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Volumn 15, Issue 3, 1999, Pages 288-295

Toward metabolic phenomics: Analysis of genomic data using flux balances

Author keywords

[No Author keywords available]

Indexed keywords

ANNOTATED GENOME; BIOENGINEERING; FLUX BALANCE ANALYSIS; GENOME ANALYSIS; METABOLIC ENGINEERING; SEQUENCE ANALYSIS;

EID: 0033136116     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp9900357     Document Type: Review
Times cited : (170)

References (47)
  • 2
    • 0030920780 scopus 로고    scopus 로고
    • Year of the genome
    • Ash, C. Year of the genome. Trends Microbiol. 1997, 5 (4), 135-139.
    • (1997) Trends Microbiol. , vol.5 , Issue.4 , pp. 135-139
    • Ash, C.1
  • 3
    • 0030768943 scopus 로고    scopus 로고
    • Laboratory workhorse decoded
    • Pennisi, E. Laboratory Workhorse Decoded Science 1997, 277, 1432-1434.
    • (1997) Science , vol.277 , pp. 1432-1434
    • Pennisi, E.1
  • 4
    • 0030909685 scopus 로고    scopus 로고
    • The future is function
    • Fields, S. The future is function. Nat. Genet. 1997, 15, 325-327.
    • (1997) Nat. Genet. , vol.15 , pp. 325-327
    • Fields, S.1
  • 5
    • 0030725715 scopus 로고    scopus 로고
    • Functional genomics: It's all how you read it
    • Hieter, P.; Boguski, M. Functional genomics: It's all how you read it. Science 1997, 278, 601-602.
    • (1997) Science , vol.278 , pp. 601-602
    • Hieter, P.1    Boguski, M.2
  • 6
    • 0030333694 scopus 로고    scopus 로고
    • Progress with proteome projects: Why all proteins expressed by a genome should be identified and how to do it
    • Wilkins, M. R.; et al. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it. Biotechnol. Genet. Eng. Rev. 1998, 13, 19-50.
    • (1998) Biotechnol. Genet. Eng. Rev. , vol.13 , pp. 19-50
    • Wilkins, M.R.1
  • 7
    • 0030971894 scopus 로고    scopus 로고
    • Microbial genomics: The floodgates open
    • Blaine Metting, F.; Romine, M. F. Microbial genomics: the floodgates open. Trends Microbiol. 1997, 5 (3), 91-92.
    • (1997) Trends Microbiol. , vol.5 , Issue.3 , pp. 91-92
    • Blaine Metting, F.1    Romine, M.F.2
  • 8
    • 0030980503 scopus 로고    scopus 로고
    • Microbial genomics: Milestones mount exponentially
    • Fox, J. L. Microbial genomics: Milestones mount exponentially. Nat. Biotechnol. 1997,15, 211-212.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 211-212
    • Fox, J.L.1
  • 9
    • 0031092897 scopus 로고    scopus 로고
    • The coming Kuhnian revolution in biology
    • Strothman, R. C. The Coming Kuhnian Revolution in Biology. Nat. Biotechnol. 1997, 15, 194-199.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 194-199
    • Strothman, R.C.1
  • 10
    • 0030641668 scopus 로고    scopus 로고
    • What lies beyond bioinformatics?
    • Palsson, B. O. What lies beyond bioinformatics? Nat Biotechnol. 1997, 15, 3-4.
    • (1997) Nat Biotechnol. , vol.15 , pp. 3-4
    • Palsson, B.O.1
  • 11
    • 0030219788 scopus 로고    scopus 로고
    • Computational comparisons of model genomes
    • Ouzounis, C.; Casari, G. Computational comparisons of model genomes. Trends Biotechnol. 1996, 14 (August), 280-285.
    • (1996) Trends Biotechnol. , vol.14 , Issue.AUGUST , pp. 280-285
    • Ouzounis, C.1    Casari, G.2
  • 15
    • 0028108519 scopus 로고
    • Metabolic flux balancing: Basic concepts, scientific and practical use
    • Varma, A.; Palsson, B. O. Metabolic Flux Balancing: Basic concepts, Scientific and Practical Use. Biotechnol. Bioeng. 1994, 12, 994-998.
    • (1994) Biotechnol. Bioeng. , vol.12 , pp. 994-998
    • Varma, A.1    Palsson, B.O.2
