Maturation-induces endothelial dysfunction via vascular inflammation in diabetic mice

Basic Research in Cardiology

Volumn 103, Issue 5, 2008, Pages 407-416

  Zhang, Cuihua ^a,b   Park, Yoonjung ^b   Picchi, Andrea ^b   Potter, Barry J ^c  

^a University of Missouri   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coronary microcirculation; Cytokines; Endothelialdys function; Inflammation

Indexed keywords

ACETYLCHOLINE; APOCYNIN; GLUCOSE; INSULIN; LIPID; N(G) METHYLARGININE; NEUTRALIZING ANTIBODY; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTICLE; BLOOD FLOW; BLOOD LEVEL; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENDOTHELIAL DYSFUNCTION; FEMALE; HYPOTHESIS; MALE; MATURATION; MITOCHONDRIAL RESPIRATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN; VASCULITIS; VASODILATATION;

ABDOMEN; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE MODELS, ANIMAL; FEMALE; INSULIN RESISTANCE; LIPIDS; MALE; MICE; MICE, INBRED C57BL; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VASCULITIS;

EID: 50249138173     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-008-0725-0     Document Type: Article

References (25)

1. Böse D, Leineweber K, Konorza T, Zahn A, Bröcker-Preuss M, Mann K, Haude M, Erbel R, Heusch G (2007) Release of TNF-alpha during stent implantation into saphenous vein aortocoronary bypass grafts and its relation to plaque extrusion and restenosis. Am J Physiol Heart Circ Physiol 292:H2295-H2299
2. Csiszar A, Labinskyy N, Orosz Z, Ungvari Z (2006) Altered mitochondrial energy metabolism many play a role in vascular aging. Med Hypotheses 67:904-908
3. Elliott MJ, Maini RN, Feldman AM (1994) Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105-1110
4. Erbel C, Sato K, Meyer FB, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM (2007) Functional profile of activated dendritic cells in unstable atherosclerotic plaque. Basic Res Cardiol 102:123-132
5. Gao X, Belmadani S, Picchi A, Xu X, Potte BJ, Tewari-Singh N, Capobianco S, Chilian WM, Zhang C (2007) Tumor necrosis factor alpha-induces endothelial dysfunction in Leprdb mice. Circulation 115:245-254
6. Guzik TJ, Mussa S, Gastaldi D, Sadowsky J, Ratnatunga C, Pillai R, Channon KM (2002) Mechanisms of increased vascular superoxide production in humans diabetes mellitus. Role of NADPH oxidase and endothelial nitric oxide synthase. Circulation 105:1656-1662
7. Haffner SM, Lehto S, Ronnemaa T (1998) Mortality from coronary heart disease in subjects with type 2 diabetes and in non-diabetic subjects with and without prior myocardial infarction. N Engl J Med 339:229-234
8. Kadokami T, Frye CS, Lemster BH (2001) Anti-tumor necrosis factor-alpha antibody limits heart failure in a transgenic model. Circulation 104:1094-1097
9. Kuo L, Davis MJ, Chilian WM (1988) Myogenic activity in isolated subepicardial and subendocardial coronary arterioles. Am J Physiol 255:H1558-H1562
10. Lattime ECSO (1991) Thymic lymphomas mediate non-MHC-restricted, TNF-dependent lysis of the murine sarcoma WEHI-164. Cell Immunol 136:69-79
11. Livak KJ, Schmittgen TD (1991) Analysis of relative gene expression data using real-time quantitative PCR and the 2-δδCT method. Methods 25:402-408
12. Meldrum DM, Cleveland JC, Cain BS (1998) Increased myocardial tumor necrosis factor-α in a crystalloid-perfused model of cardiac ischemia-reperfusion injury. Ann Thorac Surg 65:439-443
13. Rask-Madsen C, Dominguez H, Ihlemann N (2003) Tumor-necrosis factor-α inhibits insulin's stimulating effect on glucose uptake and endothelium-dependent vasodilation in humans. Circ Res 203:1815-1821
14. Schmidt A, Geigenmüller S, Völker W, Buddecke E (2006) The antiatherogenic and antiinflammatory effect of HDL-associated lysosphingolipids operates via Akt -> NF-kappaB signalling pathways in human vascular endothelial cells. Basic Res Cardiol 101:109-116
15. Skyschally A, Gres P, Hoffmann S, Haude M, Erbel R, Schulz R, Heusch G (2007) Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: Progressive contractile dysfunction versus delayed protection against infarction. Circ Res 100:140-146
16. Soucy KG, Ryoo S, Benjo A, Lim HK, Gupta G, Sohi JS, Elser J, Aon MA, Nyhan D, Shoukas AA, Berkowitz DE (2006) Impaired shear stress-induced nitric oxide production through decreased NOS phosphorylation contributes to age-related vascular stiffness. J Appl Physiol 101:1751-1759
17. Sun D, Huang A, Yan EH, Wu Z, Yan C, Kaminski P, Oury TD, Wolin MS, Kaley G (2004) Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. Am J Physiol Heart Circ Physiol 286:H2249-H2256
18. Thielmann M, Dörge H, Martin C, Belosjorow S, Schwanke U, van De Sand A, Konietzka I, Büchert A, Krüger A, Schulz R, Heusch G (2002) Myocardial dysfunction with coronary microembolization: Signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine. Circ Res 90:807-813
19. Verges B (2004) Clinical interest of PPARs ligands. Diabetes Metab 30:7-12
20. Wallach D, Varfolomeev EE, Malinin NL (1999) Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol 17:331-367
21. Westermann D, Van Linthout S, Dhayat S, Dhayat N, Schmidt A, Noutsias M, Song XY, Spillmann F, Riad A, Schultheiss HP, Tschöpe C (2007) Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy. Basic Res Cardiol 102:500-507
22. Yudkin GS, Stehouwer CD, Emeis JJ (1999) C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 19:972-978
23. Zhang C, Hein TW, Wang W, Ren Y, Shipley RD, Kuo L (2006) Activation of JNK and xanthine oxidase by TNF-α impairs nitric oxide-mediated dilation of coronary arterioles. J Mol Cell Cardiol 40:47-257
24. Zhang C, Xu X, Potter BJ, Wang W, Kuo L, Michael L, Bagby GJ, Chilian WM (2006) TNF-alpha contributes to endothelial dysfunction in ischemia/ reperfusion injury. Arterioscler Thromb Vasc Biol 26:475-480
25. Zhang DX, Yi FX, Zou AP (2002) Role of ceramide in TNF-α-induced impairment of endothelium-dependent vasorelation in coronary arteries. Am J Physiol Heart Circ Physiol 283:H1758-H1794