Identification and characterization of the catalytic subunit of phosphatidylinositol 3-kinase in the yellow fever mosquito Aedes aegypti

Insect Biochemistry and Molecular Biology

Volumn 38, Issue 10, 2008, Pages 932-939

  Pri Tal, Benjamin M ^a   Brown, Jessica M ^b   Riehle, Michael A ^b  

^a PORTLAND STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Aaegp110; Insulin; Insulin signaling; PI(3,4,5)P3; PI3K; PTEN

Indexed keywords

INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE;

AEDES; ANIMAL; ARTICLE; ENZYME ACTIVE SITE; ENZYMOLOGY; FEMALE; GENE EXPRESSION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; OVARY; OVIPARITY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AEDES; ANIMALS; CATALYTIC DOMAIN; FEMALE; GENE EXPRESSION; INSULIN; OVARY; OVIPARITY; SIGNAL TRANSDUCTION;

AEDES AEGYPTI; BOVINAE;

EID: 50849108835     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2008.07.004     Document Type: Article

References (56)

1. Babar P., Adamson C., Walker G.A., Walker D.W., and Lithgow G.J. P13-kinase inhibition induces dauer formation, thermotolerance and longevity in C. elegans. Neurobiol. Aging 20 (1999) 513-519
2. Barbieri M., Bonafe M., Franceschi C., and Paolisso G. Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am. J. Physiol. Endocrinol. Metab. 285 (2003) 1064-1071
3. Barnes A.I., and Partridge L. Costing reproduction. Anim. Behav. 66 (2003) 199-204
4. Braeckman B.P., Houthoofd K., and Vanfleteren J.R. Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans. Mech. Ageing Dev. 122 (2001) 673-693
5. Brown M.R., Graf R., Swiderek K.M., Fendley D., Stracker T.H., Champagne D.E., and Lea A.O. Identification of a steroidogenic neurohormone in female mosquitoes. J. Biol. Chem. 273 (1998) 3967-3971
6. Brown M.R., Clark K.D., Gulia M., Zhao Z., Garczynski S.F., Crim J.W., Suderman R.J., and Strand M.R. An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 5716-5721
7. Broughton S.J., Piper M.D., Ikeya T., Bass T.M., Jacobson J., Driege Y., Martinez P., Hafen E., Withers D.J., Leevers S.J., and Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 3105-3110
8. Clancy D.J., Gems D., Harshman L.G., Oldham S., Stocker H., Hafen E., Leevers S.J., and Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292 (2001) 104-106
9. de Jong G. Covariance between traits deriving from successive allocations of a resource. Funct. Ecol. 7 (1993) 75-83
10. Dillin A., Crawford D.K., and Kenyon C. Timing requirements for insulin/IGF-1 signaling in C. elegans. Science 298 (2002) 830-834
11. Dimopoulos G., Richman A., della Torre A., Kafatos F.C., and Louis C. Identification and characterization of differentially expressed cDNAs of the vector mosquito, Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13066-13071
12. Fernandez R., Tabarini D., Azpiazu N., Frasch M., and Schlessinger J. The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. EMBO J. 14 (1995) 3373-3384
13. Foster F.M., Traer C.J., Abraham S.M., and Fry M.J. The phosphoinositide (PI) 3-kinase family. J. Cell Sci. 116 (2003) 3037-3040
14. Friedman D.B., and Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118 (1988) 75-86
15. Fry M.J. Structure, regulation and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1226 (1994) 237-268
16. Fry M.J., Panayotou G., Dhand R., Ruiz-Larrea F., Gout I., Nguyen O., Courtneidge S.A., and Waterfield M.D. Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns. Biochem. J. 288 Pt 2 (1992) 383-393
17. Garofalo R.S. Genetic analysis of insulin signaling in Drosophila. Trends Endocrinol. Metab. 13 (2002) 156-162
18. Geering B., Cutillas P.R., Nock G., Gharbi S.I., and Vanhaesebroeck B. Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 7809-7814
19. Gems D., and McElwee J.J. Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?. Mech. Ageing Dev. 126 (2005) 381-387
20. Gems D., Sutton A.J., Sundermeyer M.L., Albert P.S., King K.V., Edgley M.L., Larsen P.L., and Riddle D.L. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150 (1998) 129-155
21. Giannakou M.E., Goss M., Junger M.A., Hafen E., Leevers S.J., and Partridge L. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 305 (2004) 361
22. Hirsch E., Costa C., and Ciraolo E. Phosphoinositide 3-kinases as a common platform for multi-hormone signaling. J. Endocrinol. 194 (2007) 243-256
23. Houthoofd K., Fidalgo M.A., Hoogewijs D., Braeckman B.P., Lenaerts I., Brys K., Matthijssens F., De Vreese A., Van Eygen S., Munoz M.J., and Vanfleteren J.R. Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans. Aging Cell 4 (2005) 87-95
24. Hsin H., and Kenyon C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399 (1999) 362-366
25. Hsu A.L., Murphy C.T., and Kenyon C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300 (2003) 1142-1145