  • 16
    • 0030804853 scopus 로고    scopus 로고
    • Flux analysis of underdetermined metabolic networks: The quest for the missing constraints
    • Bonarius, H. P. J.; Schmid, G.; Tramper, J. Flux analysis of underdetermined metabolic networks: the quest for the missing constraints. Trends Biotechnol. 1997, 15 (August), 308-314.
    • (1997) Trends Biotechnol. , vol.15 , Issue.AUGUST , pp. 308-314
    • Bonarius, H.P.J.1    Schmid, G.2    Tramper, J.3
  • 17
    • 0032551605 scopus 로고    scopus 로고
    • Metabolic capacity of Bacillus subtilis for the production of purine nucleosides, riboflavin, and folic acid
    • Sauer, U.; Cameron, D. C.; Bailey, J. E. Metabolic capacity of Bacillus subtilis for the production of purine nucleosides, riboflavin, and folic acid. Biotechnol. Bioeng. 1998, 59 (2), 227-238.
    • (1998) Biotechnol. Bioeng. , vol.59 , Issue.2 , pp. 227-238
    • Sauer, U.1    Cameron, D.C.2    Bailey, J.E.3
  • 18
    • 0343035686 scopus 로고    scopus 로고
    • Stoichiometric model of Escherichia coli metabolism: Incorporation of growth-rate dependent biomass compositon and mechanistic energy requirements
    • Pramanik, J.; Keasling, J. D. Stoichiometric Model of Escherichia coli Metabolism: Incorporation of Growth-Rate Dependent Biomass Compositon and Mechanistic Energy Requirements. Biotechnol. Bioeng. 1997, 56, 399-421.
    • (1997) Biotechnol. Bioeng. , vol.56 , pp. 399-421
    • Pramanik, J.1    Keasling, J.D.2
  • 19
    • 0001827017 scopus 로고    scopus 로고
    • Metabolic flux balance analysis
    • Lee, S. Y., Papoutsakis, E. T., Eds.; Springer-Verlag: New York, in press
    • Edwards, J. S.; et al. Metabolic Flux Balance Analysis, in Metabolic Engineering; Lee, S. Y., Papoutsakis, E. T., Eds.; Springer-Verlag: New York, 1999, in press.
    • (1999) Metabolic Engineering
    • Edwards, J.S.1
  • 20
    • 0032485842 scopus 로고    scopus 로고
    • How will bioinformatics influence metabolic engineering?
    • Edwards, J. S.; Palsson, B. O. How will bioinformatics influence metabolic engineering? Biotechnol. Bioeng. 1998, 58, 162-169.
    • (1998) Biotechnol. Bioeng. , vol.58 , pp. 162-169
    • Edwards, J.S.1    Palsson, B.O.2
  • 21
    • 0022654123 scopus 로고
    • A discrete model of bacterial metabolilsm
    • Watson, M. R. A discrete model of bacterial metabolilsm. Comput. Appl. Biosci. 1986, 2, 23-7.
    • (1986) Comput. Appl. Biosci. , vol.2 , pp. 23-27
    • Watson, M.R.1
  • 22
    • 0022493181 scopus 로고
    • Fat synthesis in adipose tissue. An examination of stoichiometric constraints
    • Fell, D. A.; Small, J. A. Fat synthesis in adipose tissue. An examination of stoichiometric constraints. J. Biochem. 1986, 238, 781-786.
    • (1986) J. Biochem. , vol.238 , pp. 781-786
    • Fell, D.A.1    Small, J.A.2
  • 23
    • 0025405421 scopus 로고
    • Simple constrained optimization view of acetate overflow in E. coli
    • Majewski, R. A.; Domach, M. M. Simple constrained optimization view of acetate overflow in E. coli. Biotechnol. Bioeng. 1990, 35, 732-738.
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 732-738
    • Majewski, R.A.1    Domach, M.M.2
  • 24
    • 0022736565 scopus 로고
    • Growth of Saccharomyces cerevisae is controlled by its limited respiratory capacity: Formulation and verification of a hypothesis
    • Sonnleitner, B.; Kappeli, O. Growth of Saccharomyces cerevisae is controlled by its limited respiratory capacity: Formulation and verification of a hypothesis. Biotechnol. Bioeng. 1986, 28, 927-937.
    • (1986) Biotechnol. Bioeng. , vol.28 , pp. 927-937
