Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b

Biochemistry

Volumn 43, Issue 30, 2004, Pages 9725-9731

  Yowler, Brian C ^a   Schengrund, Cara Lynne ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONFORMATIONS; DISSOCIATION; IONIC STRENGTH; PHOSPHOLIPIDS; RATE CONSTANTS; SURFACE PLASMON RESONANCE; TOXIC MATERIALS;

GANGLIOSIDES; NEUROTOXINS;

BIOCHEMISTRY;

BOTULINUM TOXIN A; BUFFER; GANGLIOSIDE; GANGLIOSIDE GT 1B; NEUROTOXIN; PHOSPHOLIPID; POLYSIALYLATED GANGLIOSIDE; SODIUM CHLORIDE; TROMETAMOL; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; BINDING KINETICS; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DATA ANALYSIS; DISSOCIATION; IONIC STRENGTH; KINETICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; SURFACE PLASMON RESONANCE;

BOTULINUM TOXIN TYPE A; BUFFERS; CIRCULAR DICHROISM; DIMYRISTOYLPHOSPHATIDYLCHOLINE; GANGLIOSIDES; KINETICS; LIPOSOMES; OSMOLAR CONCENTRATION; PROTEIN BINDING; PROTEIN CONFORMATION; SODIUM CHLORIDE; SURFACE PLASMON RESONANCE; TROMETHAMINE;

EID: 3342901819     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0494673     Document Type: Article

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