26. Huang C.H., Mandelker D., Schmidt-Kittler O., Samuels Y., Velculescu V.E., Kinzler K.W., Vogelstein B., Gabelli S.B., and Amzel L.M. The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science 318 (2007) 1744-1748
27. Hwangbo D.S., Gershman B., Tu M.P., Palmer M., and Tatar M. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429 (2004) 562-566
28. Kang M.A., Mott T.M., Tapley E.C., Lewis E.E., and Luckhart S. Insulin regulates aging and oxidative stress in Anopheles stephensi. J. Exp. Biol. 211 (2008) 741-748
29. Katso R., Okkenhaug K., Ahmadi K., White S., Timms J., and Waterfield M.D. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 17 (2001) 615-675
30. Kazlauskas A., and Cooper J.A. Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase. EMBO J. 9 (1990) 3279-3286
31. Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
32. Kirkwood T.B., and Holliday R. The evolution of ageing and longevity. Proc. R. Soc. Lond. B Biol. Sci. 205 (1979) 531-546
33. Krieger M.J., Jahan N., Riehle M.A., Cao C., and Brown M.R. Molecular characterization of insulin-like peptide genes and their expression in the African malaria mosquito, Anopheles gambiae. Insect Mol. Biol. 13 (2004) 305-315
34. Leevers S.J., Weinkove D., MacDougall L.K., Hafen E., and Waterfield M.D. The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J. 15 (1996) 6584-6594
35. Lin K., Hsin H., Libina N., and Kenyon C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat. Genet. 28 (2001) 139-145
36. Muller F.L., Lustgarten M.S., Jang Y., Richardson A., and Van Remmen H. Trends in oxidative aging theories. Free. Radic. Biol. Med. 43 (2007) 477-503
37. Ogg S., Paradis S., Gottlieb S., Patterson G.I., Lee L., Tissenbaum H.A., and Ruvkun G. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389 (1997) 994-999
38. Orme M.H., Alrubaie S., Bradley G.L., Walker C.D., and Leevers S.J. Input from Ras is required for maximal PI(3)K signalling in Drosophila. Nat. Cell Biol. 8 (2006) 1298-1302
39. Partridge L., Gems D., and Withers D.J. Sex and death: what is the connection?. Cell 120 (2005) 461-472
40. Petruzzelli L., Herrera R., Garcia-Arenas R., and Rosen O.M. Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis. J. Biol. Chem. 260 (1985) 16072-16075
41. Riehle M.A., and Brown M.R. Insulin stimulates ecdysteroid production through a conserved signaling cascade in the mosquito Aedes aegypti. Insect Biochem. Mol. Biol. 29 (1999) 855-860
42. Riehle M.A., and Brown M.R. Insulin receptor expression during development and a reproductive cycle in the ovary of the mosquito Aedes aegypti. Cell Tissue Res. 308 (2002) 409-420
43. Riehle M.A., and Brown M.R. Molecular analysis of the serine/threonine kinase Akt and its expression in the mosquito Aedes aegypti. Insect Mol. Biol. 12 (2003) 225-232
44. Riehle M.A., and Brown J.M. Characterization of Phosphatase and Tensin Homolog expression in the mosquito Aedes aegypti: six splice variants with developmental and tissue specificity. Insect Mol. Biol. 16 (2007) 277-286
45. Riehle M.A., Garczynski S.F., Crim J.W., Hill C.A., and Brown M.R. Neuropeptides and peptide hormones in Anopheles gambiae. Science 298 (2002) 172-175
46. Riehle M.A., Fan Y., Cao C., and Brown M.R. Molecular characterization of insulin-like peptides in the yellow fever mosquito, Aedes aegypti: expression, cellular localization, and phylogeny. Peptides 27 (2006) 2547-2560
47. Roy S.G., Hansen I.A., and Raikhel A.S. Effect of insulin and 20-hydroxyecdysone in the fat body of the yellow fever mosquito, Aedes aegypti. Insect Biochem. Mol. Biol. 37 (2007) 1317-1326
48. Shingleton A.W., Das J., Vinicius L., and Stern D.L. The temporal requirements for insulin signaling during development in Drosophila. PLoS Biol. 3 (2005) e289
49. Tatar M., Kopelman A., Epstein D., Tu M.P., Yin C.M., and Garofalo R.S. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 292 (2001) 107-110
50. Tissenbaum H.A., and Ruvkun G. An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. Genetics 148 (1998) 703-717
51. van Noordwijk A.J., and de Jong G. Acquisition and allocation of resources: their influence on variation in life history tactics. Am. Nat. 128 (1986) 137-142
52. Weinkove D., Neufeld T.P., Twardzik T., Waterfield M.D., and Leevers S.J. Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr. Biol. 9 (1999) 1019-1029
53. Williams G.C. Natural selection, the cost of reproduction, and a refinement of Lack's principle. Am. Nat. 100 (1966) 687-690
54. Wolff S., and Dillin A. The trifecta of aging in Caenorhabditis elegans. Exp. Gerontol. 41 (2006) 894-903
55. Wolkow C.A., Kimura K.D., Lee M.S., and Ruvkun G. Regulation of C. elegans life-span by insulin-like signaling in the nervous system. Science 290 (2000) 147-150
56. Yang Y., Gehrke S., Haque M.E., Imai Y., Kosek J., Yang L., Beal M.F., Nishimura I., Wakamatsu K., Ito S., Takahashi R., and Lu B. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 13670-13675