    • Sonnleitner, B.1    Kappeli, O.2
  • 25
    • 0027723421 scopus 로고
    • Metabolic capabilities of Escherichia coli. II. Optimal growth patterns
    • Varma, A.; Palsson, B. O. Metabolic Capabilities of Escherichia coli. II. Optimal Growth Patterns. J. Theor. Biol. 1983, 165, 503-522.
    • (1983) J. Theor. Biol. , vol.165 , pp. 503-522
    • Varma, A.1    Palsson, B.O.2
  • 26
    • 0028146781 scopus 로고
    • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
    • Varma, A.; Palsson, B. O. Stoichiometric Flux Balance Models Quantitatively Predict Growth and Metabolic By-Product Secretion in Wild-Type Escherichia coli W3110. Appl. Environ. Microbiol. 1994, 60 (10), 3724-3731.
    • (1994) Appl. Environ. Microbiol. , vol.60 , Issue.10 , pp. 3724-3731
    • Varma, A.1    Palsson, B.O.2
  • 27
    • 0029635981 scopus 로고
    • Parametric sensitivity of stoichiometric flux balance models applied to wild-type Escherichia Coli metabolism
    • Varma, A.; Palsson, B. O. Parametric Sensitivity of Stoichiometric Flux Balance Models Applied to Wild-Type Escherichia Coli Metabolism. Biotechnol. Bioeng. 1995, 45, 69-79.
    • (1995) Biotechnol. Bioeng. , vol.45 , pp. 69-79
    • Varma, A.1    Palsson, B.O.2
  • 29
    • 15444350252 scopus 로고    scopus 로고
    • The complete genome sequence of Escherichia coli K-12
    • Blattner, F. R.; et al. The complete genome sequence of Escherichia coli K-12. Science 1997, 277, 1453-1474.
    • (1997) Science , vol.277 , pp. 1453-1474
    • Blattner, F.R.1
  • 32
    • 0017852111 scopus 로고
    • Succinate dehydrogenase-dependent nutritional requirement for succinate in mutants of Escherichia coli K-12
    • Creaghan, I. T.; Guest, J. R. Succinate dehydrogenase-dependent nutritional requirement for succinate in mutants of Escherichia coli K-12. J. Gen. Microbiol. 1978, 107, 1-13.
    • (1978) J. Gen. Microbiol. , vol.107 , pp. 1-13
    • Creaghan, I.T.1    Guest, J.R.2
  • 33
    • 0031453850 scopus 로고    scopus 로고
    • Genome-wide expression monitoring in Saccharomyces cerevisiae
    • Wodicka, L.; et al. Genome-wide expression monitoring in Saccharomyces cerevisiae. Nat. Biotechnol. 1997, 15 1359-1367.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 1359-1367
    • Wodicka, L.1
  • 34
    • 0030669030 scopus 로고    scopus 로고
    • Exploring the metabolic and genetic control of gene expression on a genomic scale
    • DeRisi, J. L.; Iyer, V. R.; Brown, P. O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 1997, 278, 680-686.
    • (1997) Science , vol.278 , pp. 680-686
    • DeRisi, J.L.1    Iyer, V.R.2    Brown, P.O.3
  • 35
    • 0027223982 scopus 로고
    • Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates
    • Varma, A.; Boesch, B. W. Palsson, B. O. Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates. Appl. Environ. Microbiol. 1993, 59 (8), 2465-2473.
    • (1993) Appl. Environ. Microbiol. , vol.59 , Issue.8 , pp. 2465-2473
    • Varma, A.1    Boesch, B.W.2    Palsson, B.O.3
  • 36
    • 0032516028 scopus 로고    scopus 로고
    • The underlying pathway structure of biochemical reaction networks
    • Schilling, C. H.; Palsson, B. O. The underlying pathway structure of biochemical reaction networks. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 4193-4198.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 4193-4198
    • Schilling, C.H.1    Palsson, B.O.2
  • 37
    • 0000311393 scopus 로고    scopus 로고
    • Elementary modes of functioning in biochemical networks
    • Cuthbertson, R., Holcombe, M., Paton, R., Eds.; World Scientific: London
