H.4
Craddock, C.F.5
Higgs, D.R.6
-
54
-
-
33847277297
-
Enhancer identification through comparative genomics
-
Visel,A., Bristow,J. and Pennacchio,L.A. (2007) Enhancer identification through comparative genomics. Semin. Cell Dev. Biol., 18, 140-152.
-
(2007)
Semin. Cell Dev. Biol
, vol.18
, pp. 140-152
-
-
Visel, A.1
Bristow, J.2
Pennacchio, L.A.3
-
55
-
-
23744458086
-
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
-
Siepel,A., Bejerano,G., Pedersen,J.S., Hinrichs,A.S., Hou,M., Rosenbloom,K., Clawson,H., Spieth,J., Hillier,L.W., Richards,S. et al. (2005) Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res., 15, 1034-1050.
-
(2005)
Genome Res
, vol.15
, pp. 1034-1050
-
-
Siepel, A.1
Bejerano, G.2
Pedersen, J.S.3
Hinrichs, A.S.4
Hou, M.5
Rosenbloom, K.6
Clawson, H.7
Spieth, J.8
Hillier, L.W.9
Richards, S.10
-
56
-
-
33845303175
-
ESPERR: Learning strong and weak signals genomic sequence alignment to identify functional elements
-
Taylor,J., Tyekucheva,S., King,D.C., Hardison,R.C., Miller,W. and Chiaromonte,F. (2006) ESPERR: Learning strong and weak signals genomic sequence alignment to identify functional elements. Genome Res., 16, 1596-1604.
-
(2006)
Genome Res
, vol.16
, pp. 1596-1604
-
-
Taylor, J.1
Tyekucheva, S.2
King, D.C.3
Hardison, R.C.4
Miller, W.5
Chiaromonte, F.6
-
57
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides,T. (2007) Chromatin modifications and their function. Cell 128, 693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
58
-
-
0004049440
-
-
Beutler,B, ed, Raven Press Ltd, New York, pp
-
Jongeneel,C.V. (1992) In Beutler,B. (ed.), Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. Raven Press Ltd, New York, pp. 539-559.
-
(1992)
Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine
, pp. 539-559
-
-
Jongeneel, C.V.1
-
59
-
-
0039076954
-
-
Fiers,W. and Buurman,W.A, eds, Karger, Basel, pp
-
Kuprash,D., Turetskaya,R., Boldin,M., Udalova,I., Kistanova,E., Smirnova,J. and Nedospasov,S. (1993) In Fiers,W. and Buurman,W.A. (eds), Tumour Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance. Karger, Basel, pp. 19-26.
-
(1993)
Tumour Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance
, pp. 19-26
-
-
Kuprash, D.1
Turetskaya, R.2
Boldin, M.3
Udalova, I.4
Kistanova, E.5
Smirnova, J.6
Nedospasov, S.7
-
60
-
-
25444433340
-
Upstream stimulating factors: Highly versatile stress-responsive transcription factors
-
Corre,S. and Galibert,M.D. (2005) Upstream stimulating factors: Highly versatile stress-responsive transcription factors. Pigment Cell Res. 18, 337-348.
-
(2005)
Pigment Cell Res
, vol.18
, pp. 337-348
-
-
Corre, S.1
Galibert, M.D.2
-
61
-
-
0027371952
-
The helix-loop-helix transcription factor USF (upstream stimulating factor) binds to a regulatory sequence of the human insulin gene enhancer
-
Read,M.L., Clark,A.R. and Docherty,K. (1993) The helix-loop-helix transcription factor USF (upstream stimulating factor) binds to a regulatory sequence of the human insulin gene enhancer. Biochem J, 295 (Pt 1), 233-237.
-
(1993)
Biochem J
, vol.295
, Issue.PART 1
, pp. 233-237
-
-
Read, M.L.1
Clark, A.R.2
Docherty, K.3
-
62
-
-
0033596120
-
Regulation of DNA binding by Rel/NF-kappaB transcription factors: Structural views
-
Chen,F.E. and Ghosh,G. (1999) Regulation of DNA binding by Rel/NF-kappaB transcription factors: Structural views. Oncogene, 18, 6845-6852.
-
(1999)
Oncogene
, vol.18
, pp. 6845-6852
-
-
Chen, F.E.1
Ghosh, G.2
-
63
-
-
0032556894
-
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
-
Chen,F.E., Huang,D.B., Chen,Y.Q. and Ghosh,G. (1998) Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature, 391, 410-413.