    • Schuster, S.; et al. Elementary modes of functioning in biochemical networks. In Comutation in Cellular and Molecular Biological Systems; Cuthbertson, R., Holcombe, M., Paton, R., Eds.; World Scientific: London, 1996; pp 151-165.
    • (1996) Comutation in Cellular and Molecular Biological Systems , pp. 151-165
    • Schuster, S.1
  • 38
    • 0031105335 scopus 로고    scopus 로고
    • Integrated approaches to the design of media and feeding strategies for fed-batch cultures of animal cells
    • Xie, L.; Wang, D. Integrated approaches to the design of media and feeding strategies for fed-batch cultures of animal cells. Trends Biotechnol. 1997, 15 (3), 109-113.
    • (1997) Trends Biotechnol. , vol.15 , Issue.3 , pp. 109-113
    • Xie, L.1    Wang, D.2
  • 39
    • 0033580813 scopus 로고    scopus 로고
    • Properties of the Haemophilus influenzae Rd metabolic genotype
    • in press
    • Edwards, J. S.; Palsson, B. O. Properties of the Haemophilus influenzae Rd metabolic genotype. J. Biol. Chem., in press.
    • J. Biol. Chem.
    • Edwards, J.S.1    Palsson, B.O.2
  • 40
    • 0008293216 scopus 로고
    • A chemically defined medium for growth, transformation, and isolation of nutritional mutants of Hemophilus influenzae
    • Talmadge, M. B.; Herriott, R. M. A chemically defined medium for growth, transformation, and isolation of nutritional mutants of Hemophilus influenzae. Biochem. Biophys. Res. Commun. 1960, 2 (3), 203-206.
    • (1960) Biochem. Biophys. Res. Commun. , vol.2 , Issue.3 , pp. 203-206
    • Talmadge, M.B.1    Herriott, R.M.2
  • 41
    • 0031281740 scopus 로고    scopus 로고
    • Oligomer-chip technology
    • Hoheisel, J. D. Oligomer-chip technology. Trends Biotechnol. 1997, 15, 465-469.
    • (1997) Trends Biotechnol. , vol.15 , pp. 465-469
    • Hoheisel, J.D.1
  • 42
    • 0031963203 scopus 로고    scopus 로고
    • DNA chips: State-of-the art
    • Ramsay, G. DNA chips: State-of-the art Nat. Biotechnol. 1998, 16, 40-44.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 40-44
    • Ramsay, G.1
  • 43
    • 0029812283 scopus 로고    scopus 로고
    • A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization
    • Shalon, D.; Smith, S. J.; Brown, P. O. A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Res. 1996, 6, 639-645.
    • (1996) Genome Res. , vol.6 , pp. 639-645
    • Shalon, D.1    Smith, S.J.2    Brown, P.O.3
  • 44
    • 0031800106 scopus 로고    scopus 로고
    • Microarrays: Biotechnology's discovery platform for functional genomics
    • Schena, M.; et al. Microarrays: biotechnology's discovery platform for functional genomics. Trends Biotechnol. 1998, 16, 301-306.
    • (1998) Trends Biotechnol. , vol.16 , pp. 301-306
    • Schena, M.1
  • 45
    • 84984770035 scopus 로고    scopus 로고
    • Databases for gene expression
    • Church, G. M. Databases for gene expression. Nat. Biotechnol. 1996, 14, 828.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 828
    • Church, G.M.1
  • 46
    • 0030767109 scopus 로고    scopus 로고
    • Mycoplasma genes: A case for reflective annotation
    • Pollack, J. D. Mycoplasma genes: a case for reflective annotation. Trends Microbiol. 1997, 5 (10), 413-418.
    • (1997) Trends Microbiol. , vol.5 , Issue.10 , pp. 413-418
    • Pollack, J.D.1
  • 47
    • 0345346570 scopus 로고    scopus 로고
    • Metabolic pathway analysis: Basic concepts and scientific applications
    • Schilling, C. H.; et al. Metabolic Pathway Analysis: Basic Concepts and Scientific Applications. Biotechnol. Prog. 1999, 15, xxx.
    • (1999) Biotechnol. Prog. , vol.15
    • Schilling, C.H.1


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