-
(1998)
Nature
, vol.391
, pp. 410-413
-
-
Chen, F.E.1
Huang, D.B.2
Chen, Y.Q.3
Ghosh, G.4
-
64
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
Macian,F. (2005) NFAT proteins: Key regulators of T-cell development and function. Nat. Rev. Immunol., 5, 472-484.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
65
-
-
8644220507
-
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3
-
Lee,D.U. and Rao,A. (2004) Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3. Proc. Natl. Acad. Sci. USA, 101, 16010-16015.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16010-16015
-
-
Lee, D.U.1
Rao, A.2
-
66
-
-
27744584107
-
Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells
-
Monticelli,S., Lee,D.U., Nardone,J., Bolton,D.L. and Rao,A. (2005) Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells. Int. Immunol., 17, 1513-1524.
-
(2005)
Int. Immunol
, vol.17
, pp. 1513-1524
-
-
Monticelli, S.1
Lee, D.U.2
Nardone, J.3
Bolton, D.L.4
Rao, A.5
-
67
-
-
0025607864
-
Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide
-
Goldfeld,A.E., Doyle,C. and Maniatis,T. (1990) Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. Proc. Natl. Acad. Sci. USA, 87, 9769-9773.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 9769-9773
-
-
Goldfeld, A.E.1
Doyle, C.2
Maniatis, T.3
-
68
-
-
0348013068
-
Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse
-
Xie,T., Rowen,L., Aguado,B., Ahearn,M.E., Madan,A., Qin,S., Campbell,R.D. and Hood,L. (2003) Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. Genome Res., 13, 2621-2636.
-
(2003)
Genome Res
, vol.13
, pp. 2621-2636
-
-
Xie, T.1
Rowen, L.2
Aguado, B.3
Ahearn, M.E.4
Madan, A.5
Qin, S.6
Campbell, R.D.7
Hood, L.8
-
69
-
-
0033120071
-
Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide
-
Kuprash,D.V., Udalova,I.A., Turetskaya,R.L., Kwiatkowski,D., Rice,N.R, and Nedospasov,S.A. (1999) Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. J. Immunol., 162, 4045-4052.
-
(1999)
J. Immunol
, vol.162
, pp. 4045-4052
-
-
Kuprash, D.V.1
Udalova, I.A.2
Turetskaya, R.L.3
Kwiatkowski, D.4
Rice, N.R.5
Nedospasov, S.A.6
-
70
-
-
0028274641
-
Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins
-
Albertella,M.R. and Campbell,R.D. (1994) Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins. Hum. Mol. Genet., 3, 793-799.
-
(1994)
Hum. Mol. Genet
, vol.3
, pp. 793-799
-
-
Albertella, M.R.1
Campbell, R.D.2
-
71
-
-
0036471943
-
A distinct bipartite motif is required for the localization of inhibitory kappaB-like (IkappaBL) protein to nuclear speckles
-
Semple,J.I., Brown,S.E., Sanderson,C.M. and Campbell,R.D. (2002) A distinct bipartite motif is required for the localization of inhibitory kappaB-like (IkappaBL) protein to nuclear speckles. Biochem. J., 361, 489-496.
-
(2002)
Biochem. J
, vol.361
, pp. 489-496
-
-
Semple, J.I.1
Brown, S.E.2
Sanderson, C.M.3
Campbell, R.D.4
-
72
-
-
0037318784
-
Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis
-
Okamoto,K., Makino,S., Yoshikawa,Y., Takaki,A., Nagatsuka,Y., Ota,M., Tamiya,G., Kimura,A., Bahram,S. and Inoko,H. (2003) Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Am. J. Hum. Genet., 72, 303-312.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 303-312
-
-
Okamoto, K.1
Makino, S.2
Yoshikawa, Y.3
Takaki, A.4
Nagatsuka, Y.5
Ota, M.6
Tamiya, G.7
Kimura, A.8
Bahram, S.9
Inoko, H.10
-
73
-
-
0033047079
-
The central MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3,B7,DR15
-
Allcock,R.J., Christiansen,F.T. and Price,P. (1999) The central MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3,B7,DR15. Immunogenetics, 49, 660-665.
-
(1999)
Immunogenetics
, vol.49
, pp. 660-665
-
-
Allcock, R.J.1
Christiansen, F.T.2
Price, P.3
|